公开(公告)号：US20180313691A1

公开(公告)日：2018-11-01

申请号：US15921517

申请日：2018-03-14

Applicant: KLEIN MEDICAL LIMITED

Inventor： Raymond Andrew Simpkin ,  Donal Paul Krouse ,  Bryan James Smith

IPC: G01J3/10 ,  G01N21/3577 ,  G01N21/27 ,  G01N21/359 ,  G01J3/02 ,  G01J3/28

CPC classification number: G01J3/108 ,  G01J3/0297 ,  G01J3/28 ,  G01N21/274 ,  G01N21/3577 ,  G01N21/359 ,  G01N2201/0691

Abstract: A method and analyser for identifying or verifying or otherwise characterising a sample comprising: using or having an electromagnetic radiation source for emitting electromagnetic radiation in at least one beam at a sample, the electromagnetic radiation comprising at least two different wavelengths, using or having a sample detector that detects affected electromagnetic radiation resulting from the emitted electromagnetic radiation affected by the sample and provides output representing the detected affected radiation, and using or having a processor for determining sample coefficients from the output, and identifying or verifying or otherwise characterising the sample using the sample coefficients and training coefficients determined from training samples, wherein the coefficients reduce sensitivity to a sample retainer variation and/or are independent of concentration.

公开(公告)号：US10066993B2

公开(公告)日：2018-09-04

申请号：US15620693

申请日：2017-06-12

Applicant: KLEIN MEDICAL LIMITED

Inventor： Raymond Andrew Simpkin ,  Donal Paul Krouse ,  Bryan James Smith

IPC: G01J5/02 ,  G01J3/10 ,  G01N21/3577 ,  G01N21/27 ,  G01J3/02 ,  G01N21/359 ,  G01J3/28

Abstract: A method and analyser for identifying or verifying or otherwise characterising a sample comprising: using or having an electromagnetic radiation source for emitting electromagnetic radiation in at least one beam at a sample, the electromagnetic radiation comprising at least two different wavelengths, using or having a sample detector that detects affected electromagnetic radiation resulting from the emitted electromagnetic radiation affected by the sample and provides output representing the detected affected radiation, and using or having a processor for determining sample coefficients from the output, and identifying or verifying or otherwise characterising the sample using the sample coefficients and training coefficients determined from training samples, wherein the coefficients reduce sensitivity to a sample retainer variation and/or are independent of concentration.

公开(公告)号：US09354165B2

公开(公告)日：2016-05-31

申请号：US14409450

申请日：2013-06-19

Applicant: KLEIN MEDICAL LIMITED

Inventor： Raymond Andrew Simpkin ,  Donal Paul Krouse ,  Bryan James Smith

IPC: G01J5/02 ,  G01N21/359 ,  G01N21/31 ,  G01N21/27 ,  G01N21/3577 ,  G01J3/28

CPC classification number: G01J3/108 ,  G01J3/0297 ,  G01J3/28 ,  G01N21/274 ,  G01N21/3577 ,  G01N21/359 ,  G01N2201/0691

Abstract: A method and analyzer for identifying, verifying or otherwise characterizing a sample involves emitting electromagnetic radiation in at least one beam at a sample. The electromagnetic radiation includes at least two different wavelengths. A sample detector detects affected electromagnetic radiation resulting from the emitted electromagnetic radiation affected by the sample and provides output representing the detected affected radiation. A processor determines sample coefficients from the output and identifies, verifies or otherwise characterizes the sample using the sample coefficients and training coefficients determined from training samples. The coefficients reduce sensitivity to a sample retainer variation and/or are independent of concentration.

Abstract translation: 用于识别，验证或以其他方式表征样品的方法和分析仪包括在样品的至少一个束中发射电磁辐射。 电磁辐射包括至少两个不同的波长。 样品检测器检测受样品发射的电磁辐射产生的电磁辐射，并提供表示检测到的受影响辐射的输出。 处理器从输出端确定采样系数，并使用从训练样本确定的采样系数和训练系数来识别，验证或以其他方式表征样本。 系数降低了对样品保持器变化的敏感性和/或不依赖于浓度。

公开(公告)号：US20150144791A1

公开(公告)日：2015-05-28

申请号：US14409450

申请日：2013-06-19

Applicant: KLEIN MEDICAL LIMITED

Inventor： Raymond Andrew Simpkin ,  Donal Paul Krouse ,  Bryan James Smith

IPC: G01N21/359

CPC classification number: G01J3/108 ,  G01J3/0297 ,  G01J3/28 ,  G01N21/274 ,  G01N21/3577 ,  G01N21/359 ,  G01N2201/0691

