公开(公告)号：US4167338A

公开(公告)日：1979-09-11

申请号：US831134

申请日：1977-09-07

Applicant: Thaddaus Kraus

Inventor： Thaddaus Kraus

IPC: G01J3/433 ,  G01J3/42 ,  G01J3/48

CPC classification number: G01J3/433

Abstract: A method for determining the quantity ratio of two components of a multi-substance mixture whose absorption bands are adjacent to each other and overlap comprises using an interference filter which is rotated in a uniform rotation about a first axis through the filter plane which forms with a perpendicular erected on the filter plane a fixed angle .beta. which is not equal to zero. The filter is rotatably arranged about a second axis through the filter plane and the method is characterized by adjusting the angle .alpha. which the axis of rotation forms with the ray in the range of .beta. is less than .alpha. so that a signal corresponding to the first derivative of the spectral intensity distribution of the radiation transmitted by the substance mixture just passes through zero and a quantity correlated with this angle is used as a measure of the quantity ratio. The radiation modulator for determining the quantity ratio includes a housing having an opening for the passage of the light ray therethrough and a filter in the housing in the path of the beam. The filter is mounted for rotation about a first axis comprising the axis of the filter and is mounted for pivoting about a second axis also going through the filter. The first axis is such that the area normal thereof forms with the first axis a fixed angle .beta. and the first axis is rotatable about the second axis and an angle .alpha. is formed between the first axis in the ray direction which may be read and indicated and the filter is adjustable to vary the angle.

Abstract translation: 一种用于确定其吸收带彼此相邻并且重叠的多物质混合物的两种组分的量比的方法包括使用干涉滤光器，所述干涉滤光器以围绕第一轴的均匀旋转通过过滤平面旋转，所述过滤平面与 垂直竖立在过滤平面上，固定角度β不等于零。 过滤器绕第二轴线可旋转地布置通过过滤器平面，并且该方法的特征在于调整旋转轴线形成的角度α，β的范围内的光线小于α，使得对应于一阶导数的信号 由物质混合物传播的辐射的光谱强度分布刚好通过零，并且与该角度相关的量被用作量比的量度。 用于确定数量比率的辐射调制器包括具有用于光线通过的开口的壳体和在梁的路径中的壳体中的过滤器。 安装过滤器以围绕包括过滤器的轴线的第一轴线旋转，并且安装成围绕也穿过过滤器的第二轴线枢转。 第一轴线使得其第一轴线与第一轴线形成固定角度β并且第一轴线可围绕第二轴线旋转并且在可以被读取和指示的射线方向上的第一轴线之间形成角度α，并且 过滤器可调，以改变角度。

公开(公告)号：US4090792A

公开(公告)日：1978-05-23

申请号：US698559

申请日：1976-06-22

Applicant: Konrad Bunge

Inventor： Konrad Bunge

IPC: G01J3/433 ,  G01N21/27 ,  G01J3/50 ,  G01N21/24

CPC classification number: G01J3/433

Abstract: In a single beam photometer the transmitted radiation is modulated in respect of wavelength. As the modulator, an interference pattern filter is used, whose transmitted wavelength agrees in the middle approximately with the absorption band to be measured. The interference pattern filter is either arranged so as to be rotatable in the beam path or oscillates at right angles to the optical axis. The electronic system is tuned to the first harmonic of the interference pattern filter frequency; i.e. the effects of signals of other frequencies are suppressed by the electronics.

Abstract translation: 在单光束光度计中，透射辐射相对于波长进行调制。 作为调制器，使用干涉图案滤波器，其透射波长近似于待测量的吸收带。 干涉图案滤波器被布置成可以在光束路径中旋转或者与光轴成直角振荡。 电子系统调谐到干涉图案滤波频率的一次谐波; 即其他频率的信号的影响被电子设备抑制。

公开(公告)号：US4033699A

公开(公告)日：1977-07-05

申请号：US582183

申请日：1975-05-30

Applicant: John G. Bayly ,  Ronald J. Booth

Inventor： John G. Bayly ,  Ronald J. Booth

IPC: G01N21/35 ,  G01N21/59 ,  G21C17/00 ,  G01N21/26

CPC classification number: G01J3/433 ,  G21C17/028

Abstract: An apparatus for monitoring the concentration of a vapor, such as heavy water, having at least one narrow bandwidth in its absorption spectrum, in a sample gas such as air. The air is drawn into a chamber in which the vapor content is measured by means of its radiation absorption spectrum. High sensitivity is obtained by modulating the wavelength at a relatively high frequency without changing its optical path, while high stability against zero drift is obtained by the low frequency interchange of the sample gas to be monitored and of a reference sample. The variable HDO background due to natural humidity is automatically corrected.

