公开(公告)号：US12089932B2

公开(公告)日：2024-09-17

申请号：US17570235

申请日：2022-01-06

Applicant: Trace Matters Scientific LLC

Inventor： Mazdak Taghioskoui

IPC: A61B5/1473 ,  A61B5/00 ,  A61B10/04 ,  G01N27/622 ,  G01N33/483 ,  H01J49/00 ,  H01J49/06 ,  H01J49/16 ,  H01J49/36 ,  H01J49/42 ,  A61B18/00 ,  A61B18/24

CPC classification number: A61B5/1473 ,  A61B5/4842 ,  A61B10/04 ,  G01N27/622 ,  G01N33/4833 ,  H01J49/0013 ,  H01J49/0031 ,  H01J49/065 ,  H01J49/164 ,  H01J49/165 ,  H01J49/36 ,  H01J49/4235 ,  A61B2018/00577 ,  A61B18/24 ,  A61B2218/007 ,  A61B2503/40

Abstract: An ion transfer device that includes first and second ion guides, one or more RF voltage sources, and one or more DC voltage sources that produce first and second potential gradients in the first and second ion guides such that the potential gradients push the ions to move toward the outlet of each ion guide such that the one or more DC voltages produce a potential barrier, the potential barrier preventing the ions in the first ion guide from entering the second ion guide, the ions accumulate behind the potential barrier and form an ion packet, and the potential barrier is reduced after a predetermined time period to move the ion packet from the first ion guide to the second ion guide.

公开(公告)号：US11828724B2

公开(公告)日：2023-11-28

申请号：US16980990

申请日：2019-03-15

Applicant: THE UNIVERSITY OF LIVERPOOL (INCORPORATED IN THE UNITED KINGDOM)

Inventor： Simon Maher ,  Cedric Claude Boisdon

IPC: G01N27/622 ,  H01J49/06

CPC classification number: G01N27/622 ,  H01J49/062 ,  H01J49/065

Abstract: An ion guide electrode assembly (10) for an ion-mobility spectrometer is described. The electrode assembly (10) comprises a first sheet (100), having first and second surfaces (110, 120) comprising a plurality of corresponding regions (111, 112, 121, 122). The first sheet (100) comprises a set of N electrodes (130, 140), including a first electrode (130) and a second electrode (140), provided as tracks mutually spaced apart on the first surface (110) thereof. The electrode assembly (10) is arrangeable in a planar configuration and preferably in a tubular configuration. In the tubular configuration, a first part (131) of the first electrode (130), provided in a first region 111 of the first surface (110), overlays a second region (122) of the second surface (120). In the tubular configuration, the first part (131) of the first electrode (130) overlaps a second part (132) of the first electrode (130) and/or a second part (142) of the second electrode (140), provided in a second region (112) of the first surface (110).

公开(公告)号：US11756780B2

公开(公告)日：2023-09-12

申请号：US17541086

申请日：2021-12-02

Applicant: Thermo Finnigan LLC

Inventor： Harald Oser ,  Raman Mathur

IPC: H01J49/06 ,  H01J49/42

CPC classification number: H01J49/063 ,  H01J49/065 ,  H01J49/4225

Abstract: A first multipole assembly includes a first plurality of rod electrodes arranged about an axis and configured to confine ions radially about the axis. A second multipole assembly disposed adjacent to the first multipole assembly includes a second plurality of rod electrodes arranged about the axis and configured to confine the ions radially about the axis. An orientation of the first multipole assembly about the axis is rotationally offset relative to an orientation of the second multipole assembly about the axis.