Abstract: A method and analyser for identifying, verifying or otherwise characterising a sample involves emitting electromagnetic radiation in at least one beam at a sample. The electromagnetic radiation includes at least two different wavelengths. A sample detector detects affected electromagnetic radiation resulting from the emitted electromagnetic radiation affected by the sample and provides output representing the detected affected radiation. A processor determines sample coefficients from the output and identifies, verifies or otherwise characterises the sample using the sample coefficients and training coefficients determined from training samples. The coefficients reduce sensitivity to a sample retainer variation and/or are independent of concentration.

Abstract translation: 用于识别，验证或以其他方式表征样品的方法和分析仪包括在样品的至少一个束中发射电磁辐射。 电磁辐射包括至少两个不同的波长。 样品检测器检测受样品发射的电磁辐射产生的电磁辐射，并提供表示检测到的受影响辐射的输出。 处理器从输出端确定采样系数，并使用从训练样本确定的采样系数和训练系数来识别，验证或以其他方式表征样本。 系数降低了对样品保持器变化的敏感性和/或不依赖于浓度。

公开(公告)号：US10241039B2

公开(公告)日：2019-03-26

申请号：US15377914

申请日：2016-12-13

Applicant: Klein Medical Limited

Inventor： Donal Paul Krouse ,  Raymond Andrew Simpkin ,  Bryan James Smith

IPC: G01N21/35 ,  G01J3/10 ,  G01J3/28 ,  G01J3/42 ,  G01N21/84 ,  G01N21/3577 ,  G01N21/359 ,  G01J3/12

Abstract: An analyser 10 for identifying or verifying or otherwise characterising a liquid based drug sample 16 comprising: an electromagnetic radiation source 11 for emitting electromagnetic radiation 14a in at least one beam at a sample 16, the electromagnetic radiation comprising at least two different wavelengths, a sample detector 17 that detects affected electromagnetic radiation resulting from the emitted electromagnetic radiation affected by the sample, and a processor 18 for identifying or verifying the sample from the detected affected electromagnetic radiation, wherein each wavelength or at least two of the wavelengths is between substantially 1300 nm and 2000 nm, and each wavelength or at least two of the wavelengths is in the vicinity of the wavelength(s) of (or within a region spanning) a spectral characteristic in the liquid spectrum between substantially 1300 nm and 2000 nm.

公开(公告)号：US20180017442A1

公开(公告)日：2018-01-18

申请号：US15620693

申请日：2017-06-12

Applicant: Klein Medical Limited

Inventor： Raymond Andrew Simpkin ,  Donal Paul Krouse ,  Bryan James Smith

IPC: G01J3/10 ,  G01N21/359 ,  G01J3/02 ,  G01N21/3577 ,  G01N21/27 ,  G01J3/28

CPC classification number: G01J3/108 ,  G01J3/0297 ,  G01J3/28 ,  G01N21/274 ,  G01N21/3577 ,  G01N21/359 ,  G01N2201/0691

Abstract: A method and analyser for identifying or verifying or otherwise characterising a sample comprising: using or having an electromagnetic radiation source for emitting electromagnetic radiation in at least one beam at a sample, the electromagnetic radiation comprising at least two different wavelengths, using or having a sample detector that detects affected electromagnetic radiation resulting from the emitted electromagnetic radiation affected by the sample and provides output representing the detected affected radiation, and using or having a processor for determining sample coefficients from the output, and identifying or verifying or otherwise characterising the sample using the sample coefficients and training coefficients determined from training samples, wherein the coefficients reduce sensitivity to a sample retainer variation and/or are independent of concentration.

