公开(公告)号：US20100056928A1

公开(公告)日：2010-03-04

申请号：US12538616

申请日：2009-08-10

Applicant: Karel ZUZAK ,  Jeffrey A. CADEDDU ,  Rafael UFRET-VINCENTY ,  Robert P. FRANCIS ,  Edward LIVINGSTON

Inventor： Karel ZUZAK ,  Jeffrey A. CADEDDU ,  Rafael UFRET-VINCENTY ,  Robert P. FRANCIS ,  Edward LIVINGSTON

IPC: A61B6/00 ,  G01J3/40

CPC classification number: A61B5/0059 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/0086 ,  A61B5/14551 ,  A61B5/4064 ,  A61B5/411 ,  A61B5/413 ,  A61B5/4842 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0229 ,  G01J3/0264 ,  G01J3/10 ,  G01J3/2803 ,  G01J3/2823 ,  G01J2003/1213 ,  G01J2003/1282 ,  G01N21/31 ,  G01N21/39

Abstract: A hyperspectral imaging system having an optical path. The system including an illumination source adapted to output a light beam, the light beam illuminating a target, a dispersing element arranged in the optical path and adapted to separate the light beam into a plurality of wavelengths, a digital micromirror array adapted to tune the plurality of wavelengths into a spectrum, an optical device having a detector and adapted to collect the spectrum reflected from the target and arranged in the optical path and a processor operatively connected to and adapted to control at least one of: the illumination source; the dispersing element; the digital micromirror array; the optical device; and, the detector, the processor further adapted to output a hyperspectral image of the target. The dispersing element is arranged between the illumination source and the digital micromirror array, the digital micromirror array is arranged to transmit the spectrum to the target and the optical device is arranged in the optical path after the target.

Abstract translation: 具有光路的高光谱成像系统。 该系统包括适于输出光束的照明源，照射目标的光束，布置在光路中并适于将光束分离成多个波长的分散元件，适于调谐多个的数字微镜阵列 具有检测器并且适于收集从目标反射并布置在光路中的光谱的光学装置，以及可操作地连接到并适于控制以下各项中的至少一个的处理器：照明源; 分散元件; 数字微镜阵列; 光学装置; 并且，所述检测器，所述处理器还适于输出所述目标的高光谱图像。 分散元件布置在照明源和数字微镜阵列之间，数字微镜阵列被布置成将光谱传输到目标，并且光学装置被布置在目标之后的光路中。

公开(公告)号：US07557924B2

公开(公告)日：2009-07-07

申请号：US11504120

申请日：2006-08-15

Applicant: Jon K. Nisper ,  Michael J. Mater

Inventor： Jon K. Nisper ,  Michael J. Mater

IPC: G01J3/51

CPC classification number: G01J3/28 ,  G01J3/0275 ,  G01J3/0289 ,  G01J3/10 ,  G01J3/50 ,  G01J3/501 ,  G01J3/51 ,  G01J3/513 ,  G01J3/524 ,  G01J2003/1282 ,  G01J2003/2866 ,  G01J2003/467

Abstract: An optical system comprising an optical instrument and a processing unit. The optical instrument may comprise an illumination source and a sensor. The processing unit may comprise a data storage having stored thereon a characterization of the illumination source and a characterization of the sensor. The processing unit may also comprise a computer configured to calculate a system response of the illumination source and the receiving element considering the characterization of the illumination source and the characterization of the receiving element.

Abstract translation: 一种光学系统，包括光学仪器和处理单元。 光学仪器可以包括照明源和传感器。 处理单元可以包括其上存储有照明源的表征和传感器的表征的数据存储器。 处理单元还可以包括计算机，其被配置为考虑照明源的特征和接收元件的表征来计算照明源和接收元件的系统响应。

公开(公告)号：US20070229821A1

公开(公告)日：2007-10-04

申请号：US11696005

申请日：2007-04-03

Applicant: Sean Christian ,  Jess Ford ,  Mike Ponstingl ,  Sven Kruger ,  Margaret Waid ,  Bryan Kasperski ,  Enrique Prati

Inventor： Sean Christian ,  Jess Ford ,  Mike Ponstingl ,  Sven Kruger ,  Margaret Waid ,  Bryan Kasperski ,  Enrique Prati

IPC: G01J3/28

CPC classification number: G01J3/08 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0297 ,  G01J3/28 ,  G01J3/42 ,  G01J2003/1282 ,  G01J2003/1286 ,  G01N21/274

Abstract: A spectroscope designed to utilize an adaptive optical element such as a micro mirror array (MMA) and two distinct light channels and detectors. The devices can provide for real-time and near real-time scaling and normalization of signals.

