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公开(公告)号:US09658156B2
公开(公告)日:2017-05-23
申请号:US13578593
申请日:2011-02-25
Applicant: Michael I. Larkin
Inventor: Amy D. Hanlon , Michael I. Larkin
CPC classification number: G01N21/49 , G01N15/0211 , G01N15/1429 , G01N15/1434 , G01N21/4738 , G01N2015/0038 , G01N2015/0092 , G01N2015/0216 , G01N2015/0222 , G01N2201/06113 , G01N2201/12
Abstract: This invention enables high throughput detection of small molecule effectors of particle association, as well as quantification of association constants, stoichiometry, and conformation. Given a set of particle solutions having different concentrations, dynamic light scattering measurements are used to determine the average hydrodynamic radius, as a function of concentration. The series of average hydrodynamic radii as a function of concentration are fitted with stoichiometric association models containing the parameters of molar mass, modeled concentrations, and modeled hydrodynamic radii of the associated complexes. In addition to the average hydrodynamic radii value analysis, the experimental data may be fit/analyzed in alternate ways. This method may be applied to a single species that is self-associating or to multiple species that are hetero-associating. This method may also be used to characterize and quantify the association between a modulator and the associating species.
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公开(公告)号:US20170138860A1
公开(公告)日:2017-05-18
申请号:US15322874
申请日:2015-07-02
Applicant: NATIONAL UNIVERSITY OF SINGAPORE
Inventor: Zhiwei HUANG
CPC classification number: G01N21/65 , A61B1/018 , A61B5/0075 , A61B5/0084 , A61B2560/0223 , G01J3/0218 , G01J3/44 , G01J2003/123 , G01N21/274 , G01N2201/0612 , G01N2201/08 , G01N2201/12 , G01N2201/129
Abstract: Characterizing, identifying, or diagnosing the type and/or nature of a sample or a tissue such as an abnormal growth using a Raman spectrum includes analyzing distinct spectral subintervals within the Raman spectrum in two distinct wavelength ranges, such as FP and HW wavelength ranges, to identify a match with one or more reference markers in one or both wavelength ranges; and from the match characterizing, identifying, or diagnosing the type and/or nature of the sample or tissue. FP and HW Raman spectra can be detected or acquired simultaneously using a single diffraction grating.
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公开(公告)号:US20170136166A1
公开(公告)日:2017-05-18
申请号:US15132117
申请日:2016-04-18
Applicant: NATIONAL TSING HUA UNIVERSITY , NATIONAL TAIWAN UNIVERSITY , NATIONAL TAIWAN UNIVERSITY HOSPITAL
Inventor: Hung-Shao Chen , Jenq-Wen Huang , Hsi-Pin Ma
IPC: A61M1/28 , G01F23/296 , G01N21/25 , G06F19/00
CPC classification number: A61M1/282 , A61M1/1609 , A61M1/28 , A61M2205/331 , A61M2205/3375 , A61M2205/3553 , A61M2205/3592 , A61M2205/502 , G01F23/2962 , G01N21/251 , G01N21/255 , G01N21/51 , G01N2201/062 , G01N2201/12 , G06F19/00 , G06F19/3418
Abstract: A tele-care management system for peritoneal dialysis (PD) includes at least a container, a holder, a removable detection device and a mobile device. The container is for placing effluent fluid of peritoneal dialysis. The holder is for placing the container. The removable detection device includes a detection unit, a processor and a communication interface, wherein the processor detects the turbidity and the chrominance of the effluent fluid and performs a quantitative analysis on the effluent fluid, and generates a turbidity prediction value based on the detection result of the detection unit. The processor respectively calculates first and second turbidity values, which correspond to first and second turbidity respectively, for the effluent fluid according to first and second algorithms and selects one from the first and second turbidity values to generate the turbidity prediction value based on a predetermined threshold value sent to a mobile device for further processing.
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公开(公告)号:US09651498B2
公开(公告)日:2017-05-16
申请号:US14412479
申请日:2013-07-02
Applicant: NOVA MEASURING INSTRUMENTS LTD.
Inventor: Gilad Barak , Elad Dotan , Alon Belleli
CPC classification number: G01N21/8806 , G01N21/55 , G01N21/9501 , G01N2021/8825 , G01N2201/12 , H01L22/12
Abstract: A method and system are presented for use in inspection of via containing structures. According to this technique, measured data indicative of a spectral response of a via-containing region of a structure under measurements is processed, and, upon identifying a change in at least one parameter of the spectral response with respect to a spectral signature of the via-containing region, output data is generated indicative of a possible defect at an inner surface of the via.
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公开(公告)号:US20170130186A1
公开(公告)日:2017-05-11
申请号:US15322560
申请日:2015-07-02
Applicant: Biogen MA Inc.
Inventor: Brandon Berry , Justin Moretto
CPC classification number: C12M41/32 , C12M41/48 , G01N21/65 , G01N2201/12
Abstract: Aspect of the disclosure relate to methods of assessing a bioreactor culture that involve determining a culture parameter of the manufacturing-scale bioreactor culture using a model that relates a Raman spectrum to the culture parameter. Related bioreactor system are also provided.