公开(公告)号：US11728155B2

公开(公告)日：2023-08-15

申请号：US17612502

申请日：2020-05-19

Applicant: Thermo Fisher Scientific (Bremen) GmbH

Inventor： Henning Wehrs ,  Johannes Schwieters ,  Gerhard Jung

IPC: H01J49/06 ,  H01J49/02 ,  H01J49/00 ,  H01J49/10 ,  H01J49/42 ,  F16K1/20

CPC classification number: H01J49/063 ,  F16K1/2007 ,  H01J49/005 ,  H01J49/0077 ,  H01J49/022 ,  H01J49/065 ,  H01J49/067 ,  H01J49/068 ,  H01J49/105 ,  H01J49/421 ,  H01J49/4215

Abstract: An ion optical arrangement (1) for use in a mass spectrometer comprises electrodes (11, 12, 14) comprising a multipole arrangement defining an ion optical axis, and a voltage source for providing voltages to the electrodes to produce electric fields. The ion optical arrangement is configured for producing a radio frequency electric focusing field for focusing ions on the ion optical axis. The radio frequency electric focusing field has a varying frequency so as to reduce any mass dependence of ion trajectories through the ion optical arrangement. The ion optical arrangement may further be configured for producing a static electric field in response to a DC bias voltage applied to the multipole arrangement. A superimposed varying electric field may be produced by superimposing an AC voltage upon the DC bias voltage.

公开(公告)号：US20190234906A1

公开(公告)日：2019-08-01

申请号：US16383211

申请日：2019-04-12

Applicant: SensIT Ventures, Inc.

Inventor： Cristina E. Davis ,  Alexander A. Aksenov ,  Yuriy Zrodnikov

IPC: G01N27/62 ,  H01J49/42 ,  H01J49/06

CPC classification number: G01N27/624 ,  G01N27/622 ,  H01J49/062 ,  H01J49/065 ,  H01J49/4235 ,  Y10T29/49119

Abstract: One embodiment of the present disclosure provides an ion mobility spectrometry (IMS) device for performing chemical analysis. The IMS device includes a first set of electrodes arranged linearly in a first direction and separated by a first set of gaps. The IMS device also includes a second set of electrodes positioned directly opposing the first set of electrodes to match the first set of electrodes on a one-to-one basis, wherein the second set of electrodes are separated by a second set of gaps. The IMS device includes a drift region between the first set of electrodes and the second set of electrodes, wherein charged particles enter at a first end of the drift region and traverse the drift region along the first direction. The IMS device additionally includes a detector positioned at a second end of the drift region and configured to receive charged particles exiting the drift region.

公开(公告)号：US20190122875A1

公开(公告)日：2019-04-25

申请号：US16217377

申请日：2018-12-12

Applicant: Shimadzu Research Laboratory (Europe) Ltd.

Inventor： Alexander BERDNIKOV ,  Alina Andreyeva ,  Roger Giles

IPC: H01J49/00 ,  H01J49/06

CPC classification number: H01J49/0095 ,  H01J49/06 ,  H01J49/062 ,  H01J49/065

Abstract: The present invention is concerned with a device for charged particle transportation and manipulation. Embodiments provide a capability of combining positively and negatively charged particles in a single transported packet. Embodiments contain an aggregate of electrodes arranged to form a channel for transportation of charged particles, as well as a source of power supply that provides supply voltage to be applied to the electrodes, the voltage to ensure creation, inside the said channel, of a non-uniform high-frequency electric field, the pseudopotential of which field has one or more local extrema along the length of the channel used for charged particle transportation, at least, within a certain interval of time, whereas, at least one of the said extrema of the pseudopotential is transposed with time, at least within a certain interval of time, at least within a part of the length of the channel used for charged particle transportation.

公开(公告)号：US20180005811A1

公开(公告)日：2018-01-04

申请号：US15704366

申请日：2017-09-14

Applicant: Shimadzu Research Laboratory (Europe) Ltd.

