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公开(公告)号:US11139156B2
公开(公告)日:2021-10-05
申请号:US15555888
申请日:2016-03-07
Applicant: Micromass UK Limited
Inventor: Julia Balog , Tamas Karancsi , Steven Derek Pringle , Zoltan Takats , James Kinross , Jeremy K Nicholson
IPC: A61B10/02 , H01J49/04 , A61B17/32 , A61B18/00 , A61B18/14 , A61B18/20 , G01N3/00 , G01N9/00 , G01N33/68 , H01J49/00 , H01J49/06 , H01J49/16 , A61B90/13 , A61B1/04 , A61B1/273 , A61B5/00 , A61B5/01 , A61B5/0507 , A61B5/055 , A61B6/03 , A61B8/13 , A61B10/00 , A61B17/00 , A61B18/04 , A61B18/18 , A61F13/38 , C12Q1/02 , C12Q1/04 , C12Q1/18 , C12Q1/24 , G01N1/22 , G01N27/622 , G01N27/624 , G01N30/72 , G01N33/487 , G01N33/92 , H01J49/02 , H01J49/10 , H01J49/14 , H01J49/24 , H01J49/26 , G16B20/00 , G16H10/40 , G16H15/00 , G16H50/20 , A61B1/00 , A61B1/31 , A61B5/145
Abstract: An apparatus is disclosed including a tool comprising a first device for generating aerosol from a target, the first device being deployed through an opening in a tubing of the tool, wherein the tubing is provided with aspiration ports or fenestrations such that the generated aerosol is aspirated into the tubing via the aspiration ports or fenestrations. The aspirated aerosol is then transferred to a mass spectrometer for subsequent mass analysis.
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公开(公告)号:US20210296108A1
公开(公告)日:2021-09-23
申请号:US16330640
申请日:2016-10-11
Applicant: SHIMADZU CORPORATION
Inventor: Yusuke TATEISHI , Yoshihiro UENO , Shinji MIYAUCHI
Abstract: An ion guide (222) is for use in transport of an ion incident from an upstream side toward a downstream side. The ion guide includes 2n rod electrodes (n is an integral number greater than or equal to 2) equally spaced and surrounding an ion optical axis (C) that is a central axis of a flight path of the ion, a voltage applying unit (30) that applies a radio-frequency voltage to the 2n rod electrodes, and a controller (43) that controls the voltage applying unit (30). The controller (43) prompts the voltage applying unit (30) to apply a radio-frequency voltage that generates, in a space surrounded by the 2n rod electrodes, an electric field which is a 2n-multipole electric field superimposed by a higher-order electric field component than the 2n-multipole electric field.
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公开(公告)号:US20210262991A1
公开(公告)日:2021-08-26
申请号:US17174622
申请日:2021-02-12
Applicant: Elemental Scientific, Inc.
Inventor: Jacob Unnerstall , Patrick Sullivan , Daniel R. Wiederin , Brad Prucha , Charles Derrick Quaries, JR. , Jae Seok Lee
Abstract: Systems and methods are described to provide speciation of silicon species present in a remote sample for analysis. A method embodiment includes, but is not limited to, receiving a fluid sample containing inorganic silicon in the presence of bound silicon from a remote sampling system via a fluid transfer line; transferring the fluid sample to an inline chromatographic separation system; separating the inorganic silicon from the bound silicon via the inline chromatographic separation system; transferring the separated inorganic silicon and bound silicon to a silicon detector in fluid communication with the inline chromatographic separation system; and determining an amount of one or more of the inorganic silicon or the bound silicon in the fluid sample via the silicon detector.
