公开(公告)号：US20230364602A1

公开(公告)日：2023-11-16

申请号：US18029996

申请日：2021-10-13

Applicant: DOTS Technology Corp.

Inventor： Adi Gilboa-Geffen ,  Brian Christopher Burke

IPC: B01L3/00 ,  G01N1/28 ,  G01N21/64

CPC classification number: B01L3/502 ,  G01N1/286 ,  G01N21/645 ,  B01L2200/10 ,  B01L2300/044 ,  B01L2300/0672 ,  B01L2300/0681 ,  B01L2300/087 ,  B01L2400/0644 ,  G01N2201/0221

Abstract: The present disclosure is drawn to devices and systems for target detection in samples (e.g., food samples and clinical samples). The allergen detection system includes a sampler, a disposable analytic cartridge and a detection device with an optimized optical system. The allergen detection utilizes nucleic acid molecules as detection agents and detection probes.

公开(公告)号：US11016094B2

公开(公告)日：2021-05-25

申请号：US16575440

申请日：2019-09-19

Applicant: DOTS Technology Corp.

Inventor： Adi Gilboa-Geffen

IPC: G01N33/58 ,  G01N33/542 ,  A61K38/00 ,  G01N33/53 ,  G01N33/68 ,  C12M1/34 ,  A61P37/00

Abstract: The present invention is drawn to nucleic acid aptamer based signaling polynucleotides (SPNs) for allergen detection in samples. Disclosed herein include compositions, compounds, assays and methods of using said SPNs to detect one or more allergens in a sample, particularly food allergens in a food product.

公开(公告)号：US20200071647A1

公开(公告)日：2020-03-05

申请号：US16487450

申请日：2018-02-21

Applicant: DOTS Technology Corp.

Inventor： Adi Gilboa-Geffen ,  Gregory J. Kintz ,  Adam J. Young ,  Patrick Murphy ,  Joshua Glenn Anthony ,  Paul Fleming ,  Brett Gorham ,  Ryan Griswold ,  Bruce Richardson

IPC: C12M3/06 ,  C12M1/32 ,  G01J3/42 ,  G01J3/44 ,  G01N21/51 ,  G01N21/64 ,  G01N21/53 ,  G01N33/02

Abstract: The present invention is drawn to devices and systems for allergen detection in a sample. The allergen detection system includes a sampler, a disposable analysis cartridge and a detection device with an optimized optical system. In some embodiments, the allergen detection utilizes aptamer nucleic acid molecules as detection agents. In some embodiments, the nucleic acids are conjugated to magnetic beads or solid surfaces such as glasses, microwells and microchips.

公开(公告)号：US20200024648A1

公开(公告)日：2020-01-23

申请号：US16419150

申请日：2019-05-22

Applicant: DOTS Technology Corp.

Inventor： Adi Gilboa-Geffen ,  Renuka Babu Brown

IPC: C12Q1/6818 ,  G01N33/02 ,  C12Q1/6811 ,  G01N33/53 ,  C12N15/10

Abstract: The present invention provides allergen detection molecules and devices useful in on-site and rapid detection of allergens, including food allergens.

公开(公告)号：US20200018764A1

公开(公告)日：2020-01-16

申请号：US16575440

申请日：2019-09-19

Applicant: DOTS Technology Corp.

Inventor： Adi Gilboa-Geffen

IPC: G01N33/58 ,  C12M1/34 ,  A61K38/00 ,  G01N33/68

Abstract: The present invention is drawn to nucleic acid aptamer based signaling polynucleotides (SPNs) for allergen detection in samples. Disclosed herein include compositions, compounds, assays and methods of using said SPNs to detect one or more allergens in a sample, particularly food allergens in a food product.