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公开(公告)号:US09646223B2
公开(公告)日:2017-05-09
申请号:US14652886
申请日:2013-12-03
Applicant: NEC Corporation
Inventor: Akari Sato
CPC classification number: G06K9/60 , G01N21/251 , G01N21/27 , G01N21/4738 , G01N21/84 , G01N33/0098 , G01N2021/8466 , G01N2201/12 , G06K9/2036 , G06K9/209 , G06K9/3233 , G06K9/3241 , G06K9/4652 , G06K9/4661
Abstract: An image measuring system includes: a reflecting body arranged near a plant to be measured; a photographing unit for photographing the reflecting body and outputting the photographed image; an image analyzing unit for detecting, in the photographed image, the area of the reflecting body and acquiring the color information of the area; an absolute spectral irradiance distribution calculating unit for calculating, on the basis of the color information, the absolute spectral irradiance distribution, which is the distribution of the absolute values of the spectral irradiance in the area; a photon flux density calculating unit for calculating, on the basis of the absolute spectral irradiance distribution, the photon flux density; and a Leaf Area Index calculating unit for calculating, on the basis of the photon flux density, the Leaf Area Index.
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公开(公告)号:US09625382B2
公开(公告)日:2017-04-18
申请号:US14439259
申请日:2013-10-30
Applicant: VALMET AUTOMATION OY
Inventor: Markku Mäntylä
CPC classification number: G01N21/57 , G01N21/47 , G01N21/86 , G01N21/8901 , G01N33/346 , G01N2201/06113 , G01N2201/062 , G01N2201/069 , G01N2201/12
Abstract: An apparatus of measuring a small scale property of a sheet, the apparatus includes: a first light source for illuminating the sheet moving with respect to the illumination; a detector for forming a total intensity of reflection of the light illuminating the moving sheet by each detection; a detected dimension of the reflection on the sheet in the direction of the movement being limited the same as or shorter than a lowest acceptable spatial resolution of the measurement; a duration of each detection being equal to or shorter than the lowest acceptable spatial resolution divided by a speed of the moving sheet; and a processing unit for forming information about a small scale variation of gloss of the sheet on the basis of the detections by the detector.
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公开(公告)号:US09624769B2
公开(公告)日:2017-04-18
申请号:US14383951
申请日:2013-11-11
Applicant: Halliburton Energy Services, Inc.
Inventor: David L. Perkins , Christopher Michael Jones , Michael T. Pelletier
CPC classification number: E21B49/081 , G01N21/27 , G01N21/274 , G01N21/85 , G01N30/86 , G01N2030/025 , G01N2030/042 , G01N2030/8854 , G01N2201/12
Abstract: A disclosed measurement system includes a fluid system that circulates a sample fluid exhibiting one or more unknown characteristics and being configured to receive a standard fluid that exhibits a known characteristic corresponding to at least one of the one or more unknown characteristics, an isolation cell fluidly coupled to the fluid system such that the sample fluid and a mixture of the sample fluid and the standard fluid are able to enter the isolation cell, an analyte-sensitive measurement device having one or more sensors associated therewith and being configured to analyze the sample fluid and the mixture and generate response signals corresponding to the one or more unknown characteristics of the sample fluid, and a signal processor configured to receive and perform standard addition calculations on the response signals in order to determine a concentration of the one or more unknown characteristics.
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公开(公告)号:US20170103517A1
公开(公告)日:2017-04-13
申请号:US15389442
申请日:2016-12-22
Applicant: KLA-Tencor Corporation
Inventor: Satya Kurada , Raghav Babulnath , Kwok Ng , Lisheng Gao
IPC: G06T7/00 , G01N21/95 , G01N21/956 , G06K9/66
CPC classification number: G06T7/0006 , G01N21/9501 , G01N21/956 , G01N21/95607 , G01N2021/95676 , G01N2201/06113 , G01N2201/068 , G01N2201/10 , G01N2201/12 , G06K9/00 , G06K9/66 , G06T7/0008 , G06T7/001 , G06T2207/20081 , G06T2207/30148
Abstract: Methods and systems for design based sampling and binning for yield critical defects are provided. One method includes aligning each image patch in each inspection image frame generated for a wafer by an optical subsystem of an inspection system to design information for the wafer. The method also includes deriving multiple layer design attributes at locations of defects detected in the image patches. In addition, the method includes building a decision tree with the multiple layer design attributes. The decision tree is used to separate the defects into bins with different yield impacts on a device being formed on the wafer. The method also includes binning the defects with the decision tree.
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公开(公告)号:US20170102318A1
公开(公告)日:2017-04-13
申请号:US14879920
申请日:2015-10-09
Applicant: Honeywell International Inc.
Inventor: Wei Yang , Teresa M. Marta , Martin Willett , Rodney R. Watts
CPC classification number: G01N21/1702 , G01J5/02 , G01J5/42 , G01N21/61 , G01N33/0027 , G01N2021/1704 , G01N2201/067 , G01N2201/068 , G01N2201/12
Abstract: Gas detector devices, systems, and methods using a Golay cell are described herein. One device includes a microphone having a front surface with an sound collecting aperture for receiving sound, a substrate, a gas cavity formed in the substrate such that the gas cavity is in gas communication with the sound collecting aperture and the front surface forms a side surface of the gas cavity, and a window abutting the substrate to form a side surface of the gas cavity.
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