公开(公告)号：US20190317016A1

公开(公告)日：2019-10-17

申请号：US16269418

申请日：2019-02-06

Applicant: Klein Medical Limited

Inventor： Donal Paul Krouse ,  Raymond Andrew Simpkin ,  Bryan James Smith

IPC: G01N21/3577 ,  G01J3/28 ,  G01J3/42 ,  G01J3/10 ,  G01N21/84 ,  G01N21/359

Abstract: An analyser 10 for identifying or verifying or otherwise characterising a liquid based drug sample 16 comprising: an electromagnetic radiation source 11 for emitting electromagnetic radiation 14a in at least one beam at a sample 16, the electromagnetic radiation comprising at least two different wavelengths, a sample detector 17 that detects affected electromagnetic radiation resulting from the emitted electromagnetic radiation affected by the sample, and a processor 18 for identifying or verifying the sample from the detected affected electromagnetic radiation, wherein each wavelength or at least two of the wavelengths is between substantially 1300 nm and 2000 nm, and each wavelength or at least two of the wavelengths is in the vicinity of the wavelength(s) of (or within a region spanning) a spectral characteristic in the liquid spectrum between substantially 1300 nm and 2000 nm.

公开(公告)号：US10352768B2

公开(公告)日：2019-07-16

申请号：US15921517

申请日：2018-03-14

Applicant: KLEIN MEDICAL LIMITED

Inventor： Raymond Andrew Simpkin ,  Donal Paul Krouse ,  Bryan James Smith

IPC: G01J5/02 ,  G01J3/10 ,  G01N21/27 ,  G01N21/3577 ,  G01N21/359 ,  G01J3/02 ,  G01J3/28

Abstract: A method and analyzer for identifying or verifying or otherwise characterizing a sample comprising: using or having an electromagnetic radiation source for emitting electromagnetic radiation in at least one beam at a sample, the electromagnetic radiation comprising at least two different wavelengths, using or having a sample detector that detects affected electromagnetic radiation resulting from the emitted electromagnetic radiation affected by the sample and provides output representing the detected affected radiation, and using or having a processor for determining sample coefficients from the output, and identifying or verifying or otherwise characterizing the sample using the sample coefficients and training coefficients determined from training samples, wherein the coefficients reduce sensitivity to a sample retainer variation and/or are independent of concentration.

公开(公告)号：US20170184494A1

公开(公告)日：2017-06-29

申请号：US15377914

申请日：2016-12-13

Applicant: Klein Medical Limited

Inventor： Donal Paul Krouse ,  Raymond Andrew Simpkin ,  Bryan James Smith

IPC: G01N21/3577 ,  G01N21/359

CPC classification number: G01N21/3577 ,  G01J3/10 ,  G01J3/28 ,  G01J3/42 ,  G01J2003/1286 ,  G01N21/359 ,  G01N21/84 ,  G01N2021/3595 ,  G01N2201/0612 ,  G01N2201/0691

Abstract: An analyser 10 for identifying or verifying or otherwise characterising a liquid based drug sample 16 comprising: an electromagnetic radiation source 11 for emitting electromagnetic radiation 14a in at least one beam at a sample 16, the electromagnetic radiation comprising at least two different wavelengths, a sample detector 17 that detects affected electromagnetic radiation resulting from the emitted electromagnetic radiation affected by the sample, and a processor 18 for identifying or verifying the sample from the detected affected electromagnetic radiation, wherein each wavelength or at least two of the wavelengths is between substantially 1300 nm and 2000 nm, and each wavelength or at least two of the wavelengths is in the vicinity of the wavelength(s) of (or within a region spanning) a spectral characteristic in the liquid spectrum between substantially 1300 nm and 2000 nm.

公开(公告)号：US09625377B2

公开(公告)日：2017-04-18

申请号：US15056907

申请日：2016-02-29

Applicant: KLEIN MEDICAL LIMITED

Inventor： Bryan James Smith ,  Donal Paul Krouse ,  Raymond Andrew Simpkin

IPC: G01N33/48 ,  G01N21/359 ,  G01J3/10 ,  G01J3/42 ,  G01N21/3577 ,  G01J3/28 ,  G01N21/84 ,  G01J3/12 ,  G01N21/35

CPC classification number: G01N21/3577 ,  G01J3/10 ,  G01J3/28 ,  G01J3/42 ,  G01J2003/1286 ,  G01N21/359 ,  G01N21/84 ,  G01N2021/3595 ,  G01N2201/0612 ,  G01N2201/0691

Abstract: An analyser and related methods for characterising a sample. The analyser includes an integrated laser for emitting electromagnetic radiation in at least one beam at a sample. The electromagnetic radiation can include at least two different wavelengths. A sample detector detects affected electromagnetic radiation resulting from the emitted electromagnetic radiation affected by the sample and provides output representing the detected affected radiation. The analyser also includes a processor for characterising the sample from the detector output representing the detected affected electromagnetic radiation.