公开(公告)号：US20240248580A1

公开(公告)日：2024-07-25

申请号：US18099166

申请日：2023-01-19

Applicant: AGILENT TECHNOLOGIES, INC.

Inventor： Rainer JAEGER

IPC: G06F3/0482 ,  G06F3/04845

CPC classification number: G06F3/0482 ,  G06F3/04845

Abstract: In some examples, linear and non-linear range-based plot pane selection may include receiving data that is to be displayed. Based on an increase or a decrease in a size of a range selector, a selection of a range of plot panes may be received from a plurality of available plot panes to display the data. Based on the received selection of the range of plot panes, a display of the data may be generated in plot panes included in the range of plot panes. The size of the range selector may be non-linearly proportional to the available plot panes to display the data.

公开(公告)号：US20240209422A1

公开(公告)日：2024-06-27

申请号：US18423678

申请日：2024-01-26

Applicant: Agilent Technologies, Inc.

Inventor： Steen Hauge Matthiesen

IPC: C12Q1/6832 ,  C12Q1/6841 ,  C12Q1/6876

CPC classification number: C12Q1/6832 ,  C12Q1/6841 ,  C12Q1/6876

Abstract: The invention provides methods and compositions for hybridizing at least one molecule to a target. The composition comprises at least one nucleic acid sequence, formamide, and a hybridization solution, wherein the concentration of formamide is less than or equal to 25%.

公开(公告)号：US20240201143A1

公开(公告)日：2024-06-20

申请号：US18430447

申请日：2024-02-01

Applicant: Agilent Technologies, Inc.

Inventor： Thomas Ortmann ,  Martin Seifried ,  Sam Wouters ,  Irina Spuling

IPC: G01N30/20 ,  G01N30/02 ,  G01N30/14 ,  G01N30/32

CPC classification number: G01N30/20 ,  G01N30/14 ,  G01N30/32 ,  G01N2030/027 ,  G01N2030/326

Abstract: A sample separation device includes a separation path and a control unit. The separation path is between a fluid drive and a sample separation unit, and is configured to inject a fluidic sample in an injector path into a mobile phase in the separation path driven by the fluid drive to the sample separation unit for chromatographically separating the fluidic sample. The control unit is configured to control blocking the injector path or at least a partial path thereof, generating an overpressure in the blocked injector path or the partial path thereof by a pressure source, and subsequently fluidically coupling the injector path or the partial path thereof to a region of lower pressure than the overpressure to generate an expansion stroke for releasing unwanted components from the injector path.

公开(公告)号：US12015320B2

公开(公告)日：2024-06-18

申请号：US16869459

申请日：2020-05-07

Applicant: Agilent Technologies, Inc.

Inventor： Ronald J. Forni

IPC: H02K49/10 ,  F04C15/00 ,  F04C18/02 ,  F04C27/00 ,  H02K7/10

CPC classification number: H02K49/108 ,  F04C15/0069 ,  H02K7/10 ,  H02K49/104 ,  F04C18/0215 ,  F04C27/005 ,  F05C2225/00

Abstract: A magnetic coupling assembly includes a first balancing magnet positioned and surrounding drive magnets and, across a gap, a second balancing magnet and surrounding driven magnets. The drive magnets when rotated drive the driven magnets to rotate. The balancing magnets generate a repulsive force, which counterbalances an attractive force generated by the drive magnets and driven magnets. The assembly may be utilized in a pump for contactless coupling of a motor shaft to a pump shaft. The driven side of the assembly may be hermetically sealed, such as with a liquid crystal polymer boundary interposed in the gap.

公开(公告)号：US11992518B2

公开(公告)日：2024-05-28

申请号：US16455224

申请日：2019-06-27

Applicant: AGILENT TECHNOLOGIES, INC.

Inventor： Jørgen Schøller ,  Henrik Pedersen ,  Liselotte Brix

IPC: A61K39/12 ,  A61K39/00 ,  A61K39/21 ,  A61K47/61 ,  A61K47/64 ,  C07K14/74 ,  A61K38/00

CPC classification number: A61K39/00 ,  A61K39/12 ,  A61K39/21 ,  A61K47/61 ,  A61K47/646 ,  C07K14/70539 ,  A61K38/00 ,  A61K2039/5154 ,  A61K2039/54 ,  A61K2039/545 ,  A61K2039/55505 ,  A61K2039/55516 ,  A61K2039/55583 ,  A61K2039/6087 ,  A61K2039/625 ,  C12N2740/16134 ,  C12N2740/16234 ,  Y02A50/30

Abstract: The present invention relates to methods for construction of pharmamers i.e. vaccine components characterized by their multimerization domain and the attached biologically active molecules, and their use in preparation of vaccines that contains the pharmamers alone or in combination with other molecules. The individual molecules of the construct can be bound to each other or the multimerization domain(s) by covalent or non-covalent bonds, directly or via linkers. The invention further relates to the use of such preparations in vaccine settings aimed to function as preventive/prophylactic or therapeutic vaccines in humans and animals.

