公开(公告)号：US20190197692A1

公开(公告)日：2019-06-27

申请号：US16329415

申请日：2017-09-04

Applicant: RaySearch Laboratories AB

Inventor： Ola WEISTRAND

IPC: G06T7/12 ,  G06T7/149

CPC classification number: G06T7/12 ,  G06T7/149 ,  G06T7/174 ,  G06T2207/10072 ,  G06T2207/20096 ,  G06T2207/30004

Abstract: An anatomic structure of interest is contoured in 3D source data by selecting a first subset of data in a first image slice at a first axial position (z1). A first set of instructions identifies a first edge (E1) of the anatomic structure of interest in the first image slice. Then, a second subset of data is selected in a second image slice at a second axial position (z2); and a second set of instructions identifies a second edge (E2) of the anatomic structure of interest in the second image slice. A three-dimensional shell (3DS) is calculated based on the first and second edges (E1; E2) and the source data (SD). The three-dimensional shell (3DS) represents an approximation of a delimiting surface that separates the anatomic structure of interest from adjoining tissues in the 3D source data.

公开(公告)号：US20180221685A1

公开(公告)日：2018-08-09

申请号：US15580765

申请日：2016-06-09

Applicant: RaySearch Laboratories AB

Inventor： Kjell ERIKSSON

IPC: A61N5/10 ,  G16H50/20

CPC classification number: A61N5/1036 ,  G06F19/3481 ,  G16H50/20

Abstract: An interpolation of deliverable radiotherapy treatment plans is facilitated by restricting the movement of the multi-leaf collimator leaves between optimization steps.

公开(公告)号：US20180182106A1

公开(公告)日：2018-06-28

申请号：US15738891

申请日：2016-06-23

Applicant: RaySearch Laboratories AB

Inventor： Ola WEISTRAND

IPC: G06T7/174 ,  G06T7/12 ,  G06T7/00 ,  G06T15/08 ,  G06T3/00

CPC classification number: G06T7/174 ,  G06T3/0081 ,  G06T7/0012 ,  G06T7/12 ,  G06T15/08 ,  G06T2200/04 ,  G06T2207/10072 ,  G06T2207/20041 ,  G06T2207/20096 ,  G06T2207/20104 ,  G06T2207/30056

Abstract: A data processing unit receives a reference image (IMG13D) of a deformable physical entity, a target image (IMG23D) of said physical entity, and a first region of interest (ROI13D) defining a first volume in the reference image (IMG13D) representing a reference image element. The reference image (IMG13D), the target image (IMG23D) and the first region of interest (ROI13D) all contain 3D datasets. In response to user commands (c1; c2), the data processing unit defines a first contour (C12D) in a first plane through the target image (IMG23D), which is presented to a user via a display unit together with graphic data reflecting the reference image (IMG13D), the target image (IMG23D) and the first region of interest (ROI13D). The first contour (C12D) is aligned with at least a portion of a first border (IEB1) of a target image element (IE3D) in the target image (IMG23D). The target image element (IE3D) corresponds to the reference image element in the reference image (IMG13D). Based on the first contour (C12D), the target image (IMG23D) and the first region of interest (ROI13D); the data processing unit determines a second region of interest (ROI23D) defining a second volume in the target image (IMG23D).

公开(公告)号：US20170333733A1

公开(公告)日：2017-11-23

申请号：US15533420

申请日：2016-06-23

Applicant: RaySearch Laboratories AB

Inventor： Lars GLIMELIUS ,  Tore ERSMARK ,  Martin JANSON

IPC: A61N5/10

CPC classification number: A61N5/1031 ,  A61N2005/1087 ,  A61N2005/1095 ,  A61N2005/1096

Abstract: An optimization method for ion based radiotherapy includes inverse planning based on optimization variables related to the particle energy, a range modulator or ridge filter, a block and/or a range compensator. This enables automatic optimization of complex cases.

