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公开(公告)号:US20090269245A1
公开(公告)日:2009-10-29
申请号:US12496212
申请日:2009-07-01
Applicant: Hiroshi KAWAZOE , Akishi NAKASO , Shigeharu ARIKE
Inventor: Hiroshi KAWAZOE , Akishi NAKASO , Shigeharu ARIKE
CPC classification number: B01L3/502707 , B01J19/0093 , B01J2219/00783 , B01J2219/00788 , B01J2219/00822 , B01J2219/00833 , B01J2219/0086 , B01J2219/00869 , B01L2200/12 , B01L2300/0816 , B01L2300/0838 , B01L2300/0874 , B01L2300/0887 , B01L2400/0481 , B01L2400/0655 , B81B2201/051 , B81C1/00119 , B81C2201/019 , B81C2203/032 , Y10T156/10
Abstract: A support unit for a microfluidic system includes a first support; a first adhesive layer provided on a surface of the first support; and a hollow filament laid on a surface of the first adhesive layer to have an arbitrary shape and functioning as a flow channel layer of the microfluidic system.
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公开(公告)号:US20090064790A1
公开(公告)日:2009-03-12
申请号:US12087394
申请日:2006-12-22
Applicant: Jerome Vivien Davidovits , James Scott Sutherland
Inventor: Jerome Vivien Davidovits , James Scott Sutherland
CPC classification number: B01J19/0093 , B01J2219/00783 , B01J2219/00824 , B01J2219/00831 , B01J2219/00853 , B01J2219/0086 , B01J2219/00907 , B01J2219/00963 , B01J2219/0097 , B81B7/02 , B81B2201/0264 , B81B2201/051 , B81B2203/0127 , B81C2201/019 , C03C17/04 , C03C2218/328 , C03C2218/33
Abstract: Microfluidic devices having wall structures comprised of sintered glass frit and further including a glass, glass-ceramic or ceramic membrane structure sealed by a sintered seal to said wall structures, such that a fluid passage or chamber is defined at least in part by the wall structures and said membrane structure. This allows for changes in pressure within the fluid passage or chamber to cause deflections of the membrane structure, providing for direct measurement of pressure within the device. The microfluidic device may have both floors and walls of sintered frit, or may have only walls of sintered frit, with planar floor-like substrate structures, thicker than the membrane structure defining the vertical boundaries of the internal passages. The device may include multiple fluid passages or chambers each defined at least in part by a membrane structure. Multiple membrane structures may be used in a single device, and one single membrane structure may be used for multiple passages or chamber.
Abstract translation: 具有由烧结玻璃料组成的壁结构并且还包括通过烧结密封件密封到所述壁结构的玻璃,玻璃陶瓷或陶瓷膜结构的微流体装置,使得流体通道或室至少部分地由壁结构限定 和膜结构。 这允许流体通道或腔室内的压力变化导致膜结构的偏转,从而直接测量装置内的压力。 微流体装置可以具有烧结玻璃料的两个底板和壁,或者可以仅具有烧结玻璃料的壁,其具有平面地板状衬底结构,比限定内部通道的垂直边界的膜结构更厚。 该装置可以包括多个流体通道或室,每个液体通道至少部分地由膜结构限定。 多个膜结构可以用于单个装置中,并且一个单一的膜结构可用于多个通道或室。
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公开(公告)号:US07479186B2
公开(公告)日:2009-01-20
申请号:US11415672
申请日:2006-05-01
Applicant: Stephen R. Quake , Carl L. Hansen , James M. Berger
Inventor: Stephen R. Quake , Carl L. Hansen , James M. Berger
IPC: C30B29/54
CPC classification number: C30B29/00 , B01D9/00 , B01D9/0072 , B01D9/0077 , B01J19/0046 , B01J2219/00274 , B01J2219/00286 , B01J2219/00317 , B01J2219/00389 , B01J2219/00418 , B01J2219/00432 , B01J2219/00585 , B01J2219/00756 , B01J2219/00891 , B01J2219/00907 , B01J2219/00952 , B01L3/06 , B01L3/5025 , B01L3/50273 , B01L3/502738 , B01L3/502753 , B01L7/54 , B01L9/527 , B01L2200/025 , B01L2200/027 , B01L2200/0605 , B01L2200/10 , B01L2300/0681 , B01L2300/0816 , B01L2300/0861 , B01L2300/123 , B01L2300/14 , B01L2300/18 , B01L2400/0481 , B01L2400/0655 , B01L2400/0688 , B81B2201/051 , B81B2201/054 , B81B2203/0127 , B81B2203/0315 , B81C1/00119 , B81C99/0065 , C30B7/14 , C30B29/54 , C30B29/58 , F04B43/043 , F16K99/0001 , F16K99/0015 , F16K99/0046 , F16K99/0051 , F16K99/0059 , F16K2099/0074 , F16K2099/0078 , F16K2099/008 , Y10T117/10 , Y10T117/1004 , Y10T117/1008 , Y10T117/1024
