公开(公告)号：US12002672B2

公开(公告)日：2024-06-04

申请号：US16630007

申请日：2018-06-29

Applicant: DH Technologies Development Pte. Ltd.

Inventor： Bruce Collings ,  Pascal Martin

IPC: H01J49/00 ,  H01J49/06 ,  H01J49/42

CPC classification number: H01J49/067 ,  H01J49/0031 ,  H01J49/4225 ,  H01J49/426

Abstract: Apparatus and methods for controlling contamination of components contained within the high-vacuum chambers of mass spectrometer systems are provided. The apparatus and methods employ a beam of neutral gas injected in a contra-flow configuration to incoming particle stream from the ionization chamber. The contra-flow can be in the directly opposite counter-flow direction (e.g., 180 degrees) or at a cross-flow angle to the incoming ion stream (e.g., flowing at an angle between about 10 degrees and 170 degrees). The contra-flow disrupts the axial gas flow and diverts neutral molecules and other undesirable contaminants before they reach the high vacuum stages (e.g., beyond the IQ0 orifice) of the spectrometer. By reducing the transmission of contaminants into the sensitive components housed deep within the mass spectrometer, the present invention can increase throughput, improve robustness, and/or decrease the downtime typically required to vent/disassemble/clean the fouled components.

公开(公告)号：US20210090870A1

公开(公告)日：2021-03-25

申请号：US16630007

申请日：2018-06-29

Applicant: DH Technologies Development Pte. Ltd.

Inventor： Bruce Collings ,  Pascal Martin

IPC: H01J49/06 ,  H01J49/00 ,  H01J49/42

Abstract: Apparatus and methods for controlling contamination of components contained within the high-vacuum chambers of mass spectrometer systems are provided. The apparatus and methods employ a beam of neutral gas injected in a contra-flow configuration to incoming particle stream from the ionization chamber. The contra-flow can be in the directly opposite counter-flow direction (e.g., 180 degrees) or at a cross-flow angle to the incoming ion stream (e.g., flowing at an angle between about 10 degrees and 170 degrees). The contra-flow disrupts the axial gas flow and diverts neutral molecules and other undesirable contaminants before they reach the high vacuum stages (e.g., beyond the IQ0 orifice) of the spectrometer. By reducing the transmission of contaminants into the sensitive components housed deep within the mass spectrometer, the present invention can increase throughput, improve robustness, and/or decrease the downtime typically required to vent/disassemble/clean the fouled components.

公开(公告)号：US12027357B2

公开(公告)日：2024-07-02

申请号：US17622568

申请日：2020-07-22

Applicant: DH Technologies Development PTE. LTD.

Inventor： Bruce Collings ,  Pascal Martin

IPC: H01J49/00 ,  H01J49/02 ,  H01J49/06

CPC classification number: H01J49/0031 ,  H01J49/0036 ,  H01J49/022 ,  H01J49/067

Abstract: In one aspect, a method of modulating transmission of ions in a mass spectrometer is disclosed, which comprises generating an ion beam comprising a plurality of ions, directing the ion beam to an ion optic positioned in the path of the ion beam, wherein the ion optic includes at least one opening through which the ions can pass, and applying one or more voltage pulses at a selected duty cycle to said ion optic so as to obtain a desired attenuation of brightness of the ion beam passing through the ion optic, where a pulse width of said voltage pulses at said selected duty cycle is determined by identifying a pulse width on a calibration normalized ion intensity versus pulse width relation for said ions that corresponds to said desired attenuation on an ideal normalized ion intensity versus pulse width relation for said ions.

公开(公告)号：US11798797B2

公开(公告)日：2023-10-24

申请号：US17312907

申请日：2019-12-12

Applicant: DH TECHNOLOGIES DEVELOPMENT PTE. LTD.

Inventor： Bruce Collings

IPC: H01J49/42 ,  H01J49/06

CPC classification number: H01J49/426 ,  H01J49/063

Abstract: Methods and apparatus are disclosed for reducing ion reflections between multipole segments in a mass spectrometer by matching the effective potential between the two segments. Mass spectrometers having at least two multipole segments separated from each other along a longitudinal axis of the mass spectrometer such that a boundary region exists through which ions are drawn from an upstream segment to a downstream segment, and wherein each multipole segment further includes a set of spaced-apart rod-shaped electrodes disposed around the longitudinal axis and having a field radius defined by an inscribed circle between the innermost portions of each electrode. Effective potential matching can be achieved by either supplying RF signals of different amplitudes to each segment and/or by modifying the field strength of the segments. In one embodiment, the multipole segments are configured such that the upstream multipole segment has a smaller field radius than the downstream segment.