公开(公告)号：US20220308125A1

公开(公告)日：2022-09-29

申请号：US17656761

申请日：2022-03-28

Applicant: Northeastern University

Inventor： Nian-Xiang Sun ,  Neville Sun ,  Xianfeng Lian ,  Huaihao Chen

IPC: G01R33/028 ,  H03H9/135

Abstract: A solidly mounted resonator (SMR)-based magnetoelectric (ME) antenna comprises a substrate, a Bragg reflector disposed on the substrate, a magnetostrictive/piezoelectric ME composite element disposed on the Bragg reflector, a first electrically conductive contact and a second electrically conductive contact. The first contact is disposed between the Bragg reflector and the magnetostrictive/piezoelectric ME composite element and electrically coupled to a bottom surface of the magnetostrictive/piezoelectric ME composite element. The second contact is disposed on top of the magnetostrictive/piezoelectric ME composite element and electrically coupled to the top of the magnetostrictive/piezoelectric ME composite element. The magnetostrictive/piezoelectric ME composite element comprises a magnetorestrictive multilayer deposited on a piezoelectric layer. The magnetorestrictive multilayer produces an in-plane uniaxial magnetic anisotropy (UMA). The UMA is a twofold UMA that exhibits a symmetric radiation pattern.

公开(公告)号：US20220299578A1

公开(公告)日：2022-09-22

申请号：US17698835

申请日：2022-03-18

Applicant: MERSEN USA EP CORP. ,  Northeastern University

Inventor： Roy A. Ball ,  Jonathan C. Kim

IPC: G01R31/40 ,  H02J3/38 ,  G01R31/52

Abstract: Pink noise analysis, along with unique properties of the photovoltaic (PV) operating point of both the instantaneous current and voltage signal, is used to distinguish arc faults from other noisy loads or PV degradations.

公开(公告)号：US20220273540A1

公开(公告)日：2022-09-01

申请号：US17695166

申请日：2022-03-15

Applicant: Northeastern University

Inventor： Jeffrey N. Agar

IPC: A61K8/49 ,  A61K8/58 ,  A61K8/65 ,  A61K47/22 ,  A61Q3/02 ,  A61Q5/00 ,  C08F283/06 ,  C08F289/00 ,  C08G75/06 ,  C09D1/00 ,  C09D171/02 ,  C09D181/02 ,  C09D189/00 ,  C12N11/08 ,  C25D11/00

Abstract: Disclosed are polymers, methods of making polymers, and compositions, focused on cross-linking heterocycles comprising a moiety of Formula I with thiols and thiolates.

公开(公告)号：US11427878B2

公开(公告)日：2022-08-30

申请号：US16897950

申请日：2020-06-10

Applicant: Northeastern University

Inventor： Xiangtao Deng ,  Zhaodong Wang ,  Hao Wu ,  Tianliang Fu ,  Yong Tian ,  Jiadong Li

IPC: C22C38/04 ,  C21D8/02 ,  C21D1/02 ,  C21D1/18 ,  C22C38/02 ,  C22C38/06 ,  C22C38/08 ,  C22C38/20 ,  C22C38/22 ,  C22C38/24 ,  C22C38/32

Abstract: An ultrahigh-strength ultrahigh-toughness and low-density dual-phase lamellar steel plate is disclosed. The steel plate comprises the following alloy components in percentage by mass: 0.200-0.320% of C, 0.600-2.000% of Mn, 0.200-0.600% of Si, 2.000-4.000% of Al, 0.300-1.200% of Ni, 0.001-0.005% of B, P not greater than 0.012%, S not greater than 0.005%, and the balance of Fe and inevitable impurities. The steel plate consists of dual phases of ferrites and martensites, the ferrites are high-temperature delta ferrites, the martensites are lath martensites, the delta ferrites are distributed in the lath martensites in a lamellar mode. The steel plate has excellent mechanical properties, for example, the yield strength in the rolling direction is not less than 1000 MPa, the tensile strength is not less than 1600 MPa, the elongation is not less than 8.0%, and the average value of Charpy V-Notch impact energy at −40° C. is not less than 350J.

公开(公告)号：US11414548B2

公开(公告)日：2022-08-16

申请号：US16749400

申请日：2020-01-22

Applicant: Northeastern University

Inventor： Ming Su

IPC: C08L83/04 ,  C08L1/00 ,  C08K3/08 ,  C08J5/18 ,  A61B6/10 ,  G21F1/10

Abstract: Disclosed is a composite material, comprising a polymer, a plurality of metal nanoparticles, and a surface-modifying agent (e.g., nanocellulose). Also disclosed is a method for shielding a subject from electromagnetic radiation, comprising placing one or more composite materials between the subject and a source of electromagnetic radiation, thereby reducing a dose of electromagnetic radiation received by the subject.

