公开(公告)号：US09735001B2

公开(公告)日：2017-08-15

申请号：US14829454

申请日：2015-08-18

Applicant: FUDAN UNIVERSITY

Inventor： Chuanfan Ding ,  Li Ding

IPC: H01J49/06 ,  H01J49/42 ,  H01J49/00

CPC classification number: H01J49/4225 ,  H01J49/004 ,  H01J49/065 ,  H01J49/4235

Abstract: The invention “Ion Trap Array (ITA)” pertains generally to the field of ion storage and analysis technologies, and particularly to the ion storing apparatus and mass spectrometry instruments which separate ions by its character such as mass-to-charge ratio. The aim of this invention is providing an apparatus for ion storage and analysis comprising at least two or more rows of parallel placed electrode array wherein each electrode array includes at least two or more parallel bar-shaped electrodes, by applying different phase of alternating current voltages on different bar electrodes to create alternating electric fields inside the space between two parallel electrodes of different rows of electrode arrays, multiple linear ion trapping fields paralleled constructed in the space between the different rows of electrode arrays which are open to adjacent each other without a real barrier. This invention also provides a method for ion storage and analysis involving with the trapping, cooling and mass-selected analyzing of ions by this apparatus mentioned which constructs multiple conjoint linear ion trapping fields in the space between the different rows of electrode arrays.

公开(公告)号：US11912685B2

公开(公告)日：2024-02-27

申请号：US17468447

申请日：2021-09-07

Applicant: Fudan University

Inventor： Fener Chen ,  Chunlin Zhuang ,  Li Ding

IPC: C07D401/12 ,  C07D239/48 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12 ,  A61P31/18

CPC classification number: C07D401/12 ,  A61P31/18 ,  C07D239/48 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12

Abstract: This application provides a biphenyl diaryl pyrimidine derivative with an aromatic heterocyclic structure, a pharmaceutically-acceptable salt, a stereoisomer, a hydrate and a solvate thereof, where the biphenyl diaryl pyrimidine derivative is shown in formula (I). This application also provides a pharmaceutical composition containing the biphenyl diaryl pyrimidine derivative, or a pharmaceutically-acceptable salt, a stereoisomer, a hydrate and a solvate thereof, and a pharmaceutically-acceptable carrier. This application further provides a method of treating AIDS by administering a therapeutically effective amount of the pharmaceutical composition to a patient in need.