公开(公告)号：US11781912B2

公开(公告)日：2023-10-10

申请号：US17536068

申请日：2021-11-28

Applicant: MIFTEK CORPORATION

Inventor： Masanobu Yamamoto ,  Keegan Hernandez ,  J. Paul Robinson

IPC: G01J3/44 ,  G01J3/02

CPC classification number: G01J3/4406 ,  G01J3/0218 ,  G01J3/0227

Abstract: A measurement system includes an optical source (e.g., laser) to irradiate a sample (e.g., a cell); a solid-state photon detector (SSPD) to receive resultant light from the sample; and a photon counter to count photons received by the SSPD. The photon counter can include a differentiator to provide a differentiated photon signal and a crossing detector configured to count photons based on a number of times the differentiated photon signal crosses a predetermined threshold level. In some examples, a pulse detector can provide a pulse-width signal from the SSPD output photon signal, and a pulse counter can count based on both a number of pulses and widths of the pulses. The SSPD can include a silicon photomultiplier (SiPM) array or a solid-state photomultiplier. Some examples use the measurement system to measure samples in fluids, e.g., in flow cytometers or multi-well plates.

公开(公告)号：US20230296511A1

公开(公告)日：2023-09-21

申请号：US18042220

申请日：2021-08-19

Applicant: Maytronics Ltd.

Inventor： Hanoch KISLEV ,  Shahar SOBOL ,  Yehonatan Evgeniy TILCHIN ,  Alexander RACHMAN

IPC: G01N21/51 ,  G01N21/31 ,  G01N21/64 ,  G01J3/42 ,  G01J3/02 ,  G01J3/28

CPC classification number: G01N21/51 ,  G01N21/31 ,  G01N21/64 ,  G01J3/42 ,  G01J3/0208 ,  G01J3/0213 ,  G01J3/0227 ,  G01J3/2803

Abstract: A liquid measuring system (LMS) comprising: a light source; a multi-region optical filter (MROF); a sample cell configured to contain a liquid sample; an optical detection subsystem (ODS) having an optical detector for measuring optical properties of light emanating from the liquid sample. The MROF may include a spectral filter region such as a bandpass or a long-pass filter type region, and natural density (ND) type filter region, for enabling simultaneous optical measuring at least of turbidity level and algae concentration in a water sample contained by the sample cell, by having light passed through the water sample and the MROF before reaching the optical detector of the ODS. Embodiments of the MROFs may be also used, for example for selective spectral attenuation of light illuminating the liquid sample to achieve reduction in distortions due to stray light.

公开(公告)号：US09791375B2

公开(公告)日：2017-10-17

申请号：US14668500

申请日：2015-03-25

Applicant: FUJIFILM Corporation

Inventor： Shogo Yamazoe ,  Masayuki Naya ,  Megumi Shiota

IPC: G01J3/44 ,  G01N21/00 ,  G01N21/65 ,  G01B11/14 ,  G01J3/02

CPC classification number: G01N21/658 ,  G01B11/14 ,  G01J3/0227 ,  G01J3/4412 ,  G01N2201/0612

Abstract: Using an optical electric field enhancing device including a fine uneven structure made of gold formed on the front surface of a transparent substrate, illumination light of a wavelength in the range from 400 to 530 nm is applied at least to an analyte, positional information of the analyte is detected by a position detection unit disposed on the rear surface side of the optical electric field enhancing device, and excitation light is applied to the detected position by an excitation light application unit. Signal light emitted from the analyte when the excitation light is applied is detected from the rear surface side of the transparent substrate.

公开(公告)号：US20170146711A1

公开(公告)日：2017-05-25

申请号：US15168395

申请日：2016-05-31

Applicant: AGENCY FOR DEFENSE DEVELOPMENT

Inventor： Yeon-Chul HA ,  Jae-Hwan LEE ,  Young-Su JEONG ,  Sun-Kyung CHOI ,  Young-Jin KOH

IPC: G02B5/28 ,  C23C14/10 ,  C23C14/46 ,  C23C14/08 ,  G01J3/02 ,  G01J3/44

CPC classification number: G02B5/283 ,  C23C14/081 ,  C23C14/10 ,  C23C14/46 ,  G01J3/0205 ,  G01J3/0227 ,  G01J3/44 ,  G01J3/4412 ,  G02B5/285

Abstract: A Raman edge filter and a method of manufacturing the same, wherein in order to obtain a Raman spectrum for compound analysis in a Raman spectrometer using a deep-ultraviolet ray (UV) laser, the Raman edge filter functions to eliminate a deep-UV laser wavelength, which is a light source, and to transmit Raman scattered light.

