公开(公告)号：US12078650B2

公开(公告)日：2024-09-03

申请号：US16295179

申请日：2019-03-07

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Daniel Mueller

IPC: G01N35/04 ,  G01N35/10 ,  B01D35/02 ,  B01F25/00 ,  B01L3/00 ,  B01L3/02 ,  B04B5/04 ,  B04B11/04 ,  B23P19/00 ,  B65B7/16 ,  B65B7/28 ,  G01N1/28 ,  G01N21/77 ,  G01N33/543 ,  G01N35/00 ,  G01N35/02

CPC classification number: G01N35/04 ,  G01N35/10 ,  B01D35/02 ,  B01F25/00 ,  B01L3/00 ,  B01L3/02 ,  B04B5/04 ,  B04B11/04 ,  B23P19/00 ,  B65B7/16 ,  B65B7/28 ,  G01N1/28 ,  G01N21/77 ,  G01N33/543 ,  G01N35/00 ,  G01N2035/00346 ,  G01N35/02 ,  G01N2035/0405

Abstract: A method for unsealing an opening of a laboratory sample container containing a sample is presented. The opening is sealed by a closure attached to the laboratory sample container by an adhesive. An adhesive strength of the adhesive is lowerable by treatment. The method comprises treating the adhesive such that its adhesive strength is lowered and removing the closure from the laboratory sample container.

公开(公告)号：US11169061B2

公开(公告)日：2021-11-09

申请号：US16542786

申请日：2019-08-16

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Claudio Cherubini ,  Martin Kopp ,  Nenad Milicevic ,  Daniel Mueller ,  Emad Sarofim ,  Goran Savatic

IPC: G01N1/40 ,  G01N15/04 ,  G01N35/00 ,  G01N35/10 ,  B01L3/00 ,  C12M1/00 ,  B04B5/04 ,  B04B7/08 ,  B04B11/04 ,  B04B13/00

Abstract: A method and system for processing particles contained in a liquid biological sample is presented. The method uses a rotatable vessel for processing particles contained in a liquid biological sample. The rotatable vessel has a longitudinal axis about which the vessel is rotatable, an upper portion having a top opening for receiving the liquid containing the particles, a lower portion for holding the liquid while the rotatable vessel is resting, the lower portion having a bottom, and an intermediate portion located between the upper portion and the lower portion, the intermediate portion having a lateral collection chamber for holding the liquid while the rotatable vessel is rotating. The method employs dedicated acceleration and deceleration profiles for sedimentation and re-suspension of the particles of interest.