公开(公告)号：US07623225B2

公开(公告)日：2009-11-24

申请号：US12256786

申请日：2008-10-23

Applicant: Charles W. Robertson, Jr. ,  Joel B. Hansen ,  Dale Heintzelman ,  Thomas A. Tokash ,  Paul S. Zdinak ,  Damian W. Ashmead ,  Jonathan Pundt

Inventor： Charles W. Robertson, Jr. ,  Joel B. Hansen ,  Dale Heintzelman ,  Thomas A. Tokash ,  Paul S. Zdinak ,  Damian W. Ashmead ,  Jonathan Pundt

IPC: G01J1/04

CPC classification number: G01J3/02 ,  G01J3/0202 ,  G01J3/0218 ,  G01J3/0224 ,  G01J3/0235 ,  G01J3/027 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/32 ,  G01N21/6445 ,  G01N21/645 ,  G01N2021/035 ,  G01N2021/6471 ,  G01N2201/0245

Abstract: A photometer is provided with modular lighting units wherein each lighting unit includes one or more light emitters. A user may select a desired lighting unit and install it within a photometer base unit, and thereafter activate one or more of the emitters (which may emit light of different wavelengths) to illuminate a specimen. The light provided by the specimen in response can then be captured at a detector, and analyzed to provide an indication of the specimen's characteristics. Different lighting units may optionally include one or more input light adapters (filters or polarizers which modify the light provided by the emitter(s) to the specimen), and/or one or more output light adapters (filters or polarizers which modify the light provided by the specimen to the detector). Users may therefore select lighting units with emitters and light adapters which are particularly suited for detection/analysis of particular specimens and/or components therein.

Abstract translation: 光度计设置有模块化照明单元，其中每个照明单元包括一个或多个发光器。 用户可以选择所需的照明单元并将其安装在光度计基座单元内，然后激活一个或多个发射器（其可以发射不同波长的光）以照射样本。 然后可以在检测器处捕获由样品提供的光，并分析以提供样品特征的指示。 不同的照明单元可以可选地包括一个或多个输入光适配器（将由发射器提供的光修改为样本的滤光器或偏振器）和/或一个或多个输出光适配器（改变所提供的光的滤光器或偏振器 通过样品到检测器）。 因此，用户可以选择具有发射器和光适配器的照明单元，其特别适于检测/分析其中的特定样品和/或部件。

公开(公告)号：US20090091759A1

公开(公告)日：2009-04-09

申请号：US11867956

申请日：2007-10-05

Applicant: Jing Jong Pan ,  Zhengda Pang ,  Yonghong Guo

Inventor： Jing Jong Pan ,  Zhengda Pang ,  Yonghong Guo

IPC: G01J3/51

CPC classification number: G01J9/00 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0235

Abstract: A device and method of operation for analyzing signal features over multiple optical wavelengths is presented. A plurality of rotating thin film filters is arranged with respect to a collimated beam of light so that each thin film filter transmits light of a particular wavelength to a detector unit responsive to an angle of incidence of light upon the thin film filter when the thin film filter optically interposes the collimated light beam. Each of the plurality of thin film filters is optically interposed periodically and rotated so that the angle of incidence of light from the first input unit upon the thin film filter varies when the thin film filter is optically interposed to scan the light by wavelength within a selected wavelength band into a detector unit for measurement.

Abstract translation: 提出了一种用于分析多个光波长的信号特征的装置和操作方法。 相对于准直光束布置多个旋转薄膜滤光器，使得每个薄膜滤光器响应于薄膜滤光片上的光入射角而将特定波长的光透射到检测器单元，当薄膜 滤光片光学地插入准直光束。 多个薄膜滤光器中的每一个周期性地被光学地插入并旋转，使得当薄膜滤光器被光学插入时，来自第一输入单元的薄膜滤光器的入射角度变化，以便在选定的 波长带进入检测器单元进行测量。

公开(公告)号：US20090068747A1

公开(公告)日：2009-03-12

申请号：US12033711

申请日：2008-02-19

Applicant: Roger Iten

Inventor： Roger Iten

IPC: G01N23/00 ,  C12M1/34

CPC classification number: G01N21/6452 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0235 ,  G01J3/10 ,  G01J3/32 ,  G01N2021/6471 ,  G01N2021/6484 ,  G01N2201/0627

Abstract: Subject of the present invention is to provide an apparatus, an instrument, and a method particularly useful in multiplex PCR applications permitting short sample measuring times of many samples combined with high sensitivity.

