公开(公告)号：WO0167896A3

公开(公告)日：2002-10-31

申请号：PCT/EP0102939

申请日：2001-03-15

Applicant: BASF AG ,  BETZ ROLAND ,  BEWERT WOLFGANG ,  ERNST ANDREAS ,  KAESLER BRUNO ,  PFEIFFER ANGELIKA-MARIA ,  RUNGE FRANK ,  SCHNEIDER JOACHIM U ,  STANG MICHAEL

Inventor： BETZ ROLAND ,  BEWERT WOLFGANG ,  ERNST ANDREAS ,  KAESLER BRUNO ,  PFEIFFER ANGELIKA-MARIA ,  RUNGE FRANK ,  SCHNEIDER JOACHIM U ,  STANG MICHAEL

IPC: A23K1/00 ,  A23K1/16 ,  A23K1/165 ,  A23K1/17 ,  A23K1/20 ,  A23L1/302 ,  A61K8/04 ,  A61K8/06 ,  A61K8/67 ,  A61K8/92 ,  A61K9/10 ,  A61K31/197 ,  A61K31/375 ,  A61K31/4188 ,  A61K31/4415 ,  A61K31/455 ,  A61K31/51 ,  A61K31/525 ,  A61K31/593 ,  A61K31/714 ,  A61K47/12 ,  A61K47/22 ,  A61P3/02 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q19/00 ,  B02C23/24

CPC classification number: A61K31/525 ,  A23K20/174 ,  A23K40/00 ,  A23K40/30 ,  A23L33/15 ,  A23V2002/00 ,  A61K8/044 ,  A61K8/67 ,  A61K9/10 ,  A61K31/375 ,  A61K31/4415 ,  A61K31/593 ,  A61K31/714 ,  A61K2800/412 ,  A61Q19/00 ,  A61K2300/00 ,  A23V2250/18 ,  A23V2250/211 ,  A23V2250/708 ,  A23V2250/712 ,  A23V2250/7042 ,  A23V2250/7146 ,  A23V2250/702 ,  A23V2250/70 ,  A23V2250/705 ,  A23V2250/1944 ,  A23V2250/704 ,  A23V2250/714 ,  A23V2250/71

Abstract: The invention relates to a method of producing oily suspensions of water-soluble vitamins. The inventive method is characterized by a) grinding at least one water-soluble vitamin in an oil to an average particle size of from 0.1 to 100 mu m, or b) grinding at least one water-soluble vitamin to an average particle size of from 0.1 to 100 mu m without using a continuous phase, and then suspending the ground particles in an oil.

Abstract translation: 本发明涉及一种生产在油米研磨至少一种水溶性维生素的水溶性维生素，其特征在于，为0.1至100微米的平均粒度的油状悬浮液）或b）至少一种水溶性维生素，而无需使用 连续相为0.1〜100微米的研磨，然后悬浮在油研磨颗粒的平均颗粒尺寸。

公开(公告)号：HU185159B

公开(公告)日：1984-12-28

申请号：HU387381

申请日：1981-12-18

Applicant: BASF AG

Inventor： HOPPE PETER P ,  SCHNEIDER JOACHIM U ,  SCHULZ BERNHARD ,  TIEFENBACHER HUBERT

IPC: A61K9/00 ,  A61K9/107 ,  A61K47/14 ,  A61K47/26 ,  A61K47/44 ,  A61K31/015 ,  A61K9/10

Abstract: A process for the preparation of beta -carotene micellar solutions, wherein a non-ionic emulsifier which is suitable for the preparation of micellar solutions is heated at from 160 DEG to 180 DEG C. and a total of from 20 to 30% by weight, based on the emulsifier, of beta -carotene is introduced in the presence of a conventional antioxidant, the hot homogeneous mixture is cooled rapidly to below 100 DEG C. by adding water, and the formulation is brought to the desired concentration of from 3 to 6% by weight by adding further water, and the beta -carotene micellar solutions obtained by this process. The non-ionic emulsifiers used in this process have an HLB value of from 12 to 16, and are in particular oxyethylated triglycerides of fatty acids of 12 to 18 carbon atoms containing 20-60 oxyethylene units. Parenteral admininstration of the stable beta -carotene micellar solutions according to the invention to cattle relieves the disturbed estrus cycle and impaired fertility caused by beta -carotene deficiency.

