公开(公告)号：US3684794A

公开(公告)日：1972-08-15

申请号：US3684794D

申请日：1970-12-18

Applicant: ABBOTT LAB

Inventor： MARTIN JERRY ROY

IPC: C07H17/08 ,  C07C47/18

CPC classification number: C07H17/08 ,  Y10S435/886 ,  Y10S514/916

Abstract: 3-O-( Alpha -L-mycarosyl)-8-hydroxyerythronolide B is useful as an antipyretic agent. The compound is prepared by the fermentation of 8-hydroxyerythronolide B with Streptomyces erythreus NRRL 3887 in a suitable nutrient media.

Abstract translation: 3-O-（α-L-霉糖酰基）-8-羟基红参酮内酯B可用作解热剂。 该化合物通过在合适的营养培养基中发酵8-羟基红霉内酯B与赤藓链霉菌NRRL 3887来制备。

公开(公告)号：US3884903A

公开(公告)日：1975-05-20

申请号：US50441774

申请日：1974-09-09

Applicant: ABBOTT LAB

Inventor： JONES PETER HADLEY ,  MARTIN JERRY ROY ,  MCALPINE JAMES BRUCE ,  PAUVLIK JEANNE MARIE ,  TADANIER JOHN SOLOMAN

IPC: C07H17/08 ,  C07C129/18

CPC classification number: C07H17/08

Abstract: Covers a 4''''-deoxy-4''''-oxoerythromycin compounds and derivatives thereof which are useful as antibiotics having a formula selected from the group consisting of:

WHERE R is -CH2SR3, R2 is hydrogen or loweralkyl, R3 is loweralkyl, and R1 is hydrogen or loweralkanoyl;

WHERE R1 and R2 are as before defined;

WHERE R is hydrogen or CH3CO;

where R1 is hydrogen or RCO, R is loweralkyl, R2 is hydrogen, CH3CO or RCO where R is loweralkyl; and

WHERE R3 is hydrogen or RCO where R is loweralkyl.

Abstract translation: 包含4' - 脱氧-4'-氧代红霉素化合物及其衍生物，其可用作具有选自以下的式的抗生素：

公开(公告)号：US3884902A

公开(公告)日：1975-05-20

申请号：US35712473

申请日：1973-05-04

Applicant: ABBOTT LAB

Inventor： HALLAS ROBERT ,  MARTIN JERRY ROY ,  SOLOMAN JOHN

IPC: C07H17/08 ,  C07C129/18

CPC classification number: C07H17/08

Abstract: Covers erythromycin sulfonyl derivatives which are useful as antibiotics when administered to warm blooded animals.

Abstract translation: 涵盖红霉素磺酰基衍生物，当向温血动物施用时可用作抗生素。