公开(公告)号：US20160169742A1

公开(公告)日：2016-06-16

申请号：US14969096

申请日：2015-12-15

Applicant: Korea Research Institute of Standards and Science

Inventor： Yong Jai Cho ,  Won Chegal ,  Hyun Mo Cho

IPC: G01J3/447 ,  G01J4/04

CPC classification number: G01J3/447 ,  G01J4/04 ,  G01N21/211 ,  G01N2021/213

Abstract: Provided are a rotating-element spectroscopic ellipsometer and a method for measurement precision prediction of a rotating-element spectroscopic ellipsometer, a recording medium storing program for executing the same, and a computer program stored in a medium for executing the same, and more particularly, a rotating-element spectroscopic ellipsometer and a method for measurement precision prediction of a rotating-element spectroscopic ellipsometer capable of calculating the measurement precision of the rotating-element spectroscopic ellipsometer based on a theoretical equation on standard deviations of ellipsometric parameters for a sample, a recording medium storing program for executing the same, and a computer program stored in a medium for executing the same.

Abstract translation: 本发明提供了一种旋转元件分光椭偏仪和旋转元件分光椭偏仪的精度预测方法，用于执行旋转元件分光椭偏仪的记录介质存储程序以及存储在其执行介质的计算机程序， 旋转元件分光椭偏仪和用于测量旋转元件分光椭偏仪的精度预测的方法，其能够基于关于样品的椭偏参数的标准偏差的理论等式计算旋转元件分光椭偏仪的测量精度，记录 用于执行该存储程序的介质存储程序和存储在用于执行该程序的介质中的计算机程序。

公开(公告)号：US20160054273A1

公开(公告)日：2016-02-25

申请号：US14754336

申请日：2015-06-29

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： Seok-Won Hyung ,  Byungjoo Kim

IPC: G01N30/14 ,  G01N30/72

CPC classification number: G01N30/463 ,  G01N30/38 ,  G01N30/72

Abstract: Provided is a two-dimensional liquid chromatography system, and more particularly, a two-dimensional liquid chromatography system capable of performing both independent one-dimensional separation through a reversed-phase or normal-phase chromatography method and two-dimensional separation for removing a matrix effect in a single system.

Abstract translation: 本发明提供一种二维液相色谱系统，更具体地说，涉及能够通过反相色谱法或正相色谱法进行独立的一维分离的二维液相色谱系统和用于除去基质的二维分离 效果在一个单一的系统。

公开(公告)号：US20150357103A1

公开(公告)日：2015-12-10

申请号：US14758313

申请日：2013-12-27

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： Young Joo KIM ,  Dong Jin YOON

IPC: H01F5/00

CPC classification number: H01F5/00

Abstract: A coil according to one embodiment of the present invention relates to a coil having a multi-layer structure, comprising n winding wires (n≧2, n is natural number) which are spaced apart from a central axis and wound around the central axis, wherein a first winding of the n windings is wound to a first height in a direction perpendicular to a reference surface, a second winding is wound to a second height lower than the first height in a direction perpendicular to the reference surface, the first winding has a first radius from the central axis, the second winding has a second radius from the central axis, the second radius being smaller than the first radius, and the second winding wire is disposed in the first winding wire.

Abstract translation: 根据本发明的一个实施例的线圈涉及一种具有多层结构的线圈，包括与中心轴线间隔开并缠绕在中心轴线上的n根绕组线（n≥2，n是自然数） 其中所述n个绕组的第一绕组在垂直于参考表面的方向上缠绕到第一高度，第二绕组在垂直于所述参考表面的方向上缠绕到比所述第一高度低的第二高度，所述第一绕组具有 所述第二绕组具有从所述中心轴线的第一半径，所述第二绕组具有距所述中心轴线的第二半径，所述第二半径小于所述第一半径，所述第二绕组线设置在所述第一绕组线中。

公开(公告)号：US20150226813A1

公开(公告)日：2015-08-13

申请号：US14692294

申请日：2015-04-21

Applicant: Korea Research Institute of Standards and Science

Inventor： Kwon-Kyu Yu ,  Yong-Ho Lee ,  Hyukchan Kwon ,  Jin-Mok Kim ,  Kiwoong Kim ,  Sang-Kil Lee

IPC: G01R33/035 ,  G01R33/00

CPC classification number: G01R33/0354 ,  A61B5/04005 ,  A61B5/05 ,  G01R33/0047 ,  G01R33/0082 ,  H05K7/02

Abstract: Provided are a low-temperature cooling apparatus and a superconducting quantum interference device (SQUID) sensor module. The low-temperature cooling apparatus includes an outer container; an inner container disposed inside the outer container, the inner container including a neck portion having a first diameter and a body portion having a second diameter greater than the first diameter; an insert inserted into the neck portion of the inner container; and a plurality of SQUID sensor modules inserted into the body portion of the inner container. Each of the SQUID sensor modules is in the form of a fan-shaped pillar and is fixedly coupled with an inner bottom plate of the inner container.

