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    AN APPARATUS AND METHOD FOR DETECTING PHOTOLUMINESCENT LIGHT EMITTED FROM A SAMPLE
    1.
    发明申请
    AN APPARATUS AND METHOD FOR DETECTING PHOTOLUMINESCENT LIGHT EMITTED FROM A SAMPLE 有权

    公开(公告)号：US20220113254A1

    公开(公告)日：2022-04-14

    申请号：US17428607

    申请日：2020-02-14

    Applicant: IMEC VZW

    Inventor： Finub JAMES SHIRLEY ,  Pol VAN DORPE

    IPC: G01N21/64 ,  G01N21/49

    Abstract: The present invention provides an apparatus for detecting photoluminescent light emitted from a sample, said apparatus (200; 300) comprising at least one light source (210; 310, 318), which is configured to emit light of a first and a second wavelength towards a sample comprising photoluminescent particles, wherein said first wavelength is an excitation wavelength for inducing photo-luminescent light from said photoluminescent particles, and wherein said second wavelength is longer than said first wavelength and for gathering background noise information from said sample. The apparatus further comprises a photo-detector (206) for detecting light incident on the photo-detector (206); and an interference filter (204; 304) arranged on the photo-detector (206), wherein the interference filter (204; 304) is configured to selectively collect and transmit light towards the photo-detector (206) based on an angle of incidence of the light towards the interference filter (204; 304), wherein the interference filter (204; 304) is configured to selectively transmit supercritical angle light from the sample towards the photo-detector (206) and suppress undercritical angle light from the sample.

    LIGHT TRANSMISSION SYSTEM FOR DELIVERING LIGHT TO A RAMAN SPECTROMETER
    2.
    发明申请
    LIGHT TRANSMISSION SYSTEM FOR DELIVERING LIGHT TO A RAMAN SPECTROMETER 有权

    公开(公告)号：US20220003602A1

    公开(公告)日：2022-01-06

    申请号：US17368660

    申请日：2021-07-06

    Applicant: IMEC VZW

    Inventor： Kirill ZINOVIEV ,  Pol VAN DORPE

    IPC: G01J3/10 ,  G01N21/35 ,  G01N21/65 ,  G01J3/44

    Abstract: According to an aspect of the present inventive concept there is provided a light transmission system (100, 200) for delivering light to a Raman spectrometer (20), the system comprising: a homogenizer (110, 510) with an entrance surface (112, 512) having an entrance height and an entrance width, an exit surface (114, 514) having an exit height and an exit width, and wherein the exit height is of a larger size than the entrance height; and wherein the homogenizer (110, 510) is configured to receive, at the entrance surface (112, 512), light from a bundle (210) of optical fibers (220) and wherein each fiber (220) in the bundle (210) defines an entrance divergence angle of light; and wherein the homogenizer (110, 510) is configured to transmit light such that an exit divergence angle of light, in a plane parallel with a direction of the exit height, is smaller than the entrance divergence angle of light, in a plane parallel with a direction of the entrance height.

    IMAGING SYSTEM AND A METHOD FOR IMAGING A SAMPLE
    5.
    发明申请
    IMAGING SYSTEM AND A METHOD FOR IMAGING A SAMPLE 有权

    公开(公告)号：US20230010628A1

    公开(公告)日：2023-01-12

    申请号：US17856063

    申请日：2022-07-01

    Applicant: IMEC VZW

    Inventor： Pol VAN DORPE

    IPC: G03H1/04 ,  G03H1/08 ,  G03H1/22 ,  G01N21/47

    Abstract: According to an aspect of the present inventive concept there is provided an imaging system for imaging of a sample, comprising a light source, an interference filter and a detector, the light source generates illumination light of a single wavelength to induce elastic scattering of the light by the sample, the interference filter selectively reduces transmittance of light having an incident angle on the interference filter corresponding to non-scattered light, the detector is configured to detect a two-dimensional representation of the elastically scattered light transmitted by the interference filter.

