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    ENHANCED SURFACE PLASMON RESONANCE METHOD
    41.
    发明申请
    ENHANCED SURFACE PLASMON RESONANCE METHOD 审中-公开

    公开(公告)号：US20170219571A1

    公开(公告)日：2017-08-03

    申请号：US15486039

    申请日：2017-04-12

    Applicant: Biosurfit S.A.

    Inventor： João Manuel Oliveira Garcia Da Fonseca

    IPC: G01N33/543 ,  G01N21/552 ,  G01N33/553 ,  G01N21/41

    CPC classification number: G01N33/54373 ,  G01N21/41 ,  G01N21/553 ,  G01N33/54346 ,  G01N33/553 ,  G01N2201/0612 ,  G01N2201/06146 ,  G01N2201/0621 ,  G01N2201/0635 ,  G01N2201/12723

    Abstract: The disclosure relates to processing SPR signals, in particular signals obtained by illuminating a conductive surface with light at two wavelengths. Embodiments—involve processing a first and second signal indicative of an intensity of light, received from a conductive layer at which SPR has occurred, as a function of angle of incidence, reflection or diffraction at the layer (depending on whether the incident light beam is received by a detector recording it in reflection or transmission from the conductive layer). The first and second signals each have two dips corresponding to a respective wavelength of the light at a respective angle at which surface plasmon resonance occurs for the respective wavelength and a peak between the two dips. The processing includes deriving a first and second value of a quantity indicative of signal magnitudes in the region of the peak. The method then provides for comparing the first and second values to detect a change in refractive index at the layer after the first signal and before the second signal was captured.

    METHOD AND APPARATUS FOR INSPECTING LAMINATED IRON CORE
    43.
    发明申请
    METHOD AND APPARATUS FOR INSPECTING LAMINATED IRON CORE 有权
    检查层压铁芯的方法和装置

    公开(公告)号：US20160299087A1

    公开(公告)日：2016-10-13

    申请号：US15088620

    申请日：2016-04-01

    Applicant: MITSUI HIGH-TEC, INC. ,  TOYOTA JIDOSHA KABUSHIKI KAISHA

    Inventor： Tadashi SHIBUTA ,  Masashi MATSUMOTO ,  Tatsuhiko MIZUTANI ,  Yoshitada YAMAGISHI

    IPC: G01N21/94 ,  G01N21/88

    CPC classification number: G01N21/94 ,  G01N21/8851 ,  G01N21/954 ,  G01N2201/06146 ,  G01N2201/105

    Abstract: There is provided a method for inspecting a laminated iron core structured by laminating a plurality of iron core pieces-having a predetermined shape and including therein a cooling flow path allowing refrigerant to flow therethrough, the refrigerant being supplied and discharged through openings formed at different positions. The method includes arranging a light projecting part and a light receiving part of a photosensor in the openings of the cooling flow path, respectively, and detecting light from the light projecting part by the light receiving part to thereby inspect a penetrating state of the cooling flow path.

    Abstract translation: 提供了一种检查层叠铁芯的方法，该层叠铁芯通过层叠多个具有预定形状的铁芯片而形成，其中包括允许制冷剂流过的冷却流路，制冷剂通过形成在不同位置的开口供给和排出 。 该方法包括分别在冷却流路的开口中布置光传感器的光投射部分和光接收部分，并且通过光接收部分检测来自光投射部分的光，从而检查冷却流的穿透状态 路径。

    Gemstone sparkle analysis
    46.
    发明授权
    Gemstone sparkle analysis 有权
    宝石闪耀分析

    公开(公告)号：US09250193B2

    公开(公告)日：2016-02-02

    申请号：US13575067

    申请日：2011-01-26

    Applicant: James Gordon Charters Smith

    Inventor： James Gordon Charters Smith

    IPC: G01N21/87 ,  G01N33/38 ,  G01N21/55

    CPC classification number: G01N21/87 ,  G01N21/55 ,  G01N33/381 ,  G01N2201/06146 ,  G01N2201/0634

    Abstract: A system is described for obtaining images of a gemstone, and performing quantitative analysis on the images to obtain measures of properties of the gemstone. The system comprises a support structure for supporting the gemstone at an observation position. An illumination structure is arranged to illuminate the gemstone. The illumination structure comprises a plurality of radially dispersed directional light sources directed towards the observation position, the support structure and illumination system being rotatable relative to one another around a rotation axis so that the gemstone can be illuminated by one or more of the directional light sources at each of a plurality of rotational positions, the axis of rotation being normal to a selected facet of the gemstone. An imaging device is directed towards the gemstone for obtaining images of the gemstone at each of the rotational positions, the imaging device having an imaging axis parallel to or coincident with the axis of rotation. An image processor is provided for identifying sparkle regions in the images corresponding to reflections from individual light sources by individual facets and providing a quantitative measure of the gemstone on the basis of porperties of the sparkle regions.