Abstract translation: 提供低温冷却装置和超导量子干涉装置（SQUID）传感器模块。 低温冷却装置包括外容器; 内部容器，其设置在所述外部容器的内部，所述内部容器包括具有第一直径的颈部部分和具有大于所述第一直径的第二直径的主体部分; 插入到所述内部容器的颈部中的插入件; 以及插入到所述内部容器的主体部分中的多个SQUID传感器模块。 每个SQUID传感器模块都是扇形柱的形式，并与内部容器的内底板固定连接。

公开(公告)号：US20140302545A1

公开(公告)日：2014-10-09

申请号：US14345835

申请日：2012-09-18

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： Duk Jin Kang ,  Sang Ryoul Park ,  Sook-Kyung Kim

IPC: C12Q1/37

CPC classification number: C12Q1/37 ,  C07K1/20 ,  C07K1/34 ,  C07K1/36 ,  C12M21/18 ,  C12M25/12 ,  C12P21/06

Abstract: Provided are an enzyme treatment apparatus for proteins using a hollow fiber membrane and an on-line proteomics method using same. The enzyme treatment apparatus for proteins according to the present invention can increase a recovery rate of peptides, which are recovered through an enzyme treatment process, by basically solving the problem of low reproducibility of an enzyme activity which may occur during a conventional enzyme treatment process, and can also reduce a time for purification and provide higher yield by performing separation and purification through a single step. In particular, the present invention can be usefully applied for developing a disease-specific protein biomarker through a statistical analysis method having highly efficient detectability for proteins in research for finding biomarkers related to human diseases.

Abstract translation: 提供了使用中空纤维膜的蛋白质的酶处理装置和使用其的在线蛋白质组学方法。 根据本发明的蛋白质的酶处理装置可以通过基本上解决在常规酶处理过程中可能发生的酶活性的低再现性的问题来提高通过酶处理过程回收的肽的回收率， 并且还可以通过单步执行分离和纯化来减少纯化时间并提供更高的产率。 特别地，本发明可以有用地用于通过统计分析方法开发疾病特异性蛋白质生物标志物，所述统计分析方法在用于寻找与人类疾病相关的生物标志物的研究中具有高度可检测性的蛋白质。

公开(公告)号：US20140235996A1

公开(公告)日：2014-08-21

申请号：US14260750

申请日：2014-04-24

Applicant: Korea Research Institute of Standards and Science

Inventor： Kiwoong Kim ,  Hyukchan Kwon ,  Yong-Ho Lee ,  Kwon-Kyu Yu ,  Jin-Mok Kim

IPC: A61B5/04 ,  A61B6/03 ,  A61B5/055

CPC classification number: A61B5/04011 ,  A61B5/04007 ,  A61B5/04012 ,  A61B5/0402 ,  A61B5/0522 ,  A61B5/055 ,  A61B6/03 ,  G16H50/50

Abstract: A method for mapping of myocardial electric activity includes measuring electrocardiogram data or magnetocardiogram data and mapping the degree of electric activity of a myocardial surface using the electrocardiogram data or the magnetocardiogram data. A signal source of the electrocardiogram data or the magnetocardiogram data is a myocardial surface potential that is scalar quantity. The mapping uses a lead-field vector which represents the sensitivity between the myocardial surface potential and the electrocardiogram or magnetocardiogram data, and a modified lead-field vector which combines a constraint matrix with a constraint condition where no potential sources exist in a specific region.