公开(公告)号：US20170138790A1

公开(公告)日：2017-05-18

申请号：US15321756

申请日：2015-06-29

Applicant: Spectral Engines Oy

Inventor： Jarkko Antila ,  Uula Kantojärvi ,  Altti Akujärvi ,  Mikko Tuohiniemi ,  Jussi Mäkynen

IPC: G01J3/02 ,  G01J3/45 ,  G01J3/26

CPC classification number: G01J3/0297 ,  G01J3/0227 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/0286 ,  G01J3/26 ,  G01J3/28 ,  G01J3/45 ,  G01J2003/2879 ,  G02B26/001

Abstract: A method for determining spectral calibration data (λcal(Sd), Sd,cal(λ)) of a Fabry-Perot interferometer (100) comprises: forming a plurality of filtered spectral peaks (P′1, P′2) by filtering input light (LB1) with a Fabry-Perot etalon (50) such that a first filtered peak (P′1) corresponds to a first transmittance peak (P1) of the etalon (50), and such that a second filtered peak (P′2) corresponds to a second transmittance peak (P1) of the etalon (50), using the Fabry-Perot interferometer (100) for measuring a spectral intensity distribution (M(Sd)) of the filtered spectral peaks (P′1, P′2), wherein the spectral intensity distribution (M(Sd)) is measured by varying the mirror gap (dFP) of the Fabry-Perot interferometer (100), and by providing a control signal (Sd) indicative of the mirror gap (dFP), and determining the spectral calibration data (λcal(Sd), Sd,cal(λ)) by matching the measured spectral intensity distribution (M(Sd)) with the spectral transmittance (TE(λ)) of the etalon (50).

公开(公告)号：US09295420B2

公开(公告)日：2016-03-29

申请号：US14327553

申请日：2014-07-09

Applicant: Hong Kong Applied Science and Technology Research Institute Co. Ltd.

Inventor： Chun Zhang ,  Ka Cheung Kwok ,  Lydia Lap Wai Leung

IPC: G01J3/44 ,  A61B5/1455 ,  G01N21/63 ,  A61B5/00 ,  G01N21/65 ,  G01J3/02

CPC classification number: A61B5/1455 ,  A61B5/0075 ,  G01J3/0202 ,  G01J3/0216 ,  G01J3/0227 ,  G01J3/0237 ,  G01J3/06 ,  G01J3/44 ,  G01N21/63 ,  G01N21/65 ,  G01N2201/06113

Abstract: A transmission-reflectance swappable Raman device and a method thereof are disclosed. The excitation light is selectively directed to the sample in one direction for generating the transmission Raman signal in transmission mode or in another direction for generating the reflectance Raman signal in reflectance mode. The content of an analyte in a sample can be determined by analyzing transmission and reflectance Raman signal.

Abstract translation: 公开了一种透射反射可交换拉曼装置及其方法。 激发光在一个方向上选择性地导向样品，以在透射模式或另一方向上产生透射拉曼信号，以在反射模式下产生反射拉曼信号。 可以通过分析透射和反射拉曼信号来确定样品中分析物的含量。

公开(公告)号：US09176279B2

公开(公告)日：2015-11-03

申请号：US14373417

申请日：2012-04-25

Applicant: Charles M. Santori ,  Di Liang ,  Marco Fiorentino ,  David A. Fattal ,  Zhen Peng ,  Raymond G. Beausoleil ,  Andrei Faraon

Inventor： Charles M. Santori ,  Di Liang ,  Marco Fiorentino ,  David A. Fattal ,  Zhen Peng ,  Raymond G. Beausoleil ,  Andrei Faraon

IPC: G02B6/00 ,  G02B6/26 ,  G02B6/42 ,  G02B6/34 ,  G01J3/40 ,  G01J3/28 ,  G01J3/45 ,  G02B6/28 ,  G01J3/18 ,  G02F1/21 ,  G02B6/12 ,  G01J3/02 ,  G01J3/44

CPC classification number: G02B6/2813 ,  G01J3/0227 ,  G01J3/0259 ,  G01J3/1895 ,  G01J3/2823 ,  G01J3/4412 ,  G01J3/45 ,  G02B2006/12152 ,  G02F2001/217

Abstract: Apparatuses and systems for analyzing light by mode interference are provided. An example of an apparatus for analyzing light by mode interference includes a number of waveguides to support in a multimode region two modes of the light of a particular polarization and a plurality of scattering objects offset from a center of at least one of the number of waveguides.