Abstract translation: 本发明的主题是提供一种在多重PCR应用中特别有用的装置，仪器和方法，其允许许多样品与较高灵敏度组合的样品测量时间较短。

公开(公告)号：US20080259428A1

公开(公告)日：2008-10-23

申请号：US11576215

申请日：2005-09-30

Applicant: David A. Zimdars ,  Artur Chernovsky ,  Steven L. Williamson ,  Klaus Wolter

Inventor： David A. Zimdars ,  Artur Chernovsky ,  Steven L. Williamson ,  Klaus Wolter

IPC: G02B26/06

CPC classification number: G02B26/06 ,  G01J3/0205 ,  G01J3/0235 ,  G02B5/122

Abstract: An optical delay line device includes a rotatable wheel and one or more prisms mounted about the circumference of the wheel. The one are more prisms are positioned to retroreflect the optical beam that passes approximately tangent to the wheel to cause a delay or phase shift to the beam as the wheel rotates.

Abstract translation: 光学延迟线装置包括可旋转轮和围绕车轮圆周安装的一个或多个棱镜。 一个更多的棱镜被定位成回射近似于切向轮的光束，以在轮转动时造成延迟或相移到光束。

公开(公告)号：US07321424B2

公开(公告)日：2008-01-22

申请号：US11197195

申请日：2005-08-04

Applicant: James A. McCandless

Inventor： James A. McCandless

IPC: G01J3/42

CPC classification number: G01J3/02 ,  G01B11/0616 ,  G01J1/18 ,  G01J3/021 ,  G01J3/0229 ,  G01J3/0235 ,  G01J3/06 ,  G01J3/28 ,  G01J3/42 ,  G01J2003/2866 ,  G01N21/251 ,  G01N21/276 ,  G01N21/55 ,  G01N21/59 ,  G01N2201/12723 ,  G01N2201/128 ,  G01N2201/1281

Abstract: In a self-referencing instrument for measuring electromagnetic radiation, a mounting member to which a sample can be coupled moves the sample such that, in a first position, the electromagnetic radiation impinges on the sample, and, in a second position, the electromagnetic radiation does not impinge on the sample. A detection unit receives the electromagnetic radiation from the sample and generates a sample signal when the sample is in the first position, and the detection unit receives the electromagnetic radiation from the source and generates a reference signal when the sample is in the second position. A processor coupled to the detection unit processes the reference signal and the sample signal. This results in a continuous, accurate reference measurement, and permits the instrument to efficiently compensate for error, while offering accurate measurements.

Abstract translation: 在用于测量电磁辐射的自参考仪器中，可以耦合样品的安装构件移动样品，使得在第一位置，电磁辐射照射在样品上，并且在第二位置中，电磁辐射 不会影响样品。 检测单元从样本接收电磁辐射，并且当样本处于第一位置时产生采样信号，并且当样本处于第二位置时，检测单元从源接收电磁辐射并产生参考信号。 耦合到检测单元的处理器处理参考信号和采样信号。 这将产生连续，准确的参考测量，并允许仪器有效地补偿误差，同时提供准确的测量。

公开(公告)号：US07315377B2

公开(公告)日：2008-01-01

申请号：US10544421

申请日：2004-02-10

Applicant: Stephen Keith Holland ,  Roland H. Krauss ,  James M. Childers, IV ,  Gabriel Laufer

Inventor： Stephen Keith Holland ,  Roland H. Krauss ,  James M. Childers, IV ,  Gabriel Laufer

IPC: G01J3/51 ,  G01N21/25

CPC classification number: G01J3/02 ,  G01J3/021 ,  G01J3/0229 ,  G01J3/0235 ,  G01J3/2803 ,  G01J3/32 ,  G01J3/36 ,  G01J2001/4242 ,  G01N21/31 ,  G01N21/3518 ,  G01N2021/1793 ,  G01N2021/3137 ,  G01N2021/317 ,  G01N2021/3531

Abstract: A method and a low-cost, robust and simple system for remote sensing and analyzing spectral properties of targets as a means to detect and identify them is introduced. The system can be highly portable but is usable in fixed locations or combination thereof. An aspect of the method and system includes the capability to distribute, modulate, aperture and spectrally analyze radiation emitted or absorbed by a volumetric target chemical species (solid, liquid or gas) or a target surface. Radiation is first collected by a single light gathering device, such as a lens, telescope, or mirror, and then distributed to multiple detectors through spectrally discriminating components and if desired through apertures to achieve this desired detection and identification.