公开(公告)号：CA1080243A

公开(公告)日：1980-06-24

申请号：CA292829

申请日：1977-12-09

Applicant: BASF AG

Inventor： JAEDICKE HAGEN ,  PAUST JOACHIM ,  SCHNEIDER JOACHIM U

IPC: C09B61/00 ,  C07C20060101 ,  C07C67/00 ,  C07C401/00 ,  C07C403/00 ,  C07C403/24 ,  C07G20060101 ,  C07C175/00

Abstract: A process for the manufacture of canthaxanthin by oxidizing isozeaxanthin or 4'-hydroxyechinenone with a salt of chloric acid or of bromic acid in the presence of a catalyst and of an inert diluent or solvent at from 0 to 100.degree.C. Suitable catalysts are the halogens bromine and iodine.

公开(公告)号：DK1272059T3

公开(公告)日：2006-03-13

申请号：DK01927730

申请日：2001-03-15

Applicant: BASF AG

Inventor： BETZ ROLAND ,  BEWERT WOLFGANG ,  PFEIFFER ANGELIKA-MARIA ,  RUNGE FRANK ,  STANG MICHAEL ,  ERNST ANDREAS ,  KAESLER BRUNO ,  SCHNEIDER JOACHIM U

IPC: A23K1/00 ,  A23K1/16 ,  A23K1/165 ,  A23K1/20 ,  A23K20/195 ,  A23L33/15 ,  A61K8/04 ,  A61K8/06 ,  A61K8/67 ,  A61K8/92 ,  A61K9/10 ,  A61K31/197 ,  A61K31/375 ,  A61K31/4188 ,  A61K31/4415 ,  A61K31/455 ,  A61K31/51 ,  A61K31/525 ,  A61K31/593 ,  A61K31/714 ,  A61K47/12 ,  A61K47/22 ,  A61P3/02 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q19/00 ,  B02C23/24

Abstract: The invention relates to a method of producing oily suspensions of water-soluble vitamins which comprises a) grinding at least one water-soluble vitamin in an oil until the average particle size of from 0.1 to 100 mum, or b) grinding at least one water-soluble vitamin without using a continuous phase until the average particle size of from 0.1 to 100 mum and subsequently suspending the ground particles in an oil.

公开(公告)号：AU5468701A

公开(公告)日：2001-09-24

申请号：AU5468701

申请日：2001-03-15

Applicant: BASF AG

Inventor： BETZ ROLAND ,  BEWERT WOLFGANG ,  ERNST ANDREAS ,  KASLER BRUNO ,  PFEIFFER ANGELIKA-MARIA ,  RUNGE FRANK ,  SCHNEIDER JOACHIM U ,  STANG MICHAEL

IPC: A23K1/00 ,  A23K1/16 ,  A23K1/165 ,  A23K1/20 ,  A23K20/195 ,  A23L33/15 ,  A61K8/04 ,  A61K8/06 ,  A61K8/67 ,  A61K8/92 ,  A61K9/10 ,  A61K31/197 ,  A61K31/375 ,  A61K31/4188 ,  A61K31/4415 ,  A61K31/455 ,  A61K31/51 ,  A61K31/525 ,  A61K31/593 ,  A61K31/714 ,  A61K47/12 ,  A61K47/22 ,  A61P3/02 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q19/00 ,  B02C23/24 ,  A23L1/302

Abstract: The invention relates to a method of producing oily suspensions of water-soluble vitamins which comprises a) grinding at least one water-soluble vitamin in an oil until the average particle size of from 0.1 to 100 mum, or b) grinding at least one water-soluble vitamin without using a continuous phase until the average particle size of from 0.1 to 100 mum and subsequently suspending the ground particles in an oil.

公开(公告)号：CA1185185A

公开(公告)日：1985-04-09

申请号：CA391630

申请日：1981-12-07

Applicant: BASF AG

Inventor： HOPPE PETER P ,  SCHNEIDER JOACHIM U ,  SCHULZ BERNHARD ,  TIEFENBACHER HUBERT

IPC: A61K9/00 ,  A61K9/107 ,  A61K47/14 ,  A61K47/26 ,  A61K47/44 ,  A61K31/23

Abstract: A process for the preparation of .beta.-carotene micellar solutions, wherein a non-ionic emulsifier which is suitable for the preparation of micellar solutions is heated at from 160 to 180.degree.C and a total of from 20 to 30% by weight, based on the emulsifier, of .beta.-carotene is introduced in the presence of a conventional antioxidant, the hot homogeneous mixture is cooled rapidly to below 100.degree.C by adding water, and the formulation is brought to the desired concentration of from 3 to 6% by weight by adding further water, and the .beta.-carotene micellar solutions obtained by this process. The non-ionic emulsifiers used in this process have an HLB value of from 12 to 16, and are in particular oxyethylated triglycerides of fatty acids of 12 to 18 carbon atoms containing 20 - 60 oxyethylene units. Parenteral administration of the stable .beta.-carotene micellar solutions according to the invention to cattle relieves the disturbed estrus cycle and impaired fertility caused by .beta.-carotene deficiency.