Inventor： Alexander BERDNIKOV ,  Alina ANDREYEVA ,  Roger GILES

IPC: H01J49/00 ,  H01J49/06

CPC classification number: H01J49/0095 ,  H01J49/06 ,  H01J49/062 ,  H01J49/065

Abstract: The present invention is concerned with a device for charged particle transportation and manipulation. Embodiments provide a capability of combining positively and negatively charged particles in a single transported packet. Embodiments contain an aggregate of electrodes arranged to form a channel for transportation of charged particles, as well as a source of power supply that provides supply voltage to be applied to the electrodes, the voltage to ensure creation, inside the said channel, of a non-uniform high-frequency electric field, the pseudopotential of which field has one or more local extrema along the length of the channel used for charged particle transportation, at least, within a certain interval of time, whereas, at least one of the said extrema of the pseudopotential is transposed with time, at least within a certain interval of time, at least within a part of the length of the channel used for charged particle transportation.

公开(公告)号：US20170125230A1

公开(公告)日：2017-05-04

申请号：US15318858

申请日：2015-05-11

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Kiyomi Yoshinari ,  Yasushi Terui

IPC: H01J49/06 ,  H01J49/42 ,  H01J49/10

CPC classification number: H01J49/063 ,  H01J49/065 ,  H01J49/10 ,  H01J49/42 ,  H01J49/4215 ,  H01J49/4255

Abstract: The objective of the presently disclosed subject matter is to provide a mass spectrometer that improves the ionic permeability ratio at the entrance to an ion transport part or the entrance to a mass spectrometry part, and to acquire a high-sensitivity mass spectrum. To reduce the electric-field distortion that is caused by ion loss, electrodes are arranged so that the radius of a circle inscribed within the electrodes of the ion transport part is larger than the radius of a circle inscribed within the electrodes of the mass spectrometry part. The entrance to the electrodes of the mass spectrometry part also can have a tapered, inclined, folded-over, or rounded configuration. Together, these reduce the sharply fluctuating (peak-shaped) distribution of electric potential generated near the entrance to the ion transport part and the entrance to the mass spectrometry part.

公开(公告)号：US20170076929A1

公开(公告)日：2017-03-16

申请号：US15310694

申请日：2015-05-13

Applicant: MICROMASS UK LIMITED

Inventor： Kevin GILES ,  Jason Lee WILDGOOSE

IPC: H01J49/06 ,  H01J49/40 ,  H01J49/00

CPC classification number: H01J49/065 ,  H01J49/0027 ,  H01J49/004 ,  H01J49/40

Abstract: A method of mass spectrometry is disclosed comprising separating first ions according to a first physico-chemical property in a first separator wherein at least some of the first ions undergo a different number of cycles or passes within the separator and separating the first ions which emerge from the first separator according to a second physico-chemical property wherein the second physico-chemical property is correlated with the first physico-chemical property. The method further comprises determining the second physico-chemical property of the first ions and determining, assigning or de-convolving the first physico-chemical property of the first ions based upon the determined second physico-chemical property of the first ions.

Abstract translation: 公开了一种质谱法，其包括根据第一分离器中的第一物理化学性质分离第一离子，其中至少一些第一离子在分离器内经历不同数量的循环或通过，并分离出从 根据第二物理化学性质的第一分离器，其中第二物理化学性质与第一物理化学性质相关。 该方法还包括确定第一离子的第二物理化学性质，并基于所确定的第一离子的第二物理化学性质确定，分配或去卷积第一离子的第一物理化学性质。

公开(公告)号：US09558925B2

公开(公告)日：2017-01-31

申请号：US14256555

申请日：2014-04-18

Applicant: Battelle Memorial Institute

Inventor： Yehia M. Ibrahim ,  Richard D. Smith

IPC: H01J49/06

CPC classification number: H01J49/066 ,  H01J49/06 ,  H01J49/062 ,  H01J49/063 ,  H01J49/065

Abstract: A device for separating non-ions from ions is disclosed. The device includes a plurality of electrodes positioned around a center axis of the device and having apertures therein through which the ions are transmitted. An inner diameter of the apertures varies in length. At least a portion of the center axis between the electrodes is non-linear.

Abstract translation: 公开了一种用于从离子离子分离的装置。 该装置包括围绕该装置的中心轴定位的多个电极，并且其中具有孔，离子通过该孔传输。 孔径的内径长度变化。 电极之间的中心轴的至少一部分是非线性的。