Identification of analytes by an ion mobility spectrometer with formation of dimer analytes
    42.
    发明授权
    Identification of analytes by an ion mobility spectrometer with formation of dimer analytes 有权
    通过离子迁移谱仪识别分析物,形成二聚体分析物

    公开(公告)号:US08604422B2

    公开(公告)日:2013-12-10

    申请号:US13720259

    申请日:2012-12-19

    CPC classification number: H01J49/00 G01N27/622 H01J49/0031

    Abstract: The subject of the invention is a method for identification of analytes with an ion mobility spectrometer by performing a series of measurements while varying the residence time of the analytes in the reaction space and identifying of monomer and nascent dimer analytes in the spectra so obtained.

    Abstract translation: 本发明的主题是通过在改变分析物在反应空间中的停留时间并确定如此获得的光谱中的单体和新生二聚体分析物的同时进行一系列测量来用离子迁移谱仪鉴定分析物的方法。

    BIO-CHIP FOR SECONDARY ION MASS SPECTROSCOPY AND METHOD OF FABRICATING THE SAME
    43.
    发明申请
    BIO-CHIP FOR SECONDARY ION MASS SPECTROSCOPY AND METHOD OF FABRICATING THE SAME 有权
    用于二次离子质谱的生物芯片及其制造方法

    公开(公告)号:US20130292561A1

    公开(公告)日:2013-11-07

    申请号:US13727018

    申请日:2012-12-26

    Abstract: There are provided a bio-chip for secondary ion mass spectrometry and a method of fabricating the same, the bio-chip, which is a bio-chip for analyzing a biochemical material using the secondary ion mass spectrometry, including: a substrate; and core-shell particles positioned above substrate, wherein the core-shell particles each include a metal nanoparticle as a core and a metal shell surrounding the metal nanoparticle.

    Abstract translation: 提供了二次离子质谱法的生物芯片及其制造方法,该生物芯片是使用二次离子质谱法分析生化材料的生物芯片,其包括:底物; 以及位于基材上方的核 - 壳颗粒,其中核 - 壳颗粒各自包括作为芯的金属纳米颗粒和围绕金属纳米颗粒的金属壳。

    Portable analytical system for on-site analysis of fluids
    44.
    发明授权
    Portable analytical system for on-site analysis of fluids 有权
    用于流体现场分析的便携式分析系统

    公开(公告)号:US08569685B2

    公开(公告)日:2013-10-29

    申请号:US12902611

    申请日:2010-10-12

    Applicant: Alan Finlay

    Inventor: Alan Finlay

    CPC classification number: G01N33/2823 H01J49/00

    Abstract: A portable analytical system for the rapid on-site analysis of fluids, and a method for using this system at the well-site for the analysis of samples extracted from drilling fluids is described. The portable analytical solution may be deployed at the well-site and used to perform detailed real-time analysis of formation fluids and extracts of rock cuttings. The method described could be used during hydrocarbon exploration and production to determine whether the drill stem has passed through a hydrocarbon-bearing region, or rocks that are capable of functioning as an oil reservoir or that may have been a source rock, or that may have come into contact with oil, or that may contain oil at present.

    Abstract translation: 描述了用于流体快速现场分析的便携式分析系统,以及在井场使用该系统用于分析从钻井液中提取的样品的方法。 便携式分析解决方案可以部署在井场,用于对地层流体和岩屑提取物进行详细的实时分析。 所描述的方法可以在碳氢化合物勘探和生产过程中使用,以确定钻杆是否已经通过含烃区域,或者能够作为油藏或可能是源岩的岩石,或者可能具有 与油接触,或者目前可能含有油。

    BIOMARKERS FOR PSORIASIS
    45.
    发明申请
    BIOMARKERS FOR PSORIASIS 审中-公开
    PSORIASIS的生物标志

    公开(公告)号:US20130280820A1

    公开(公告)日:2013-10-24

    申请号:US11610939

    申请日:2006-12-14

    Inventor: MARIBEL BEAUMONT

    Abstract: A group of polypeptides that are modulated in a psoriatic sample as compared to a normal sample is provided. These polypeptides can be used as biomarkers for diagnosis and monitoring treatment of psoriasis.

    Abstract translation: 提供了与正常样品相比在银屑病样品中调节的一组多肽。 这些多肽可用作诊断和监测牛皮癣治疗的生物标志物。

    Multimode cells and methods of using them
    46.
    发明授权
    Multimode cells and methods of using them 有权
    多模单元和使用它们的方法

    公开(公告)号:US08426804B2

    公开(公告)日:2013-04-23

    申请号:US13277594

    申请日:2011-10-20

    Abstract: A mass spectrometer is provided that is configurable for operation in both a Kinetic Energy Discrimination (KED) mode and a dynamic reaction cell (DRC) mode. To operate in the KED mode, a collision cell can be filled with a quantity of the inert gas, and an energy barrier can be formed between the collision cell and a downstream mass analyzer. To operate instead in the DRC mode, the collision cell can be filled with a quantity of gas that is reactive with the interferer ions.

