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    Methods for performing dry chemistry, lateral flow-reconstituted chromatographic enzyme-driven assays
    13.
    发明授权
    Methods for performing dry chemistry, lateral flow-reconstituted chromatographic enzyme-driven assays 有权
    进行干化学，侧流重构色谱酶驱动试验的方法

    公开(公告)号：US09556472B2

    公开(公告)日：2017-01-31

    申请号：US14552626

    申请日：2014-11-25

    Applicant: Alere Scarborough, Inc.

    Inventor： Roger N. Piasio ,  Nathan Turner

    IPC: B01J20/28 ,  C12Q1/32 ,  G01N33/543 ,  G01N33/558 ,  B01J20/281 ,  G01N21/78 ,  G01N33/52

    CPC classification number: C12Q1/32 ,  B01J20/28033 ,  B01J20/281 ,  G01N21/78 ,  G01N33/523 ,  G01N33/54326 ,  G01N33/558 ,  G01N2333/902 ,  G01N2333/904 ,  G01N2333/986

    Abstract: Methods for performing dry chemistry, lateral flow-reconstituted chromatographic enzyme-driven assays are described. A combination of components necessary to elicit a specific enzyme reaction are predeposited as substrate in dry form together with ingredients necessary to produce a desired color upon occurrence of the desired reaction. The strip is equipped with a sample pad placed ahead of the substrate deposit in the flowstream, to which liquid sample is applied. The sample flows from the sample pad into the substrate zone where it immediately reconstitutes the dried ingredients while also intimately mixing with them and reacting with them at the fluid front. The fluid front moves rapidly into the final “read zone” wherein the color developed is read against predetermined color standards for the desired reaction. The assay in the format of the invention is faster and easier to perform than analogous wet chemistry assays.

    Abstract translation: 描述了进行干化学，侧流重构色谱酶驱动测定的方法。 引发特定酶反应所必需的组分的组合作为底物以干燥形式预先沉积，同时在发生所需反应时产生所需颜色所需的成分。 带材上装有样品垫，放置在流动的衬底沉积物的前面，并向其施加液体样品。 样品从样品垫流入基底区域，在那里它立即重构干燥的成分，同时与它们充分混合并在流体前面与它们反应。 流体前沿快速移动到最终的“读取区域”，其中根据预期的颜色标准读取显色的颜色用于所需的反应。 本发明形式的测定比类似的湿化学测定更快更容易进行。

    Assembly of a cartridge and a cartridge clamp, and a cartridge clamp for use in such an assembly
    19.
    发明授权
    Assembly of a cartridge and a cartridge clamp, and a cartridge clamp for use in such an assembly 有权
    盒和盒夹的组装以及用于这种组件的盒夹

    公开(公告)号：US09110072B2

    公开(公告)日：2015-08-18

    申请号：US13568671

    申请日：2012-08-07

    Applicant: Peter S. Tamminga ,  Jeroen Camstra

    Inventor： Peter S. Tamminga ,  Jeroen Camstra

    IPC: G01N30/60 ,  B01J20/281 ,  G01N30/00

    CPC classification number: G01N30/6026 ,  B01J20/281 ,  G01N30/6091 ,  G01N2030/009

    Abstract: An assembly of a cartridge and a cartridge clamp is disclosed. The cartridge has a cartridge body bounding a passage extending from a first end face to a second end face of the cartridge body. The cartridge clamp has a first and second clamping jaw comprising a first and second clamping face, respectively. A first and a second conduit are connected to the first and second clamping jaw, respectively. Said cartridge clamp is adapted for clamping said cartridge in-between the first and the second clamping face and for forming a closed circuit composed of the first conduit, the passage and the second conduit during clamping. Each clamping face has a ring-shaped protrusion extending around the end aperture of the respective conduit. The cartridge body is completely made of PEEK and each ring-shaped protrusion has a contact end face.

    Abstract translation: 公开了一种盒和盒夹的组件。 该盒具有一个盒体，该盒体限定从盒体的第一端面延伸到第二端面的通道。 盒式夹具具有分别包括第一和第二夹紧面的第一和第二夹钳。 第一和第二导管分别连接到第一和第二夹钳。 所述盒式夹具适于将所述盒夹持在第一和第二夹紧面之间，并且用于在夹紧期间形成由第一导管，通道和第二导管组成的闭合回路。 每个夹紧面具有围绕相应管道的端部孔延伸的环形突起。 盒体完全由PEEK制成，每个环形突起具有接触端面。

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