公开(公告)号：US20150204798A1

公开(公告)日：2015-07-23

申请号：US14629527

申请日：2015-02-24

Applicant: GII ACQUISITION, LLC dba GENERAL INSPECTION, LLC

Inventor： Michael G. Nygaard ,  Nathan Andrew-Paul Kujacznski

IPC: G01N21/95 ,  G01N21/952 ,  G01B11/00

CPC classification number: H04N13/254 ,  B07C5/342 ,  F42B35/00 ,  G01B11/2433 ,  G01N21/909 ,  G01N21/9515 ,  G01N21/952 ,  G01N2201/02 ,  G01N2201/0224 ,  G01N2201/0621 ,  G01N2201/0638 ,  G01N2201/12 ,  G06K9/6202

Abstract: A method and system for inspecting a manufactured part at an inspection station are provided. A supported part is rotated about a measurement axis so that the part moves at predetermined angular increments during at least one rotational scan. A backside beam of collimated radiation is directed at and is occluded by the supported part at each of a first plurality of consecutive increments of movement to create a stream of unobstructed portions of the backside beam in rapid succession passing by and not blocked by the supported part. A frontside beam of radiation is directed at and is reflected by the supported part at each of a second plurality of consecutive increments of movement to create a stream of reflected portions of the frontside beam in rapid succession. The streams of reflected and unobstructed portions are detected at the inspection station to obtain electrical signals which are processed.

Abstract translation: 提供了一种在检查站检查制造部件的方法和系统。 支撑部件围绕测量轴线旋转，使得部件在至少一次旋转扫描期间以预定的角度增量移动。 准直辐射的后侧光束被引导并被第一多个连续运动增量中的每一个被被支撑部分遮挡，以产生快速连续地通过并未被被支撑部分阻挡的背侧光束的无障碍部分的流 。 在第二多个连续运动增量中的每一个上，前方束的辐射被引导并被所支撑的部分反射，从而快速连续地产生前侧梁的反射部分的流。 在检查站检测反射和无障碍部分的流，以获得被处理的电信号。

公开(公告)号：US20150204791A1

公开(公告)日：2015-07-23

申请号：US14251838

申请日：2014-04-14

Applicant: Tsinghua University ,  HON HAI PRECISION INDUSTRY CO., LTD.

Inventor： ZHEN-DONG ZHU ,  QUN-QING LI ,  BEN-FENG BAI ,  SHOU-SHAN FAN

IPC: G01N21/65 ,  G01N21/01

CPC classification number: G01N21/658 ,  G01N21/01 ,  G01N2201/02

Abstract: A Raman detecting system includes a bowl shaped metal nanostructure array configured to load a sample, a projecting module configured to project a beam of light to the bowl shaped metal nanostructure array, and a receiving module configured to collect the light scattered by the bowl shaped metal nanostructure array. The bowl shaped metal nanostructure array includes a substrate having a surface and a number of particle-in-bowl structures located on the surface of the substrate. Each particle-in-bowl structure includes a bowl shaped concave structure and a protruding member protruding from the bowl shaped concave structure. The protruding member is integrated with the bowl shaped concave structure.

Abstract translation: 一种拉曼检测系统，包括：构造成装载样品的碗形金属纳米结构阵列;配置成将光束投射到碗形金属纳米结构阵列的投影模块;以及接收模块，其被配置为收集由碗状金属 纳米结构阵列。 碗形金属纳米结构阵列包括具有位于基底表面上的表面和多个颗粒在碗结构的基底。 每个碗内碗形结构包括碗形凹形结构和从碗状凹形结构突出的突出构件。 突出部件与碗形凹形结构集成。

公开(公告)号：US20150198527A1

公开(公告)日：2015-07-16

申请号：US14668562

申请日：2015-03-25

Applicant: Murata Manufacturing Co., Ltd.