Abstract: High throughput screening of crystallization of a target material is accomplished by simultaneously introducing a solution of the target material into a plurality of chambers of a microfabricated fluidic device. The microfabricated fluidic device is then manipulated to vary the solution condition in the chambers, thereby simultaneously providing a large number of crystallization environments. Control over changed solution conditions may result from a variety of techniques, including but not limited to metering volumes of crystallizing agent into the chamber by volume exclusion, by entrapment of volumes of crystallizing agent determined by the dimensions of the microfabricated structure, or by cross-channel injection of sample and crystallizing agent into an array of junctions defined by intersecting orthogonal flow channels.
Abstract translation: 目标材料的结晶化的高通量筛选是通过将目标材料的溶液同时引入微细加工的流体装置的多个室来实现的。 然后对微制造的流体装置进行操作以改变室中的溶液状态,从而同时提供大量的结晶环境。 改变的溶液条件的控制可以由各种技术产生,包括但不限于通过体积排阻将结晶剂计量到室中的体积,通过捕获通过微结构结构的尺寸确定的结晶剂的体积, 将样品和结晶剂通道注入由相交的正交流动通道限定的连接阵列。
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公开(公告)号:US20070169686A1
公开(公告)日:2007-07-26
申请号:US11689302
申请日:2007-03-21
Applicant: Stephen Quake , Carl Hansen , James Berger
Inventor: Stephen Quake , Carl Hansen , James Berger
CPC classification number: C30B29/00 , B01D9/00 , B01D9/0072 , B01D9/0077 , B01J19/0046 , B01J2219/00274 , B01J2219/00286 , B01J2219/00317 , B01J2219/00389 , B01J2219/00418 , B01J2219/00432 , B01J2219/00585 , B01J2219/00756 , B01J2219/00891 , B01J2219/00907 , B01J2219/00952 , B01L3/06 , B01L3/5025 , B01L3/50273 , B01L3/502738 , B01L3/502753 , B01L7/54 , B01L9/527 , B01L2200/025 , B01L2200/027 , B01L2200/0605 , B01L2200/10 , B01L2300/0681 , B01L2300/0816 , B01L2300/0861 , B01L2300/123 , B01L2300/14 , B01L2300/18 , B01L2400/0481 , B01L2400/0655 , B01L2400/0688 , B81B2201/051 , B81B2201/054 , B81B2203/0127 , B81B2203/0315 , B81C1/00119 , B81C99/0065 , C30B7/14 , C30B29/54 , C30B29/58 , F04B43/043 , F16K99/0001 , F16K99/0015 , F16K99/0046 , F16K99/0051 , F16K99/0059 , F16K2099/0074 , F16K2099/0078 , F16K2099/008 , Y10T117/10 , Y10T117/1004 , Y10T117/1008 , Y10T117/1024
Abstract: High throughput screening of crystallization of a target material is accomplished by simultaneously introducing a solution of the target material into a plurality of chambers of a microfabricated fluidic device. The microfabricated fluidic device is then manipulated to vary the solution condition in the chambers, thereby simultaneously providing a large number of crystallization environments. Control over changed solution conditions may result from a variety of techniques, including but not limited to metering volumes of crystallizing agent into the chamber by volume exclusion, by entrapment of volumes of crystallizing agent determined by the dimensions of the microfabricated structure, or by cross-channel injection of sample and crystallizing agent into an array of junctions defined by intersecting orthogonal flow channels.
