公开(公告)号：US3884904A

公开(公告)日：1975-05-20

申请号：US37238673

申请日：1973-06-21

Applicant: ABBOTT LAB

Inventor： JONES PETER HADLEY ,  MCALPINE JAMES BRUCE ,  PAUVLIK JEANNE MARIE ,  PERUN THOMAS JOHN

IPC: C07H17/08 ,  C07C129/18

CPC classification number: C07H17/08

Abstract: Covers 11-substituted erythromycin B derivatives having a formula selected from the group consisting of:

WHERE R is selected from the group consisting of lower alkyl and -CHR3SR4 where R3 and R4 are loweralkyl, and R1 and R2 are hydrogen or loweralkyl and;

WHERE R1, R2 and R3 are as before defined. Said erythromycin derivatives are useful as antibiotics or as intermediates useful in preparing other useful antibiotic compounds.

Abstract translation: 覆盖具有选自以下的式的11-取代的红霉素B衍生物：

公开(公告)号：US3884903A

公开(公告)日：1975-05-20

申请号：US50441774

申请日：1974-09-09

Applicant: ABBOTT LAB

Inventor： JONES PETER HADLEY ,  MARTIN JERRY ROY ,  MCALPINE JAMES BRUCE ,  PAUVLIK JEANNE MARIE ,  TADANIER JOHN SOLOMAN

IPC: C07H17/08 ,  C07C129/18

CPC classification number: C07H17/08

Abstract: Covers a 4''''-deoxy-4''''-oxoerythromycin compounds and derivatives thereof which are useful as antibiotics having a formula selected from the group consisting of:

WHERE R is -CH2SR3, R2 is hydrogen or loweralkyl, R3 is loweralkyl, and R1 is hydrogen or loweralkanoyl;

WHERE R1 and R2 are as before defined;

WHERE R is hydrogen or CH3CO;

where R1 is hydrogen or RCO, R is loweralkyl, R2 is hydrogen, CH3CO or RCO where R is loweralkyl; and

WHERE R3 is hydrogen or RCO where R is loweralkyl.

Abstract translation: 包含4' - 脱氧-4'-氧代红霉素化合物及其衍生物，其可用作具有选自以下的式的抗生素：