Inventor： Takashi Kondo ,  Seiji Kamba ,  Tetsuzo Hara ,  Masayuki Suzuki

IPC: G01N21/59 ,  G02B5/18 ,  G01N21/01

CPC classification number: G01N21/59 ,  G01N21/01 ,  G01N21/03 ,  G01N21/3581 ,  G01N2021/0339 ,  G01N2201/02 ,  G01N2201/061 ,  G02B5/18 ,  G02B21/34 ,  H01J37/20 ,  H01J37/3178 ,  Y10T29/49

Abstract: A perforated-structure body having a plurality of apertures that penetrate from a first main surface to a second main surface of a perforated plate. Support substrates are stacked on at least one of the first main surface and the second main surface of the perforated plate so as to define a portion through which at least one of the apertures is exposed.

Abstract translation: 一种穿孔结构体，具有从多孔板的第一主表面到第二主表面穿透的多个孔。 支撑基板被堆叠在多孔板的第一主表面和第二主表面中的至少一个上，以便限定出露出至少一个孔的部分。

公开(公告)号：US20150185137A1

公开(公告)日：2015-07-02

申请号：US14579085

申请日：2014-12-22

Applicant: NICHIA CORPORATION

Inventor： Koichi AMARI

IPC: G01N21/25 ,  H01L33/50 ,  G01N21/88 ,  H01L33/62 ,  H05K1/02 ,  H05K1/03 ,  H01L33/48 ,  H01L33/54

CPC classification number: G01N21/25 ,  G01N21/8806 ,  G01N2201/02 ,  G01N2201/062 ,  H01L25/0753 ,  H01L33/486 ,  H01L33/50 ,  H01L33/54 ,  H01L33/62 ,  H01L2224/16225 ,  H01L2924/0002 ,  H01L2933/0041 ,  H01L2933/0066 ,  H01L2924/00

Abstract: An aggregate board, comprising: an insulator having a front face and a rear face; a pair of a first front face wiring pattern and a second front face wiring pattern, a plurality of which are arranged on the front face of the insulator; a pair of a first rear face wiring pattern and a second rear face wiring pattern, a plurality of which are arranged on the rear face of the insulator; at least one first inner layer wiring pattern that is separated from the second front face wiring pattern and the second rear face wiring pattern, that is connected to the first front face wiring pattern and the first rear face wiring pattern, and that extends in a first direction in an interior of the insulator; at least one second inner layer wiring pattern that is separated from the first front face wiring pattern and the first rear face wiring pattern, that is connected to the second front face wiring pattern and the second rear face wiring pattern, and that has a part that extends in a second direction which is different from the first direction, in the interior of the insulator; and the first inner layer wiring pattern and the second inner layer wiring pattern being positioned in the same layer.

Abstract translation: 一种聚集板，包括：具有前表面和后表面的绝缘体; 一对第一前面布线图案和第二前面布线图案，其多个布置在绝缘体的正面上; 一对第一背面布线图案和第二背面布线图案，多个布置在绝缘体的背面上; 至少一个第一内层布线图案，其与第二正面布线图案和第二背面布线图案分离，该第一内层布线图案与第一正面布线图案和第一背面布线图案相连， 绝缘体内部的方向; 与第一前面布线图案和第一背面布线图案分离的至少一个第二内层布线图案，其连接到第二正面布线图案和第二后面布线图案，并且具有 在绝缘体的内部沿与第一方向不同的第二方向延伸; 并且第一内层布线图案和第二内层布线图案位于同一层中。

公开(公告)号：US20150177150A1

公开(公告)日：2015-06-25

申请号：US14543867

申请日：2014-11-17

Applicant: Quantum-Si Incorporated

Inventor： Jonathan M. Rothberg ,  Ali Kabiri ,  Jason W. Sickler ,  Brett J. Gyarfas ,  Jeremy Lackey ,  Gerard Schmid ,  Benjamin Cipriany ,  Jack Jewell ,  Lawrence West ,  Michael Ferrigno ,  Paul E. Glenn ,  Adam E. Cohen ,  Anthony Bellofiore

