公开(公告)号：US20110068279A1

公开(公告)日：2011-03-24

申请号：US12853651

申请日：2010-08-10

Applicant: THEODORE DENIS FAY, JR.

Inventor： THEODORE DENIS FAY, JR.

IPC: G01J1/58 ,  G02B21/10

CPC classification number: G01N21/6458 ,  G01J3/14 ,  G01J2003/2826 ,  G01N21/64 ,  G01N21/6486 ,  G01N21/65 ,  G01N2021/6463 ,  G01N2201/061 ,  G01N2201/0683 ,  G02B21/10 ,  G02B21/16

Abstract: A fluorescence microscope includes a nearly monochromatic light source, a Brewster angle wedge, and an optical system for irradiating a sample with a light beam from the light source and directing fluorescence light from said sample onto the Brewster angle wedge. Collection optics are provided for focusing a hyper-spectral, wide angle and dark field image of the sample from the Brewster angle wedge onto recording optics.

Abstract translation: 荧光显微镜包括近似单色的光源，布鲁斯特角楔和用于从光源照射样品的光束并将来自所述样品的荧光引导到布鲁斯特角楔上的光学系统。 提供收集光学器件用于将来自布鲁斯特角楔的样品的超光谱，广角和暗场图像聚焦到记录光学器件上。

公开(公告)号：US20110058166A1

公开(公告)日：2011-03-10

申请号：US12667753

申请日：2008-07-30

Applicant: Koichiro Nakamura ,  Yuzo Sasaki ,  Kazuo Fujiura ,  Shogo Yagi

Inventor： Koichiro Nakamura ,  Yuzo Sasaki ,  Kazuo Fujiura ,  Shogo Yagi

IPC: G01J3/447 ,  G01J3/28

CPC classification number: G01J3/14 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0237 ,  G01J3/06 ,  G01J3/18 ,  G01J3/36 ,  G01J2003/064

Abstract: The present invention provides a small spectroscope that has a short response time. A spectroscope according to one embodiment of the present invention includes: a beam deflector that includes an electro-optic crystal, having an electro-optic effect, and paired electrodes used to apply an electric field inside the electro-optic crystal; spectroscopic means for dispersing light output by the beam deflector; and wavelength selection means for selecting light having an arbitrary wavelength from the light dispersed and output by the spectroscopic means.

Abstract translation: 本发明提供一种响应时间短的小型分光镜。 根据本发明的一个实施例的分光镜包括：光束偏转器，其包括具有电光效应的电光晶体，以及用于在电光晶体内施加电场的成对电极; 分光装置，用于分散由光束偏转器输出的光; 以及波长选择装置，用于从由分光装置分散和输出的光中选择具有任意波长的光。

公开(公告)号：US20100314554A1

公开(公告)日：2010-12-16

申请号：US12744125

申请日：2008-11-21

Applicant: Massimo Galimberti ,  Francesco Saverio Pavone

Inventor： Massimo Galimberti ,  Francesco Saverio Pavone

IPC: G01N21/64 ,  G02B5/18

CPC classification number: G01N21/6458 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0229 ,  G01J3/14 ,  G01J3/4406 ,  G01J2003/1286 ,  G01N21/645 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2201/0675

Abstract: A device to illuminate a object, to excite its fluorescence light emission, and detect the emitted fluorescence spectrum, comprising: at least one illumination system (13), adapted to receive light from a light source (11), to select at least one wavelength bands of light spectrum of the source (11), to illuminate a object (15) with light filtered in that way (14); and a detection system (17), adapted to detect fluorescence light (16) emitted by the object (15), to select at least one wavelength bands of fluorescence, light spectrum (16), to record the spectrum of the filtered light; characterized in that said illumination system (13) comprises: at least one first dispersive element (41), at least one focusing optics (43), at least one spatial fitter of excitation (44), at least one collimating optics (45) and at least one second dispersive element (47), wherein said detection system (17) comprises: at least one dispersive element (81), at least one focusing optics (83), at least one spatial filter of detection (84), at least one imaging optics (85) and at least one light detector (87).