Abstract translation: 目标材料的结晶化的高通量筛选是通过将目标材料的溶液同时引入微细加工的流体装置的多个室来实现的。 然后对微制造的流体装置进行操作以改变室中的溶液状态,从而同时提供大量的结晶环境。 改变的溶液条件的控制可以由各种技术产生,包括但不限于通过体积排阻将结晶剂计量到室中的体积,通过捕获通过微结构结构的尺寸确定的结晶剂的体积, 将样品和结晶剂通道注入由相交的正交流动通道限定的连接阵列。
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公开(公告)号:US06171972B2
公开(公告)日:2001-01-09
申请号:US09191966
申请日:1998-11-13
Applicant: Mehran Mehregany , Christopher A. Bang , Kevin C. Stark
Inventor: Mehran Mehregany , Christopher A. Bang , Kevin C. Stark
IPC: H01L2100
CPC classification number: B05B1/3436 , B81B2201/051 , B81C1/00531
Abstract: A method for forming micromachined devices out of a polycrystalline silicon substrate using deep reactive ion etching to form the micromachined device. The method comprises the steps of providing a bulk material substrate of polycrystalline silicon, and etching the bulk material using deep reactive ion etching to form the micromachined device. The present invention also includes a method for forming a micromachined device comprising the steps of providing a first layer of single crystal silicon and etching a first set of elements on the first layer. The method further includes the steps of providing a second layer of single crystal silicon, etching a second set of elements on the second layer, and joining the first and second layers together such that the crystal planes of the first layer and the second layer are misaligned and such that the first set and the second set of elements are properly aligned.
Abstract translation: 使用深反应离子蚀刻从多晶硅衬底形成微加工器件以形成微机械加工器件的方法。 该方法包括以下步骤:提供多晶硅的散装材料基板,并使用深反应离子蚀刻来蚀刻散装材料以形成微机械加工装置。 本发明还包括一种用于形成微加工装置的方法,包括以下步骤:提供第一层单晶硅并蚀刻第一层上的第一组元件。 该方法还包括以下步骤:提供第二层单晶硅,蚀刻第二层上的第二组元件,以及将第一和第二层接合在一起,使得第一层和第二层的晶面失配 并且使得第一组和第二组元件被适当对准。
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公开(公告)号:US11760625B2
公开(公告)日:2023-09-19
申请号:US16613269
申请日:2018-05-23
Applicant: Heriot-Watt University
Inventor: Maiwenn Kersaudy-Kerhoas , Antonio Liga
CPC classification number: B81B5/00 , F16K99/0001 , G01N35/1072 , G05D7/0694 , B81B2201/051 , B81B2207/99
Abstract: A microfluidic device (100) for mixing a liquid L is provided. The microfluidic device (100) comprises a microfluidic chamber (20), having an inlet (30), and arranged to receive the liquid L therein. In use, the microfluidic device (100) is arranged to control translation through the liquid L of a body B introduced therein, wherein the translation of the body B is due to a potential field acting on the body. In this way, the controlled translation of the body B mixes the liquid L in the microfluidic chamber (20).
