公开(公告)号：US20170219484A1

公开(公告)日：2017-08-03

申请号：US15500658

申请日：2014-08-18

Applicant: Foss Analytical A/S

Inventor： Per Waaben HASSEN ,  Henrik Vilstrup JUHL ,  Lars NOERGAARD ,  Andreas BAUM ,  Joern Dalgaard MIKKELSEN

IPC: G01N21/3577 ,  G06F19/00 ,  G01N33/14 ,  C12Q1/37 ,  G01N33/04 ,  G01N21/75

CPC classification number: G01N21/3577 ,  C12Q1/37 ,  G01N21/1717 ,  G01N21/75 ,  G01N33/04 ,  G01N33/143 ,  G01N33/146 ,  G01N2201/127 ,  G01N2201/129 ,  G01N2333/9648 ,  G16C10/00 ,  G16C20/10 ,  G16C20/70

Abstract: A method of determining a constituent related sample property of a multi-constituent sample comprising: subjecting the sample to a perturbation selected to induce a time dependent change in measurement data associated with a constituent related to the sample property to be determined; recording a time-series of measurement data following subjecting the sample to the perturbation; and determining the sample property from the application to the recorded time-series of measurement data of a calibration correlating the sample property with time-series of measurement data, said calibration being empirically derived from chemometric time-series modelling of time-series measurement data recorded for each of a plurality of reference samples following subjecting each reference sample to the perturbation, each reference sample having a different known values of the sample property.

公开(公告)号：US09625376B2

公开(公告)日：2017-04-18

申请号：US14772555

申请日：2013-03-22

Applicant: Foss Analytical A/S

Inventor： Maja Kirstine Elsoee ,  Henrik Vilstrup Juhl ,  Thomas Nikolajsen

IPC: G01J5/00 ,  G01N21/3563 ,  G01J3/443 ,  G01N33/24 ,  G01N21/35 ,  G01N21/71 ,  G01J3/28 ,  G01N1/28 ,  G01J1/08

CPC classification number: G01N21/3563 ,  G01J3/28 ,  G01J3/443 ,  G01J2001/083 ,  G01N1/286 ,  G01N21/35 ,  G01N21/718 ,  G01N33/24 ,  G01N2201/129

Abstract: A system (102) for determining properties of a sample (114) comprises a LIBS detector (104,106) and an infra-red absorption detector (108,110) for interrogating a sample (114) to generate LIBS spectral data and infra-red absorption spectral data respectively; and a data processor (112) adapted to apply at least one chemometric prediction model, each constructed to link, preferably quantitatively link, features of both LIBS and absorption spectral data to a different specific property of the sample, to a combined dataset derived from at least portions of both the LIBS and the absorption data to generate therefrom a determination, preferably a quantitative determination, of the specific property linked by that model.

公开(公告)号：US12055506B2

公开(公告)日：2024-08-06

申请号：US17632043

申请日：2020-05-28

Applicant: Foss Analytical A/S

Inventor： Per Waaben Hansen ,  Mads Lykke Andersen

IPC: G01N27/06 ,  G01N21/3577 ,  G01N33/04

CPC classification number: G01N27/06 ,  G01N21/3577 ,  G01N33/04

Abstract: A method of standardizing an output of an electrical property sensor includes calculating a reference magnitude (Condr) of an electrical property of an electrically conductive liquid, based on obtaining, by a spectrometer, spectral data resulting from an interaction of light with the electrically conductive liquid, and applying, in a data processor, a mathematical model to the spectral data to calculate the reference magnitude (Condr) of the electrical property, wherein the mathematical model links the spectral data to magnitudes of the electrical property; comparing, in the data processor, a measured magnitude (Condm) of the electrical property of the electrically conductive liquid with a reference magnitude (Condr) of the electrical property, wherein the measured magnitude (Condm) of the electrical property is obtained with the electrical property sensor; determining, in the data processor, a standardization factor (F) dependent on a ratio of the reference magnitude (Condr) and the measured magnitude (Condm).

公开(公告)号：US11965823B2

公开(公告)日：2024-04-23

申请号：US17629532

申请日：2020-05-29

Applicant: Foss Analytical A/S

Inventor： Per Waaben Hansen ,  Jeppe Sandvik Clausen

IPC: G01N21/27 ,  G01N21/3577 ,  G01N21/35 ,  G01N33/04

CPC classification number: G01N21/274 ,  G01N21/3577 ,  G01N2021/3595 ,  G01N33/04 ,  G01N2201/1214 ,  G01N2201/129

Abstract: A method of correcting for an amplitude change in a spectrometric instrument output includes: exposing a sample in a sample holder to electromagnetic radiation at a plurality of wavenumbers; detecting electromagnetic absorption intensities in the sample at the plurality of wavenumbers; providing to a computer device the detected electromagnetic absorption intensities indexed against wavenumber as spectral data; applying in the computer device a mathematical transform (Icorr) to the spectral data to correct for an amplitude change in the spectrometric instrument's output and calculated by determining a difference (Δ(SBZ)/) between first derivatives of a logarithmic transformation of spectral data (SBZ) from the zero material sample at two different wavenumber ranges (log10(SBZ(x1))/ and log10(SBZ(x2))/); and calculating the mathematical transform (Icorr) as a function inversely dependent on the determined difference (Δ(SBZ)/).

