公开(公告)号：US20190250182A1

公开(公告)日：2019-08-15

申请号：US16376069

申请日：2019-04-05

Applicant: Abbott Laboratories

Inventor： Robert Luoma

IPC: G01N35/04 ,  G01N35/02

CPC classification number: G01N35/04 ,  G01N35/021 ,  G01N35/025 ,  G01N2035/0408 ,  G01N2035/0443

Abstract: A diagnostic analyzer includes a rotating device, a first optical reader, and a second optical reader. The rotating device includes a first darkened compartment, a second darkened compartment, and an optical path along which the first darkened compartment and the second darkened compartment travel. The first optical reader is operable to read the first darkened compartment and the second optical reader is operable to read the second darkened compartment.

公开(公告)号：USD854182S1

公开(公告)日：2019-07-16

申请号：US29531460

申请日：2015-06-25

Applicant: Abbott Laboratories

Designer： Roger W. Accurso

公开(公告)号：US10345218B2

公开(公告)日：2019-07-09

申请号：US15832329

申请日：2017-12-05

Applicant: Abbott Laboratories

Inventor： Svitlana Y. Berezhna ,  Rene Nieves Alicea ,  Kam Lin Wong ,  Damian John Verdnik ,  Leigh Whiting ,  Mahmoud Janbakhsh

IPC: G06K9/00 ,  G01N15/14 ,  G01N15/02 ,  G06T7/00 ,  G06T7/11 ,  G06K9/46 ,  G01N15/00 ,  G01N15/10

Abstract: The present disclosure provides methods for automated slide assessments made in conjunction with digital image-based microscopy. Automated methods of acquiring patient information and specimen information from prepared slides, and digitally linking such information into patient-tagged specimen data, are provided. Also provided are methods that include automatically identifying an optimal area for morphological assessment of a blood smear on a hematological slide, including methods for triggering the analysis of such an area, e.g., using an automated digital image-based hematology system. The present disclosure also provides devices, systems and computer readable media for use in performing processes of the herein described methods.

公开(公告)号：US10342244B2

公开(公告)日：2019-07-09

申请号：US15829142

申请日：2017-12-01

Applicant: ABBOTT LABORATORIES

Inventor： Bridget Barrett-Reis ,  Pamela T. Price ,  Amy Mackey

IPC: A23L2/66 ,  G01N33/82 ,  A23L33/00 ,  A23L33/10 ,  A23L33/115 ,  A23L33/17

Abstract: Disclosed are infant formulas and corresponding methods of using them to promote retinal health and vision development in infants. The formulas, which are free of egg phospholipids and comprise fat, protein, carbohydrate, vitamins, and minerals, including docosahexaenoic acid and, on a ready-to-feed basis, at least about 50 mcg/liter of lutein, wherein the weight ratio of lutein (mcg) to docosahexaenoic acid (mg) is from about 1:2 to about 10:1. The formulas are also believed to be especially useful in reducing the risk of retinopathy of prematurity in preterm infants.

公开(公告)号：US10316353B2

公开(公告)日：2019-06-11

申请号：US14882109

申请日：2015-10-13

Applicant: ABBOTT LABORATORIES ,  TOKYO INSTITUTE OF TECHNOLOGY

Inventor： Ken Komiya ,  Makoto Komori ,  Toru Yoshimura

IPC: C12Q1/68 ,  C07H21/04 ,  C12Q1/682 ,  C12Q1/6844 ,  C07K16/00

Abstract: Disclosed are methods for detecting a target nucleic acid in a sample. The methods include contacting said sample, in the presence of a polymerase and an endonuclease, with a sequence conversion oligonucleotide. Also disclosed are methods for detecting a target nucleic acid in a sample in which said sample is contacted, in the presence of a polymerase and an endonuclease, with a sequence conversion oligonucleotide and a signal amplifier oligonucleotide. The disclosure also provides compositions and kits comprising such sequence conversion and signal amplifier oligonucleotides.