Abstract translation: 用于照亮物体以激发其荧光发射并检测发射的荧光光谱的装置，包括：适于接收来自光源（11）的光的至少一个照明系统（13），以选择至少一个波长 源（11）的光谱带，用以这种方式过滤的光照射物体（15）（14）; 以及检测系统（17），其适于检测由所述物体（15）发射的荧光（16），以选择荧光的至少一个波长带（光谱），以记录所述滤光的光谱; 其特征在于，所述照明系统（13）包括：至少一个第一分散元件（41），至少一个聚焦光学器件（43），至少一个激发器空间拟合器（44），至少一个准直光学器件（45）和 至少一个第二分散元件（47），其中所述检测系统（17）包括：至少一个分散元件（81），至少一个聚焦光学元件（83），至少一个检测空间滤波器（84） 一个成像光学器件（85）和至少一个光检测器（87）。

公开(公告)号：US07839091B2

公开(公告)日：2010-11-23

申请号：US12063575

申请日：2006-02-03

Applicant: Seiji Kohashikawa ,  Toshiyuki Fujine

Inventor： Seiji Kohashikawa ,  Toshiyuki Fujine

IPC: H05B37/05

CPC classification number: H05B33/0869 ,  G01J1/0271 ,  G01J1/04 ,  G01J1/0407 ,  G01J1/0422 ,  G01J1/32 ,  G01J1/4228 ,  G01J3/14 ,  G01J2003/1213 ,  G02B6/0063 ,  G02B6/0068 ,  G02F1/13318 ,  G02F1/133603 ,  G02F1/133609 ,  H05B33/0821 ,  H05B33/0863 ,  H05B35/00 ,  H05B37/0272

Abstract: A light emission device capable of holding a uniform color in various environments is provided. A light source control device has a light detection device for detecting emission brightness of light sources that emit different colors and controlling emission brightness of at least one light source of the light sources based on the detection result of the light detection device. A through-hole is formed in a reflection member for reflecting light emitted from the light source, and the reflection is in a predetermined direction. The light detection device is provided across the reflection member from the light source, and the light propagation member is provided at the through-hole.

Abstract translation: 提供能够在各种环境中保持均匀颜色的发光装置。 光源控制装置具有光检测装置，用于根据光检测装置的检测结果，检测发出不同颜色的光源的发光亮度，并控制光源的至少一个光源的发光亮度。 在用于反射从光源发射的光的反射构件中形成通孔，并且反射处于预定方向。 光检测装置从光源穿过反射构件设置，光传播构件设置在通孔处。

公开(公告)号：US07724363B2

公开(公告)日：2010-05-25

申请号：US11324892

申请日：2006-01-04

Applicant: Malte Wachsmuth ,  Karsten Rippe ,  Gerrit Heuvelman

Inventor： Malte Wachsmuth ,  Karsten Rippe ,  Gerrit Heuvelman

IPC: G01N21/64

CPC classification number: G01N21/6458 ,  G01J3/14 ,  G01J3/36 ,  G02B21/0064 ,  G02B21/0072

Abstract: Many points on a sample are tested simultaneously in parallel in an FCS method with multifocal illumination and/or detection.

Abstract translation: 在具有多焦点照明和/或检测的FCS方法中，样本上的许多点被并行测试。

公开(公告)号：US20100004887A1

公开(公告)日：2010-01-07

申请号：US12380674

申请日：2009-03-02

Applicant: Johnathan Martin Mooney

Inventor： Johnathan Martin Mooney

IPC: G01J3/40 ,  G06F19/00

CPC classification number: G01J3/02 ,  G01J3/0237 ,  G01J3/0289 ,  G01J3/14 ,  G01J3/2803 ,  G01J3/2823 ,  G01J3/2889

Abstract: Apparatus for registering the spectral signature of a dynamic source event include an imaging-sensor array configured to register electromagnetic energy over a predetermined range of electromagnetic wavelengths and an optical system configured for imaging onto the imaging-sensor array a dispersion pattern of electromagnetic energy emitted from a source event external to the optical system. The optical system includes (i) a focusing element and (ii) a selected set of optical dispersion apparatus. Among the optical dispersion apparatus are at least a first optically dispersive element that disperses a first selected set of wavelengths within the sensitivity range of the imaging-sensor array and at least a second optically dispersive element that disperses a second selected set of wavelengths within the sensitivity range of the imaging-sensor array such that wavelengths emitted from a source event that are within the first and second selected sets of wavelengths impinge simultaneously upon the imaging-sensor array along, respectively, a first extrapolated axis and a second extrapolated axis that is non-parallel to the first extrapolated axis.

