公开(公告)号：US11732245B2

公开(公告)日：2023-08-22

申请号：US17379359

申请日：2021-07-19

Applicant: The Trustees of the University of Pennsylvania

Inventor： Martin Lock ,  Mauricio Alvira

IPC: C12N7/02 ,  C12N15/86 ,  B01D15/38 ,  B01J20/281 ,  C12N15/864 ,  G01N21/33 ,  B01J41/05 ,  B01D15/16 ,  B01D15/36 ,  B01J41/20

CPC classification number: C12N7/02 ,  B01D15/3804 ,  B01J20/281 ,  C12N15/86 ,  C12N15/8645 ,  G01N21/33 ,  B01D15/166 ,  B01D15/363 ,  B01J41/05 ,  B01J41/20 ,  C12N2750/14143 ,  C12N2750/14151

Abstract: A two-step chromatography purification scheme is described which selectively captures and isolates the genome-containing rAAV vector particles from the clarified, concentrated supernatant of a rAAV production cell culture. The process utilizes an affinity capture method performed at a high salt concentration followed by an anion exchange resin method performed at high pH to provide rAAV vector particles which are substantially free of rAAV intermediates.

公开(公告)号：US20230219075A1

公开(公告)日：2023-07-13

申请号：US17995639

申请日：2021-04-06

Applicant: Brown University

Inventor： KURT PENNELL ,  Chen Liu

IPC: B01J47/018 ,  B01J41/05 ,  B01J41/12 ,  B01J41/07 ,  B01D15/36 ,  C02F1/42 ,  C02F1/56 ,  C02F1/54

CPC classification number: B01J47/018 ,  B01J41/05 ,  B01J41/12 ,  B01J41/07 ,  B01D15/361 ,  C02F1/42 ,  C02F1/56 ,  C02F1/547 ,  C02F2001/422 ,  C02F2101/36

Abstract: This invention relates to an aqueous composition comprising, (a) an ion-exchange resin (IXR) comprising microporous beads having a particle size ranging from about 200 um to about 1000 um; (b) a water soluble surfactant having a molecular weight ranging from about 7,500 to about 15,000 Da; and (c) a buffer component; wherein the pH of the aqueous composition ranges from about 5 to about 8, and a process for isolating chemical contaminants using the aqueous composition.

公开(公告)号：US11649299B2

公开(公告)日：2023-05-16

申请号：US17344217

申请日：2021-06-10

Applicant: CYCLOLAB CYCLODEXTRIN RESEARCH AND DEVELOPMENT LABORATORY LTD.

Inventor： Tamas Sohajda ,  Gabriella Hirschbergne Szejtli ,  István Puskás

IPC: C08B37/16 ,  C08B37/00 ,  B01J39/05 ,  B01J41/05

CPC classification number: C08B37/0012 ,  B01J39/05 ,  B01J41/05 ,  C08B37/0003

Abstract: Present invention relates to a process to reduce butane sultone hydrolysis products (4-hydroxybutane-1-sulfonic acid, and bis(4-sulfobutyl) ether disodium) in sulfobutylether cyclodextrin reaction mixtures achieved with the combined use of a strong anion exchange resin having dialkyl 2-hydroxyethyl ammonium hydroxide functionality and a cation exchange resin.

公开(公告)号：US20190210003A1

公开(公告)日：2019-07-11

申请号：US15520390

申请日：2015-10-01

Applicant: JNC CORPORATION

Inventor： Natuki OKANIWA ,  Tsuyoshi NAKAMA ,  Eri IWAMOTO ,  Shuji SASAKI ,  Takuo IKEDA

IPC: B01J20/24 ,  B01J20/28 ,  B01J20/285 ,  B01J20/30 ,  B01D15/36 ,  B01J41/16 ,  B01J41/07 ,  C08B15/00 ,  C08B15/06 ,  C08J9/28 ,  B01J20/281

CPC classification number: B01J20/24 ,  B01D15/361 ,  B01J20/28042 ,  B01J20/281 ,  B01J20/285 ,  B01J20/30 ,  B01J20/305 ,  B01J20/3085 ,  B01J41/05 ,  B01J41/07 ,  B01J41/16 ,  B01J2220/52 ,  C07K1/16 ,  C07K1/18 ,  C08B15/005 ,  C08B15/06 ,  C08J9/26 ,  C08J9/28 ,  C08J2201/026 ,  C08J2301/12 ,  G01N30/482 ,  G01N30/88 ,  G01N2030/484