Abstract translation: 设计用于利用诸如微镜阵列（MMA）和两个不同的光通道和检测器的自适应光学元件的分光镜。 这些设备可以提供信号的实时和近乎实时的缩放和归一化。

公开(公告)号：US07106511B2

公开(公告)日：2006-09-12

申请号：US10791449

申请日：2004-03-02

Applicant: Annette C. Grot ,  Shalini Venkatesh

Inventor： Annette C. Grot ,  Shalini Venkatesh

IPC: G02B5/18 ,  H04N9/04 ,  G01J3/28

CPC classification number: G01J3/32 ,  G01J3/10 ,  G01J3/18 ,  G01J2003/1282

Abstract: An optical imaging system and method for achieving a large depth of field without decreasing the relative aperture of an imaging lens. The imaging system has a light source for sequentially illuminating an object to be imaged with light of different ones of a plurality of wavelengths, and an imaging lens that has a focal length that varies with the wavelength of the light that illuminates the object. For each wavelength of light by which the object is illuminated, the imaging lens will image a different object plane onto an image receiving unit, and the image receiving unit will capture one well-focused, high resolution image of the object.

Abstract translation: 一种用于在不减小成像透镜的相对孔径的情况下实现大景深的光学成像系统和方法。 成像系统具有光源，用于使用多个波长的不同光的光顺序地照射待成像的物体，以及具有随着照射物体的光的波长而变化的焦距的成像透镜。 对于被照射物体的每个波长的波长，成像透镜将不同的物体平面成像到图像接收单元上，并且图像接收单元将捕获对象的一个​​精心集中的高分辨率图像。

公开(公告)号：US20050270524A1

公开(公告)日：2005-12-08

申请号：US11096448

申请日：2005-04-01

Applicant: David Wang ,  James Hendrix ,  Adam Norton

Inventor： David Wang ,  James Hendrix ,  Adam Norton

IPC: G01J3/02 ,  G01J3/10 ,  G01J3/12 ,  G01J3/14 ,  G01J3/18 ,  G01J3/28 ,  G01N21/47 ,  G01N21/55 ,  G01N21/95 ,  G01N21/956

CPC classification number: G01N21/55 ,  G01J3/02 ,  G01J3/0229 ,  G01J3/14 ,  G01J3/18 ,  G01J2003/1213 ,  G01J2003/1282 ,  G01N21/4788 ,  G01N21/9501 ,  G01N21/956

Abstract: An optical filter for the selective attenuation of specific wavelengths of light includes at least one spectrally dispersive element, such as a diffraction grating or prism, in combination with an optical filter. A dispersive element separates broadband light into a constituent wavelength spread in angle space. An optical filter, or filter array, can block and/or attenuate specific wavelengths or wavelength ranges of interest while the light is angularly dispersed. A second dispersive element can recombine this filtered, separated wavelength fan of light into a coaxial broadband beam having a smoother intensity profile than the unfiltered beam.

Abstract translation: 用于特定波长的光的选择性衰减的滤光器包括与滤光器组合的至少一个光谱色散元件，例如衍射光栅或棱镜。 分散元件将宽带光分成在角度空间中扩散的构成波长。 光学滤波器或滤波器阵列可以在光被角度地分散时阻挡和/或衰减特定的波长或波长范围。 第二分散元件可以将该经过滤波的分离的波长风扇重新组合成具有比未滤波光束更平滑的强度分布的同轴宽带光束。

公开(公告)号：US20050195483A1

公开(公告)日：2005-09-08

申请号：US10791449

申请日：2004-03-02

Applicant: Annette Grot ,  Shalini Venkatesh

Inventor： Annette Grot ,  Shalini Venkatesh

IPC: G02B21/06

CPC classification number: G01J3/32 ,  G01J3/10 ,  G01J3/18 ,  G01J2003/1282

Abstract: An optical imaging system and method for achieving a large depth of field without decreasing the relative aperture of an imaging lens. The imaging system has a light source for sequentially illuminating an object to be imaged with light of different ones of a plurality of wavelengths, and an imaging lens that has a focal length that varies with the wavelength of the light that illuminates the object. For each wavelength of light by which the object is illuminated, the imaging lens will image a different object plane onto an image receiving unit, and the image receiving unit will capture one well-focused, high resolution image of the object.

Abstract translation: 一种用于在不减小成像透镜的相对孔径的情况下实现大景深的光学成像系统和方法。 成像系统具有光源，用于使用多个波长的不同光的光顺序地照射待成像的物体，以及具有随着照射物体的光的波长而变化的焦距的成像透镜。 对于被照射物体的每个波长的波长，成像透镜将不同的物体平面成像到图像接收单元上，并且图像接收单元将捕获对象的一个​​精心集中的高分辨率图像。

公开(公告)号：US06867919B2

公开(公告)日：2005-03-15

申请号：US10681016

申请日：2003-10-08

Applicant: Volker Seyfried

Inventor： Volker Seyfried

IPC: G01J3/12 ,  G02B21/00 ,  G02B27/28 ,  G02B27/10 ,  G01N21/00 ,  G02B21/06 ,  G02B27/40

CPC classification number: G02B27/283 ,  G01J3/0229 ,  G01J2003/1282 ,  G02B21/0068

Abstract: An optical arrangement for directing illumination light to a sample and for directing the detection light proceeding from the sample to a detector has a spectrally selective influencing means in the beam path of the detection light, which influences the polarization properties of the illumination light reflected or scattered from the sample in such a way that a polarizing beam splitter splits the illumination light reflected or scattered from the sample out of the detection light.