Abstract translation: 用于映射心肌电活动的方法包括使用心电图数据或心电图数据测量心电图数据或磁心图数据并映射心肌表面的电活动程度。 心电图数据或心电图数据的信号源是标量量的心肌表面电位。 映射使用表示心肌表面电位和心电图或磁心图数据之间的灵敏度的引导场向量，以及将约束矩阵与在特定区域中不存在潜在源的约束条件组合的修改的引线域向量。

公开(公告)号：US08742336B2

公开(公告)日：2014-06-03

申请号：US13727018

申请日：2012-12-26

Applicant: Korea Research Institute of Standards and Science

Inventor： Young-Pil Kim ,  Tae Geol Lee

IPC: H01J49/04

CPC classification number: H01J49/0409 ,  B82Y15/00 ,  G01N1/00 ,  H01J49/00 ,  H01J49/26 ,  Y10S977/902

Abstract: There are provided a bio-chip for secondary ion mass spectrometry and a method of fabricating the same, the bio-chip, which is a bio-chip for analyzing a biochemical material using the secondary ion mass spectrometry, including: a substrate; and core-shell particles positioned above substrate, wherein the core-shell particles each include a metal nanoparticle as a core and a metal shell surrounding the metal nanoparticle.

Abstract translation: 提供了二次离子质谱法的生物芯片及其制造方法，该生物芯片是使用二次离子质谱法分析生化材料的生物芯片，其包括：底物; 以及位于基材上方的核 - 壳颗粒，其中核 - 壳颗粒各自包括作为芯的金属纳米颗粒和围绕金属纳米颗粒的金属壳。

公开(公告)号：US20130292561A1

公开(公告)日：2013-11-07

申请号：US13727018

申请日：2012-12-26

Applicant: Korea Research Institute of Standards and Science

Inventor： Young-Pil KIM ,  Tae Geol LEE

IPC: G01N1/00 ,  H01J49/26

CPC classification number: H01J49/0409 ,  B82Y15/00 ,  G01N1/00 ,  H01J49/00 ,  H01J49/26 ,  Y10S977/902

Abstract: There are provided a bio-chip for secondary ion mass spectrometry and a method of fabricating the same, the bio-chip, which is a bio-chip for analyzing a biochemical material using the secondary ion mass spectrometry, including: a substrate; and core-shell particles positioned above substrate, wherein the core-shell particles each include a metal nanoparticle as a core and a metal shell surrounding the metal nanoparticle.

Abstract translation: 提供了二次离子质谱法的生物芯片及其制造方法，该生物芯片是使用二次离子质谱法分析生化材料的生物芯片，其包括：底物; 以及位于基材上方的核 - 壳颗粒，其中核 - 壳颗粒各自包括作为芯的金属纳米颗粒和围绕金属纳米颗粒的金属壳。

公开(公告)号：US12270762B2

公开(公告)日：2025-04-08

申请号：US16982850

申请日：2019-09-18

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： Eun-Ah You ,  Wansun Kim ,  Tae Geol Lee

IPC: G01N21/65 ,  B82B1/00 ,  B82Y30/00 ,  B82Y40/00 ,  G01N33/483 ,  G01N33/553

Abstract: Provided is a Raman-active particle which is a Raman-active particle for surface-enhanced Raman analysis, the particle including: a spherical plasmonic metal core; a plasmonic metal shell having surface unevenness; and a self-assembled monolayer which is bonded to each of the core and the shell and positioned between the core and the shell, and includes a Raman reporter.

公开(公告)号：US20240353459A1

公开(公告)日：2024-10-24

申请号：US18684882

申请日：2021-12-21

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： In Ho BAE ,  Seon Do LIM ,  No Weon KANG

IPC: G01R29/08 ,  G01R29/12

CPC classification number: G01R29/0885 ,  G01R29/12

Abstract: The present disclosure relates to an electromagnetically induced grating-based electric field detection system and method and, more particularly, to an electric field detection system and method which enable the creation of an electromagnetically induced transparency grating using a low-wavelength laser and enables real-time electromagnetic wave measurement by avoiding the frequency reprocessing of the signal that is essential in the existing Rydberg atom-based electric field measurement technology.
An electromagnetically induced grating-based electric field detection system according to an embodiment of the present disclosure may include a vapor cell; an irradiation light source which irradiates irradiation light to be incident on one end of the vapor cell; a combined light source which irradiates combined light to be incident on another end of the vapor cell; a reflector which reflects the combined light that has passed through the vapor cell and makes it incident on the one end of the vapor cell; an electromagnetic wave generator which generates an electromagnetic wave to be incident on one side surface of the vapor cell; and a reflected light detector which detects a reflected light released from the vapor cell.
According to one embodiment of the present disclosure, in the Rydberg atom-based electric field measurement technology, there is an advantage in that real-time electric field measurement is possible without signal frequency reprocessing.