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公开(公告)号：US12281346B2
公开(公告)日：2025-04-22
申请号：US17306251
申请日：2021-05-03
Inventor： Violeta Sanchez Nogue , Eric M. Karp , Patrick Owen Saboe , Lucas Hans Loetscher , Sybil Sharvelle
Abstract: The present disclosure relates to a method that includes utilizing a microorganism for the converting of a substrate to an acid contained in a mixture that includes the acid and water, maintaining a pH of the mixture to less than 5, and treating the mixture with a first stream comprising an organic.
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公开(公告)号：US12253662B2
公开(公告)日：2025-03-18
申请号：US17648923
申请日：2022-01-25
Inventor： Randy A. Bartels , Jeffrey J. Field
Abstract: In an embodiment, a method includes obtaining radiation emitted from a radiation source. The method includes modulating the radiation with a time-varying modulation to generate a time-varying illumination pattern with a known modulation. The illumination pattern includes a time-varying intensity for each of a plurality of spatial locations. The method includes illuminating a target volume with the illumination pattern. The method includes collecting a signal generated by one or more objects within the target volume in response to illumination by the illumination pattern. The method includes estimating a location of each of the one or more objects based on the collected signal and the known modulation.
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公开(公告)号：US20250066807A1
公开(公告)日：2025-02-27
申请号：US18718250
申请日：2022-12-14
Applicant: COLORADO STATE UNIVERSITY RESEARCH FOUNDATION , MONSANTO TECHNOLOGY LLC , THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
Inventor： Todd GAINES , Carlos RIGON , Franck DAYAN , Anita Küpper , Roland BEFFA , Darci GIACOMINI , Patrick TRANEL
IPC: C12N15/82 , C12Q1/6895
Abstract: The present disclosure relates to a plant or plant part comprising increased expression of a polynucleotide encoding a CYP72A219 polypeptide that confers to the plant or plant part tolerance to HPPD inhibitor herbicides, such as tembotrione or mesotrione. The disclosure further provides kits for identifying herbicide resistant plants and methods for determining whether a plant is herbicide resistant.
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公开(公告)号：US20250031650A1
公开(公告)日：2025-01-30
申请号：US18707052
申请日：2022-11-04
Inventor： Stephen Pearce , Caitlynd Krosch , Andrew Katz , Rocio Alarcon Reverte , Karl Ravet , Forrest Wold-McGimsey
IPC: A01H6/46 , C12N5/04 , C12N9/00 , C12N15/82 , C12Q1/6895
Abstract: The disclosure relates to compositions and methods for reducing free asparagine concentration in the grain of wheat plants. The compositions comprise wheat plants, plant parts, plant cells, and seeds comprising a loss-of-function mutation in at least one endogenous ASPARAGINE SYNTHETASE 2 (ASN2) gene. The grain of wheat plants has reduced acrylamide-forming potential. Low acrylamide products produced from the grain are also provided.
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公开(公告)号：US12201029B2
公开(公告)日：2025-01-14
申请号：US17579048
申请日：2022-01-19
Inventor： Kristen Buchanan , Xiao Wang , Xuemei Cheng
Abstract: A topological spin memory effect, defined as the recovery of magnetic skyrmions or magnetic bubble skyrmions in magnetic thin films after a transition to a dramatically different spin texture, is used for encrypted non-volatile information storage. The storage strategy is based on magnetic skyrmions, that is, topologically protected spin textures comprising chiral domain walls surrounding small (e.g., nanometers to microns in diameter), typically circular, single-domain cores. Systems and methods are described for encrypted non-volatile information storage based on a spin memory effect in magnetic thin films that support skyrmions. Systems and methods encrypt and recover information stored in the form of magnetic skyrmions.
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Patent Agency Ranking
公开(公告)号：US12180507B2
公开(公告)日：2024-12-31
申请号：US15749733
申请日：2016-08-05
Inventor： Salman R. Khetani , Mitchell J. Durham , Brenton R. Ware
IPC: C12N5/00 , A61K35/407 , A61K35/44 , C12N5/071 , G01N33/50
Abstract: The disclosure relates to in vitro cultures of human hepatocytes, and in particular co-cultures systems including human hepatocytes, non-parenchymal cells, and human endothelial cells, and the use of the co-cultures in developing and screening drugs.
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公开(公告)号：US12171670B2
公开(公告)日：2024-12-24
申请号：US18030462
申请日：2021-10-05
Inventor： Christian M. Puttlitz , Mitchell Page
Abstract: A biocompatible implant, as well as method of fabricating the implant and repairing an annular defect in annulus fibrosus (AF) of an intervertebral disc (IVD) disposed in a functional spinal unit (FSU), includes an insert that provides faces that can interface with the defect to repair or treat the AF. The implant can deliver biological and mechanical factors to enhance healing in an annular defect and prevent recurrence of herniation symptoms. The implant can be fabricated using a hybrid of first fibrous scaffold structure including at least a first layer and a second layer of first fibers fabricated via three-dimensional fiber deposition (3FD) and second fibrous scaffold structure including a third layer and a fourth layer of second fibers formed via melt electrowriting (MEW). Suitable attachment methods, including bio-adhesives can be used to bond the implant to the IVD and/or FSU.
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公开(公告)号：US20240392701A1
公开(公告)日：2024-11-28
申请号：US18691113
申请日：2022-09-22
Inventor： Todd Bandhauer , Nickolas Roberts
Abstract: An ultra-efficient turbo-compression cooling system links an organic Rankine power cycle and a vapor compression cooling cycle using a turbine and compressor that shares a single shaft and further linked to an evaporative condenser. The power cycle implements a waste heat exchanger configured to evaporate a working fluid and a turbine configured to receive the evaporated working fluid. The turbine has a plurality of vanes disposed around a central shaft and configured to rotate as the working fluid expands to a lower pressure within the turbine. An evaporative condenser then condenses the working fluid to a saturated liquid and a mechanical pump pumps the saturated liquid to reenter the waste heat waste heat exchanger. The cooling cycle implements a compressor configured to increase the pressure of the working fluid, with the evaporative condenser (shared with the power cycle) configured to condense the working fluid to a saturated liquid upon exiting the compressor, an expansion valve wherein the working fluid expands to a lower pressure, and an evaporator rejecting heat from a circulating fluid to the working fluid, thereby cooling the circulating fluid.
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公开(公告)号：US12130265B2
公开(公告)日：2024-10-29
申请号：US17706989
申请日：2022-03-29
Inventor： Steve Simske , Katrina Weinmann
CPC classification number: G01N3/42 , B25J15/0019
Abstract: A method for indentation of physical items may include forming, via an indenter, a plurality of first indents in a first surface of a first physical item, and validating a first material of the first physical item based at least in part on the first indents. The first indents may be disposed within a first defined region of the first surface and arranged in a first encoded pattern corresponding to a first item-specific serialization code for the first physical item.
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公开(公告)号：US20240327855A1
公开(公告)日：2024-10-03
申请号：US18621953
申请日：2024-03-29
Inventor： Stephen Pearce , Caitlynd Krosch , Karl Ravet , Rocio Alarcon Reverte , Andrew Katz , Forrest Wold-McGimsey
CPC classification number: C12N15/8243 , C12N9/22 , C12N15/11 , C12N15/8213 , C12N2310/20
Abstract: The disclosure relates to compositions and methods for reducing polyphenol oxidase (PPO) activity in plants, including wheat plants. The compositions comprise plants, plant parts, plant cells, and seeds comprising a mutation in at least one endogenous PPO1 or PPO2 gene. Products produced from the grain of plants have reduced browning.
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