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公开(公告)号:US11081329B2
公开(公告)日:2021-08-03
申请号:US15555758
申请日:2016-03-07
Applicant: Micromass UK Limited
Inventor: Emrys Jones , Tamas Karancsi , Steven Derek Pringle , Julia Balog , Daniel Simon , Lajos Godorhazy , Daniel Szalay , Zoltan Takats
IPC: H01J49/00 , H01J49/04 , A61B10/02 , A61B17/32 , A61B18/00 , A61B18/14 , A61B18/20 , G01N3/00 , G01N9/00 , G01N33/68 , H01J49/06 , H01J49/16 , A61B90/13 , A61B1/04 , A61B1/273 , A61B5/00 , A61B5/01 , A61B5/0507 , A61B5/055 , A61B6/03 , A61B8/13 , A61B10/00 , A61B17/00 , A61B18/04 , A61B18/18 , A61F13/38 , C12Q1/02 , C12Q1/04 , C12Q1/18 , C12Q1/24 , G01N1/22 , G01N27/622 , G01N27/624 , G01N30/72 , G01N33/487 , G01N33/92 , H01J49/02 , H01J49/10 , H01J49/14 , H01J49/24 , H01J49/26 , G16B20/00 , G16H10/40 , G16H15/00 , G16H50/20 , A61B1/00 , A61B1/31 , A61B5/145 , G06F19/00
Abstract: A method of mass spectrometry or ion mobility spectrometry is disclosed comprising: providing an analyte; supplying a matrix compound to said analyte such that said analyte dissolves in said matrix; forming first droplets of the dissolved analyte; and colliding said first droplets with a collision surface. The use of matrix improves the analyte ion signal.
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公开(公告)号:US11056327B2
公开(公告)日:2021-07-06
申请号:US16383629
申请日:2019-04-14
Applicant: PERKINELMER HEALTH SCIENCES CANADA, INC.
Inventor: Tak Shun Cheung , Chui Ha Cindy Wong , Hamid Badiei , William Fisher
Abstract: Certain configurations of systems and methods that can detect inorganic ions and organic ions in a sample are described. In some configurations, the system may comprise one, two, three or more mass spectrometer cores. In some instances, the mass spectrometer cores can utilize common components such as gas controllers, processors, power supplies and vacuum pumps. In certain configurations, the systems can be designed to detect both inorganic and organic analytes comprising a mass from about three atomic mass units, four atomic mass units or five atomic mass units up to a mass of about two thousand atomic mass units.
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公开(公告)号:US20210148858A1
公开(公告)日:2021-05-20
申请号:US17043406
申请日:2019-08-29
Applicant: IAS INC.
Inventor: Katsuhiko KKAWABATA , Tatsuya ICHINOSE , Kohei NiISHIGUCHI
IPC: G01N27/623 , G01N27/626 , H01J49/00 , H01J49/04 , H01J49/10
Abstract: The present invention provides a method for analyzing a sample containing metal fine particles with an inductive coupling plasma mass spectrometer. The method enables analysis of the sample without the need of standard metal fine particles. Specifically, the present invention relates to a method for analyzing metal fine particles in liquid by use of an inductive coupling plasma mass spectrometer. In the method, the analysis apparatus is provided with a standard solution introduction apparatus including a standard solution storage unit for storing a standard solution containing a specific element in a known concentration, a syringe pump for suctioning and discharging the standard solution, and a solution introduction unit having a standard solution nebulizer and a standard solution spray chamber that are supplied with the standard solution, the standard solution is directly supplied to the standard solution nebulizer at a flow rate of 3 μL/min or less.
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公开(公告)号:US20210116402A1
公开(公告)日:2021-04-22
申请号:US17129444
申请日:2020-12-21
Applicant: Ionwerks, Inc.
Inventor: J. Albert Schultz , Thomas F. Egan , Ernest K. Lewis , Steven Ulrich , Kelley L. Waters
IPC: G01N23/2258 , H01J49/04 , H01J49/14 , H01J49/16 , H01J49/00 , G01N21/64 , H01J49/26 , H01J49/40 , G01N21/65 , H01J49/10
Abstract: Methods and devices for mass spectrometry are described, specifically the use of nanoparticulate implantation as a matrix for secondary ion and more generally secondary particles. A photon beam source or a nanoparticulate beam source can be used a desorption source or a primary ion/primary particle source.