IPC: G01N21/64

CPC classification number: G01N21/6486 ,  B01L3/5085 ,  B01L2200/12 ,  B01L2300/0829 ,  B01L2300/0887 ,  B01L2300/0893 ,  B01L2300/168 ,  C12Q1/6869 ,  C12Q1/6874 ,  C12Q2521/101 ,  C12Q2537/157 ,  C12Q2563/107 ,  C12Q2565/607 ,  G01N21/64 ,  G01N21/645 ,  G01N21/6452 ,  G01N21/648 ,  G01N21/7743 ,  G01N21/7746 ,  G01N2021/6419 ,  G01N2021/6441 ,  G01N2021/6478 ,  G01N2201/02 ,  G01N2201/06113 ,  G01N2201/0612 ,  G01N2201/062 ,  G01N2201/068 ,  G01N2201/125 ,  Y10T29/49016 ,  C12Q2525/101

Abstract: Apparatus and methods for analyzing single molecule and performing nucleic acid sequencing. An apparatus can include an assay chip that includes multiple pixels with sample wells configured to receive a sample, which, when excited, emits emission energy; at least one element for directing the emission energy in a particular direction; and a light path along which the emission energy travels from the sample well toward a sensor. The apparatus also includes an instrument that interfaces with the assay chip. The instrument includes an excitation light source for exciting the sample in each sample well; a plurality of sensors corresponding the sample wells. Each sensor may detect emission energy from a sample in a respective sample well. The instrument includes at least one optical element that directs the emission energy from each sample well towards a respective sensor of the plurality of sensors.

Abstract translation: 用于分析单分子和进行核酸测序的装置和方法。 装置可以包括测定芯片，其包括多个像素，其中样品阱被配置为接收样品，当被激发时，样品阱发射发射能量; 用于在特定方向上引导发射能量的至少一个元件; 以及发光能量从样品阱向传感器行进的光路。 该装置还包括与测定芯片接口的仪器。 仪器包括用于激发每个样品井中的样品的激发光源; 多个传感器对应于样品孔。 每个传感器可以检测来自相应样品阱中的样品的发射能量。 仪器包括至少一个光学元件，其将来自每个样品的发射能量引向多个传感器中的相应传感器。

公开(公告)号：US20150165435A1

公开(公告)日：2015-06-18

申请号：US14405659

申请日：2013-06-05

Applicant: INSTITUTO DE ENGENHARIA DE SISTEMAS E COMPUTADORES PARA OS MICROSISTEMAS E AS NANOTECNOLOGIAS...

Inventor： Virginia Chu ,  Pedro José De Oliva Novo ,  João Pedro Estrela Rodrigues Conde ,  Francesca Volpetti

IPC: B01L3/00 ,  G01N21/25 ,  G01N21/64 ,  G01N21/76

CPC classification number: B01L3/5027 ,  B01L3/502715 ,  B01L3/502784 ,  B01L2200/0621 ,  B01L2200/0642 ,  B01L2200/0673 ,  B01L2400/0406 ,  G01N21/251 ,  G01N21/6486 ,  G01N21/76 ,  G01N2201/02 ,  G01N2201/061 ,  Y10T436/2575

Abstract: Aspects of the present disclosure relate to a capillary fluidic device comprising at least two inlets, a microfluidic channel and an outlet. The device allows for the autonomous and programmable sequential flow of the same or different fluids using capillary fluidics for autonomous pumping of liquids to other downstream fluidic structures. External pumping and valving systems are not required, thus reducing complexity and increasing portability of stand-alone microfluidic systems. Aspects of the present disclosure can be applied to other fluidic structures for performing analytical biological assays. The integration has at least one reaction chamber and at least one capillary pump. The device is integrated with at least one sensor for detection and quantification of the biological assay signals.