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公开(公告)号:US11686327B2
公开(公告)日:2023-06-27
申请号:US16493344
申请日:2017-04-07
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Erik D. Torniainen , Alexander Govyadinov , Pavel Kornilovich , David P. Markel
CPC classification number: F04F7/00 , B01L3/50273 , B01L3/502738 , B81B1/006 , F04B53/10 , B01L2200/141 , B01L2200/16 , B01L2400/0605 , B81B2201/051 , B81B2203/0338
Abstract: The present disclosure is drawn to inertial pumps. An inertial pump can include a microfluidic channel, a fluid actuator located in the microfluidic channel, and a check valve located in the microfluidic channel. The check valve can include a moveable valve element, a narrowed channel segment located upstream of the moveable valve element, and a blocking element formed in the microfluidic channel downstream of the moveable valve element. The narrowed channel segment can have a width less than a width of the moveable valve element so that the moveable valve element can block fluid flow through the check valve when the moveable valve element is positioned in the narrowed channel segment. The blocking element can be configured such that the blocking element constrains the moveable valve element within the check valve while also allowing fluid flow when the moveable valve element is positioned against the blocking element.
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公开(公告)号:US11673797B2
公开(公告)日:2023-06-13
申请号:US17192126
申请日:2021-03-04
Inventor: Shinan Wang
CPC classification number: B81C1/00047 , B81B1/002 , G01L9/0042 , B81B2201/0264 , B81B2201/051 , B81B2203/0315 , B81C2201/0143 , B81C2201/0146 , B81C2201/0181
Abstract: A microstructure and a method for manufacturing the same includes: disposing a liquid film on a surface of a substrate, wherein a solid-liquid interface is formed where the liquid film is in contact with the substrate; and irradiating the substrate with a laser of a predetermined waveband to etch the substrate at the solid-liquid interface, wherein the position where the laser is irradiated on the solid-liquid interface moves at least along a direction parallel to the surface of the substrate, and the absorption rate of the liquid film for the laser is greater than the absorption rate of the substrate for the laser.
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公开(公告)号:US20180237325A1
公开(公告)日:2018-08-23
申请号:US15751693
申请日:2016-08-12
Applicant: Corning Incorporated
IPC: C03B19/14 , C03B23/203 , C03C23/00 , C03B17/02 , B32B17/06
CPC classification number: C03B19/1453 , B32B17/06 , B33Y10/00 , B33Y70/00 , B81B2201/051 , B81C99/0025 , C03B17/02 , C03B19/1492 , C03B23/203 , C03B23/245 , C03C23/0025
Abstract: An additive manufacturing process includes forming an object material stack using sheet materials without use of binder material between the sheet materials and forming features of the cross-sectional layers of a 3D object in the corresponding sheet materials. Another process involves forming features of the cross-sectional layers of a 3D object in soot layers of a laminated soot sheet. A manufactured article includes three or more glass layers laminated together without any binder material between the glass layers. At least one of the glass layers is composed of silica or doped silica, and at least one feature is formed in at least one of the glass layers.
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公开(公告)号:US09891189B2
公开(公告)日:2018-02-13
申请号:US15477982
申请日:2017-04-03
Applicant: International Business Machines Corporation
Inventor: Sebastian U. Engelmann , Stephen M. Rossnagel , Ying Zhang
IPC: G01N27/403 , G01N27/414 , B82B1/00 , B82B3/00 , G01N33/487
CPC classification number: G01N27/4146 , B01L3/502707 , B01L3/502761 , B01L2200/0663 , B01L2300/0861 , B01L2300/0887 , B01L2300/0896 , B81B2201/051 , B81C1/00119 , B81C2201/0181 , B82B1/005 , B82B3/008 , G01N27/4145 , G01N33/48721
Abstract: Techniques for fabricating horizontally aligned nanochannels are provided. In one aspect, a method of forming a device having nanochannels is provided. The method includes: providing a SOI wafer having a SOI layer on a buried insulator; forming at least one nanowire and pads in the SOI layer, wherein the nanowire is attached at opposite ends thereof to the pads, and wherein the nanowire is suspended over the buried insulator; forming a mask over the pads, the mask having a gap therein where the nanowire is exposed between the pads; forming an alternating series of metal layers and insulator layers alongside one another within the gap and surrounding the nanowire; and removing the nanowire to form at least one of the nanochannels in the alternating series of the metal layers and insulator layers. A device having nanochannels is also provided.
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