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公开(公告)号:CA2305499A1
公开(公告)日:1999-04-22
申请号:CA2305499
申请日:1998-09-18
Applicant: BASF AG
Inventor: ERHARDT MELANIE , PUHL MICHAEL , KOHL TANJA , HERGENRODER STEFAN , HILLEN HEINZ , ZECHEL JOHANN-CHRISTIAN , MARKERT CLAUS OTTO , DITRICH KLAUS
IPC: C07D333/40 , A61K31/198 , A61K31/27 , A61K31/381 , A61K31/4704 , A61K31/498 , A61P1/04 , A61P1/18 , A61P7/02 , A61P9/04 , A61P9/10 , A61P9/12 , A61P13/08 , A61P13/12 , A61P25/06 , A61P35/00 , C07C271/12 , C07C271/20 , C07C323/56 , C07D215/48 , C07D241/44 , C07D333/38 , C07D333/16 , C07D215/14 , C07C271/22 , A61K31/38 , C07D241/42 , A61K31/47 , A61K31/495
Abstract: Novel pharmaceutically active compounds of general formula (I), their preparation and use for producing pharmaceutical compositions for the treatment of diseases are disclosed. (Endothelin conversion enzyme inhibitors (=ECE)).
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公开(公告)号:MX9605679A
公开(公告)日:1998-02-28
申请号:MX9605679
申请日:1995-05-10
Applicant: BASF AG
Inventor: BUSSCHE-HUNNEFELD CHRISTOPH-SW , KLINTZ RALF , HAMPRECHT GERHARD , HEISTRACHER ELISABETH , SCHAFER PETER , MUNSTER PETER , DITRICH KLAUS , KONIG HARTMANN , WESTPHALEN KARL-OTTO
IPC: A01N43/50 , C07D401/12 , C07D403/12 , C07D405/10 , C07D405/12 , C07D409/10 , C07D413/12
Abstract: Se emplean como herbicidas 3-fenilpirazoides sustituidos de la formula (I) en donde R1 = H, CN, NO2, halogeno, alquilo, alquenilo, alquinilo, haloalquilo, haloalquenilo, haloalquinilo, cianoaqluilo, alqui-O-R6, alquil-O-CO-R6, alquenil-O-R6, alquinil-O-R6, alquil-S-R6, alquenil-S-R6, alquinil-S-R6, alquil-SO-R6, alquenil-SO-R6, alquinil-SO-R6, alquil-SO2-R6, alquenil-SO2-R6 alquinil-SO2-R6, -O-R6, -SO-R6, -SO2-R6, -SO2-C1, SO2-O-R6, -SO2-N(R7, R8), -N(R7, R8), -NH-CO-O-R6, -O-CONH-R7, -NH-CO-NH-R13, -O-CS-N(alquilo C1-C4)2, -OCS-NHS2, -A-CO-O-R6, A-P(O)(OR6)2M -O-(alquilo C1-C4)-CO-OR6, -(alquilo)-O-(alquilo)-C(H/alquilo/fenilo/bencilo) =n-O-alquilo, isoxasolidinilcarbonilo, etc.; R2 = CN, CF3, halogeno; R3 = H, alquilo C1-C4, haloalquilo C1-C4; R4 = alquilo C1-C4, haloalquilo C1-C4; R5 = H, NO2, halogeno, -COOR29, aminocarbonilo sustituido o no sustituido; Z = -O- -S-, -SO-, SO2-; R6, R29 = H alquilo C1-C6; hlaoalquilo C1-C8, alquenilo C3-C6, cicloalquilo C3-C7 sustituido o no sustituido o cicloalquenilo C5-C7, haloalquenilo C3-C6, cianoalquilo C1-C8, alquinilo C3-C6, alcoxi C1-C4-alquilo C1-C4, 3-tetrahidrofuril-alquilo C1-C8, 3-oxetanilo, ??-tietanilo, carboxialquilo C1-C6, alcoxicarbonilo C1-C8-alquilo C1-C6, alcoxi C1-C4-alcoxicarbonilo C1-C4-alquilo C1-C6, cilcopropilmetilo, (1-metiltiociclopropil)metilo, (alfa-alquilalquilden)iminooxy C1-C9-alquilo, C1-C6, alquilcarbonilo C1-C4, alcoxi-, haloalcoxi-, alqueniloxi-, haloalqueniloxi-, o bien arilalcoxiiminoalquilo, fenilo sustituido o no sustituido, fenilalquilo C1-C6, fenilalquenilo C2-C6, fenilalquinilo C3-C6, fenoxialquilo C1-C6, heteroarilo, heteroarilalquilo C1-C6, heteroarilalquenilo C3-C6, heteroarilalquinilo C3-C6, o bien heteroariloxialquinilo C1-C6; R7, R8, R13 = H, alquilo C1-C8, haloalquilo C1-C8, alquenilo C2-C8, alquinilo C2-C8, alcoxi C1-C4-alquilo C1-C4, alquiltio C1-C4-alquilo C1-C4, cianoalquilo C1-C8, carboxialquilo C1-C4, alcoxicarbonilo C1-C4 alquilo C1-C4, alquilsulfonilo C1-C4-alquilo C1-C4, cicloalquilo C3-C8, alcoxi C1-C6, cicloalcoxicarbonilo C3-C6-alquilo C1-C4, alcoxi C1-C4-alcoxicarbonilo C1-C4-alquilo C1-C4, alquilcarbonilo C1-C4, haloalquilcarbonilo C1-C4, tetrahidrofuran-2-onil, fenilo sustituido o no sustituido, fenilalquilo C1-C4, heteroarilo o heteroarilalquilo C1-C4; o bien R6 y R8 son juntos una cadena de etilenoxietileno, pentametileno o tetrametileno sustituido o no sustituido, y las sales de I que pueden emplearse en la agricultura.