Abstract: Provided is a manufacturing method for monolithic structure that is a porous body formed of polysaccharide being a naturally-occurring polymer, has continuous pores with an average pore diameter suitable for biomolecule separation, and allows formation into arbitrary shape. The polysaccharide monolithic structure is manufactured by a method including a first step of obtaining a polysaccharide solution by dissolving polysaccharide into a mixed solvent of a first component and a second component at temperature lower than a boiling point of the mixed solvent, and a second step of obtaining polysaccharide monolithic structure by cooling the polysaccharide solution, wherein the first component is a solvent selected from lactate, and the second component is a solvent selected from water, lower alcohol, and a combination thereof. The monolithic structure obtained is a porous body having continuous pores with an average pore diameter of 0.01 to 20.0 micrometers, and a thickness of 100 micrometers or more.

公开(公告)号：US20180326323A1

公开(公告)日：2018-11-15

申请号：US15776838

申请日：2016-11-22

Applicant: DOW GLOBAL TECHNOLOGIES LLC ,  ROHM AND HAAS COMPANY

Inventor： Stephen Pease ,  Daryl J. Gisch ,  Collin H. Martin ,  Bianca F. Martins

IPC: B01D15/36 ,  C07C51/47

CPC classification number: B01D15/363 ,  B01J41/05 ,  C07C51/47 ,  C07C53/122 ,  C12P7/52

Abstract: A method for chromatographically separating propionic acid from a liquid feed mixture including propionic acid and a carbohydrate by passing the liquid feed mixture through a bed including a strong base anion exchange resin.

公开(公告)号：US10010829B2

公开(公告)日：2018-07-03

申请号：US15046621

申请日：2016-02-18

Applicant: Carbon Sink, Inc.

Inventor： Allen B. Wright ,  Klaus S. Lackner ,  Burton Wright ,  Matt Wallen ,  Ursula Ginster ,  Eddy J. Peters

IPC: B01D53/04 ,  B01D53/02 ,  B01D53/22 ,  B65G5/00 ,  B01D53/96 ,  B01D53/62 ,  B01D61/44 ,  B01D71/10 ,  B01D71/28 ,  B01D71/54 ,  B01D71/82 ,  B01J41/05

CPC classification number: B01D53/228 ,  B01D53/02 ,  B01D53/025 ,  B01D53/04 ,  B01D53/62 ,  B01D53/96 ,  B01D61/445 ,  B01D71/10 ,  B01D71/28 ,  B01D71/54 ,  B01D71/82 ,  B01D2252/1035 ,  B01D2253/206 ,  B01D2253/25 ,  B01D2253/34 ,  B01D2257/504 ,  B01D2258/06 ,  B01D2325/42 ,  B01J41/05 ,  B65G5/00 ,  Y02C10/04 ,  Y02C10/08

Abstract: The present invention is directed to methods for removing CO2 from air, which comprises exposing sorbent covered surfaces to the air. The invention also provides for an apparatus for exposing air to a CO2 sorbent. In another aspect, the invention provides a method and apparatus for separating carbon dioxide (CO2) bound in a sorbent.

公开(公告)号：US09963359B2

公开(公告)日：2018-05-08

申请号：US14763700

申请日：2014-01-27

Applicant: BROMINE COMPOUNDS LTD.

Inventor： Emanuel Korngold ,  Mordechai Cohen ,  Mira Bergstein Freiberg ,  Sharon Krumbein Rubin

IPC: C02F1/42 ,  B01J41/05 ,  C02F101/12 ,  C02F103/18

CPC classification number: C02F1/42 ,  B01J41/05 ,  C02F2001/422 ,  C02F2101/12 ,  C02F2103/18 ,  C02F2303/16 ,  C02F2303/185

Abstract: The invention relates to a process for recovering bromide from a halide-containing aqueous stream, comprising the steps of: providing a feed of halide-containing aqueous stream; contacting an anion-exchange resin with said feed, to form halide-loaded resin; treating said halide-loaded resin with a regenerant and subsequently with a rinse to produce, in succession, a chloride-rich solution, a mixed chloride/bromide solution, a bromide-rich solution and an essentially halide-free solution; directing said mixed chloride/bromide solution to said feed; processing said bromide-rich solution to recover one or more bromide products; and utilizing said essentially halide-free solution for regenerant dilution and/or rinsing of said resin. An apparatus for carrying out the process is also disclosed.

