公开(公告)号：US3734601A

公开(公告)日：1973-05-22

申请号：US3734601D

申请日：1971-07-08

Applicant: BAXTER LABORATORIES INC

Inventor： HEISS L

IPC: G01N21/05 ,  G01N21/64 ,  G01N21/85 ,  G01N1/10 ,  G01N21/00

CPC classification number: G01N21/645 ,  G01N21/05 ,  G01N21/251 ,  G01N21/85 ,  G01N2021/054 ,  G01N2201/064

Abstract: A flow cell assembly for adapting an apparatus for both fluorometric and colorimetric studies. The assembly includes a holder having a folded optical path between an external light source and photosensitive response means. The light input to the optical path is at right angles to the light output therefrom so that the assembly may be employed in place of the sample cuvette of a conventional spectrofluorescence measuring instrument. The holder contains a flow tube having an offset sight passageway portion supported endwise in the optical path. The holder includes a light shield plate slotted to receive the legs of the offset portion and to substantially protect the offset sight passageway portion and the folded optical path from stray light. The flow tube may include an integral debubbler.

Abstract translation: 用于适应荧光和比色研究的装置的流动池组件。 组件包括在外部光源和光敏应答装置之间具有折叠光路的保持器。 输入到光路的光线与从其输出的光线成直角，因此可以使用该组件来代替传统的分光荧光测量仪器的样品杯。 保持器包括流管，其具有在光路中端向支撑的偏移视线通道部分。 保持器包括开槽的光屏蔽板，以接收偏移部分的腿部并且基本上保护偏移视线通道部分和折叠的光路免受杂散光线的影响。 流动管可以包括整体脱泡器。

公开(公告)号：US11703460B2

公开(公告)日：2023-07-18

申请号：US16913396

申请日：2020-06-26

Applicant: KLA Corporation

Inventor： Zhiwei Xu ,  Kurt Haller ,  J. K. Leong ,  Christian Wolters

IPC: G01N21/95 ,  G01N21/45

CPC classification number: G01N21/9505 ,  G01N21/45 ,  G01N2201/064 ,  G01N2201/06113

Abstract: Methods and systems for detecting and classifying defects based on the phase of dark field scattering from a sample are described herein. In some embodiments, throughput is increased by detecting and classifying defects with the same optical system. In one aspect, a defect is classified based on the measured relative phase of scattered light collected from at least two spatially distinct locations in the collection pupil. The phase difference, if any, between the light transmitted through any two spatially distinct locations at the pupil plane is determined from the positions of the interference fringes in the imaging plane. The measured phase difference is indicative of the material composition of the measured sample. In another aspect, an inspection system includes a programmable pupil aperture device configured to sample the pupil at different, programmable locations in the collection pupil.

公开(公告)号：US20180136133A1

公开(公告)日：2018-05-17

申请号：US15461613

申请日：2017-03-17

Applicant: BWT PROPERTY, INC.

Inventor： Jun Zhao ,  Xin Jack Zhou ,  Sean Xiaolu Wang

IPC: G01N21/65 ,  G01J3/02

CPC classification number: G01N21/65 ,  G01J3/0216 ,  G01J3/0218 ,  G01J3/4406 ,  G01N21/474 ,  G01N21/645 ,  G01N2201/064 ,  G01N2201/08

Abstract: This invention relates to a light delivery and collection device for performing spectroscopic analysis of a subject. The light delivery and collection device comprises a reflective cavity with two apertures. The first aperture is configured to receive excitation light which then diverges and projects onto the second aperture. The second aperture is configured to be applied close to the subject such that the reflective cavity substantially forms an enclosure covering a large area of the subject. The excitation light enters and interacts with the covered area of the subject to produce inelastic scattering and/or fluorescence emission from the subject. The reflective cavity has a specular reflective surface with high reflectivity to the excitation light as well as to the inelastic scattering and/or fluorescence emission from the subject. The reflective cavity reflects the excitation light that is reflected and/or back-scattered from the subject and redirects it towards the subject. This causes more excitation light to penetrate into a diffusely scattering subject to produce inelastic scattering and/or fluorescence emission from inside of the subject hence enabling sub-surface measurement. In addition, the reflective cavity reflects the inelastic scattering and/or fluorescence emission from the subject unless the inelastic scattering and/or fluorescence emission either emits from the first aperture of the reflective cavity to be measured with a spectrometer device, or re-enters the subject at the second aperture. This multi-reflection process improves the collection efficiency of the inelastic scattering or fluorescence emission from the subject.