公开(公告)号：US20230381780A1

公开(公告)日：2023-11-30

申请号：US18249808

申请日：2021-10-13

Applicant: Foss Analytical A/S

Inventor： Darwin PALIMA ,  Soeren Christian PEDERSEN ,  Bo Melholt NIELSEN

IPC: B01L3/00 ,  B01F31/31 ,  B01F31/20 ,  B03C1/28 ,  B03C1/30

CPC classification number: B01L3/502761 ,  B01F31/31 ,  B01F31/265 ,  B03C1/288 ,  B03C1/30 ,  B03C2201/18 ,  B01F2101/23

Abstract: A mixer includes a mixing chamber and a motor mechanically connected to the mixing chamber. The mixing chamber comprises a suspended elongate rigid tube section having a top end and an open bottom end, and a flexible tube section extending downwards from the open bottom end. The motor comprises a vibration motor mechanically coupled to the suspended elongate rigid tube section at the top end of the suspended elongate rigid tube section.

公开(公告)号：US20230011975A1

公开(公告)日：2023-01-12

申请号：US17784870

申请日：2020-10-15

Applicant: Foss Analytical A/S

Inventor： Jeppe Sandvik CLAUSEN

IPC: G01J3/427 ,  G01N21/03 ,  G01N21/27

Abstract: A method for determining an optical pathlength through a cuvette of a spectrophotometric apparatus includes obtaining a first single beam spectrum of a liquid zero-material at least in a first energy region in which the liquid zero-material absorbs at least a portion of incident optical radiation; obtaining a second single beam spectrum of a second liquid at least in the first energy region, the second liquid having a composition excluding the liquid zero-material and having no absorption of incident optical radiation in the first energy region; determining a dual beam spectrum of the liquid zero-material relative to the second liquid at least in the first energy region from the first and second single beam spectra; and calculating an optical pathlength through the cuvette based on processing spectral information obtained from the first energy region of the determined dual beam spectrum.

公开(公告)号：US20220252505A1

公开(公告)日：2022-08-11

申请号：US17629532

申请日：2020-05-29

Applicant: Foss Analytical A/S

Inventor： Per Waaben HANSEN ,  Jeppe Sandvik CLAUSEN

IPC: G01N21/27 ,  G01N21/3577

Abstract: A method of correcting for an amplitude change in a spectrometric instrument output includes: exposing a sample in a sample holder to electromagnetic radiation at a plurality of wavenumbers; detecting electromagnetic absorption intensities in the sample at the plurality of wavenumbers; providing to a computer device the detected electromagnetic absorption intensities indexed against wavenumber as spectral data; applying in the computer device a mathematical transform (Icorr) to the spectral data to correct for an amplitude change in the spectrometric instrument's output and calculated by determining a difference (Δ(SBZ)/) between first derivatives of a logarithmic transformation of spectral data (SBZ) from the zero material sample at two different wavenumber ranges (log10(SBZ(x1))/ and log10(SBZ(x2))/); and calculating the mathematical transform (Icorr) as a function inversely dependent on the determined difference (Δ(SBZ)/).

公开(公告)号：US11243147B2

公开(公告)日：2022-02-08

申请号：US17038531

申请日：2020-09-30

Applicant: Foss Analytical A/S

Inventor： Thomas Nikolajsen ,  Daniel Aden

IPC: G01N1/28 ,  G01N1/44 ,  G01N33/483 ,  G01N21/71

Abstract: A method for preparing a sample of organic material for laser induced breakdown spectroscopy (LIBS) may include obtaining granular organic material, forming a portion of the granular organic material into a sample pellet, and searing the organic material. The searing may include searing only an exposed end surface of the sample pellet on which LIBS analysis is to be performed. The method may include pressing the seared sample pellet to consolidate the material comprising the seared end surface.

公开(公告)号：US20210255182A1

公开(公告)日：2021-08-19

申请号：US17270981

申请日：2019-08-07

Applicant: Foss Analytical A/S

Inventor： Rasmus VISTISEN ,  Jakob Frederik Schoendorff ENGELL

IPC: G01N33/558 ,  B01L3/00

Abstract: A device comprises: a receptacle having a bottom wall portion closing a first end of the receptacle to delimit an inner space and having a receptacle opening at an opposite second end; a compartment for holding a lateral flow assay test strip, the compartment having a lower portion located closer to the first end than to the second end; a passageway in fluid communication with the lower portion of the compartment; and a lid configured to overlay the receptacle opening and comprising a body portion. A sample receiving portion is located in said body portion and is arranged in fluid communication with the inner space. The passageway is delimited by a first opening into the lower portion of the compartment and a second opening in the lid.

公开(公告)号：US20210213443A1

公开(公告)日：2021-07-15

申请号：US17270990

申请日：2019-08-07

Applicant: Foss Analytical A/S

Inventor： Rasmus VISTISEN ,  Jakob Frederik Schoendorff ENGELL

IPC: B01L3/00 ,  B01L3/02

Abstract: A sampling device comprises a receptacle having an inner material receiving space defined by a side wall portion and a bottom wall portion and having a receptacle opening; and a sample container being adapted to close the receptacle opening when collocated with the receptacle. The sample container includes: a sample receiving portion which, when collocated with the receptacle is located in liquid communication with the inner material receiving space; a sample well positioned radially outside of the sample receiving portion in a direction perpendicular to a longitudinal axis, the sample well having a well opening; a liquid passageway for directing liquid from the sample receiving portion towards the well opening; a container having a container opening; and a liquid impermeable barrier for preventing liquid entering the container opening from the sample receiving portion.