Abstract translation: 一种用于在诸如空气的样品气体中监测其吸收光谱中具有至少一个窄带宽的蒸汽浓度例如重水的装置。 空气被吸入其中通过其辐射吸收光谱测量蒸汽含量的室。 通过在不改变其光路的情况下以相对较高的频率调制波长来获得高灵敏度，而通过要监测的样品气体和参考样品的低频交换获得了对零漂移的高稳定性。 由于自然湿度导致的可变HDO背景自动校正。

公开(公告)号：US3641350A

公开(公告)日：1972-02-08

申请号：US3641350D

申请日：1970-09-08

Applicant: US NAVY

Inventor： PETROPOULAS SPYROS K ,  JEHLE ROBERT E ,  HALBERSTAM MENDEL M

IPC: G01J3/00 ,  G01J3/433 ,  G01J5/52 ,  G01J3/34

CPC classification number: G01J3/433 ,  G01J3/021 ,  G01J5/52

Abstract: The radiant energy from a known live source impinges on a radiation collector which in turn directs the energy through a movable slit on to a rotating reticle having alternate reflecting and transmitting segments. A reference source also directs energy on to the reticle and the reticle output is directed toward a sensor whose output is processed by a differential amplifier and a signal amplifier. A reference phase generator circuit controls the gain of the differential amplifier. The output of the signal amplifier is further processed to provide only the low frequencies, which are then amplified and analyzed to provide a scintillation spectrum. A shimmer output is obtained by eliminating the low frequencies and applying the resultant to a limiter and a discriminator. The modulation transfer function is derived by combining, in an operational amplifier, the low-passed frequencies from the signal amplifiers and the peak detected high frequencies.

Abstract translation: 来自已知有源光源的辐射能量照射在辐射收集器上，辐射收集器又将能量通过可移动狭缝引导到具有交替反射和传输段的旋转掩模版上。 参考源还将能量引导到掩模版，并且光栅输出被引导到传感器，其输出由差分放大器和信号放大器处理。 参考相位发生器电路控制差分放大器的增益。 进一步处理信号放大器的输出以仅提供低频，然后将其放大和分析以提供闪烁光谱。 通过消除低频并将结果应用于限幅器和鉴频器来获得闪烁输出。 调制传递函数是通过在运算放大器中组合来自信号放大器的低通频率和检测到的峰值的高频导出的。

公开(公告)号：US3578866A

公开(公告)日：1971-05-18

申请号：US3578866D

申请日：1969-05-09

Applicant: CALIFORNIA INST OF TECHN

Inventor： KOHLER BRYAN E ,  DUBIN ALAN S

IPC: G01J3/433 ,  G01J3/00 ,  G01J3/42

CPC classification number: G01J3/433

Abstract: An optical spectrometer is adapted to provide differential wavelength modulation of a spectral signal by vibrating a photosensitive cell in the focal plane of the spectrograph. A synchronous detector is employed to demodulate the output signal of the photosensitive cell, and thereby provide to a recording device a signal that is the derivative of the spectral signal.

公开(公告)号：US3565567A

公开(公告)日：1971-02-23

申请号：US3565567D

申请日：1968-06-25

Applicant: BAUSCH & LOMB

Inventor： RAINS STEPHEN D

IPC: G01J3/433 ,  G01N21/31 ,  G01J3/30 ,  G01J3/12

CPC classification number: G01N21/3103 ,  G01J3/433

Abstract: A BEAM OF RADIATION FROM A CONTINUUM SOURCE IS DIRECTED THROUGH AN ATOMIC VAPOR. A RADIATION SENSITIVE DETECTOR MONITORS THE RADIATION FROM THE ATOMIC VAPOR. A MODULATOR IS INCLUDED SO THAT THE DETECTOR RECEIVES A WAVELENGTH MODULATED SIGNAL THAT PERIODICALLY INCLUDES THE WAVELENGTH OF THE SPECTRAL LINE CHARACTERISTIC OF THE ELEMENT TESTED. THE RADIATION SENSITIVE DETECTOR GENERATES A SIGNAL INDICATING THE PRESENCE AND/OR CONCENTRATION OF THE ELEMENT BY DETERMINING THE AMOUNT OF RADIATION ABSORBED, OR THE INTENSITY OF ATOMIC FLUORESCENCE EMITTED.