公开(公告)号：US20180059031A1

公开(公告)日：2018-03-01

申请号：US15557904

申请日：2016-03-03

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： THOMAS J. BRACE ,  PHILLIP A. BOLEA ,  GIUSEPPE M. BOMMARITO ,  MICHELE A. WALDNER ,  STEPHEN R. ALEXANDER ,  FUSU THAO ,  KATLEEN M. STENERSEN

IPC: G01N21/94 ,  C12Q1/00 ,  C12Q1/66 ,  G01N21/76 ,  C12Q1/22

CPC classification number: G01N21/94 ,  C12Q1/008 ,  C12Q1/22 ,  C12Q1/66 ,  C12Q2304/60 ,  G01J1/0223 ,  G01J1/0233 ,  G01J1/0271 ,  G01J1/42 ,  G01N21/763 ,  G01N2201/021 ,  G01N2201/022 ,  G01N2201/0221 ,  G01N2201/064 ,  G01N2201/0646

Abstract: Various embodiments of a light detection device and a method of using the device are disclosed. In one or more embodiments, the light detection device can include a housing that extends along a housing axis between top and bottom surfaces. The device can also include a port that is adapted to receive a sample, and a door connected to the housing. The door can include an actuator portion adapted to selectively move the door between a closed position and an open position, and a cover portion connected to the actuator portion and adapted to close the port when the door is in the closed position and open the port when the door is in the open position to allow external access to the port.

公开(公告)号：US09897534B2

公开(公告)日：2018-02-20

申请号：US15292414

申请日：2016-10-13

Applicant: Nix Sensor Ltd.

Inventor： Matthew Sheridan

IPC: G01J3/46 ,  G01N21/25 ,  G01N21/01 ,  G01N33/08 ,  G01J3/50 ,  G01N21/03 ,  G01N21/47

CPC classification number: G01N21/251 ,  G01J3/50 ,  G01J3/501 ,  G01N21/01 ,  G01N21/03 ,  G01N21/255 ,  G01N33/08 ,  G01N2021/4757 ,  G01N2021/4769 ,  G01N2201/0221 ,  G01N2201/062 ,  G01N2201/064 ,  G01N2201/08

Abstract: The present concept is a method of preparing an egg to determine the color of the egg using an egg yolk cover. The egg yolk cover is dome-shaped with a base edge and inspection area. The egg yolk cover eliminates ambient light from impinging on the egg yolk and is used in combination with a light sensor to determine the color of egg yolks. The light sensor includes a single flat printed circuit board with a top and bottom side which includes at least one LED light and one color sensor, at least one light pipe receiving light from the LED and transmitting it onto a substrate at an angle theta and a tube frame including an optical tube for receiving light reflections from the substrate. The light pipes and the tube frame are compression fit between the printed circuit board and a lower housing. To determine the color of the egg yolk, the egg is first cracked onto a flat surface. The egg yolk cover is then placed over the egg yolk and the color sensor is placed onto the inspection area to measure the color.

公开(公告)号：US09804085B2

公开(公告)日：2017-10-31

申请号：US14670958

申请日：2015-03-27

Applicant: Fondarex S.A.