公开(公告)号：US11406737B2

公开(公告)日：2022-08-09

申请号：US16109455

申请日：2018-08-22

Applicant: Northeastern University

Inventor： Jonathan R. Soucy ,  Ehsan Shirzaei Sani ,  Abigail N. Koppes ,  Ryan A. Koppes ,  Nasim Annabi

IPC: A61L27/52 ,  A61L27/38 ,  A61L27/26 ,  A61L27/22 ,  A61B17/11 ,  A61B17/00

Abstract: Neurosupportive materials that possess strong tissue adhesion were synthesized by photocrosslinking two polymers, gelatin methacryloyl (GelMA) and methacryloyl-substituted tropoelastin (MeTro). The engineered materials exhibited tunable mechanical properties by varying the GelMA/MeTro ratio. In addition, GelMA/MeTro hydrogels exhibited 15-fold higher adhesive strength to nerve tissue ex vivo compared to traditionally used fibrin-based materials. Furthermore, the composites were shown to support Schwann cell (SC) viability and proliferation, as well as neurite extension and glial cell participation in vitro, which are essential cellular components for nerve regeneration. Finally, subcutaneously implanted GelMA/MeTro hydrogels exhibited slower degradation in vivo compared with pure GelMA, indicating its potential to support the growth of slowly regenerating nerves. Thus, GelMA/MeTro composites may be used as clinically relevant biomaterials to regenerate nerves and reduce the need for microsurgical suturing during nerve reconstruction.

公开(公告)号：US20220244265A1

公开(公告)日：2022-08-04

申请号：US17612713

申请日：2020-05-22

Applicant: Northeastern University

Inventor： Pushkar Kulkarni ,  Roger W. Giese ,  Poguang Wang

IPC: G01N33/58

Abstract: The disclosure relates to a diazirine precursor mass tag compound represented by structural formula (I) Also disclosed is a method for detecting analytes in a sample, comprising derivatizing the analytes with the compound of formula (I), and detecting the resulting derivatized analytes by a mass or ion mobility spectrometry.

公开(公告)号：US20220228960A1

公开(公告)日：2022-07-21

申请号：US17581076

申请日：2022-01-21

Applicant: Northeastern University

Inventor： Mohammadamin Mahmoudabadbozchelou ,  Safa Jamali

IPC: G01N9/00 ,  G06N3/04

Abstract: A comprehensive machine-learning algorithm, namely a Multi-Fidelity Neural Network (MFNN) architecture, is disclosed for data-driven constitutive meta-modelling of complex fluids. The physics-based neural networks are informed by underlying rheological constitutive models through synthetic generation of low-fidelity model-based data points.

公开(公告)号：US20220212192A1

公开(公告)日：2022-07-07

申请号：US17613138

申请日：2020-06-01

Applicant: Northeastern University

Inventor： Tania KONRY ,  Giovanni UGOLINI

IPC: B01L3/00

Abstract: Microfluidic devices and methods are provided for high-throughput generation, culturing, and analysis of cell spheroids, with subsequent isolation of selected cell spheroids for further analysis or isolation and expansion of cells from the spheroids. Any desired types of cells and matrices can be combined to form the cell spheroids and used to screen drugs and immunotherapy agents or methods, including in a personalized medicine format. Cell spheroids also can be cultivated and analyzed under hypoxic conditions. A particular advantage of the technology is the ability to isolate, enrich, and/or expand cells identified as having, or induced to have, desirable properties, such as immune cells that can be produced ex vivo and returned to the patient to combat a tumor or pathogen in vivo.

公开(公告)号：US20220193407A1

公开(公告)日：2022-06-23

申请号：US17551696

申请日：2021-12-15

Applicant: SAMSUNG ELECTRONICS CO., LTD. ,  NORTHEASTERN UNIVERSITY

Inventor： Junyeub SUH ,  Sangjoon KIM ,  Hui FANG ,  Jaehyeon RYU

IPC: A61N1/36 ,  A61N1/05

Abstract: An implant system includes an electrode portion comprising plural electrodes to perform nerve stimulation and nerve sensing, an impedance controller configured to selectively connect the plural electrodes between a stimulator to perform nerve stimulation and a sensor to perform nerve sensing based on a control signal, and set an impedance of each of the plural electrodes, and a processor configured to control a contact impedance by the plural electrodes by generating the control signal to control at least one of plural switches connected respectively to the plural electrodes, or variable resistors connected respectively to the plural electrodes, based on at least one of a selectively set purpose of the plural electrodes or a position of an electrode to which nerve stimulation is to be provided.