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公开(公告)号:HUT76943A
公开(公告)日:1998-01-28
申请号:HU9603320
申请日:1995-05-31
Applicant: BASF AG
Inventor: DITRICH KLAUS , GERBER MATTHIAS , HAMPRECHT GERHARD , HEISTRACHER ELISABETH , KLINTZ RALF , SCHAEFER PETER , WALTER HELMUT , WESTPHALEN KARL-OTTO , VON DEM BUSSCHE-HUENNEFELD CHR
IPC: C07D231/18 , A01N43/56 , A01N47/12 , A01N47/34 , A01N47/40 , C07D231/20 , C07D231/22 , C07D401/06 , C07D401/10 , C07D403/06 , C07D403/10 , C07D405/06 , C07D405/10 , C07D409/06 , A01N43/50
Abstract: PCT No. PCT/EP95/02062 Sec. 371 Date Nov. 26, 1996 Sec. 102(e) Date Nov. 26, 1996 PCT Filed May 31, 1995 PCT Pub. No. WO95/33728 PCT Pub. Date Dec. 14, 1995Substituted 3-phenylpyrazoles I I are used as herbicides.
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公开(公告)号:BR9507913A
公开(公告)日:1997-08-12
申请号:BR9507913
申请日:1995-05-31
Applicant: BASF AG
Inventor: BUSSCHE-HUENNEFELD CHRISTOPH-S , KLINTZ RALF , HAMPRECHT GERHARD , HEISTRACHER ELISABETH , SCHAEFER PETER , DITRICH KLAUS , WESTPHALEN KARL-OTTO , GERBER MATTHIAS , WALTER HELMUT
IPC: C07D231/18 , A01N43/56 , A01N47/12 , A01N47/34 , A01N47/40 , C07D231/20 , C07D231/22 , C07D401/06 , C07D401/10 , C07D403/06 , C07D403/10 , C07D405/06 , C07D405/10 , C07D409/06 , A01N43/50
Abstract: PCT No. PCT/EP95/02062 Sec. 371 Date Nov. 26, 1996 Sec. 102(e) Date Nov. 26, 1996 PCT Filed May 31, 1995 PCT Pub. No. WO95/33728 PCT Pub. Date Dec. 14, 1995Substituted 3-phenylpyrazoles I I are used as herbicides.
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公开(公告)号:CA2229312A1
公开(公告)日:1997-03-20
申请号:CA2229312
申请日:1996-09-09
Applicant: BASF AG
Inventor: DITRICH KLAUS , BALKENHOHL FRIEDHELM , LADNER WOLFGANG
IPC: C12M1/40 , B01J23/04 , C07B53/00 , C07B61/00 , C07C69/708 , C07C209/62 , C07C211/27 , C12P41/00 , C12P13/00 , C07C51/06 , C07C59/125
Abstract: The invention concerns a method of separating optically active amides to form carboxylic acids and optically active amines such thatsthe centre of chirality is maintained. The method is characterized in that the amides are hydrolyzed in the presence of a polyol or an aminoalcohol and an alkali or alkaline earth hydroxide.
