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1.
公开(公告)号:US11226348B2
公开(公告)日:2022-01-18
申请号:US15843867
申请日:2017-12-15
Applicant: Roche Diagnostics Operations, Inc.
Inventor: Urs Vollenweider , Gottlieb Schacher , Goran Savatic , Marco Maetzler , Christoph Ludwig , Christian Loewenstein , Yves Laloux , Rik Harbers , Matthias Edelmann , Andreas Drechsler
IPC: G01N35/04
Abstract: A storage module for a laboratory automation system, a method of operating a laboratory automation system, and a laboratory automation system are presented. Items used by laboratory stations are stored centrally in a storage module and can be transported to the laboratory stations using a laboratory sample distribution system.
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公开(公告)号:US20200033240A1
公开(公告)日:2020-01-30
申请号:US16542786
申请日:2019-08-16
Applicant: Roche Diagnostics Operations, Inc.
Inventor: Claudio Cherubini , Martin Kopp , Nenad Milicevic , Daniel Mueller , Emad Sarofim , Goran Savatic
IPC: G01N1/40 , B01L3/00 , C12M1/00 , B04B5/04 , B04B7/08 , B04B11/04 , B04B13/00 , G01N15/04 , G01N35/00 , G01N35/10
Abstract: A method and system for processing particles contained in a liquid biological sample is presented. The method uses a rotatable vessel for processing particles contained in a liquid biological sample. The rotatable vessel has a longitudinal axis about which the vessel is rotatable, an upper portion having a top opening for receiving the liquid comprising the particles, a lower portion for holding the liquid while the rotatable vessel is resting, the lower portion having a bottom, and an intermediate portion located between the upper portion and the lower portion, the intermediate portion having a lateral collection chamber for holding the liquid while the rotatable vessel is rotating. The method employs dedicated acceleration and deceleration profiles for sedimentation and re-suspension of the particles of interest.
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3.
公开(公告)号:US20150093771A1
公开(公告)日:2015-04-02
申请号:US14558152
申请日:2014-12-02
Applicant: Roche Diagnostics Operations, Inc.
Inventor: Patrick Griss , Rainer Jaeggi , Goran Savatic , Vuk Siljegovic
CPC classification number: B01L3/50273 , B01L2200/10 , B01L2300/0654 , B01L2300/0803 , B01L2300/0887 , B01L2300/168 , B01L2400/0409 , B01L2400/0688 , C12Q1/54 , G01N21/07 , G01N33/491 , Y10T436/144444 , Y10T436/146666 , Y10T436/15 , Y10T436/166666 , Y10T436/171538 , Y10T436/175383 , Y10T436/201666 , Y10T436/204165
Abstract: An analytical device for analysis of chemical or biological samples, a method of using such a device, based on rotation of the device, integrated sample dosing and optical detection, and a system comprising such a device are disclosed. The analytical device comprises a device body having a liquid processing unit. The liquid processing unit comprises a mixing chamber for mixing a sample with a reagent, a sample dosing chamber for delivering a defined volume of the sample to the mixing chamber, and a reagent channel for delivering the reagent to be mixed with the sample, wherein the mixing chamber also serves as a detection chamber.
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公开(公告)号:US20210072270A1
公开(公告)日:2021-03-11
申请号:US17008778
申请日:2020-09-01
Applicant: Roche Diagnostics Operations, Inc.
Inventor: Riccardo Leone Benedetti , Reto Huesser , Goran Savatic , Norbert Schmitt
Abstract: A method to localize a carrier on a laboratory transport system is presented. The laboratory transport system comprises a carrier associated with an identity, a multi-lane transport module, and a control unit. The carrier comprises a signal transmitter configured to transmit a signal comprising information about the identity. The multi-lane transport module comprises a transport surface comprising a first and a second transport lane as well as a first signal receiver and a second signal receiver each configured to receive the transmitted signal. Based on received signal strengths, the control unit localizes the carrier on one of the transport lanes of the multi-lane transport module.
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公开(公告)号:US10436685B2
公开(公告)日:2019-10-08
申请号:US15417858
申请日:2017-01-27
Applicant: Roche Diagnostics Operations, Inc.
Inventor: Claudio Cherubini , Martin Kopp , Nenad Milicevic , Daniel Mueller , Emad Sarofim , Goran Savatic
IPC: G01N1/40 , G01N15/04 , G01N35/00 , G01N35/10 , B01L3/00 , B04B11/04 , B04B13/00 , B04B5/04 , B04B7/08 , C12M1/00
Abstract: A method for processing particles contained in a liquid biological sample is presented. The method uses a rotatable vessel for processing particles contained in a liquid biological sample. The rotatable vessel has a longitudinal axis about which the vessel is rotatable, an upper portion having a top opening for receiving the liquid comprising the particles, a lower portion for holding the liquid while the rotatable vessel is resting, the lower portion having a bottom, and an intermediate portion located between the upper portion and the lower portion, the intermediate portion having a lateral collection chamber for holding the liquid while the rotatable vessel is rotating. The method employs dedicated acceleration and deceleration profiles for sedimentation and re-suspension of the particles of interest.
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公开(公告)号:US20180010990A1
公开(公告)日:2018-01-11
申请号:US15417858
申请日:2017-01-27
Applicant: Roche Diagnostics Operations, Inc.
