公开(公告)号：US20240355611A1

公开(公告)日：2024-10-24

申请号：US18685534

申请日：2022-08-23

Applicant: DH Technologies Development Pte. Ltd.

Inventor： David M. COX ,  Mircea GUNA ,  Yang KANG ,  Mircea MANOLESCU ,  Andrei SONOC

IPC: H01J49/42

CPC classification number: H01J49/421

Abstract: An ion mass filter for use in a mass spectrometer is disclosed, which includes a plurality of rods arranged in a multipole configuration to provide a passageway through which ions can travel, said plurality of rods being configured for application of RF voltages thereto to generate an electromagnetic field within the passageway for providing radial confinement of the ions and further configured for application of a DC voltage thereto, and at least two pairs of auxiliary electrodes interspersed between the plurality of multipole rods, where one pair forms a first pole of the auxiliary electrodes and the other pair forms a second pole of the auxiliary electrodes. A controller can provide one or more control signals to the DC voltage source so as to switch the polarity of the DC voltage differential between the two poles according to a predefined criterion.

公开(公告)号：US20250069873A1

公开(公告)日：2025-02-27

申请号：US18725973

申请日：2022-12-22

Applicant: DH Technologies Development Pte. Ltd.

Inventor： Gordana IVOSEV ,  Chang LIU ,  David M. COX

IPC: H01J49/00

Abstract: A method and system for detecting a signal measurement error, the method including providing a well plate including error correction wells and sample wells, each sample well including a single sample, and each error correction well including a mixture of samples from two or more sample wells. The method includes receiving an aliquot from the wells at a sample receiver, measuring a signal for the received aliquot, calculating an expected signal for each of the error correction wells, comparing the measured signal to the calculated expected signal for each error correction well, and determining whether an error exists in the signal of at least one sample well. When the error exists, the method correlates the error to one or more sample wells.

公开(公告)号：US20240355612A1

公开(公告)日：2024-10-24

申请号：US18685356

申请日：2022-08-23

Applicant: DH Technologies Development Pte. Ltd.

Inventor： David M. COX ,  Manuel FAUR ,  Mircea GUNA ,  Yang KANG ,  Andrei SONOC

IPC: H01J49/42 ,  H01J49/00

CPC classification number: H01J49/4215 ,  H01J49/004

Abstract: In one aspect, an ion filter for use in a mass spectrometer is disclosed, which includes a plurality of rods arranged in a multipole configuration to provide a passageway through which ions can travel, said plurality of rods being configured for application of RF voltages thereto to provide an electromagnetic field within the passageway for providing radial confinement of the ions and further configured for application of a DC voltage thereto. At least two pairs of auxiliary electrodes are interspersed between the plurality of rods and are configured for application of a DC bias voltage with one polarity to one of said pairs and a DC bias voltage with an opposite polarity to the other one of said pairs to provide a DC potential difference between the auxiliary electrodes and the plurality of rods.