    Abstract translation: 描述了一种用于获得宝石图像的系统，并对图像进行定量分析以获得宝石特性的度量。 该系统包括用于在观察位置支撑宝石的支撑结构。 布置照明结构来照亮宝石。 照明结构包括指向观察位置的多个径向分散的定向光源，支撑结构和照明系统可围绕旋转轴线相对于彼此旋转，使得宝石能够被一个或多个定向光源 在多个旋转位置中的每一个处，所述旋转轴线垂直于所述宝石的选定小面。 成像装置被引向宝石，以在每个旋转位置获得宝石的图像，成像装置具有与旋转轴线平行或重合的成像轴。 提供图像处理器用于识别对应于各个光源的各个光源的反射的图像中的闪耀区域，并且基于闪光区域的特征提供宝石的定量测量。

    PROCESSING APPARATUS AND PARTICLE SECURING METHOD
    47.
    发明申请
    PROCESSING APPARATUS AND PARTICLE SECURING METHOD 有权
    加工装置和颗粒保护方法

    公开(公告)号：US20150268165A1

    公开(公告)日：2015-09-24

    申请号：US14644717

    申请日：2015-03-11

    Applicant: KONICA MINOLTA, INC.

    Inventor： Keita SAITO ,  Midori SHIMOMURA ,  Dai SUWAMA ,  Sayaka MORITA

    IPC: G01N21/49 ,  G01N21/55

    CPC classification number: G01N21/49 ,  G01N21/55 ,  G01N2201/06146 ,  G01N2201/124

    Abstract: A processing apparatus includes: a light emission unit configured to emit light to a surface of a particle dispersed liquid applied to a base material, the particle dispersed liquid having particles dispersed in a solvent; a reflected light amount monitoring unit configured to detect an amount of the light reflected, and monitor a temporal variation of the detected value; and a condition adjustment unit configured to adjust a condition for a particle securing process, the particle securing process being performed to remove the solvent and secure the particles onto the base material, wherein, when the temporal variation falls within a predetermined range after the value has reached an extreme value, securing of the particles is determined to have been completed.

    Abstract translation: 一种处理装置包括：发光单元，被配置为向施加到基材的颗粒分散液体的表面发光，所述颗粒分散液体具有分散在溶剂中的颗粒; 反射光量监视单元，被配置为检测反射的光量，并监视检测值的时间变化; 以及条件调整单元，被配置为调整用于颗粒固定过程的条件，进行所述颗粒固定处理以除去溶剂并将颗粒固定在基材上，其中，当所述时间变化落在所述值具有 达到极限值，确定颗粒的确定已经完成。

    Method for detection of analyte in microarray of samples and apparatus for performing such method
    48.
    发明授权
    Method for detection of analyte in microarray of samples and apparatus for performing such method 有权
    用于检测样品的微阵列中的分析物的方法和用于进行这种方法的装置

    公开(公告)号：US08547552B2

    公开(公告)日：2013-10-01

    申请号：US13121712

    申请日：2009-10-09

    Applicant: Cheung Hoi Albert Yu ,  Lok Ting Lau

    Inventor： Cheung Hoi Albert Yu ,  Lok Ting Lau

    IPC: G01N21/00

    CPC classification number: G01N21/00 ,  G01N21/253 ,  G01N21/554 ,  G01N33/587 ,  G01N2021/258 ,  G01N2021/3185 ,  G01N2201/06146

    Abstract: A method for detecting a target analyte associated with nano-sized gold- and/or silver-containing detecting labels in a microarray of samples. The labels indicate presence or absence of a target analyte in a sample. The method includes sequentially illuminating at least two sample groups with at least two different monochromatic light beams. The sample groups include (a) a first sample group containing at least one sample potentially containing the target analyte, and (b) a second sample group serving as positive control or negative control. The method also includes (ii) detecting intensity of light reflected, absorbed, or emitted from each of the sample groups when illuminated with each of the monochromatic light beams. (iii) recording groups of values associated with the intensity reflected, absorbed, or emitted light. (iv) comparing the groups of values associated with the sample groups; and (v) determining the presence of the target analyte based on the comparison.

    Abstract translation: 一种用于检测与样品微阵列中的纳米尺寸的含金和/或含银检测标签物相关的目标分析物的方法。 标签表示样品中存在或不存在目标分析物。 该方法包括用至少两个不同的单色光束顺序地照射至少两个样本组。 样品组包括（a）含有至少一种可能含有目标分析物的样品的第一样品组，和（b）用作阳性对照或阴性对照的第二样品组。 该方法还包括（ii）当用每个单色光束照射时，检测从每个样本组反射，吸收或发射的光的强度。 （iii）记录与反射，吸收或发射的光强度相关联的值的组。 （iv）比较与样本组相关的值组; 和（v）基于比较确定目标分析物的存在。

    SYSTEMS AND METHODS FOR DIAGNOSIS OF EPITHELIAL LESIONS
    49.
    发明申请
    SYSTEMS AND METHODS FOR DIAGNOSIS OF EPITHELIAL LESIONS 审中-公开
    用于诊断上皮层的系统和方法

