公开(公告)号：US11766030B2

公开(公告)日：2023-09-26

申请号：US16533578

申请日：2019-08-06

Applicant: Northeastern University

Inventor： Joseph Ayers ,  Mark Patterson ,  Jerome F. Hajjar ,  Milica Stojanovic ,  Amy Mueller ,  Marc Meyer ,  Scott Sagalow

IPC: A01K61/10 ,  A01K61/65 ,  A01K63/04 ,  F03B13/14 ,  A01K61/95 ,  A01K61/80

CPC classification number: A01K61/10 ,  A01K61/65 ,  A01K61/80 ,  A01K61/95 ,  A01K63/042 ,  F03B13/14

Abstract: Techniques and systems for robotic aquaculture are described. In one embodiment, for example, a mariculture system may include an aquatic animal containment system operative to hold a population of aquatic animals, the aquatic animal containment system comprising an enclosed hull having a receptacle configured to receive a mechanical core, the mechanical core configured to store at least one sub-system to implement at least one function of mariculture system, and a position management system operative to maintain the enclosed hull at a depth below a surface of a body of water. Other embodiments are described.

公开(公告)号：US20230295551A1

公开(公告)日：2023-09-21

申请号：US18021447

申请日：2021-08-17

Applicant: Northeastern University

Inventor： Linh TRUONG ,  David Medina CRUZ ,  Thomas WEBSTER

IPC: C12M1/00 ,  C12M1/12 ,  C12M1/04 ,  C12N1/20

CPC classification number: C12M29/10 ,  C12M23/04 ,  C12M23/34 ,  C12M25/02 ,  C12M23/24 ,  C12N1/20

Abstract: A continuous perfusion bioreactor for microbial synthesis of metallic nanoparticles provides synthesis of nanoparticles without washout of the microbial cells. The perfusion bioreactor includes an inlet fluidically coupled to a holding compartment with a first flow barrier, which disperses the medium into a reaction compartment suitable for culture of microbial cells which synthesize nanoparticles. A second flow barrier in the reaction compartment prevents washout of the microbial cells but enables collection of the nanoparticles suspended in depleted nutrient medium.

公开(公告)号：US20230287438A1

公开(公告)日：2023-09-14

申请号：US18026439

申请日：2021-09-15

Applicant: NORTHEASTERN UNIVERSITY ,  PRESIDENT AND FELLOWS OF HARVARD COLLEGE

Inventor： Neel S. Joshi ,  IIia Gelfat ,  Anton KAN

IPC: C12N15/70 ,  C12N15/62 ,  A61K9/00 ,  C12N1/20 ,  A61K35/74

CPC classification number: C12N15/70 ,  C12N15/62 ,  A61K9/0053 ,  C12N1/20 ,  A61K35/74

Abstract: Disclosed are methods for producing genetically modified bacteria, comprising introducing into said bacteria at least one engineered cryptic plasmid comprising a heterologous nucleic acid, wherein the heterologous nucleic acid comprises a nucleic acid sequence encoding a recombinant protein and a polypeptide secretion system for directing the recombinant protein to the outer membrane for secretion, wherein the bacteria do not comprise any native cryptic plasmids.

公开(公告)号：US11732582B2

公开(公告)日：2023-08-22

申请号：US17919439

申请日：2021-11-18

Applicant: Northeastern University

Inventor： Xiating Feng ,  Feng Lin ,  Chengxiang Yang ,  Jiuyu Zhang ,  Shiping Li ,  Tianyang Tong ,  Xiangxin Su

IPC: E21D9/10 ,  H05B6/80

CPC classification number: E21D9/1073 ,  H05B6/80 ,  H05B2206/044

Abstract: The invention provides a microwave plasma adaptive rock breaking device for microwave-insensitive rocks and a using method thereof, and relates to the technical field of rock breaking. The microwave plasma adaptive rock breaking device comprises a microwave system, a microwave plasma conversion system and a cutter head system. The microwave system and the microwave plasma conversion system are mounted in the cutter head system, and the microwave system is connected with the microwave plasma conversion system. Under the premise that only a microwave source is used to supply energy, the combined action of ordinary microwave irradiation and plasma irradiation in the form of high-temperature flame is realized, and a full-section hard rock tunnel boring machine is in cooperation for breaking rocks, so that the problem of microwave-induced cracks of the microwave-insensitive rocks is solved, and the application scope of a microwave rock breaking technology is enlarged.

公开(公告)号：US11703476B2

公开(公告)日：2023-07-18

申请号：US17083264

申请日：2020-10-28

Applicant: Northeastern University

Inventor： Meni Wanunu ,  Mohammadamin Alibakhshi ,  Xinqi Kang ,  Zhuoyu Zhang

IPC: G01N27/416 ,  B01L3/00 ,  G01N33/487

CPC classification number: G01N27/4166 ,  B01L3/50273 ,  B01L3/502707 ,  B01L3/502715 ,  G01N33/48721 ,  B01L2300/0645 ,  B01L2300/0832 ,  B01L2400/0406 ,  B01L2400/0415

Abstract: An apparatus is provided for sensing a molecule in a sample. The apparatus utilizes an electric field to draw molecules from a first chamber through an aperture, defined by a chemical layer, into a second chamber. The apparatus can detect a DNA molecule with, for example, 4, 5, or 6 unique base pairs. As molecules pass through the aperture, a sensor detects or measures a change in an electric parameter used to generate the electric field, thereafter translating the change in the electric parameter into information about the molecule. A divider element separates the first and second chambers and supports a chemical layer defining the aperture. The apparatus enables detection or measurement of molecules over prolonged time at a higher electric field strength than other nanopores, due to a combination of the shape of the divider, structural elements thereon, and thickness of the chemical layer at the aperture.