Abstract translation: 用于记录动态源事件的光谱特征的装置包括被配置为在电磁波长的预定范围内记录电磁能量的成像传感器阵列和被配置用于在成像传感器阵列上成像的电磁能量的散射图案 光学系统外部的源事件。 光学系统包括（i）聚​​焦元件和（ii）所选择的一组光学分散设备。 在光学分散装置中，至少是第一光学色散元件，其将成像传感器阵列的灵敏度范围内的第一选定组的波长分散，并且将至少第二光学色散元件分散在灵敏度范围内的第二选定组合 成像传感器阵列的范围使得从源事件发射的波长在第一和第二选定组合波长内同时在成像传感器阵列上分别沿着第一外插轴和第二外推轴非对称 平行于第一外推轴。

公开(公告)号：US20090303562A1

公开(公告)日：2009-12-10

申请号：US12135354

申请日：2008-06-09

Applicant: Christopher S. Koeppen ,  Steven E. Parks

Inventor： Christopher S. Koeppen ,  Steven E. Parks

IPC: G02B26/00

CPC classification number: G01J3/06 ,  G01J1/029 ,  G01J3/02 ,  G01J3/021 ,  G01J3/14 ,  G01J3/1804 ,  G01J2003/064 ,  G01J2003/1213 ,  G02B6/2931 ,  G02B6/29311 ,  G02B6/29313 ,  G02B6/29389 ,  G02B6/34

Abstract: For spectrally filtering at least one input beam, a first reflective element is configured to tilt to multiple tilt orientations that each corresponds to a different angle of propagation of at least one input beam. One or more optical elements are configured to change at least some of the relative angles of propagation of the input beam for different tilt orientations of the first reflective element. A spectrally dispersive element is configured to receive the input beam at a location at which the central ray of the input beam is incident at different points on the spectrally dispersive element for each of the tilt orientations, and configured to disperse spectral components of the input beam at different respective angles in a spectral plane. The first reflective element is configured to tilt to select at least one and fewer than all of the dispersed spectral components to be directed to a selected output path.

Abstract translation: 为了对至少一个输入光束进行光谱滤波，第一反射元件被配置为倾斜到多个倾斜取向，其各自对应于至少一个输入光束的不同传播角度。 一个或多个光学元件被配置为改变用于第一反射元件的不同倾斜取向的输入光束的相对传播角度的至少一些。 光谱分散元件被配置为在输入光束的中心射线入射到用于每个倾斜取向的光谱色散元件上的不同点的位置处接收输入光束，并且被配置为分散输入光束的光谱分量 在光谱平面中以不同的相应角度。 第一反射元件被配置为倾斜以选择要被引导到所选择的输出路径的至少一个且少于所有分散的光谱分量。

公开(公告)号：US20090273777A1

公开(公告)日：2009-11-05

申请号：US12112205

申请日：2008-04-30

Applicant: Seok-Hyun Yun ,  Giuliano Scarcelli

Inventor： Seok-Hyun Yun ,  Giuliano Scarcelli

IPC: G01J3/00

CPC classification number: G01J3/26 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0229 ,  G01J3/14 ,  G01J3/18

Abstract: An exemplary embodiment of apparatus and method to measure and filter the spectrum of electro-magnetic radiation using multiple dispersive elements, such as diffraction gratings or VIPA etalons, concatenated in a cross-axis orthogonal arrangement can be provided. For example, it is possible to receive at least one first electro-magnetic radiation and generate at least one second electro-magnetic radiation using at least one first spectral separating arrangement. A first spectrum of the second electro-magnetic radiation can be dispersed along at least one first dispersive axis with respect to a propagation direction of the second electro-magnetic radiation. In addition, it is possible to, using at least one second arrangement, receive the second electro-magnetic radiation and produce at least one third electromagnetic radiation having a second spectrum dispersed along at least one second dispersive axis with respect to a propagation direction of the third electromagnetic radiation. The orientations of the respective first and second dispersive axes can be different from one another. The first and/or second dispersive arrangements can be VIPA etalon arrangements.