公开(公告)号：US20180116254A1

公开(公告)日：2018-05-03

申请号：US15793362

申请日：2017-10-25

Applicant: Red Bull GmbH

Inventor： Gunnar DEMOULIN ,  Roland CONCIN ,  Christian RINDERER

IPC: A23L3/02 ,  B01J39/05 ,  B01J39/18 ,  B01J41/05 ,  B01J41/12 ,  A23L3/3454

CPC classification number: A23L3/02 ,  A23L2/46 ,  A23L2/78 ,  A23L3/001 ,  A23L3/04 ,  A23L3/3454 ,  A23V2002/00 ,  B01J39/05 ,  B01J39/18 ,  B01J41/05 ,  B01J41/12 ,  C02F1/283 ,  C02F1/42 ,  C02F1/444 ,  C02F1/66 ,  C02F9/00 ,  C02F2001/422 ,  C02F2001/425 ,  C02F2103/32 ,  C02F2209/05 ,  C02F2209/06 ,  C02F2301/043

Abstract: The invention relates to a pasteurization plant and a method of operating a pasteurization plant. During operation of the pasteurization plant, a tempered process liquid is applied to containers filled with food products in one or more treatment zone(s). At least a part of the process liquid is fed back to the treatment zone(s) for reuse in at least one recirculation loop. At least a partial quantity of a volumetric flow of the process liquid fed per unit of time via the at least one recirculation loop is diverted to create at least one partial flow, circulated through at least one cleaning device and then returned to a recirculation loop or a treatment zone again. The at least one cleaning device comprises a membrane filtration device and an ion exchange device.

公开(公告)号：US09776892B2

公开(公告)日：2017-10-03

申请号：US14083945

申请日：2013-11-19

Applicant: Ovivo Luxembourg S.å.r.l.

Inventor： Dominique Gensbittel

IPC: C02F1/42 ,  B01J49/85 ,  B01D15/36 ,  B01J41/05 ,  B01J47/022 ,  B01J49/07 ,  C02F101/10 ,  C02F103/04

CPC classification number: C02F1/42 ,  B01D15/363 ,  B01J41/05 ,  B01J47/022 ,  B01J49/07 ,  B01J49/85 ,  C02F2001/422 ,  C02F2101/10 ,  C02F2101/108 ,  C02F2103/04 ,  C02F2301/08 ,  C02F2303/16

Abstract: A process is described for treating water, in particular for obtaining ultrapure water, in which a decationized water stream is passed at least through a first strong base anion exchange bed and a second strong base anion exchange bed, which is arranged downstream, in particular directly downstream, of the first strong base anion exchange bed. Furthermore, a water treatment system and a counter-current ion exchange unit for carrying out such a process are described.

公开(公告)号：US20170259255A1

公开(公告)日：2017-09-14

申请号：US15511184

申请日：2015-07-13

Applicant: NANJING UNIVERSITY ,  NANJING UNIVERSITY YANCHENG ENVIRONMENTAL PROTECTION TECHNOLOGY ANDENGINEERING RESEARCH INST

Inventor： Jinnan WANG ,  Yi WANG ,  Xin YANG ,  Cheng CHENG ,  Chen CHEN

IPC: B01J41/13 ,  C08F212/36 ,  C08F8/44

CPC classification number: B01J41/13 ,  B01J41/05 ,  B01J41/07 ,  C08F8/32 ,  C08F8/44 ,  C08F12/24 ,  C08F12/28 ,  C08F212/36 ,  C08F12/18 ,  C08F8/12 ,  C08F8/02

Abstract: The present disclosed are a high exchange-capacity anion exchange resin with dual functional-groups and method of synthesis thereof. The invention relates to the field of environmental function material synthesis and application. The resin is based on chloromethylated polystyrene-divinylbenzene polymer as matrix, and by primary amination and quaternization, yields an anion exchange resin with dual functional-groups having both a weak base anionic group and a strong base anionic group. The anion exchange resin not only has high adsorption capacity for water-born nitrate ions, but also can effectively squelch natural organic acids such as phytic acid in water, thus simultaneously removing nitrate ions and phytic acid organic matter from water. Therefore, the resin has a broad application potential in the fields of drinking water treatment, groundwater remediation, and advanced urban sewage treatment.