公开(公告)号：BRPI0611062A2

公开(公告)日：2011-03-15

申请号：BRPI0611062

申请日：2006-05-30

Applicant: BASF AG

Inventor： KORADIN CHRISTOPHER ,  VON DEYN WOLFGANG ,  RACK MICHAEL ,  ZIERKE THOMAS ,  KUHN DAVID G ,  CULBERTSON DEBORAH L ,  ANSPAUGH DOUGLAS D ,  OLOUMI-SADEGHI HASSAN

IPC: A01N43/653 ,  C07D249/10

Abstract: Compounds of formula (I) wherein X is chloro or bromo; Y is chloro or trifluoromethyl; and A and B are hydrogen or methyl with the proviso that one of A or B must be methyl; or the enantiomers or salts thereof, use of compounds of formula I for combating insects or acarids and for treating, controlling, preventing or protecting animals against infestation or infection by parasites, and compositions comprising compounds of formula I.

公开(公告)号：CA2189691C

公开(公告)日：2011-02-15

申请号：CA2189691

申请日：1995-04-26

Applicant: BASF AG

Inventor： AMBERG WILHELM ,  BERNARD HARALD ,  BUSCHMANN ERNST ,  HAUPT ANDREAS ,  JANITSCHKE LOTHAR ,  JANSSEN BERND ,  KARL ULRICH ,  KLING ANDREAS ,  MULLER STEFAN ,  DE POTZOLLI BERND ,  RITTER KURT ,  THYES MARCO ,  ZIERKE THOMAS

IPC: A61K38/00 ,  C07K5/103 ,  A61P35/00 ,  C07K5/10 ,  C07K7/06

Abstract: Compounds of formula (I) are disclosed, wherein R1, R2, R3, and R4 have the meanings indicated in the description, as well as a process for the production of these compounds. The compounds are suitable for use as starting material for the synthesis of substances which have anti-tumour properties.

公开(公告)号：CA2626503A1

公开(公告)日：2007-05-10

申请号：CA2626503

申请日：2006-10-26

Applicant: BASF AG

Inventor： ZIERKE THOMAS

IPC: A01N37/52 ,  C07C257/22

公开(公告)号：CA2611129A1

公开(公告)日：2006-12-07

申请号：CA2611129

申请日：2006-05-30

Applicant: BASF AG

Inventor： ZIERKE THOMAS ,  KORADIN CHRISTOPHER ,  ANSPAUGH DOUGLAS D ,  OLOUMI-SADEGHI HASSAN ,  VON DEYN WOLFGANG ,  RACK MICHAEL ,  CULBERTSON DEBORAH L ,  KUHN DAVID G

IPC: A01N43/653 ,  C07D249/10

Abstract: Compounds of formula (I) wherein X is chloro or bromo; Y is chloro or trifluoromethyl; and A and B are hydrogen or methyl with the proviso that one of A or B must be methyl; or the enantiomers or salts thereof, use of compounds of formula (I) for combating insects or acarids and for treating, controlling, preventing or protecting animals against infestation or infection by parasites, and compositions comprising compounds of formula (I).

公开(公告)号：ZA200410075B

公开(公告)日：2006-07-26

申请号：ZA200410075

申请日：2004-12-14

Applicant: BASF AG

Inventor： HAMPRECHT GERHARD ,  PUHL MICHAEL ,  REINHARD ROBERT ,  SAGASSER INGO ,  SCHMIDT THOMAS ,  GOETZ NORBERT ,  ZIERKE THOMAS

IPC: C07D239/54 ,  C07C20060101 ,  C07C303/34 ,  C07C303/38 ,  C07C303/40 ,  C07C307/00 ,  C07C307/06 ,  C07C307/08 ,  C07C307/10 ,  C07D207/48 ,  C07D211/96 ,  C07D239/46 ,  C07D295/26

Abstract: The present invention relates to a process for preparing sulfamoyl halides of primary or secondary amines, comprising the following steps: i) reacting a primary or secondary amine A1 with at least equimolar amounts of SO 3 or an SO 3 source in the presence of at least equimolar amounts of a tertiary amine A2, based in each case on the amine A1, and ii) reacting the reaction mixture obtained in step i) with at least the amount of a phosphorus halide required by the stoichiometry; The invention further relates to a process for preparing sulfonic diamides, comprising the preparation of sulfamoyl halides by means of carrying out steps i) and ii) and subsequently reacting the sulfamoyl halide obtained with ammonia. The invention further relates to the use of this process for preparing active herbicidal ingredients having a sulfuric diamide structure. The invention further relates to novel sulfamoyl chlorides.