Abstract translation: 可以提供使用以横轴正交布置连接的多个色散元件（例如衍射光栅或VIPA标准具）来测量和过滤电磁辐射光谱的装置和方法的示例性实施例。 例如，可以使用至少一个第一光谱分离装置接收至少一个第一电磁辐射并产生至少一个第二电磁辐射。 第二电磁辐射的第一光谱可以相对于第二电磁辐射的传播方向沿着至少一个第一色散轴分散。 此外，可以使用至少一个第二布置来接收第二电磁辐射并且产生至少一个第三电磁辐射，该第三电磁辐射具有相对于第二电磁辐射的传播方向沿着至少一个第二色散轴分散的第二光谱 第三电磁辐射。 相应的第一和第二分散轴的取向可以彼此不同。 第一和/或第二分散装置可以是VIPA标准具配置。

公开(公告)号：US20090040521A1

公开(公告)日：2009-02-12

申请号：US12154859

申请日：2008-05-27

Applicant: Zhilin Hu ,  Andrew M. Rollins

Inventor： Zhilin Hu ,  Andrew M. Rollins

IPC: G01J3/45

CPC classification number: G01J3/14 ,  G01B9/02044 ,  G01B9/02091 ,  G01B2290/20 ,  G01J3/02 ,  G01J3/0208

Abstract: This application describes a spectrometer that includes a set of collimating optics to collimate received EMR to produce a collimated EMR. The spectrometer also includes a first dispersive optical element for dispersing the collimated EMR and a second dispersive optical element spaced apart from the first dispersive optical element to produce further dispersed EMR. The first dispersive optical element and the second dispersive optical element cooperate to disperse received EMR into a plurality of even frequency spaced EMR spectra. The spectrometer also includes a detector positioned to receive the EMR after passing though an optical path that includes the set of collimating optics, the first dispersive optical element, the second dispersive optical element, and a set of focusing optics.

Abstract translation: 该应用描述了一种光谱仪，其包括一组准直光学器件以准直所接收的EMR以产生准直的EMR。 光谱仪还包括用于分散准直EMR的第一色散光学元件和与第一色散光学元件间隔开的第二色散光学元件以产生进一步分散的EMR。 第一色散光学元件和第二色散光学元件协作以将接收到的EMR分散到多个均匀间隔的EMR光谱中。 光谱仪还包括一个检测器，定位成在通过包括准直光学器件组，第一分散光学元件，第二分散光学元件和一组聚焦光学器件的光路之后接收EMR。

公开(公告)号：US07408641B1

公开(公告)日：2008-08-05

申请号：US11058153

申请日：2005-02-14

Applicant: Hidong Kwak ,  Shankar Krishnan ,  Shing Lee ,  Haixing Zou

Inventor： Hidong Kwak ,  Shankar Krishnan ,  Shing Lee ,  Haixing Zou

IPC: G01J4/00

CPC classification number: G01J3/10 ,  G01B11/0641 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0224 ,  G01J3/0237 ,  G01J3/14 ,  G01J3/1809 ,  G01N21/211 ,  G01N21/9501 ,  G01N21/956 ,  G01N2021/212 ,  G01N2021/213 ,  G01N2021/95676

Abstract: An illumination subsystem configured to provide illumination for a measurement system includes first and second light sources configured to generate light for measurements in different wavelength regimes. The illumination subsystem also includes a TIR prism configured to be moved into and out of an optical path from the first and second light sources to the measurement system. If the TIR prism is positioned out of the optical path, light from only the first light source is directed along the optical path. If the TIR prism is positioned in the optical path, light from only the second light source is directed along the optical path. Various measurement systems are also provided. One measurement system includes an optical subsystem configured to perform measurements of a specimen using light in different wavelength regimes directed along a common optical path. The different wavelength regimes include vacuum ultraviolet, ultraviolet, visible, and near infrared wavelength regimes.

Abstract translation: 被配置为为测量系统提供照明的照明子系统包括被配置为产生用于不同波长方案中的测量的光的第一和第二光源。 照明子系统还包括被配置为移入和移出从第一和第二光源到测量系统的光路的TIR棱镜。 如果TIR棱镜位于光路外，则仅沿着光路引导来自第一光源的光。 如果TIR棱镜位于光路中，则仅沿着光路引导来自第二光源的光。 还提供了各种测量系统。 一个测量系统包括光学子系统，该光学子系统被配置为使用沿着公共光路引导的不同波长方式的光来对样本进行测量。 不同的波长方案包括真空紫外线，紫外线，可见光和近红外波长方案。