公开(公告)号：US11701046B2

公开(公告)日：2023-07-18

申请号：US16347049

申请日：2017-11-02

Applicant: Northeastern University

Inventor： Srinivas Sridhar ,  Craig Versek ,  Peter Bex

IPC: A61B5/291 ,  A61B5/378 ,  A61B3/10 ,  A61B5/00 ,  A61B5/16

CPC classification number: A61B5/291 ,  A61B5/378 ,  A61B5/4082 ,  A61B5/4088 ,  A61B5/6803 ,  A61B3/10 ,  A61B5/162 ,  A61B5/6831 ,  A61B5/7264 ,  A61B5/742 ,  A61B2562/0209 ,  A61B2562/14

Abstract: A portable wireless neuromonitoring device can be used to diagnose and/or treat conditions of the brain and vision system. The device includes a sensor unit mountable on the head of a human subject and capable of recording signals from the brain in EEG and/or EFEG (electric field encephalography) mode, and the device can be used for simultaneous stimulus display and recording with latency of less than 1 millisecond. The device also includes electrodes that allow rapid set-up and measurement with low impedance contact with the scalp. The device can also be used in conjunction with virtual reality or alternate reality environments.

公开(公告)号：US11679528B2

公开(公告)日：2023-06-20

申请号：US17574102

申请日：2022-01-12

Applicant: NORTHEASTERN UNIVERSITY ,  CHINA NORTHEAST ARCHITECTURAL DESIGN & RESEARCH INSTITUTE CO., LTD. ,  CHINA CONSTRUCTION TECHNOLOGY GROUP CO., LTD. ,  SHENYANG UNIVERSITY OF TECHNOLOGY ,  CHINA WEST CONSTRUCTION BUILDING MATERIALS SCIENCE RESEARCH INSTITUTE CO., LTD.

Inventor： Xiaowei Gu ,  Xinlong Zhang ,  Hao Wang ,  Yuxin Gao ,  Xiaohui Li ,  Weifeng Zhang ,  Zhangmiao Li ,  Jianping Liu ,  Qingdong Liu ,  Baokuan Ning ,  Peng Liu

IPC: B28B1/08 ,  B28B11/24 ,  B28B13/06 ,  C04B28/02 ,  B28B23/22

CPC classification number: B28B23/22 ,  B28B1/08 ,  B28B11/245 ,  B28B13/06 ,  C04B28/021

Abstract: The present disclosure relates to the technical field of solid waste recycling and fabricated buildings, and provides a solid waste large-mixing-amount concrete prefabricated laminated slab and a preparation method thereof. The solid waste large-mixing-amount concrete prefabricated laminated slab provided by the present disclosure comprises a prefabricated layer and a laminated layer. Transverse grooves and longitudinal grooves are formed in the surface of the prefabricated layer. During application, the grooves can be used for erecting pipelines, the contact area of the prefabricated layer and the laminated layer can also be increased, the combined effect of new concrete and old concrete is improved, the integrity of a floor slab is enhanced, and the effect of improving the overall stress capacity of the floor slab is achieved.

公开(公告)号：US20230163830A1

公开(公告)日：2023-05-25

申请号：US18093602

申请日：2023-01-05

Applicant: Northeastern University

Inventor： Michele POLESE ,  Francesco RESTUCCIA ,  Tommaso MELODIA

IPC: H04B7/08 ,  H04B7/06

CPC classification number: H04B7/086 ,  H04B7/088 ,  H04B7/0695

Abstract: A system and method for beam management in a wireless network are provided. A learning module having a trained classification module processes received I/Q input samples to determine transmitted beam information of incoming RF transmissions. The learning module includes a beam inference engine to determine waveforms waveform characteristics of incoming RF transmissions beams, and an angle of arrival engine operative to determine an angle of arrival of the incoming RF transmissions beams on an antenna array. An incoming RF transmission beam and angle of arrival are selected based on the determined waveforms for beam management operations.

公开(公告)号：US20230159659A1

公开(公告)日：2023-05-25

申请号：US17261245

申请日：2019-07-29

Applicant: Massachusetts Eye and Ear Infirmary ,  Northeastern University

Inventor： Benjamin S. Bleier ,  Angela Nocera ,  Mansoor Amiji

IPC: C07K16/38 ,  A61K45/06 ,  A61K9/00 ,  A61K31/573

CPC classification number: C07K16/38 ,  A61K45/06 ,  A61K9/0024 ,  A61K31/573

Abstract: Methods and compositions for the treatment of chronic rhinosinusitis in a subject, and more particularly to methods for treating chronic rhinosinusitis with nasal polyps in a subject with cystatin inhibitors.

公开(公告)号：US20230131958A1

公开(公告)日：2023-04-27

申请号：US17819981

申请日：2022-08-16

Applicant: Northeastern University

Inventor： Leila Deravi ,  Camille A. Martin ,  Amrita Kumar

IPC: A61K8/29 ,  A61Q17/04 ,  A61K8/81 ,  A61K8/25 ,  A61K8/73 ,  A61K8/02 ,  A61Q19/08 ,  A61K8/86 ,  A61K8/26 ,  A61K8/85 ,  C09B67/02 ,  A61K8/41 ,  A61K8/49 ,  C09B19/00 ,  C09B61/00

Abstract: Cosmetic and dermatological compositions, including color changing compositions, are provided which typically include a plurality of synthetic particles having a size in the micrometer or nanometer range. Each synthetic particle typically includes one or more aggregates of a pigment selected from phenoxazone, phenoxazine, and a derivate or precursor thereof, and a stabilizing material which has a refractive index larger than 1.45; the aggregates having a size larger than about 100 nm and the composition being biodegradable and biocompatible.