公开(公告)号：BR0309922A

公开(公告)日：2005-02-15

申请号：BR0309922

申请日：2003-05-15

Applicant: BASF AG

Inventor： HAMPRECHT GERHARD ,  PUHL MICHAEL ,  REINHARD ROBERT ,  SAGASSER INGO ,  SCHMIDT THOMAS ,  GOETZ NORBERT ,  ZIERKE THOMAS

IPC: C07D239/54 ,  C07C303/34 ,  C07C303/38 ,  C07C303/40 ,  C07C307/00 ,  C07C307/06 ,  C07C307/08 ,  C07C307/10 ,  C07D207/48 ,  C07D211/96 ,  C07D239/46 ,  C07D295/26 ,  C07C307/02

Abstract: The present invention relates to a process for preparing sulfamoyl halides of primary or secondary amines, comprising the following steps: i) reacting a primary or secondary amine A1 with at least equimolar amounts of SO 3 or an SO 3 source in the presence of at least equimolar amounts of a tertiary amine A2, based in each case on the amine A1, and ii) reacting the reaction mixture obtained in step i) with at least the amount of a phosphorus halide required by the stoichiometry; The invention further relates to a process for preparing sulfonic diamides, comprising the preparation of sulfamoyl halides by means of carrying out steps i) and ii) and subsequently reacting the sulfamoyl halide obtained with ammonia. The invention further relates to the use of this process for preparing active herbicidal ingredients having a sulfuric diamide structure. The invention further relates to novel sulfamoyl chlorides.

公开(公告)号：SI9520061B

公开(公告)日：2002-02-28

申请号：SI9520061

申请日：1995-04-26

Applicant: BASF AG

Inventor： AMBERG WILHELM ,  BERNARD HARALD ,  BUSCHMANN ERNST ,  HAUPT ANDREAS ,  JANITSCHKE LOTHAR ,  JANSSEN BERND ,  KARL ULRICH ,  KLING ANDREAS ,  MUELLER STEFAN ,  DE POTZOLLI BERND ,  RITTER KURT ,  THYES MARCO ,  ZIERKE THOMAS

IPC: A61K38/08 ,  A61K38/00 ,  A61P35/00 ,  C07K1/08 ,  C07K5/10 ,  C07K5/103 ,  C07K7/06 ,  C07K14/52

Abstract: PCT No. PCT/EP95/01577 Sec. 371 Date Nov. 4, 1996 Sec. 102(e) Date Nov. 4, 1996 PCT Filed Apr. 26, 1995 PCT Pub. No. WO95/30691 PCT Pub. Date Nov. 16, 1995The compound Me2Val-Val-MeVal-Pro-Pro-NHBzlxHCl is described. It is prepared from Z-Val-Val-MeVal-Pro-OR1 where Z and R1 have the meanings stated in the description. The compound shows antineoplastic activity.

公开(公告)号：NO310865B1

公开(公告)日：2001-09-10

申请号：NO991010

申请日：1999-03-02

Applicant: BASF AG

Inventor： SCHAEFER BERND ,  ZIERKE THOMAS

IPC: C07D213/81 ,  C07B43/00 ,  C07C257/10 ,  C07D213/73 ,  C07D213/78 ,  C07D271/06 ,  C07D401/12 ,  C07D413/12 ,  C07K1/06 ,  C07K5/062

Abstract: A process for preparing amidines and their salts with inorganic or organic acids comprises reacting the corresponding nitrile with ammonia, C1-C6-alkylamine or hydrazine in the presence of a mercaptocarboxylic acid and in the presence or absence of an in-organic or organic ammonium salt.

公开(公告)号：CZ2000176A3

公开(公告)日：2001-06-13

申请号：CZ2000176

申请日：1998-07-07

Applicant: BASF AG

Inventor： JANSSEN BERND ,  BARLOZZARI TERESA ,  HAUPT ANDREAS ,  ZIERKE THOMAS ,  KLING ANDREAS

IPC: A61K38/00 ,  A61K38/08 ,  A61P35/00 ,  C07K7/06 ,  C12P19/34

Abstract: Compounds of the present invention include cell growth inhibitors which are peptides of Formula I, A-B-D-E-F-(G)r-(K)s-L  (I), and acid salts thereof, wherein A, B, D, E, F, G and K are α-amino acid residues, and s and r are each, independently, 0 or 1. L is a monovalent radical, such as, for example, an amino group, an N-substituted amino group, a &bgr;-hydroxylamino group, a hydrazido group, an alkoxy group, a thioalkoxy group, an aminoxy group, or an oximato group. The present invention also includes a method for treating cancer in a mammal, such as a human, comprising administering to the mammal an effective amount of a compound of Formula I in a pharmaceutically acceptable composition.

公开(公告)号：PL180652B1

公开(公告)日：2001-03-30

申请号：PL32115995

申请日：1995-04-26

Applicant: BASF AG

Inventor： AMBERG WILHELM ,  BERNARD HARALD ,  BUSCHMANN ERNST ,  HAUPT ANDREAS ,  JANITSCHKE LOTHAR ,  JANSSEN BERND ,  KARL ULRICH ,  KLING ANDREAS ,  MUELLER STEFAN ,  DE POTZOLLI BERND ,  RITTER KURT ,  THYES MARCO ,  ZIERKE THOMAS

IPC: A61K38/08 ,  A61P35/00 ,  C07K1/08 ,  C07K5/10 ,  A61K38/00 ,  C07K5/103 ,  C07K7/06 ,  C07K14/52

Abstract: PCT No. PCT/EP95/01577 Sec. 371 Date Nov. 4, 1996 Sec. 102(e) Date Nov. 4, 1996 PCT Filed Apr. 26, 1995 PCT Pub. No. WO95/30691 PCT Pub. Date Nov. 16, 1995The compound Me2Val-Val-MeVal-Pro-Pro-NHBzlxHCl is described. It is prepared from Z-Val-Val-MeVal-Pro-OR1 where Z and R1 have the meanings stated in the description. The compound shows antineoplastic activity.