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公开(公告)号:US10985003B2
公开(公告)日:2021-04-20
申请号:US16830487
申请日:2020-03-26
Applicant: China University of Geosciences, Wuhan
Inventor: Zhaochu Hu , Tao He , Wen Zhang , Haihong Chen , Ming Li , Yongsheng Liu
Abstract: The present invention provides an analysis method for determining halogens in geological samples by ICP-MS. The method includes following steps: weighing a geological sample and ammonium bifluoride in a sample dissolving tank, tightening the sample dissolving tank, and shaking; then heating the sample dissolving tank in a drying oven, and setting a temperature of the drying oven as 200-220° C. and heating time as 1-2 hours; cooling the sample dissolving tank to room temperature so as to obtain a solid mixture after heating is ended, adding ammonium hydroxide into the solid mixture, centrifuging, removing a precipitate, and collecting the supernatant; adding an internal standard solution into the supernatant, and uniformly mixing; and optimizing the ICP-MS to an optimal state, testing content of chlorine in the supernatant under a condition of medium resolution m/Δm=4000, and testing content of bromine and iodine in the supernatant under a condition of low resolution m/Δm=300.
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公开(公告)号:US10978284B2
公开(公告)日:2021-04-13
申请号:US15556037
申请日:2016-03-07
Applicant: Micromass UK Limited
Inventor: Steven Derek Pringle , Michael Raymond Morris , Julia Balog , Emrys Jones , Keith Richardson , James Ian Langridge , Daniel Simon , Lajos Godorhazy , Daniel Szalay , Zoltan Takats
IPC: H01J49/00 , H01J49/04 , A61B10/02 , A61B18/14 , A61B18/20 , G01N33/68 , H01J49/06 , H01J49/16 , G16H30/40 , A61B90/00 , A61B8/08 , G16C20/20 , G16H30/20 , A61B34/20 , A61B90/13 , A61B1/04 , A61B1/273 , A61B5/00 , A61B5/01 , A61B5/0507 , A61B5/055 , A61B6/03 , A61B10/00 , A61B17/00 , A61B18/00 , A61B18/04 , A61B18/18 , A61F13/38 , C12Q1/02 , C12Q1/04 , C12Q1/18 , C12Q1/24 , G01N1/22 , G01N3/00 , G01N9/00 , G01N27/622 , G01N27/624 , G01N30/72 , G01N33/487 , G01N33/92 , H01J49/02 , H01J49/10 , H01J49/14 , H01J49/24 , H01J49/26 , G16B20/00 , A61B34/30 , A61B18/12 , A61B17/32 , G16H10/40 , G16H15/00 , G16H50/20 , A61B1/00 , A61B1/31 , A61B5/145 , A61B8/13 , G06F19/00
Abstract: A method is disclosed comprising obtaining or acquiring image or other data from one or more regions of a target using an imaging sensor. The image or other data may then be used to determine one or more regions of interest of the target. An ambient ionisation ion source may then be used to generate aerosol, smoke or vapour from one or more regions of the target.
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公开(公告)号:US10971346B2
公开(公告)日:2021-04-06
申请号:US16662881
申请日:2019-10-24
Applicant: Micromass UK Limited
Inventor: Tamas Karancsi , Lajos Godorhazy , Daniel Szalay , Zoltan Takats , Julia Balog , Steven Derek Pringle , Daniel Simon
IPC: H01J49/00 , H01J49/04 , A61B10/02 , A61B17/32 , A61B18/00 , A61B18/14 , A61B18/20 , G01N3/00 , G01N9/00 , G01N33/68 , H01J49/06 , H01J49/16 , A61B90/13 , A61B1/04 , A61B1/273 , A61B5/00 , A61B5/01 , A61B5/0507 , A61B5/055 , A61B6/03 , A61B8/13 , A61B10/00 , A61B17/00 , A61B18/04 , A61B18/18 , A61F13/38 , C12Q1/02 , C12Q1/04 , C12Q1/18 , C12Q1/24 , G01N1/22 , G01N27/622 , G01N27/624 , G01N30/72 , G01N33/487 , G01N33/92 , H01J49/02 , H01J49/10 , H01J49/14 , H01J49/24 , H01J49/26 , G16B20/00 , G16H70/00 , G16H20/00 , G16H10/40 , G16H15/00 , G16H50/20 , A61B1/00 , A61B1/31 , A61B5/145 , G06F19/00
Abstract: An apparatus for mass spectrometry and/or ion mobility spectrometry is disclosed comprising a first device arranged and adapted to generate aerosol, smoke or vapour from a target and one or more second devices arranged and adapted to aspirate aerosol, smoke, vapour and/or liquid to or towards an analyser. A liquid trap or separator is provided to capture and/or discard liquid aspirated by the one or more second devices.
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