Abstract translation: 本公开的方面涉及包括至少两个入口，微流体通道和出口的毛细管流体装置。 该装置允许使用毛细管流体自动泵送液体到其它下游流体结构的相同或不同流体的自主和可编程顺序流动。 不需要外部泵送和阀门系统，因此降低了独立微流体系统的复杂性和增加的便携性。 本公开的方面可以应用于用于进行分析生物测定的其它流体结构。 整合具有至少一个反应室和至少一个毛细管泵。 该装置与至少一个传感器集成，用于检测和定量生物测定信号。

公开(公告)号：US20150160252A1

公开(公告)日：2015-06-11

申请号：US14559647

申请日：2014-12-03

Applicant: CANON KABUSHIKI KAISHA

Inventor： Yoichi Murakami

IPC: G01N35/10 ,  G01N21/76 ,  G01N21/11 ,  G01F23/292

CPC classification number: G01N35/1016 ,  G01F23/284 ,  G01F23/292 ,  G01N35/1011 ,  G01N2035/1025 ,  G01N2201/02 ,  G01N2201/061

Abstract: A method of measuring a position of a liquid surface in a light transmissive container, includes: irradiating a liquid surface with light obliquely so the light is transmitted through an inner wall that comes into contact with liquid and is totally reflected from an inner wall that comes into contact with air in the state in which a light-receiving surface is present on a bottom portion of the container; and detecting a position of a boundary between a dark portion and a bright portion generated by the total reflection on the light-receiving surface.

Abstract translation: 一种测量透光容器中的液面的位置的方法，包括：使光倾斜地照射液面，使得光透过与液体接触的内壁，并从内壁全反射 在容器的底部存在受光面的状态下与空气接触; 以及检测由受光面上的全反射产生的暗部与亮部之间的边界的位置。

公开(公告)号：US20150157249A1

公开(公告)日：2015-06-11

申请号：US14598111

申请日：2015-01-15

Applicant: OptiScan Biomedical Corporation

Inventor： Jennifer H. Gable ,  James R. Braig ,  Kenneth I. Li ,  Mark Wechsler ,  Peng Zheng ,  Richard Keenan

IPC: A61B5/157 ,  A61B5/15 ,  G01N21/3577

CPC classification number: A61B5/157 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/0086 ,  A61B5/1411 ,  A61B5/1427 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14535 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/15003 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150267 ,  A61B5/150358 ,  A61B5/150755 ,  A61B5/150862 ,  A61B5/150992 ,  A61B5/153 ,  A61B5/155 ,  A61B5/4839 ,  A61B10/0064 ,  A61B2560/0443 ,  A61M5/14212 ,  A61M5/14232 ,  A61M5/16854 ,  A61M5/1723 ,  A61M5/365 ,  A61M5/38 ,  A61M2205/12 ,  A61M2205/3306 ,  A61M2230/20 ,  A61M2230/201 ,  G01N21/03 ,  G01N21/3577 ,  G01N2021/3595 ,  G01N2201/02 ,  G01N2201/061 ,  G06F19/00 ,  Y10T137/4478 ,  Y10T137/7722 ,  Y10T137/86485 ,  Y10T436/111666 ,  Y10T436/2575

Abstract: Disclosed is an apparatus for analyzing the composition of bodily fluid. The apparatus can include a fluid handling network including a patient end configured to maintain fluid communication with a bodily fluid in a patient and a pump unit in operative engagement with the fluid handling network. The pump unit can have an infusion mode, in which the pump unit is operable to deliver infusion fluid to the patient through the patient end, and a sample draw mode, in which the pump unit is operable to draw a sample of the bodily fluid from the patient through the patient end. The apparatus can include a spectroscopic analyzer positioned to analyze at least a portion of the sample; a processor in communication with or incorporated into the spectroscopic analyzer; and stored program instructions executable by the processor to obtain measurements of two or more properties of the sample.

Abstract translation: 公开了一种用于分析体液组成的装置。 该装置可以包括流体处理网络，其包括被配置为保持与患者体内的体液的流体连通的患者端和与流体处理网络可操作地接合的泵单元。 泵单元可以具有输注模式，其中泵单元可操作以通过患者端向患者输送输注流体，以及抽样模式，其中，泵单元可操作以从体外抽取体液样本 患者通过病人结束。 该装置可以包括定位成分析样品的至少一部分的光谱分析仪; 与光谱分析仪通信或并入其中的处理器; 以及可由处理器执行的存储的程序指令，以获得样本的两个或多个属性的测量。