    公开(公告)号：US20120057145A1

    公开(公告)日：2012-03-08

    申请号：US13029992

    申请日：2011-02-17

    Applicant: James W. Tunnell ,  Brandon Nichols ,  Narasimhan Rajaram ,  Sheldon F. Bish ,  Liang Lim

    Inventor： James W. Tunnell ,  Brandon Nichols ,  Narasimhan Rajaram ,  Sheldon F. Bish ,  Liang Lim

    IPC: G01J3/42 ,  G01N21/00 ,  G01N21/55 ,  G01J3/44

    CPC classification number: G01N21/474 ,  A61B5/0075 ,  A61B5/444 ,  G01J3/42 ,  G01N21/31 ,  G01N21/6486 ,  G01N21/65 ,  G01N2021/1736 ,  G01N2021/174 ,  G01N2201/0221 ,  G01N2201/06113 ,  G01N2201/06146 ,  G01N2201/0833

    Abstract: Systems comprising an optical fiber switch connected to a light source and an optical fiber probe, the optical fiber probe comprising a first optical fiber connected to the optical fiber switch and a second optical fiber connected to a spectrophotometer. Methods for determining one or more tissue parameters comprising: emitting light from a first optical fiber into a tissue; collecting the light reemitted from the tissue with a second optical fiber; generating a spectra of the light reemitted from the tissue with a spectrophotometer; and utilizing a look-up table based algorithm to determine one or more tissue parameters, wherein the lookup-table based algorithm comprises the steps of: generating a look-up table by measuring the functional form of a reflectance measured by the spectrophotometer using one or more calibration standards with known optical properties; and implementing an iterative fitting routine based on the lookup-table.

    Abstract translation: 包括连接到光源的光纤开关和光纤探针的系统，所述光纤探针包括连接到光纤开关的第一光纤和连接到分光光度计的第二光纤。 用于确定一个或多个组织参数的方法，包括：将光从第一光纤发射到组织中; 用第二光纤收集从组织再发射的光; 用分光光度计产生从组织再发射的光的光谱; 以及利用基于查找表的算法来确定一个或多个组织参数，其中所述基于查找表的算法包括以下步骤：通过测量由所述分光光度计测量的反射率的函数形式来生成查找表，使用一个或多个 具有已知光学性能的更多校准标准; 并且基于查找表来实现迭代拟合例程。

    METHOD FOR DETECTION OF ANALYTE IN MICROARRAY OF SAMPLES AND APPARATUS FOR PERFORMING SUCH METHOD
    50.
    发明申请
    METHOD FOR DETECTION OF ANALYTE IN MICROARRAY OF SAMPLES AND APPARATUS FOR PERFORMING SUCH METHOD 有权
    用于检测样品微量分析仪的方法和用于实施这种方法的装置

    公开(公告)号：US20110176135A1

    公开(公告)日：2011-07-21

    申请号：US13121712

    申请日：2009-10-09

    Applicant: Cheung Hoi Albert Yu ,  Lok Ting Lau

    Inventor： Cheung Hoi Albert Yu ,  Lok Ting Lau

    IPC: G01N21/00 ,  G01N21/59 ,  B82Y15/00

    CPC classification number: G01N21/00 ,  G01N21/253 ,  G01N21/554 ,  G01N33/587 ,  G01N2021/258 ,  G01N2021/3185 ,  G01N2201/06146

    Abstract: A method for detecting a target analyte associated with nano-sized gold- and/or silver-containing detecting labels in a microarray of samples. The labels indicate presence or absence of a target analyte in a sample. The method includes sequentially illuminating at least two sample groups with at least two different monochromatic light beams. The sample groups include (a) a first sample group containing at least one sample potentially containing the target analyte, and (b) a second sample group serving as positive control or negative control. The method also includes (ii) detecting intensity of light reflected, absorbed, or emitted from each of the sample groups when illuminated with each of the monochromatic light beams. (iii) recording groups of values associated with the intensity reflected, absorbed, or emitted light. (iv) comparing the groups of values associated with the sample groups; and (v) determining the presence of the target analyte based on the comparison.

    Abstract translation: 一种用于检测与样品微阵列中的纳米尺寸的含金和/或含银检测标签物相关的目标分析物的方法。 标签表示样品中存在或不存在目标分析物。 该方法包括用至少两个不同的单色光束顺序地照射至少两个样本组。 样品组包括（a）含有至少一种可能含有目标分析物的样品的第一样品组，和（b）用作阳性对照或阴性对照的第二样品组。 该方法还包括（ii）当用每个单色光束照射时，检测从每个样本组反射，吸收或发射的光的强度。 （iii）记录与反射，吸收或发射的光强度相关联的值的组。 （iv）比较与样本组相关的值组; 和（v）基于比较确定目标分析物的存在。

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