Inventor: Claudio Cherubini , Martin Kopp , Nenad Milicevic , Daniel Mueller , Emad Sarofim , Goran Savatic
IPC: G01N1/40 , B04B5/04 , B04B7/08 , B01L3/00 , G01N35/10 , G01N35/00 , G01N15/04 , B04B13/00 , B04B11/04
CPC classification number: G01N1/4077 , B01L3/5021 , B01L2300/0848 , B01L2300/0858 , B01L2300/168 , B01L2400/086 , B04B5/0407 , B04B7/08 , B04B11/04 , B04B13/00 , C12M47/02 , G01N1/405 , G01N15/042 , G01N35/00584 , G01N35/10 , G01N2001/4083 , G01N2015/045 , Y10T436/111666 , Y10T436/25375
Abstract: A method for processing particles contained in a liquid biological sample is presented. The method uses a rotatable vessel for processing particles contained in a liquid biological sample. The rotatable vessel has a longitudinal axis about which the vessel is rotatable, an upper portion comprising a top opening for receiving the liquid comprising the particles, a lower portion for holding the liquid while the rotatable vessel is resting, the lower portion comprising a bottom, and an intermediate portion located between the upper portion and the lower portion, the intermediate portion comprising a lateral collection chamber for holding the liquid while the rotatable vessel is rotating. The method employs dedicated acceleration and deceleration profiles for sedimentation and re-suspension of the particles of interest.
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公开(公告)号:US09606140B2
公开(公告)日:2017-03-28
申请号:US14286194
申请日:2014-05-23
Applicant: Roche Diagnostics Operations, Inc.
Inventor: Geza Burghardt , Michael Glauser , Oliver Gutmann , Daniel Mueller , Edwin Oosterbroek , Roger Sandoz , Emad Sarofim , Goran Savatic
CPC classification number: G01P15/02 , B01L3/5021 , B01L3/5453 , B01L2200/14 , B01L2200/143 , B01L2300/021 , B01L2300/025 , B01L2300/0663 , B01L2400/0409
Abstract: An acceleration sensitive indicator for indicating a centrifugation status of a biological sample, a sample container comprising the indicator, a centrifuge for centrifuging samples and an analytical system for analyzing centrifuged samples are disclosed. The indicator comprises at least one closed chamber, formed between two opposite surfaces, that comprises an indication zone that comprises at least two fluid transfer zones or at least one particle transfer zone. The at least one fluid transfer zone comprises a solid carrier phase and a fluid stabilized in the solid carrier phase or at least one non-stabilized non-Newtonian fluid having thixotropic and/or shear thinning properties. The at least one particle transfer zone comprises a particle stabilizing fluid comprising stabilized dispersed particles. The fluid or particles have a distribution with respect to the indication zone changeable upon application of a g-force above a threshold value, the change of distribution indicating the centrifugation status.
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公开(公告)号:US12196772B2
公开(公告)日:2025-01-14
申请号:US17008778
申请日:2020-09-01
Applicant: Roche Diagnostics Operations, Inc.
Inventor: Riccardo Leone Benedetti , Reto Huesser , Goran Savatic , Norbert Schmitt
Abstract: A method to localize a carrier on a laboratory transport system is presented. The laboratory transport system comprises a carrier associated with an identity, a multi-lane transport module, and a control unit. The carrier comprises a signal transmitter configured to transmit a signal comprising information about the identity. The multi-lane transport module comprises a transport surface comprising a first and a second transport lane as well as a first signal receiver and a second signal receiver each configured to receive the transmitted signal. Based on received signal strengths, the control unit localizes the carrier on one of the transport lanes of the multi-lane transport module.
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公开(公告)号:US11747354B2
公开(公告)日:2023-09-05
申请号:US17211113
申请日:2021-03-24
Applicant: Roche Diagnostics Operations, Inc.
Inventor: Goran Savatic
IPC: G01N35/00
CPC classification number: G01N35/00732 , G01N35/00623 , G01N2035/00752
Abstract: The present disclosure relates to a method to re-identify a carrier on a laboratory transport system after a system failure. The carrier is associated with an identity and is configured to move over a transport plane of the laboratory transport system. The laboratory transport system comprises a monitoring system configured to monitor motion positions of the carrier on the transport plane when the laboratory transport system is activated. After a system failure, the identity dissociates from the carrier and the carrier keeps moving on the transport plane. After reactivation of the laboratory transport system, a predicted position of the identity is compared to an actual position of the carrier by a control unit of the laboratory transport system. The control unit assigns the identity to the carrier if the predicted position of the identity matches with the actual position of the carrier.
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公开(公告)号:US20210302449A1
公开(公告)日:2021-09-30
申请号:US17211113
申请日:2021-03-24
Applicant: Roche Diagnostics Operations, Inc.
Inventor: Goran Savatic
IPC: G01N35/00
Abstract: The present disclosure relates to a method to re-identify a carrier on a laboratory transport system after a system failure. The carrier is associated with an identity and is configured to move over a transport plane of the laboratory transport system. The laboratory transport system comprises a monitoring system configured to monitor motion positions of the carrier on the transport plane when the laboratory transport system is activated. After a system failure, the identity dissociates from the carrier and the carrier keeps moving on the transport plane. After reactivation of the laboratory transport system, a predicted position of the identity is compared to an actual position of the carrier by a control unit of the laboratory transport system. The control unit assigns the identity to the carrier if the predicted position of the identity matches with the actual position of the carrier.
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