Method and apparatus for measuring blood constituent counts
    131.
    发明授权
    Method and apparatus for measuring blood constituent counts 失效
    用于测量血液成分计数的方法和装置

    公开(公告)号:US4683579A

    公开(公告)日:1987-07-28

    申请号:US813978

    申请日:1985-12-27

    Abstract: Blood constituents such as red cells, white cells, and platelets are centrifuged into layers in a capillary tube and the true extent of one or more of the layers is measured photometrically. Each layer to be measured is optically scanned by a sequence of scanning operations with the actual extent of each layer traverse being recorded in a computer. After each layer has been completely circumferentially scanned and each traverse recorded, the computer determines the true average axial dimension for each layer and computes, through prior input, the actual constituent count for each constituent layer.

    Abstract translation: 将血液成分如红细胞,白细胞和血小板在毛细管中离心分层,并用光度法测量一层或多层的真实程度。 通过扫描操作的顺序光学地扫描要测量的每个层,每个层横穿的实际程度被记录在计算机中。 在每个层被完全周向扫描并且每个遍历记录之后,计算机确定每个层的真实平均轴向尺寸,并且通过现有输入计算每个构成层的实际构成计数。

    Automatic refractometer
    132.
    发明授权

    公开(公告)号:US4640616A

    公开(公告)日:1987-02-03

    申请号:US678932

    申请日:1984-12-06

    Inventor: John K. Michalik

    CPC classification number: G01N21/43 G01J2001/448 G01N2021/414 G01N2201/126

    Abstract: An automatic refractometer comprising a photosensitive device having a relatively narrow dynamic range in the form of a linear scanned array including a plurality of photoelectric elements each providing an output pulse during a scan and the amplitude of each pulse being determined by the amount of illumination of the corresponding element by incident light, an optical system for directing light onto the array in a manner such that the particular photoelectric elements of the array which are illuminated by the light are determined by the index of refraction of a light transmitting substance placed in operative association with the optical system, a circuit for converting signals from the array into digital signals containing information as to the amplitudes of the signals from the array, a digital processing circuit for storing respective signals from reference and sample substances placed in operative association with the optical system and for computing the index of refraction of the sample substance by means of a comparison of the stored reference and sample information, and apparatus for providing a read out of the computed result. The digital processing circuit also calculates the percent solids in the sample substance, and the circuit also includes a plurality of channels for containing information to provide different interpretation of the index of refraction computed thereby. The circuit for converting array signals into digital signals comprises a peak detector circuit for detecting peak amplitudes of signals obtained from scanning the array and an analog-to-digital converter for providing digital signals containing information as to peak amplitudes of the array signals. There is also provided arrangements for measuring the temperatures of the sample substance and comparing to a reference for applying a temperature correction to the computed index of refraction, monitoring and regulating the temperature of the component of the optical system to which the sample substance is exposed, and monitoring and regulating the intensity of light incident on the array.

    ADAPTIVE SUBTRACTION FOR C-SIM MICROSCOPY
    133.
    发明公开

    公开(公告)号:US20240338792A1

    公开(公告)日:2024-10-10

    申请号:US18296859

    申请日:2023-04-06

    Inventor: John Eichorst

    Abstract: Computer-implemented image processing methods with a computer processor and computer memory, comprise accessing, from the computer memory, a non-toroidal beam image component comprising a set of pixel intensities across an imaging area and a toroidal beam image component comprising a set of pixel intensities across the imaging area, scaling, with the computer processor, an image intensity of at least one pixel of one of the non-toroidal or toroidal beam image components by a ratio between a peak non-toroidal beam imaging pixel intensity across the imaging area and a peak toroidal beam imaging intensity across the imaging area to produce a scaled image intensity, and determining a difference between the scaled image intensity of the at least one pixel of the non-toroidal or toroidal image components and an image intensity of at least one pixel of the other of the non-toroidal or toroidal image components to form at least a portion of an image.

    PORTABLE HYPERSPECTRAL SYSTEM
    135.
    发明公开

    公开(公告)号:US20240210310A1

    公开(公告)日:2024-06-27

    申请号:US18553730

    申请日:2021-04-02

    Abstract: A capsule hyperspectral system can include: an imaging capsule having an illumination system having a plurality of light emitters configured for emitting a plurality of different lighting illuminations from the imaging capsule and a hyperspectral imaging system having at least one imaging sensor, wherein the illumination system and hyperspectral imaging system are cooperatively configured to illuminate a target with a sequence of different lighting illuminations and image the target during each of the different lighting illuminations in the sequence, and a hyperspectral processing system having at least one processor, wherein the hyperspectral processing system is operably coupled with the hyperspectral imaging system and configured to receive images of the target therefrom and generate a multispectral reflectance data cube of the target from the received images of the target.

    COMPOSITE DATA FOR DEVICE METROLOGY
    137.
    发明公开

    公开(公告)号:US20240111256A1

    公开(公告)日:2024-04-04

    申请号:US18339982

    申请日:2023-06-22

    CPC classification number: G05B13/0265 G01N2201/126

    Abstract: A machine learning model that uses composite metrology data determines at least one parameter of a device under test using measured metrology data from the device. The composite metrology data is generated by merging measured metrology data from a reference device with synthetic metrology data calculated from a model of the reference device. The composite metrology data may be generated further based on a synthetic metrology data calculated from a model for a modified reference device. The modified reference device may be generated using variations of at least one parameter of the model to expand the parameter space of the training range.

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