Inventor： Konrad Baumgartner ,  Yves Gerard Laurent Huguenin-Vuillemin

IPC: B22D2/00 ,  B22D17/14 ,  B22D17/20 ,  B22D17/32 ,  G01N21/3554 ,  G01N21/3504 ,  G01N21/85 ,  B22C9/06 ,  G01N21/15 ,  B29C45/34 ,  G01N21/359 ,  B29C45/76 ,  G01N21/84

CPC classification number: G01N21/3554 ,  B22C9/067 ,  B22D17/145 ,  B22D17/2007 ,  B22D17/32 ,  B29C45/34 ,  B29C45/76 ,  B29C2945/7614 ,  B29C2945/76254 ,  G01N21/15 ,  G01N21/3504 ,  G01N21/359 ,  G01N21/85 ,  G01N2021/151 ,  G01N2021/354 ,  G01N2021/8416 ,  G01N2021/8578 ,  G01N2201/024 ,  G01N2201/062 ,  G01N2201/0622 ,  G01N2201/0626 ,  G01N2201/064

Abstract: A device and a method are provided for measuring the moisture in die cast molds, the cavity of which is connected via an evacuation conduit to an evacuation device. The modular assembly of the device is connectable to the evacuation conduit and includes a sensor assembly to measure the moisture of gases evacuated from the mold cavity. The sensor assembly includes an emitter emitting electromagnetic radiation and a detector detecting electromagnetic radiation. On the basis of the measured values obtained during the evacuation action it can be determined whether the amount of a water/release agent mixture jetted into the mold cavity needs to be altered before the actual casting action.

公开(公告)号：US20170284989A1

公开(公告)日：2017-10-05

申请号：US15471016

申请日：2017-03-28

Applicant: Zoetis Services LLC

Inventor： John Hilbert Hebrank

IPC: G01N33/08 ,  G01N21/59

CPC classification number: G01N33/085 ,  G01N21/31 ,  G01N21/59 ,  G01N2201/064 ,  G01N2201/068

Abstract: An egg identification system for determining egg viability is provided. Such a system includes an emitter assembly for emitting electromagnetic radiation toward a plurality of eggs positioned proximate thereto. A detector assembly is positioned proximate to the emitter assembly. The detector assembly has a plurality of detectors fixedly positioned with respect to the emitter assembly and configured to detect electromagnetic radiation transmitted through the eggs. An optical shielding assembly is configured to move with respect to the detectors. A processor is in communication with detector assembly and is configured to determine viability of the eggs using the detected electromagnetic radiation. An associated method is also provided.

公开(公告)号：US09568417B2

公开(公告)日：2017-02-14

申请号：US14411373

申请日：2012-10-22

Applicant: ZHEJIANG UNIVERSITY

Inventor： Cuifang Kuang ,  Shuai Li ,  Xiang Hao ,  Zhaotai Gu ,  Xu Liu

IPC: G01J4/00 ,  G01N21/27 ,  G02B21/00 ,  G01N21/64 ,  G01N21/25 ,  G02B27/58

CPC classification number: G01N21/27 ,  G01N21/255 ,  G01N21/6458 ,  G01N2201/06113 ,  G01N2201/064 ,  G02B21/002 ,  G02B21/0032 ,  G02B21/0068 ,  G02B27/58

Abstract: This invention discloses a super-resolution microscopy method and device, of which the method comprises the following steps: converting laser beam into linearly polarized light after collimation; linearly polarized light is deflected and phase modulated by a spatial light modulator; the deflected beam is focused, collimated and then converted into circularly polarized light for projection on the sample to collect signal light from various scanning points on the sample, and obtaining the first signal light intensity; switching over modulation function to project linearly polarized light modulated by the second phase modulation on the sample to collect signal light from various scanning points on the sample, and obtaining the second signal light intensity; calculating valid signal light intensity to obtain the super-resolution image. This device features in a simple structure and easy operation, which can obtain a super-resolution beyond diffraction limit at a lower luminous power; it is quick in image formation with the frame frequency over 15 frames when the number of scanning points in each image is 512×512.

Abstract translation: 本发明公开了一种超分辨率显微镜方法和装置，其方法包括以下步骤：准直后将激光束转换成线偏振光; 线性偏振光被空间光调制器偏转和相位调制; 偏转光束被聚焦，准直，然后转换成圆偏振光，用于投射在样品上，以从样品上的各个扫描点收集信号光，并获得第一信号光强度; 切换调制功能，将样品上的第二相位调制调制的线偏振光投射到样品上的各个扫描点的信号光，并获得第二信号光强度; 计算有效信号光强度以获得超分辨率图像。 该器件结构简单，操作方便，可以在较低的发光功率下获得超过衍射极限的超分辨率; 当每个图像中的扫描点数量为512×512时，帧频超过15帧的图像形成速度很快。

