公开(公告)号：US20170266317A1

公开(公告)日：2017-09-21

申请号：US15458925

申请日：2017-03-14

Applicant: Massachusetts Institute of Technology ,  University of North Carolina Chapel Hill

Inventor： Roberta Polak ,  Robert E. Cohn ,  Michael F. Rubner ,  Elena V. Batrakova ,  Matthew J. Haney ,  Natalya L. Klyachko ,  Yuling Zhao

IPC: A61K47/48 ,  A61K35/15 ,  A61K38/44 ,  A61K9/70

CPC classification number: C12Y111/01006 ,  A61K35/15 ,  A61K35/28 ,  A61K38/44 ,  A61K47/6815 ,  A61K47/6835 ,  A61K47/6901

Abstract: Uniform, functional polymer patches can be attached to a fraction of the surface area of living individual cells. These surface-modified cells can cross the blood-brain barrier while remaining viable after attachment of the functional patch. Functional payloads carried by the patch can include a drug. The patch can include one or more polyelectrolyte multilayers (PEMs).

公开(公告)号：US11149154B2

公开(公告)日：2021-10-19

申请号：US15635159

申请日：2017-06-27

Applicant: Massachusetts Institute of Technology ,  Khalifa University of Science and Technology

Inventor： Robert E. Cohen ,  Michael F. Rubner ,  Dayong Chen ,  Roberta Polak ,  Kenan Song ,  Khalid Askar

IPC: C09D7/00 ,  C09D7/40 ,  B05D1/02 ,  C09D163/00 ,  C09D7/20 ,  C09D7/61 ,  B29C70/00 ,  B05D3/06 ,  C08K7/26 ,  C08K3/34 ,  C08K3/36 ,  C08K3/04 ,  B82Y30/00 ,  B82Y40/00

Abstract: A simple spray coating process can be utilized to create epoxy/HNT nanocomposites with vertically aligned nanotubes. Important mechanical properties such as modulus and hardness values can be optimized and enhanced by controlling the level of nanotube dispersion during processing and the final orientation of the nanotubes. Thus, a technologically relevant processing scheme can be used to fabricate HNT nanocomposites with a high level of control over nanotube alignment and the resulting mechanical properties.

公开(公告)号：US20180002550A1

公开(公告)日：2018-01-04

申请号：US15635159

申请日：2017-06-27

Applicant: Massachusetts Institute of Technology

Inventor： Robert E. Cohen ,  Michael F. Rubner ,  Dayong Chen ,  Roberta Polak ,  Kenan Song ,  Khalid Askar

IPC: C09D7/12 ,  C09D7/00 ,  C09D163/00 ,  B05D3/06 ,  B05D1/02 ,  C08K7/26 ,  C08K3/34

CPC classification number: C09D7/70 ,  B05D1/02 ,  B05D3/067 ,  B05D2203/35 ,  B05D2401/10 ,  B05D2504/00 ,  B29C70/00 ,  B82Y30/00 ,  B82Y40/00 ,  C08K3/041 ,  C08K3/042 ,  C08K3/044 ,  C08K3/34 ,  C08K3/346 ,  C08K3/36 ,  C08K7/26 ,  C08K2201/011 ,  C09D7/20 ,  C09D7/61 ,  C09D163/00

Abstract: A simple spray coating process can be utilized to create epoxy/HNT nanocomposites with vertically aligned nanotubes. Important mechanical properties such as modulus and hardness values can be optimized and enhanced by controlling the level of nanotube dispersion during processing and the final orientation of the nanotubes. Thus, a technologically relevant processing scheme can be used to fabricate HNT nanocomposites with a high level of control over nanotube alignment and the resulting mechanical properties.