KINEMATICS PATH METHOD FOR LASER-INDUCED BREAKDOWN SPECTROSCOPY

    公开(公告)号:US20230358684A1

    公开(公告)日:2023-11-09

    申请号:US18026181

    申请日:2021-08-03

    Inventor: Fabio Demarco

    CPC classification number: G01N21/718 G01J3/443 G01N2201/06113

    Abstract: A method for compositional analysis includes providing a sample having a surface and determining with a controller a plurality of equidistant positions along an oscillatory path along the surface. The oscillatory path is sinusoid in at least one orthogonal dimension within a plane approximately parallel to the surface. The method further includes, for each equidistant position of the plurality of equidistant position, moving an ablation point along the oscillatory path to the each equidistant position, pulsing an energy source to provide an electromagnetic energy beam to ablate material at the ablation point, and collecting an emission spectrum with a spectrographic instrument in response to pulsing the energy source. The method also includes analyzing the emission spectrum to determine a composition at the surface.

    PORTABLE BIOSENSOR FOR AIR SAMPLE
    47.
    发明公开

    公开(公告)号:US20230296526A1

    公开(公告)日:2023-09-21

    申请号:US18123679

    申请日:2023-03-20

    Abstract: Provided is a portable biosensor that includes a sample filter cartridge, a filter collector, an optical sphere, an electromagnetic radiation emitter, a photo-detector, a processor, a signal display, a vacuum pump, and a power supply. The sample filter cartridge selectively removes small molecules to minimize spectral interference in the detection signal. The sample is concentrated onto the filter collector and subjected to illumination by the electromagnetic radiation emitter, producing Raman-scattering. The optical sphere collects and distributes the Raman-scattering shifts, which then pass through a spectral filter to produce spectral filtered scattering, which is then reflected by the concave holographic flat-field grating onto the photo-detector. The data is displayed graphically to provide the Raman-scattering shift data. The data is compared with a database for sample identification. The device is contained within a housing that is small enough to be easily transported for field use.

    Three-photon light sheet imaging
    50.
    发明授权

    公开(公告)号:US11762180B2

    公开(公告)日:2023-09-19

    申请号:US16622542

    申请日:2018-06-15

    Inventor: Kishan Dholakia

    Abstract: A light sheet imaging system, such as a light sheet microscope, comprises an illumination arrangement for generating a light sheet for three-photon excitation of a fluorescent sample, and a fluorescence collection arrangement for collecting fluorescence generated in the sample as a result of three-photon excitation by the light sheet. The light sheet may be a non-diffractive, propagation-invariant light sheet. The light sheet may be formed from and/or comprise a Bessel beam. A method of light sheet imaging comprises using a light sheet for three-photon excitation of a fluorescent sample, and collecting fluorescence generated in the sample as a result of three-photon excitation of the sample by the light sheet. Such a method may be used for light sheet microscopy.

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