Abstract translation: 用于将照明光引导到样品并用于将从样品引导到检测器的检测光的光学装置在检测光的光束路径中具有光谱选择性影响装置，其影响反射或散射的照明光的偏振特性 从偏振光束分离器将样品反射或散射的照明光分离出检测光。

公开(公告)号：US06825930B2

公开(公告)日：2004-11-30

申请号：US10163233

申请日：2002-06-04

Applicant: Paul J. Cronin ,  Daniel Orband ,  Stephen D. Fantone ,  Peter J. Miller

Inventor： Paul J. Cronin ,  Daniel Orband ,  Stephen D. Fantone ,  Peter J. Miller

IPC: F21V900

CPC classification number: G01J3/10 ,  G01J3/2823 ,  G01J2003/1282 ,  G01N21/255 ,  G01N2201/062 ,  G01N2201/0633 ,  G01N2201/0635 ,  G01N2201/0638

Abstract: The invention features a multi-spectral microscopy system for illuminating a sample with light of a selectable spectral content and generating an image of the sample in response to the illumination. The multi-spectral microscopy system includes a multispectral illuminator that provides output radiation having the selectable spectral content. A preferred set of optical arrangements for the multispectral illuminator generates the output radiation so that the spectral content of the output radiation is substantially uniform across its transverse profile. Furthermore, the multispectral illuminator can include monitoring optics and a corresponding detector array that independently monitors the output in each spectral band of the radiation produced by the multispectral illuminator. The monitoring provides calibration, feedback, and/or source aging information to insure robust and reliable performance for the multispectral illuminator. The multi-spectral microscopy system also includes a microscope which illuminates the sample with light derived from the output of the multispectral illuminator, and beam modification optics, which modify the output from the lamp prior to the microscope to increase the light efficiency of the microscope and fully exploit field of view and resolution of the microscope.

Abstract translation: 本发明的特征在于一种多光谱显微镜系统，用于利用可选光谱含量的光照射样品，并响应于照明产生样品的图像。 多光谱显微镜系统包括多光谱照明器，其提供具有可选光谱含量的输出辐射。 用于多光谱照明器的优选的一组光学装置产生输出辐射，使得输出辐射的光谱含量在其横向轮廓上基本上是均匀的。 此外，多光谱照明器可以包括监视光学器件和相应的检测器阵列，其独立地监视由多光谱照明器产生的辐射的每个光谱带中的输出。 监控提供校准，反馈和/或源老化信息，以确保多光谱照明器的稳健可靠的性能。 多光谱显微镜系统还包括用来自多光谱照明器的输出的光照射样品的显微镜以及在显微镜之前改变来自灯的输出的光束修改光学器件，以提高显微镜的光效率， 充分利用显微镜的视野和分辨率。

公开(公告)号：US20040070835A1

公开(公告)日：2004-04-15

申请号：US10681016

申请日：2003-10-08

Applicant: Leica Microsystems Heidelberg GmbH

Inventor： Volker Seyfried

IPC: G02B027/10

CPC classification number: G02B27/283 ,  G01J3/0229 ,  G01J2003/1282 ,  G02B21/0068

Abstract: An optical arrangement for directing illumination light to a sample and for directing the detection light proceeding from the sample to a detector has a spectrally selective influencing means in the beam path of the detection light, which influences the polarization properties of the illumination light reflected or scattered from the sample in such a way that a polarizing beam splitter splits the illumination light reflected or scattered from the sample out of the detection light.

Abstract translation: 用于将照明光引导到样品并用于将从样品引导到检测器的检测光的光学装置在检测光的光束路径中具有光谱选择性影响装置，其影响反射或散射的照明光的偏振特性 从偏振光束分离器将样品反射或散射的照明光分离出检测光。

公开(公告)号：US20010052977A1

公开(公告)日：2001-12-20

申请号：US09783206

申请日：2001-02-15

Applicant: SAITAMA UNIVERSITY

Inventor： Satoru Toyooka

IPC: G01J003/12

CPC classification number: G01J3/12 ,  G01J3/2823 ,  G01J2003/1278 ,  G01J2003/1282

Abstract: An imaging spectral device for use in the spectrum image analysis for performing the spectroscopic analysis of the respective points in two dimensional field is disclosed. The device comprises an imaging spectral device composing a white-light source to illuminate an object to be measured, a tunable filter located in the optical path between the object and the white-light source, a driving mechanism for wavelength scanning of the tunable filter, and a control unit in which scanning rate of transmitting wavelength of the tunable filter is controlled by the above-mentioned driving mechanism in such a manner that the spectral transmittance of the tunable filter integrated within the exposure time becomes desired spectral distribution of the object to be measured.

Abstract translation: 公开了用于在二维场中进行各点的光谱分析的光谱图像分析中使用的成像光谱装置。 该装置包括构成白光源以照射待测物体的成像光谱装置，位于物体与白光源之间的光路中的可调滤光器，可调滤光器的波长扫描驱动机构， 以及控制单元，其中可调谐滤波器的发射波长的扫描速率由上述驱动机构控制，使得在曝光时间内积分的可调滤波器的分光透射率成为所要对象的所需光谱分布 测量。