公开(公告)号：US20230295697A1

公开(公告)日：2023-09-21

申请号：US17940650

申请日：2022-09-08

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Long CAI ,  Eric LUBECK ,  Timur ZHIYENTAYEV ,  Ahmet COSKUN ,  Ting-Fang HE ,  Chang Ho SOHN ,  Sheel SHAH

IPC: C12Q1/6841 ,  C12N15/10 ,  G01N21/64 ,  G02B21/06 ,  G02B21/16

CPC classification number: C12Q1/6841 ,  C12N15/1065 ,  G01N21/6428 ,  G01N21/6458 ,  G02B21/06 ,  G02B21/16 ,  G01N2201/068 ,  G01N2201/10

Abstract: The present invention, among other things, provides technologies for detecting and/or quantifying nucleic acids in cells, tissues, organs or organisms. In some embodiments, through sequential barcoding, the present invention provides methods for high-throughput profiling of a large number of targets, such as transcripts and/or DNA loci.

公开(公告)号：US20250043340A1

公开(公告)日：2025-02-06

申请号：US18906096

申请日：2024-10-03

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Long CAI ,  Eric LUBECK ,  Timur ZHIYENTAYEV ,  Ahmet COSKUN ,  Ting-Fang HE ,  Chang Ho SOHN ,  Sheel SHAH

IPC: C12Q1/6841 ,  C12N15/10 ,  G01N21/64 ,  G02B21/06 ,  G02B21/16

Abstract: The present invention, among other things, provides technologies for detecting and/or quantifying nucleic acids in cells, tissues, organs or organisms. In some embodiments, through sequential barcoding, the present invention provides methods for high-throughput profiling of a large number of targets, such as transcripts and/or DNA loci.

公开(公告)号：US20210180127A1

公开(公告)日：2021-06-17

申请号：US17103757

申请日：2020-11-24

Applicant: California Institute of Technology

Inventor： Long CAI ,  Chang Ho SOHN ,  Yandong ZHANG

IPC: C12Q1/6874 ,  C12Q1/6818 ,  C12Q1/6806 ,  C12Q1/6825

Abstract: The present application describes compositions and methods for identifying and quantitating molecular targets within a cellular environment. Specifically, provided herein are compositions and methods for separately identifying and quantifying each of one or more molecular targets from a single cell. More specifically, provided herein are compositions and methods for separately identifying and quantifying the same molecular target from a single cell.

公开(公告)号：US20230212658A1

公开(公告)日：2023-07-06

申请号：US17940356

申请日：2022-09-08

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Long CAI ,  Eric LUBECK ,  Timur ZHIYENTAYEV ,  Ahmet COSKUN ,  Ting-Fang HE ,  Chang Ho SOHN ,  Sheel SHAH

IPC: C12Q1/6841 ,  G01N21/64 ,  G02B21/16 ,  G02B21/06 ,  C12N15/10

CPC classification number: C12Q1/6841 ,  G01N21/6428 ,  G02B21/16 ,  G01N21/6458 ,  G02B21/06 ,  C12N15/1065 ,  G01N2201/068 ,  G01N2201/10

Abstract: The present invention, among other things, provides technologies for detecting and/or quantifying nucleic acids in cells, tissues, organs or organisms. In some embodiments, through sequential barcoding, the present invention provides methods for high-throughput profiling of a large number of targets, such as transcripts and/or DNA loci.

公开(公告)号：US20200080139A1

公开(公告)日：2020-03-12

申请号：US16572511

申请日：2019-09-16

Applicant: California Institute of Technology

Inventor： Long CAI ,  Eric LUBECK ,  Timur ZHIYENTAYEV ,  Ahmet COSKUN ,  Ting-Fang HE ,  Chang Ho SOHN ,  Sheel SHAH

IPC: C12Q1/6841 ,  C12N15/10 ,  G01N21/64 ,  G02B21/06 ,  G02B21/16

Abstract: The present invention, among other things, provides technologies for detecting and/or quantifying nucleic acids in cells, tissues, organs or organisms. In some embodiments, through sequential barcoding, the present invention provides methods for high-throughput profiling of a large number of targets, such as transcripts and/or DNA loci.