公开(公告)号：US20160095519A1

公开(公告)日：2016-04-07

申请号：US14966824

申请日：2015-12-11

Applicant: SEIKO EPSON CORPORATION

Inventor： Hideto YAMASHITA ,  Yoshitaka IIJIMA

IPC: A61B5/00 ,  A61B5/0205

CPC classification number: A61B5/0059 ,  A61B5/02055 ,  A61B5/02427 ,  A61B5/02438 ,  A61B5/02444 ,  A61B5/14552 ,  A61B5/681 ,  A61B5/7278 ,  A61B2562/0219 ,  A61B2562/0238 ,  G01N21/474 ,  G01N21/49 ,  G01N2201/064

Abstract: A biological information detector includes a wristband, a housing, an opening, a light-emitting part, a reflecting part, a light-receiving part, and a protecting part. The opening is defined in a surface of the housing adapted to face a surface of the wrist of the user. The light-emitting part is disposed inside the housing and configured to emit green light. The reflecting part is disposed in periphery of the light emitting part, and configured to reflect the light emitted by the light-emitting part, wherein the reflecting part is disposed inside the housing. The light-receiving part is disposed inside the housing, and configured to receive reflected light reflected at a detection site of the wrist of the user. The protecting part is configured to protect the light-emitting part and the reflecting part, and is disposed at the opening of the housing to contact with the detection site.

Abstract translation: 生物信息检测器包括腕带，壳体，开口，发光部，反射部，受光部以及保护部。 开口限定在壳体的适于面向使用者手腕表面的表面中。 发光部配置在壳体的内部并配置为发出绿光。 反射部分设置在发光部分的周围，并且被配置为反射由发光部分发射的光，其中反射部分设置在壳体内。 光接收部设置在壳体内部，并且被配置为接收在用户的手腕的检测部位处反射的反射光。 保护部被配置为保护发光部和反射部，并且设置在壳体的开口处以与检测部位接触。

公开(公告)号：US20150300942A1

公开(公告)日：2015-10-22

申请号：US14434171

申请日：2013-10-07

Applicant: EMPA EIDGENÖSSISCHE MATERIAL-PRÜFUNGS- UND FORSCHUNGSANSTALT

Inventor： Markus Mangold ,  Bela Tuzson ,  Lukas Emmenegger

IPC: G01N21/03 ,  G01N21/3504

CPC classification number: G01N21/031 ,  G01N21/3504 ,  G01N2201/064

Abstract: A Multi-pass optical cell (1) with an internal space (11) for laser spectroscopy is described, which is able to reduce or eliminate interference fringes appearing by performing laser absorption spectroscopy in the multi-pass optical cells (1) leading to improved absorption spectra. This is achieved by using a multi-pass optical cell (1) comprising an absorption mask (3) which is permanently or removable mountable in the internal space (11) in a rotatably fixed manner, where in a mask wall (30) a plurality of m apertures (300) is formed, in which the position of each aperture (300) is adapted to a predefinable propagation path of a main optical beam and/or the resulting reflection spot pattern (211) defined by the geometry of the multi-pass optical cell (1) and the used angle of incidence of an initial beam (20), so that each aperture (300) is traversable by the main optical beam from a first side (301) to a second side (302).

Abstract translation: 描述了具有用于激光光谱的内部空间（11）的多通光学单元（1），其能够通过在多通道光学单元（1）中执行激光吸收光谱来减少或消除出现的干涉条纹，从而改善 吸收光谱。 这通过使用包括吸收掩模（3）的多通道光学单元（1）来实现，该吸收掩模永久地或可移除地以可旋转地固定的方式安装在内部空间（11）中，其中在掩模壁（30）中具有多个 形成m个孔（300），其中每个孔（300）的位置适合于主光束的预定义传播路径和/或由多光束的几何形状限定的所得到的反射光斑图案（211） 通过光学单元（1）和初始光束（20）的使用入射角，使得每个孔径（300）能够通过主光束从第一侧（301）到第二侧（302）穿过。