公开(公告)号：US20240133412A1

公开(公告)日：2024-04-25

申请号：US17969584

申请日：2022-10-18

Applicant: AGILENT TECHNOLOGIES, INC.

Inventor： Manuel VAN VENROOY ,  Patrick MATZ ,  Alan NORMAN

IPC: F16B21/06 ,  F16B21/04

CPC classification number: F16B21/065 ,  F16B21/04 ,  F16B2200/406

Abstract: In some examples, a vessel mounting system may include a first collar and a second collar. The second collar may include a clip engageable with an edge of the first collar to engage the second collar with the first collar.

公开(公告)号：US11964874B2

公开(公告)日：2024-04-23

申请号：US17234352

申请日：2021-04-19

Applicant: AGILENT TECHNOLOGIES, INC.

Inventor： Ta-Chen Wei

IPC: B01J20/28 ,  C01B33/18 ,  C09C1/30

CPC classification number: C01B33/18 ,  B01J20/28016 ,  B01J20/28021 ,  C09C1/3045 ,  C09C1/3072 ,  C09C1/309 ,  C01P2004/61 ,  C01P2004/62 ,  C01P2006/12 ,  C01P2006/14

Abstract: There is disclosed a method of producing etched non-porous particles. The method includes, in some examples, coating a non-porous particle with a hydrophilic polymer and treating the coated particle with acid or base. Also provided is etched non-porous particles capable of separating a variety of analytes, including biomolecules.

公开(公告)号：US20240102932A1

公开(公告)日：2024-03-28

申请号：US18261751

申请日：2021-12-30

Applicant: Agilent Technologies, Inc.

Inventor： Victor LIM ,  Adrienne MCCAMPBELL ,  Qingyu WANG

IPC: G01N21/64 ,  G01N1/06 ,  G06V10/25 ,  G06V10/774 ,  G06V10/82 ,  G06V20/69 ,  G16H30/40

CPC classification number: G01N21/6458 ,  G01N1/06 ,  G01N21/6486 ,  G06V10/25 ,  G06V10/774 ,  G06V10/82 ,  G06V20/698 ,  G16H30/40 ,  G01N2201/126

Abstract: The present disclosure is directed to an improved methods and systems using autofluorescence of naturally-occurring components in a sample embedded in an embedding medium. Methods and systems are provided for determining an amount of tissue or cell preparation exposed at a surface of an embedded sample, and for preparing a tissue specimen comprising a region of interest (ROI) from an embedded sample. Methods and systems are also provided for imaging a sample of a biological tissue, and for identifying different cell types in an embedded tissue sample.

公开(公告)号：US20240093353A1

公开(公告)日：2024-03-21

申请号：US18262680

申请日：2022-02-24

Applicant: AGILENT TECHNOLOGIES, INC.

Inventor： Jing TANG ,  Elizabeth CARR

IPC: C23C14/16 ,  C23C14/02 ,  C23C14/34

CPC classification number: C23C14/16 ,  C23C14/024 ,  C23C14/34

Abstract: A multilayer coating including an adhesion layer; and a protective coating is disclosed. The multilayer coating can be applied to a portion of at least one of a base and a tip of an interface cone. A method of making a coated interface cone is also disclosed.

公开(公告)号：US11926870B2

公开(公告)日：2024-03-12

申请号：US17172540

申请日：2021-02-10

Applicant: Agilent Technologies, Inc.

Inventor： Jurgen Del Favero

IPC: C12Q1/68 ,  C12Q1/6818 ,  C12Q1/6851 ,  C12Q1/6853 ,  C12Q1/686

CPC classification number: C12Q1/686 ,  C12Q1/6818 ,  C12Q1/6851 ,  C12Q1/6853 ,  C12Q2525/131 ,  C12Q2525/301 ,  C12Q2537/143 ,  C12Q2561/113 ,  C12Q2565/101

Abstract: The present invention relates to the technical field of nucleic acid amplification using a Polymerase Chain Reaction (PCR). Specifically, the present invention relates to Polymerase Chain Reaction (PCR) primers and Polymerase Chain Reaction (PCR) nucleic acid amplification mixture and the use thereof in (quantitative) Polymerase Chain Reactions (PCR). Specifically, the present invention relates to Polymerase Chain Reaction (PCR) primers suitable for use in Restriction Mediated quantitative PCR (RM-qPCR) nucleic acid amplification reactions comprising a 5′ Acceptor representing one member of a fluorescence resonance energy transfer (FRET) pair; A representing a nucleic acid sequence motif of 10 to 30 bp; 3-C representing a linker region comprised of at least three carbon atoms; B representing a double stranded restriction enzyme recognition site or a random nucleic acid sequence; A′ representing a nucleic acid sequence motif of 10 to 30 bp being complementary to the nucleic acid sequence motif of A; and R-prim representing a nucleic acid sequence complementary to a target sequence in a nucleic acid sequence to be amplified.