Abstract translation: 介绍了一种用于遥感和分析目标光谱属性的方法和低成本，稳健和简单的系统，作为检测和识别目标的手段。 该系统可以高度便携，但是可以在固定位置或其组合中使用。 该方法和系统的一个方面包括分布，调制，孔径和光谱分析由体积目标化学物质（固体，液体或气体）或目标表面发射或吸收的辐射的能力。 辐射首先由单一的聚光装置如透镜，望远镜或反射镜收集，然后通过光谱鉴别部件分布到多个检测器，并且如果需要，通过孔径分布以实现所需的检测和识别。

公开(公告)号：US07253894B2

公开(公告)日：2007-08-07

申请号：US11053263

申请日：2005-02-07

Applicant: Haishan Zeng ,  Stephen Lam ,  Branko Mihael Palcic

Inventor： Haishan Zeng ,  Stephen Lam ,  Branko Mihael Palcic

IPC: G01J3/28

CPC classification number: G01J3/02 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/0235 ,  G01J3/0243 ,  G01J3/0289 ,  G01J3/10 ,  G01J3/36 ,  G01N23/223 ,  G01N2223/076

Abstract: Optical systems that provide for simultaneous images and spectra from an object, such as a tissue sample, an industrial object such as a computer chip, or any other object that can be viewed with an optical system such as a microscope, endoscope, telescope or camera. In some embodiments, the systems provide multiple images corresponding to various desired wavelength ranges within an original image of the object, as well as, if desired, directional pointer(s) that can provide both an identification of the precise location from which a spectrum is being obtained, as well as enhancing the ability to point the device.

Abstract translation: 提供来自物体的同时图像和光谱的光学系统，例如组织样本，诸如计算机芯片的工业对象或可以用诸如显微镜，内窥镜，望远镜或照相机的光学系统观察的任何其它物体 。 在一些实施例中，系统提供对应于对象的原始图像内的各种期望波长范围的多个图像，以及如果需要的方向指针，其可以提供频谱的精确位置的识别 获得，以及增强指向设备的能力。

公开(公告)号：US20070019295A1

公开(公告)日：2007-01-25

申请号：US11485163

申请日：2006-07-12

Applicant: Andreas Mitreiter ,  Clemens Hanschke

Inventor： Andreas Mitreiter ,  Clemens Hanschke

IPC: G02B5/18 ,  G02B27/44

CPC classification number: G01J3/1804 ,  G01J3/02 ,  G01J3/0235 ,  G01J3/0262 ,  G01J3/04 ,  G01J3/42 ,  G02B5/18 ,  G02B27/4244

Abstract: The invention concerns a circular disk-shaped carrier system with a plurality of integrated diffraction structures for the spectral analysis of light of the wavelengths 340-800 nm, wherein each diffraction structure includes a layer of a transparent plastic material which has a microstructure suitable for the diffraction of a wavelength within the wavelength spectrum of the light, and the carrier system includes at least two diffraction structures for the diffraction of light of differing wavelength.

Abstract translation: 本发明涉及具有多个集成的衍射结构的圆盘形载体系统，用于波长为340-800nm的光的光谱分析，其中每个衍射结构包括透明塑料材料层，其具有适合于 在光的波长光谱内的波长的衍射，并且载体系统包括用于不同波长的光的衍射的至少两个衍射结构。

公开(公告)号：US07119902B2

公开(公告)日：2006-10-10

申请号：US11215992

申请日：2005-08-30

Applicant: Matt Beaumont

Inventor： Matt Beaumont

IPC: G01N21/25

CPC classification number: G02B5/20 ,  G01J3/02 ,  G01J3/0235 ,  G01J3/12 ,  G01J3/28 ,  G01N21/274 ,  G02B26/008

Abstract: Calibrating each of a plurality of driven optical filters. The color parameters of the driven optical filters are characterized for the individual optical filter. These color parameters are used as calibration data to calibrate more standard information.

公开(公告)号：US07115841B2

公开(公告)日：2006-10-03

申请号：US11057965

申请日：2005-02-14

Applicant: Haishan Zeng ,  Stephen Lam ,  Branko Mihael Palcic

Inventor： Haishan Zeng ,  Stephen Lam ,  Branko Mihael Palcic

IPC: H05B3/02

CPC classification number: G01J3/02 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/0235 ,  G01J3/0243 ,  G01J3/0289 ,  G01J3/10 ,  G01J3/36 ,  G01N23/223 ,  G01N2223/076

Abstract: Optical systems that provide for simultaneous images and spectra from an object, such as a tissue sample, an industrial object such as a computer chip, or any other object that can be viewed with an optical system such as a microscope, endoscope, telescope or camera. In some embodiments, the systems provide multiple images corresponding to various desired wavelength ranges within an original image of the object, as well as, if desired, directional pointer(s) that can provide both an identification of the precise location from which a spectrum is being obtained, as well as enhancing the ability to point the device.

Abstract translation: 提供来自物体的同时图像和光谱的光学系统，例如组织样本，诸如计算机芯片的工业对象或可以用诸如显微镜，内窥镜，望远镜或照相机的光学系统观察的任何其它物体 。 在一些实施例中，系统提供对应于对象的原始图像内的各种期望波长范围的多个图像，以及如果需要的方向指针，其可以提供频谱的精确位置的识别 获得，以及增强指向设备的能力。