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公开(公告)号:CA1331384C
公开(公告)日:1994-08-09
申请号:CA610152
申请日:1989-09-01
Applicant: BASF AG
Inventor: DITRICH KLAUS , HAMPRECHT GERHARD , WUERZER BRUNO , MEYER NORBERT , WESTPHALEN KARL-OTTO , LAATSCH HARTMUT
IPC: A01N43/56 , C07D231/54 , C07D401/04 , C07D403/04 , C07D491/04 , C07D491/056
Abstract: Naphthindazole-4,9-quinones of the formula (I), where: R1 is C2-C10-alkyl, C3-C10-alkenyl, C2-C10-alkynyl, C1-C10-halo- alkyl, C1-C10-hydroxyalkyl, C2-C14-alkoxyalkyl, C2-C14-alkyl-thioalkyl, C3-C7-cycloalkyl, C1-C4-alkylcarbonyloxy-C1-C4-alkyl, C1-C4-alkylaminocarbonyloxy-C1-C4-alkyl, phenylaminocarbonyloxyC1-C4-alkyl which is unsubstituted or substituted in the phenyl moiety by halogen, C1-C4-alkyl or C1-C4-alkoxy, phenylsulfonyloxy-C1-C4-alkyl which is unsubstituted or substituted in the phenyl moiety by halogen, C1-C4-alkyl or C1-C4-alkoxy, C1-C4-alkoxycarbonyl-C1-C4-alkyl, hydroxycarbonyl-C1-C4-alkyl, aminocarbonyl-C1-C4-alkyl, C1-C4-alkylaminocarbonyl-C1-C4-alkyl, di-(C1-C4-alkyl)-aminocarbonyl-C1-C4-alkyl, halo-C3-C4-alkynyl, unsubstituted or halogen- or C1-C4-alkyl-substituted heteroaryl radical with one or two nitrogen atoms, selected from the group consisting of pyrimidyl, pyridyl and imidazolyl, phenyl which is unsubstituted or substituted by halogen, hydroxy, nitro, amino, C1-C4-alkylamino, di-C1-C4-alkylamino, cyano, C1-C4-alkyl, C1-C4-alkoxy, C1-C4-haloalkoxy, C1-C4-haloalkyl, C1-C4-alkylthio or C1-C4-haloalkylthio, or unsubstituted or halogen-substituted benzyl, and R2, R3, R4 and R5 are identical or different and each denotes hydrogen, halogen, nitro, cyano, hydroxy, amino, C1-C4-alkyl-amino, di-C1-C4-alkylamino, C1-C6-alkyl, C1-C5-haloalkyl, C1-C5-alkoxy, C1-C5-haloalkoxy, C1-C5-alkylthio, C1-C5-haloalkyl-thio, C2-C10-alkoxyalkyl, carboxyl, C2-C6-alkoxycarbonyl, C2-C6-alkanoyloxy, C2-C6-haloalkanoyloxy, C1-C4-alkylcarbonylamino, C1-C4-alkylaminocarbonyl, di-(C1-C4-alkyl)-aminocarbonyl, or phenyl or heteroaryl, selected from the group consisting of pyridyl, thienyl, furyl, benzimidazol-1-yl and pyrimid-2-yl, each of which phenyl or heteroaryl group is unsubstituted or substituted by halogen, trifluoromethyl, nitro, cyano, amino, C1-C4-alkoxy, C1-C4-alkylthio or C1-C5-haloalkylthio, and in addition R3 and R4, together with the two carbon atoms of the phenyl ring to which they are attached, form a heterocyclic ring selected from the group consisting of 1,4-dioxane, 1,3-dioxolane, pyrazole, indole, triophene, triazole and piperazine or a benzene or naphthalene ring which is unsubstituted or substituted by halogen, nitro, cyano, amino, hydroxy, trifluoromethyl, C1-C5-alkyl, C1-C5-alkoxy, C1-C5-haloalkylthio, C1-C5-haloalkoxy or C1-C5-alkylthio and their use for combating unwanted plant growth.