Abstract translation: 提供了通过模式干扰分析光的装置和系统。 用于通过模式干扰来分析光的装置的示例包括多个波导中的多个波导，所述波导在多模区域中支持特定偏振光的两种模式和从波导数的至少一个的中心偏移的多个散射物体 。

公开(公告)号：US08912494B2

公开(公告)日：2014-12-16

申请号：US13211413

申请日：2011-08-17

Applicant: James A. Chervenak ,  Ari D. Brown ,  Edward J. Wollack ,  Dominic J. Benford

Inventor： James A. Chervenak ,  Ari D. Brown ,  Edward J. Wollack ,  Dominic J. Benford

IPC: G01J5/00 ,  G01J3/02 ,  G01J5/08 ,  G01J3/42 ,  G01J5/20 ,  G01N21/35

CPC classification number: G01J3/0227 ,  G01J3/42 ,  G01J5/0828 ,  G01J5/0837 ,  G01J5/20 ,  G01N21/3581

Abstract: An apparatus for ultrasensitive long-wave imaging cameras is provided. In one embodiment, the apparatus includes a filter configured to allow high frequencies of interest to pass through the filter. The apparatus also includes an antenna that is configured to receive the high frequencies of interest. The apparatus further includes a plurality of bolometers that are configured to measure data regarding the high frequencies of interest.

Abstract translation: 提供了一种用于超灵敏长波成像相机的设备。 在一个实施例中，该装置包括被配置为允许感兴趣的高频通过滤波器的滤波器。 该装置还包括被配置为接收感兴趣的高频的天线。 该装置还包括多个测辐射热计，其配置成测量关于感兴趣的高频的数据。

公开(公告)号：US20140362374A1

公开(公告)日：2014-12-11

申请号：US14373417

申请日：2012-04-25

Applicant: Charles M. Santori ,  Marco Fiorentino ,  David A. Fattal ,  Zhen Peng ,  Raymond G. Beausoleil ,  Di Liang ,  Andrei Faraon

Inventor： Charles M. Santori ,  Marco Fiorentino ,  David A. Fattal ,  Zhen Peng ,  Raymond G. Beausoleil ,  Di Liang ,  Andrei Faraon

IPC: G01J3/44

CPC classification number: G02B6/2813 ,  G01J3/0227 ,  G01J3/0259 ,  G01J3/1895 ,  G01J3/2823 ,  G01J3/4412 ,  G01J3/45 ,  G02B2006/12152 ,  G02F2001/217

Abstract: Apparatuses and systems for analyzing light by mode interference are provided. An example of an apparatus for analyzing light by mode interference includes a number of waveguides to support in a multimode region two modes of the light of a particular polarization and a plurality of scattering objects offset from a center of at least one of the number of waveguides.

Abstract translation: 提供了通过模式干扰分析光的装置和系统。 用于通过模式干扰来分析光的装置的示例包括多个波导中的多个波导，所述波导在多模区域中支持特定偏振光的两种模式和从波导数的至少一个的中心偏移的多个散射物体 。

公开(公告)号：US08675191B2

公开(公告)日：2014-03-18

申请号：US13773623

申请日：2013-02-21

Applicant: Board of Regents of the University of Texas System ,  Michigan Technological University

Inventor： Manfred Fink ,  Philip Varghese ,  Jacek Borysow

IPC: G01J3/44

CPC classification number: G01J3/44 ,  A61B5/0075 ,  A61B5/0836 ,  A61B5/7257 ,  G01J3/02 ,  G01J3/0227 ,  G01J3/0232 ,  G01N21/65

Abstract: A Raman analyzer for analyzing light emitted from a Raman cell is provided that has a beam splitter configured to split the light emitted from the Raman cell into a first beam and a second beam. An atomic vapor filter can be used to filter a Raman scattered line from the first beam and a chopper system can periodically interrupt the first and second beams that are directed towards a photo detector, which can convert light from the first and second beams into an electrical signal. The signal output from the photo detector can optionally be amplified, digitized, Fourier filtered, and/or subjected to Fourier analysis.

Abstract translation: 提供了用于分析从拉曼单元发射的光的拉曼分析器，其具有分束器，其被配置为将从拉曼单元发射的光分成第一光束和第二光束。 可以使用原子蒸汽过滤器来从第一光束过滤拉曼散射线，并且斩波系统可以周期性地中断指向光电检测器的第一和第二光束，其可以将来自第一和第二光束的光转换成电 信号。 从光电检测器输出的信号可以可选地被放大，数字化，傅里叶滤波和/或进行傅立叶分析。