    LIGHT EXCITATION AND COLLECTION DEVICE AND A METHOD FOR LIGHT EXCITATION AND COLLECTION
    6.
    发明申请
    LIGHT EXCITATION AND COLLECTION DEVICE AND A METHOD FOR LIGHT EXCITATION AND COLLECTION 有权

    公开(公告)号：US20220178812A1

    公开(公告)日：2022-06-09

    申请号：US17544300

    申请日：2021-12-07

    Applicant: IMEC VZW

    Inventor： Niels VERELLEN ,  Pol VAN DORPE

    IPC: G01N15/14

    Abstract: According to an aspect of the present inventive concept there is provided a light excitation and collection device for a micro-fluidic system, comprising: a light source configured to generate excitation light; a plurality of excitation waveguides, each associated with a flow channel of the micro-fluidic system; wherein each excitation waveguide is configured to receive and redirect the excitation light towards the flow channel, such that the excitation light is elastically scattered by a sample in the flow channel forming forward and side scattered light; and wherein the light excitation and collection device further comprises: at least one forward scattered light collection point; and at least one side scattered light collection point; and wherein the forward scattered light collected for all excitation waveguides is detected by a first plurality of light sensitive areas and the side scattered light collected for all excitation waveguides is detected by a second plurality of light sensitive areas, the first and the second pluralities of light sensitive areas form different groups of light sensitive areas.

    LIGHT EXCITATION AND COLLECTION DEVICE AND A METHOD FOR LIGHT EXCITATION AND COLLECTION
    7.
    发明申请
    LIGHT EXCITATION AND COLLECTION DEVICE AND A METHOD FOR LIGHT EXCITATION AND COLLECTION 有权

    公开(公告)号：US20240410815A1

    公开(公告)日：2024-12-12

    申请号：US18808756

    申请日：2024-08-19

    Applicant: IMEC VZW

    Inventor： Niels VERELLEN ,  Pol VAN DORPE

    IPC: G01N15/14 ,  G01N15/10 ,  G01N15/1434 ,  G01N15/1492

    Abstract: According to an aspect of the present inventive concept there is provided a light excitation and collection device for a micro-fluidic system, comprising: a light source configured to generate excitation light; a plurality of excitation waveguides, each associated with a flow channel of the micro-fluidic system; wherein each excitation waveguide is configured to receive and redirect the excitation light towards the flow channel, such that the excitation light is elastically scattered by a sample in the flow channel forming forward and side scattered light; and wherein the light excitation and collection device further comprises: at least one forward scattered light collection point; and at least one side scattered light collection point; and wherein the forward scattered light collected for all excitation waveguides is detected by a first plurality of light sensitive areas and the side scattered light collected for all excitation waveguides is detected by a second plurality of light sensitive areas, the first and the second pluralities of light sensitive areas form different groups of light sensitive areas.

    METHOD OF OPERATING A PORE FIELD-EFFECT TRANSISTOR SENSOR FOR DETECTING PARTICLES
    8.
    发明申请
    METHOD OF OPERATING A PORE FIELD-EFFECT TRANSISTOR SENSOR FOR DETECTING PARTICLES 有权

    公开(公告)号：US20230003710A1

    公开(公告)日：2023-01-05

    申请号：US17849905

    申请日：2022-06-27

    Applicant: IMEC VZW

    Inventor： Anne VERHULST ,  Pol VAN DORPE

    IPC: G01N33/487 ,  G01N15/06

    Abstract: A method of operating a pore field-effect transistor (FET) sensor for detecting particles, wherein the pore FET sensor comprises a FET wherein a gate is controlled by a pore filled by a fluid, comprises: controlling a first voltage (Vcis) to set the FET in a subthreshold region; controlling a second voltage (Vtrans) to set a voltage difference between the first and second voltages (Vtrans) such that an effective difference in gate voltage experienced between a minimum and a maximum effective gate voltage during movement of a particle in the fluid is at least kT/q; and detecting a drain-source current in the FET, wherein the particle passing through the pore modulates the drain-source current for detecting presence of the particle.

    Illuminator, an imaging apparatus and a system
    9.
    发明申请
    Illuminator, an imaging apparatus and a system 有权

    公开(公告)号：US20210191100A1

    公开(公告)日：2021-06-24

    申请号：US17107974

    申请日：2020-12-01

    Applicant: IMEC VZW

    Inventor： Pol VAN DORPE

    IPC: G02B21/36 ,  G02B21/02

    Abstract: An illuminator, comprising: an illumination waveguide, and a controller; the illumination waveguide being a planar waveguide configured to receive a light wave at a receiving end and guide it to a mirror end; the mirror end comprising a patterned mirror configured to reflect at least part of the light wave back into the illumination waveguide, the patterned mirror comprising a pattern configured to confer a diffraction pattern to the reflected light, the diffraction pattern contributing to an interference pattern, the interference pattern having an evanescent field outside the illumination waveguide, wherein the evanescent field of the interference pattern is configured to illuminate an object in close relation to the illumination waveguide; wherein the controller is configured to control a wavefront of the received light wave and to set a relation between the controlled wavefront and the pattern of the patterned mirror such that the interference pattern forms at least one element of constructive interference for selectively illuminating a portion of the object; wherein the controller is further configured to sequentially change the interference pattern.

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