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公开(公告)号:HUT58187A
公开(公告)日:1992-02-28
申请号:HU208491
申请日:1991-06-21
Applicant: BASF AG
Inventor: MAYWALD VOLKER , DITRICH KLAUS , KUEKENHOEHNER THOMAS , HAMPRECHT GERHARD , FREUND WOLFGANG , WESTPHALEN KARL-OTTO , GERBER MATTHIAS , WALTER HELMUT
IPC: A01N43/76 , A01N43/78 , A01N43/80 , A01N43/90 , C07D498/04 , C07D499/04 , C07D513/04 , A01N43/74 , C07D263/34 , C07D277/30
Abstract: Dicarboxylic acid imides of the formulae Ia, Ib and Ic … … in which the substituents have the following meaning:… X is oxygen or sulphur;… R is hydrogen; halogen; cyano; alkyl; cycloalkyl; alkenyl; alkynyl; alkoxy; alkenyloxy; alkynyloxy; alkylthio; halogenoalkoxy; halogenoalkylthio; alkylsulphonyl; halogenoalkylsulphonyl; phenyl; phenylalkyl; phenoxy or phenylthio, a 5- to 6-membered saturated or aromatic heterocyclic radical containing one or two hetero atoms selected from the group comprising oxygen, sulphur and nitrogen; it being possible for the said organic radicals to be further substituted;… R is hydrogen; hydroxyl; alkoxy; alkyl; cycloalkyl; alkenyl; alkynyl; di-C1-C4-alkylamino; a 5- to 6-membered heterocyclic saturated or aromatic radical with one or two hetero atoms selected from the group comprising oxygen, sulphur or nitrogen; phenyl; naphthyl; it being possible for the said organic radicals to be further substituted,… and plant-compatible salts of the dicarboxylic acid imides I excepting 3-methylisoxazole-4,5-dicarboximide and thiazole-4,5-dicarboximides in which R is phenyl when R is methyl or 2-thiazolyl, and herbicidal compositions containing these compounds.
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138.
公开(公告)号:HU204830B
公开(公告)日:1992-02-28
申请号:HU309690
申请日:1990-05-18
Applicant: BASF AG
Inventor: FISCHER KLAUS , MAYER HORST , DITRICH KLAUS , HAMPRECHT GERHARD , WESTPHALEN KARL-OTTO , WUERZER BRUNO
IPC: A01N43/90 , C07D471/04 , C07D473/00 , C07D473/06 , C07D473/40 , C07D473/02 , C07D473/26
Abstract: Sulphonamides of the general formula I in which the substituents and indices have the following meanings: R represents hydrogen or C1-C4-alkyl, R represents hydrogen, optionally substituted C1-C6-alkyl; C3-C4-alkenyl; C3-C4-alkynyl or optionally substituted saturated or monounsaturated 5- to 7-membered heteroaryl; R and R represent halogen; optionally substituted C1-C4-alkoxy, C1-C4- alkylthio, C2-C6-alkenyl, C2-C6-alkenyloxy, C2-C6-alkenylthio, C2-C6- alkynyl, C2-C6-alkynyloxy, C2-C6-alkynylthio, C3-C6-cycloalkyl, C3-C6- cycloalkylthio, C5-C6-cycloalkenyl, C3-C6-cycloalkoxy, C5-C6- cycloalkenyloxy, C5-C6-cycloalkenylthio, phenyl, phenoxy, phenylthio, benzyl, benzyloxy or benzylthio; the groups mentioned under R or NR R in which R and R represent hydrogen, C1-C6-alkyl, C3-C6-alkenyl, C3-C6-alkynyl, C3-C6-cycloalkyl, C5-C6-cycloalkenyl, optionally substituted phenyl and/or benzyl, or represent optionally substituted C4-C6-alkylene which can be interrupted by oxygen, sulphur or nitrogen; X represents nitrogen or =CR - in which R represents one of the radicals R , n represents 0 or 1 and A represents optionally substituted aryl with one or two rings, containing one to two nitrogen, oxygen and/or sulphur atom(s), and their agriculturally useful salts, and herbicidal and plant- growth-regulating compositions containing them.