公开(公告)号：US20150146198A1

公开(公告)日：2015-05-28

申请号：US14412774

申请日：2013-06-28

Applicant: SNECMA

Inventor： Josiane Milliot ,  Yves Chucherko ,  Jean-Michel Philippe

IPC: G01N21/91 ,  B05B13/02 ,  B05B15/04 ,  G01M15/14

CPC classification number: G01N21/91 ,  B05B1/202 ,  B05B9/007 ,  B05B13/0221 ,  B05B13/0627 ,  B05B13/0645 ,  B05B13/0672 ,  B05B14/00 ,  B05B15/25 ,  B05C7/02 ,  B05C7/04 ,  B05C11/10 ,  B62B3/08 ,  B62B2203/07 ,  F01D21/003 ,  F05D2260/80 ,  G01M15/14 ,  G01N2201/02

Abstract: A device for spraying a liquid for use in dye penetration inspection into an inner cavity of a workpiece for making a turbine engine part, the device including a workpiece support, a manifold for spraying the inspection liquid into the inner cavity, a manifold for sucking up and discharging the sprayed inspection liquid, and a mechanism for tilting at least a portion of the support from a substantially horizontal position to an inclined position in which the workpiece is inclined so that the inspection liquid sprayed into the cavity flows under gravity to a zone from which it is sucked up.

Abstract translation: 一种用于将用于染料渗透检查的液体喷射到用于制造涡轮引擎部件的工件的内腔中的装置，所述装置包括工件支撑件，用于将检查液体喷射到内腔中的歧管，用于吸入的歧管 并且喷射的检查液体的排放，以及用于将至少一部分支撑件从大致水平位置倾斜到倾斜位置的机构，在该倾斜位置，工件倾斜，使得喷射到空腔中的检查液体在重力作用下流动到从 它被吸了。

公开(公告)号：US20150141268A1

公开(公告)日：2015-05-21

申请号：US14543888

申请日：2014-11-17

Applicant: Quantum-Si Incorporated

Inventor： Jonathan M. Rothberg ,  Ali Kabiri ,  Jason W. Sickler ,  Brett J. Gyarfas ,  Jeremy Lackey ,  Gerard Schmid

IPC: C12Q1/68 ,  G01N21/64

CPC classification number: G01N21/6486 ,  B01L3/5085 ,  B01L2200/12 ,  B01L2300/0829 ,  B01L2300/0887 ,  B01L2300/0893 ,  B01L2300/168 ,  C12Q1/6869 ,  C12Q1/6874 ,  C12Q2521/101 ,  C12Q2537/157 ,  C12Q2563/107 ,  C12Q2565/607 ,  G01N21/64 ,  G01N21/645 ,  G01N21/6452 ,  G01N21/648 ,  G01N21/7743 ,  G01N21/7746 ,  G01N2021/6419 ,  G01N2021/6441 ,  G01N2021/6478 ,  G01N2201/02 ,  G01N2201/06113 ,  G01N2201/0612 ,  G01N2201/062 ,  G01N2201/068 ,  G01N2201/125 ,  Y10T29/49016 ,  C12Q2525/101

Abstract: An active-source-pixel, integrated device capable of performing biomolecule detection and/or analysis, such as single-molecule nucleic acid sequencing, is described. An active pixel of the integrated device includes a sample well into which a sample to be analyzed may diffuse, an excitation source for providing excitation energy to the sample well, and a sensor configured to detect emission from the sample. The sensor may comprise two or more segments that produce a set of signals that are analyzed to differentiate between and identify tags that are attached to, or associated with, the sample. Tag differentiation may be spectral and/or temporal based. Identification of the tags may be used to detect, analyze, and/or sequence the biomolecule.

Abstract translation: 描述了能够进行生物分子检测和/或分析的活性源像素集成器件，例如单分子核酸测序。 集成器件的有源像素包括样本阱，待分析的样本可以扩散到其中，用于向样本阱提供激发能量的激发源以及被配置为检测来自样本的发射的传感器。 传感器可以包括产生一组信号的两个或更多个片段，所述一组信号被分析以区分和识别附加到样本或与样本相关联的标签。 标签分化可以是基于频谱和/或时间的。 标签的识别可用于检测，分析和/或序列生物分子。