公开(公告)号：US20240355611A1

公开(公告)日：2024-10-24

申请号：US18685534

申请日：2022-08-23

Applicant: DH Technologies Development Pte. Ltd.

Inventor： David M. COX ,  Mircea GUNA ,  Yang KANG ,  Mircea MANOLESCU ,  Andrei SONOC

IPC: H01J49/42

CPC classification number: H01J49/421

Abstract: An ion mass filter for use in a mass spectrometer is disclosed, which includes a plurality of rods arranged in a multipole configuration to provide a passageway through which ions can travel, said plurality of rods being configured for application of RF voltages thereto to generate an electromagnetic field within the passageway for providing radial confinement of the ions and further configured for application of a DC voltage thereto, and at least two pairs of auxiliary electrodes interspersed between the plurality of multipole rods, where one pair forms a first pole of the auxiliary electrodes and the other pair forms a second pole of the auxiliary electrodes. A controller can provide one or more control signals to the DC voltage source so as to switch the polarity of the DC voltage differential between the two poles according to a predefined criterion.

公开(公告)号：US20240355612A1

公开(公告)日：2024-10-24

申请号：US18685356

申请日：2022-08-23

Applicant: DH Technologies Development Pte. Ltd.

Inventor： David M. COX ,  Manuel FAUR ,  Mircea GUNA ,  Yang KANG ,  Andrei SONOC

IPC: H01J49/42 ,  H01J49/00

CPC classification number: H01J49/4215 ,  H01J49/004

Abstract: In one aspect, an ion filter for use in a mass spectrometer is disclosed, which includes a plurality of rods arranged in a multipole configuration to provide a passageway through which ions can travel, said plurality of rods being configured for application of RF voltages thereto to provide an electromagnetic field within the passageway for providing radial confinement of the ions and further configured for application of a DC voltage thereto. At least two pairs of auxiliary electrodes are interspersed between the plurality of rods and are configured for application of a DC bias voltage with one polarity to one of said pairs and a DC bias voltage with an opposite polarity to the other one of said pairs to provide a DC potential difference between the auxiliary electrodes and the plurality of rods.

公开(公告)号：US20240128069A1

公开(公告)日：2024-04-18

申请号：US18276609

申请日：2022-02-08

Applicant: DH Technologies Development Pte. Ltd.

Inventor： Mircea GUNA ,  Andrei SONOC

IPC: H01J49/00 ,  H01J49/06

CPC classification number: H01J49/005 ,  H01J49/0031 ,  H01J49/062

Abstract: In one aspect, a method of performing mass spectrometry is disclosed, which comprises introducing a plurality of ions into a mass spectrometer, selecting a portion of the precursor ions having m/z ratios within a first desired range to provide a plurality of precursor ions, causing fragmentation of at least a portion of the precursor ions to generate a plurality of product ions, selecting a portion of the product ions having m/z ratios within a second desired range, and performing mass analysis of the selected productions.