    Abstract translation: 提供了可配置为在动能分辨(KED)模式和动态反应池(DRC)模式下操作的质谱仪。 为了在KED模式下操作,可以将一定数量的惰性气体填充到碰撞池中,并且可以在碰撞池和下游质量分析器之间形成能量阻挡层。 为了在DRC模式下操作,碰撞单元可以填充一定量的与干扰源离子反应的气体。

    Ion detector for mass spectrometry, method for detecting ion, and method for manufacturing ion detector
    47.
    发明授权
    Ion detector for mass spectrometry, method for detecting ion, and method for manufacturing ion detector 有权
    用于质谱的离子检测器,用于检测离子的方法和用于制造离子检测器的方法

    公开(公告)号:US08410415B2

    公开(公告)日:2013-04-02

    申请号:US13279081

    申请日:2011-10-21

    CPC classification number: H01J43/10 H01J49/00

    Abstract: The present disclosure provides an ion detector for improving the effect of electric field for pulling in an ion to be detected to a first-stage electrode of a secondary electron multiplier (SEM), and improving the effect of a stray light reduction. In one example embodiment, an ion detector includes a SEM, and a lead-in electrode for pulling in an ion to a first-stage electrode side of the SEM. At least one of the area of the lead-in electrode and a potential difference between the lead-in electrode and neighboring electrodes of the lead-in electrode, the neighboring electrode being an electrode not of the SEM, is set so that the light amount of internal-stray light generated inside the detector entering the first-stage electrode is not more than that of external-stray light generated outside the detector entering the first-stage electrode, when an ion is introduced into the detector.

    Abstract translation: 本公开内容提供了一种离子检测器,用于改善用于将要检测的离子拉入二次电子倍增器(SEM)的第一级电极的电场效应,并提高杂散光减少的效果。 在一个示例性实施例中,离子检测器包括SEM和用于将离子拉入SEM的第一级电极侧的引入电极。 引入电极的区域中的至少一个和引入电极与引入电极的相邻电极之间的电位差设定为不是SEM的电极的相邻电极,使得光量 当离子被引入到检测器中时,进入第一级电极的检测器内部产生的内部杂散光不超过进入第一级电极的检测器外部产生的外部杂散光。

    ION DETECTOR FOR MASS SPECTROMETRY, METHOD FOR DETECTING ION, AND METHOD FOR MANUFACTURING ION DETECTOR
    49.
    发明申请
    ION DETECTOR FOR MASS SPECTROMETRY, METHOD FOR DETECTING ION, AND METHOD FOR MANUFACTURING ION DETECTOR 有权
    用于质谱分析的离子检测器,用于检测离子的方法和用于制造离子检测器的方法

    公开(公告)号:US20120097847A1

    公开(公告)日:2012-04-26

    申请号:US13279081

    申请日:2011-10-21

    CPC classification number: H01J43/10 H01J49/00

    Abstract: The present disclosure provides an ion detector for improving the effect of electric field for pulling in an ion to be detected to a first-stage electrode of a secondary electron multiplier (SEM), and improving the effect of a stray light reduction. In one example embodiment, an ion detector includes a SEM, and a lead-in electrode for pulling in an ion to a first-stage electrode side of the SEM. At least one of the area of the lead-in electrode and a potential difference between the lead-in electrode and neighboring electrodes of the lead-in electrode, the neighboring electrode being an electrode not of the SEM, is set so that the light amount of internal-stray light generated inside the detector entering the first-stage electrode is not more than that of external-stray light generated outside the detector entering the first-stage electrode, when an ion is introduced into the detector.

    Abstract translation: 本公开内容提供了一种离子检测器,用于改善用于将要检测的离子拉入二次电子倍增器(SEM)的第一级电极的电场效应,并提高杂散光减少的效果。 在一个示例性实施例中,离子检测器包括SEM和用于将离子拉入SEM的第一级电极侧的引入电极。 引入电极的区域中的至少一个和引入电极与引入电极的相邻电极之间的电位差设定为不是SEM的电极的相邻电极,使得光量 当离子被引入到检测器中时,进入第一级电极的检测器内部产生的内部杂散光不超过进入第一级电极的检测器外部产生的外部杂散光。

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