公开(公告)号：US20240167877A1

公开(公告)日：2024-05-23

申请号：US18514008

申请日：2023-11-20

Applicant: Government of the United States of America, as represented by the Secretary of Commerce

Inventor： Young Jong Lee

IPC: G01J3/433 ,  G01J3/02 ,  G01N21/31

CPC classification number: G01J3/433 ,  G01J3/0229 ,  G01N21/3103

Abstract: A method of determining an optical spectrum for a sample substance includes splitting a source beam into a reference beam and a sample beam, periodically modulating the intensity of the beams out of phase of each other, directing the reference beam through a reference substance and the sample beam through the sample substance. The beams are then recombined, and a single detector detects the intensity difference at the modulation frequency to determine the spectrum of the sample substance.

公开(公告)号：US11704886B2

公开(公告)日：2023-07-18

申请号：US18045695

申请日：2022-10-11

Applicant: Shrenik Deliwala

Inventor： Shrenik Deliwala

IPC: G01J3/28 ,  G01J3/433 ,  G01N21/25 ,  A61B5/00 ,  G01N21/3504 ,  G01N21/95 ,  A61B5/1455

CPC classification number: G01J3/433 ,  G01J3/2823 ,  G01N21/255 ,  A61B5/14551 ,  A61B5/742 ,  G01J2003/4334 ,  G01N21/3504 ,  G01N21/9501

Abstract: Modulation-encoded light, using different spectral bin coded light components, can illuminate a stationary or moving (relative) target object or scene. Response signal processing can use information about the respective different time-varying modulation functions, to decode to recover information about a respective response parameter affected by the target object or scene. Electrical or optical modulation encoding can be used. LED-based spectroscopic analysis of a composition of a target (e.g., SpO2, glucose, etc.) can be performed; such can optionally include decoding of encoded optical modulation functions. Baffles or apertures or optics can be used, such as to constrain light provided by particular LEDs. Coded light illumination can be used with a focal plane array light imager receiving response light for inspecting a moving semiconductor or other target. Encoding can use orthogonal functions, such as an RGB illumination sequence, or a sequence of combinations of spectrally contiguous or non-contiguous colors.

公开(公告)号：US20230204497A1

公开(公告)日：2023-06-29

申请号：US18111740

申请日：2023-02-20

Applicant: Apple Inc.

Inventor： Miikka M. Kangas ,  Mark Alan Arbore ,  David I. Simon ,  Michael J. Bishop ,  James W. Hillendahl ,  Robert Chen

IPC: G01N21/27 ,  G01N21/35 ,  G01N21/47 ,  G01J3/32 ,  G01J3/36 ,  G01J3/433 ,  G01J3/447 ,  G01J3/02 ,  G01J3/42

CPC classification number: G01N21/276 ,  G01N21/35 ,  G01N21/474 ,  G01N21/4785 ,  G01J3/32 ,  G01J3/36 ,  G01J3/433 ,  G01J3/447 ,  G01J3/0286 ,  G01J3/42 ,  G01N2021/4709 ,  G01N2201/0221 ,  G01N2201/12723 ,  G01N21/49

Abstract: This relates to systems and methods for measuring a concentration and type of substance in a sample at a sampling interface. The systems can include a light source, optics, one or more modulators, a reference, a detector, and a controller. The systems and methods disclosed can be capable of accounting for drift originating from the light source, one or more optics, and the detector by sharing one or more components between different measurement light paths. Additionally, the systems can be capable of differentiating between different types of drift and eliminating erroneous measurements due to stray light with the placement of one or more modulators between the light source and the sample or reference. Furthermore, the systems can be capable of detecting the substance along various locations and depths within the sample by mapping a detector pixel and a microoptics to the location and depth in the sample.

公开(公告)号：US20230160822A1

公开(公告)日：2023-05-25

申请号：US18100276

申请日：2023-01-23

Applicant: TODOS MEDICAL LTD.

Inventor： Joseph KAPELUSHNIK ,  Shaul MORDECHAI ,  Ilana NATHAN ,  Udi ZELIG ,  Rami ZIGDON

IPC: G01N21/63 ,  G01J3/433 ,  G01N21/35 ,  G01N21/3563 ,  G01N15/14

CPC classification number: G01N21/63 ,  G01J3/433 ,  G01N21/35 ,  G01N21/3563 ,  G01N15/1456 ,  G01N2021/3595 ,  G01N2015/008

Abstract: A system is provided comprising an FTIR spectrometer configured to obtain a Fourier Transformed infrared (FTIR) spectrum of a Peripheral Blood Mononuclear Cells (PBMC) sample of the subject; a data processor operable with the FTIR spectrometer, and configured to analyze the infrared (IR) spectrum of the Peripheral Blood Mononuclear Cells (PBMC) sample of the subject by assessing a characteristic of the sample of the subject at at least one wavenumber; and an output unit, configured to generate an output indicative of the presence of a solid tumor, based on the infrared (IR) spectrum. Other embodiments are also provided.