公开(公告)号：US10274413B2

公开(公告)日：2019-04-30

申请号：US15348817

申请日：2016-11-10

Applicant: Abbott Laboratories

Inventor： John F. Heanue ,  Stuart L. Friedman

IPC: G01N15/14 ,  G02B27/09 ,  G01N15/10

Abstract: In some aspects, a flow cytometer system is provided that includes beam shaping optics positioned to manipulate a light beam and produce a resulting light beam that irradiates the core stream at the interrogation zone of the flow cell. The beam shaping optics include an acylindrical lens positioned to receive and focus light in a direction of a first axis orthogonal to a direction of light travel, and a cylindrical lens positioned to receive the light output from the acylindrical lens and to focus the light output from the acylindrical lens in a direction of a second axis orthogonal to the first axis and to the direction of light travel. The resulting light beam output has a flat-top shaped intensity profile along the first axis, and a Gaussian-shaped intensity profile along the second axis. Related methods of shaping a light beam at an interrogation zone of a flow cell are also provided.

公开(公告)号：US10274406B2

公开(公告)日：2019-04-30

申请号：US15905383

申请日：2018-02-26

Applicant: Abbott Laboratories

Inventor： Abe S. Mamaghani ,  Koshy T. Chacko ,  Rupa Rao ,  Rene Nieves Alicea

IPC: G01N1/31 ,  G01N1/30

Abstract: The present disclosure provides methods for carrying out Romanowsky-type stains, specifically Wright-Giemsa and May-Grünwald stains, quickly and efficiently. The methods greatly reduce the overall amount of time required to complete a Wright-Giemsa stain or a May-Grünwald stain of sufficient quality on a biological sample. The subject methods can be applied to both manual and automated staining procedures.

公开(公告)号：US20190041299A1

公开(公告)日：2019-02-07

申请号：US16059447

申请日：2018-08-09

Applicant: Abbott Laboratories

Inventor： John Scott Shoffner ,  Koshy T. Chacko ,  Roei Solomon

IPC: G01N1/28 ,  G01N1/31 ,  B05C13/02 ,  B05D3/00 ,  G01N35/00 ,  B60T15/00

Abstract: An automated smear making apparatus used to prepare and smear samples on glass slides. In one embodiment, there is provided a smearing subsystem that generally includes a smear cartridge having: an input reel; at least one roll bar; a take-up reel; and a smearing tape. The smearing tape is initially wound within the input reel and coupled to the take-up reel such that the smearing tape can be drawn from the input reel and into the take-up reel. The smearing tape may include a plurality of perforations formed therein. The smearing tape may then be wrapped around the roll bar such that each of the plurality of perforations forms a blade that extends from the smearing tape to expose a smear surface as the smearing tape is drawn into the take-up reel. Alternatively, the smearing tape may be bent such that an edge of the smearing tape forms a smear surface between two roll bars. A slide transport surface is also provided to move a slide across the smear surface.

公开(公告)号：US10191072B2

公开(公告)日：2019-01-29

申请号：US14731060

申请日：2015-06-04

Applicant: Abbott Laboratories

Inventor： Cordell Kay Gomm ,  Robert Paul Luoma, II ,  David Charles Arnquist ,  Ryan Patrick Johnson

IPC: G01N35/00 ,  G01N35/02 ,  G01N35/04

Abstract: A handling device for samples and reagents to be used in testing in a system. Carriers of samples and reagents are loaded on a platform which detects the presence of, and proper loading of, such carriers. The carriers are moved from the platform by a transporter to a bar code reader for identification. A reagent container is rotated during reading to facilitate identification. The transporter further moves identified reagent carriers to a carousel on which the carriers automatically secured for storage awaiting use in testing. The carousel rotates, and selected reagent containers rotate on the rotating carousel, during storage.

公开(公告)号：US20190004041A1

公开(公告)日：2019-01-03

申请号：US16057818

申请日：2018-08-08

Applicant: ABBOTT LABORATORIES

Inventor： Barry L. DOWELL ,  Susan GAYDA ,  Qiaoqiao RUAN ,  Joseph P. SKINNER ,  Sergey Y. TETIN

IPC: G01N33/543 ,  G01N33/53

Abstract: Provided herein are assays and kits useful for avoiding “prozone phenomenon” or “hook effect” and which expand the range of accurately measurable analyte concentrations.