公开(公告)号：US12285629B2

公开(公告)日：2025-04-29

申请号：US18005674

申请日：2021-06-14

Applicant: RaySearch Laboratories AB (Publ)

Inventor： Martin Janson ,  Agnes Angerud

IPC: A61N5/10 ,  G16H20/40

Abstract: In cases where material properties of a structure within or outside a patient receiving radiotherapy treatment, robust planning can be used, based on different scenarios with different material property values using a material override function present in the treatment planning system.
A computer-based method of generating a radiotherapy treatment plan for a patient, based on an image of the patient and a desired dose. In cases where material properties of a structure within or outside a patient receiving radiotherapy treatment, robust planning can be used, based on different scenarios with different material property values using a material override function present in the treatment planning system. Robust planning is performed based on the at least two scenarios to provide robust evaluation data for each of the at least two scenarios and/or a robust optimized treatment plan with respect to all values in the set of material override values.

公开(公告)号：US12179038B2

公开(公告)日：2024-12-31

申请号：US17415768

申请日：2019-12-12

Applicant: RaySearch Laboratories AB

Inventor： Albin Fredriksson ,  Rasmus Bokrantz ,  Erik Engwall ,  Kjell Eriksson ,  Lars Glimelius

IPC: A61N5/10

Abstract: A method of optimizing the use of resources in treatment planning involving more than one radiation set delivered to one or more patients, the radiation sets requiring different resources, respectively, wherein the optimization is performed using an optimization problem comprising an optimization function related to the first and second sets of resources. The method may be used for optimizing one plan for one patient, or a number of plans for different patients, in such a way that the available resources are used in the best possible way.

公开(公告)号：US12138480B2

公开(公告)日：2024-11-12

申请号：US17906201

申请日：2021-03-31

Applicant: RaySearch Laboratories AB (Publ)

Inventor： Tianfang Zhang

IPC: A61N5/10

Abstract: A method and apparatus for generating a radiation treatment plan for a volume comprising: receiving a first treatment plan upon which to base a second treatment plan, the first treatment plan indicative of a dose distribution; receiving at least one dose-distribution-derived function configured to provide a value based on at least part of the dose distribution; receiving a target for the respective value of each dose-distribution-derived function comprising receiving a probability distribution; determining an optimization problem, wherein the or each objective function is a function of the dose-distribution-derived function, the respective probability distribution and a respective loss function; performing the optimization process based on said optimization problem; and determining said second treatment plan.

公开(公告)号：US12090344B2

公开(公告)日：2024-09-17

申请号：US18262920

申请日：2022-02-03

Applicant: RaySearch Laboratories AB (Publ)

Inventor： Erik Traneus

IPC: A61N5/10

CPC classification number: A61N5/1081 ,  A61N5/1031 ,  A61N2005/1087 ,  A61N2005/1095

Abstract: A radiation delivery system includes a chair on which the patient may be seated during treatment and a modulating assembly (10) for use in radiotherapy comprises a modulator wheel (15), said modulator wheel being shaped as a rim defining the circumference of a circle or an elliptic shape, and having varying thickness around the circumference, said modulator wheel (15) being arranged in such a way that a beam traveling from a radiation source (13) to a patient will intersect the rim of the modulator wheel, said wheel being arranged to rotate in such a way that the beam will intersect the rim in varying positions around the circumference. The wheel will modulate the energy of the beams passing through material having varying thickness as the modulator wheel rotates.

公开(公告)号：US20240221899A1

公开(公告)日：2024-07-04

申请号：US18555004

申请日：2022-04-13

Applicant: RaySearch Laboratories AB (Publ)

Inventor： Erik TRANEUS ,  Albin FREDRIKSSON ,  Kjell ERIKSSON ,  Jakob ODÉN

IPC: G16H20/40 ,  A61N5/10

CPC classification number: G16H20/40 ,  A61N5/1038

Abstract: A combined set of treatment plans including radiation treatment and hyperthermia treatment may be optimized either by co-optimizing both plans together or by optimizing one of the plans and then optimizing the other taking into account the predicted effect of the first optimized plan.

公开(公告)号：US20240091558A1

公开(公告)日：2024-03-21

申请号：US18253931

申请日：2021-11-16

Applicant: RaySearch Laboratories AB

Inventor： Erik TRANEUS

IPC: A61N5/10 ,  G16H20/40

CPC classification number: A61N5/1031 ,  A61N5/1043 ,  G16H20/40 ,  A61N2005/1034

Abstract: A radiotherapy treatment planning method for achieving a FLASH radiotherapy treatment plan involves optimizing the plan using an optimization problem that has been designed to maximize the part of the irradiation that will be delivered under FLASH conditions, in particular to an organ at risk, to minimize the damage to the organ at risk.