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公开(公告)号:HUT55957A
公开(公告)日:1991-07-29
申请号:HU601290
申请日:1990-09-21
Applicant: BASF AG
Inventor: MAYWALD VOLKER , DITRICH KLAUS , HAMPRECHT GERHARD , HARREUS ALBRECHT , WUERZER BRUNO , WESTPHALEN KARL-OTTO
IPC: A01N43/56 , C07D231/14 , C07D401/02 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/02 , C07D405/04 , C07D405/12 , C07D405/14 , C07D409/02 , C07D409/04 , C07D409/12 , C07D409/14 , C07D413/04 , C07D417/12 , C07D417/14 , C07D417/04
Abstract: Pyrazole-3-carboxamides of the general formula I in which the substituents have the following meanings: R represents hydrogen or optionally substituted C3-C8-cycloalkyl or C1-C4-alkyl, R represents hydroxyl; amino; C1-C4-alkylamino; di-C1-C4-alkylamino, aminocarbonyl-C1-C6-alkyl, optionally substituted C1-C4-alkoxy, C3-C6-alkenyl, C3-C6-alkynyl, phenyl or naphthyl, optionally substituted 5- to 6-membered heterocycle; one of the groups mentioned under R or R and R together form a 4- to 7-membered chain which can contain as ring member one of the following groups in addition to methylene groups: oxygen, sulphur, N-methyl or carbonyl; R represents optionally substituted 5- to 6-membered heterocycle, optionally substituted C3-C6-alkenyl, C3-C6-alkynyl, 5,6,7,8-tetrahydronaphthyl or phenyl, or one of the groups mentioned under R ; R represents nitro; cyano; carboxyl; halogen; optionally substituted C1-C4-alkoxy or C1-C4-alkylthio, or one of the groups mentioned under R ; R represents 4,5-dihydrooxazol-2-yl or a group COYR ; Y represents oxygen or sulphur; R represents hydrogen; C3-C8-cycloalkyl, optionally substituted C1-C6-alkyl, C3-C6-alkenyl, C3-C6-alkynyl, C5-C7-cycloalkenyl or phenyl, optionally substituted 5- to 6-membered heterocycle; phthalimido; tetrahydrophthalimido; succinimido; maleimido; benzotriazolyl or a group -N=CR R where R is hydrogen or C1-C6-alkyl and R is C3-C6-cycloalkyl, phenyl, furyl or a radical R , or R and R together form a 4- to 7-membered alkylene chain, and their agriculturally useful salts, where Y is not oxygen and R is not hydrogen when R is hydrogen and R is nitro, trifluoromethyl, halogen or C1-C4-alkoxy, and -YR is not ethoxy when R is hydrogen, R is methyl and R is phenyl or substituted phenyl.
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公开(公告)号:HU906012D0
公开(公告)日:1991-03-28
申请号:HU601290
申请日:1990-09-21
Applicant: BASF AG
Inventor: MAYWALD VOLKER , DITRICH KLAUS , HAMPRECHT GERHARD , HARREUS ALBRECHT , WUERZER BRUNO , WESTPHALEN KARL-OTTO
IPC: A01N43/56 , C07D231/14 , C07D401/02 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/02 , C07D405/04 , C07D405/12 , C07D405/14 , C07D409/02 , C07D409/04 , C07D409/12 , C07D409/14 , C07D413/04 , C07D417/12 , C07D417/14
Abstract: Pyrazole-3-carboxamides of the general formula I in which the substituents have the following meanings: R represents hydrogen or optionally substituted C3-C8-cycloalkyl or C1-C4-alkyl, R represents hydroxyl; amino; C1-C4-alkylamino; di-C1-C4-alkylamino, aminocarbonyl-C1-C6-alkyl, optionally substituted C1-C4-alkoxy, C3-C6-alkenyl, C3-C6-alkynyl, phenyl or naphthyl, optionally substituted 5- to 6-membered heterocycle; one of the groups mentioned under R or R and R together form a 4- to 7-membered chain which can contain as ring member one of the following groups in addition to methylene groups: oxygen, sulphur, N-methyl or carbonyl; R represents optionally substituted 5- to 6-membered heterocycle, optionally substituted C3-C6-alkenyl, C3-C6-alkynyl, 5,6,7,8-tetrahydronaphthyl or phenyl, or one of the groups mentioned under R ; R represents nitro; cyano; carboxyl; halogen; optionally substituted C1-C4-alkoxy or C1-C4-alkylthio, or one of the groups mentioned under R ; R represents 4,5-dihydrooxazol-2-yl or a group COYR ; Y represents oxygen or sulphur; R represents hydrogen; C3-C8-cycloalkyl, optionally substituted C1-C6-alkyl, C3-C6-alkenyl, C3-C6-alkynyl, C5-C7-cycloalkenyl or phenyl, optionally substituted 5- to 6-membered heterocycle; phthalimido; tetrahydrophthalimido; succinimido; maleimido; benzotriazolyl or a group -N=CR R where R is hydrogen or C1-C6-alkyl and R is C3-C6-cycloalkyl, phenyl, furyl or a radical R , or R and R together form a 4- to 7-membered alkylene chain, and their agriculturally useful salts, where Y is not oxygen and R is not hydrogen when R is hydrogen and R is nitro, trifluoromethyl, halogen or C1-C4-alkoxy, and -YR is not ethoxy when R is hydrogen, R is methyl and R is phenyl or substituted phenyl.
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