公开(公告)号：EP2257818A4

公开(公告)日：2014-01-29

申请号：EP09724323

申请日：2009-03-27

Applicant: HARVARD COLLEGE

Inventor： RECHES MEITAL ,  DICKEY MICHAEL D ,  BUTTE MANISH J ,  WHITESIDES GEORGE M

IPC: G01N35/00 ,  B01L3/00 ,  G01N33/49 ,  G01N33/493 ,  G01N33/50 ,  G01N33/52 ,  G01N33/543

CPC classification number: B01L3/5023 ,  B01L3/5088 ,  B01L2200/0605 ,  B01L2200/10 ,  B01L2300/0825 ,  B01L2300/0845 ,  B01L2300/087 ,  B01L2300/12 ,  B01L2300/161 ,  B01L2400/0406 ,  G01N33/54386

Abstract: Hydrophilic threads as platforms for inexpensive, low volume, portable diagnostic systems, and methods of making the same are described. A diagnostic system includes a hydrophilic loading thread having an inlet zone at a proximal end; a testing zone at a distal end; and an intermediate zone located between the inlet zone and the testing zone, wherein the testing zone does not directly contact the inlet zone. In another aspect, a diagnostic system includes (i) a hydrophilic loading thread that includes an inlet zone at a proximal end and an intermediate zone at a distal end; and (ii) one or more additional hydrophilic threads that contact the intermediate zone of the loading thread. A method of detecting the presence or absence of an analyte in a fluid sample includes applying the sample to an inlet zone of a diagnostic system that includes a hydrophilic loading thread with an inlet zone at a proximal end; an intermediate zone; and a testing zone at a distal end; wherein the testing zone does not directly contact the inlet zone.

公开(公告)号：EP3245028A4

公开(公告)日：2018-06-13

申请号：EP16780397

申请日：2016-01-12

Applicant: HARVARD COLLEGE

Inventor： LESSING JOSHUA AARON ,  WHITESIDES GEORGE M ,  SHEVCHENKO YANINA ,  MOSADEGH BOBAK ,  GALLOWAY KEVIN C ,  TAYI ALOK SURYAVAMSEE

IPC: B25J19/02 ,  B25J9/14 ,  B25J13/08 ,  G01L1/24

CPC classification number: G01T7/00 ,  A61F2002/7615 ,  B25J9/142 ,  B25J13/08 ,  G01L1/246

Abstract: A soft robotic device with a variety of sensors and/or imaging areas is described. The sensor and/or imaging area may be embedded in the soft body or the strain limiting layer of the soft robotic device, attached to the soft body or the strain limiting layer of the soft robotic device, or otherwise linked to the soft body or the strain limiting layer of the soft robotic device.

公开(公告)号：EP3183461A4

公开(公告)日：2018-06-13

申请号：EP15834002

申请日：2015-08-21

Applicant: HARVARD COLLEGE

Inventor： LESSING JOSHUA AARON ,  MARTINEZ RAMSES V ,  TAYI ALOK SURYAVAMSEE ,  TING JASON MING ,  WHITESIDES GEORGE M

IPC: F15B15/10 ,  B25J18/06

CPC classification number: B25J9/142 ,  B25J9/0012 ,  B25J13/08 ,  B25J15/0009 ,  B25J15/12 ,  B25J18/06 ,  B25J19/028 ,  Y10S901/22

Abstract: A soft robot having an integrated electrical component includes an expandable or collapsible body, the body comprising an inlet that is configured to communicate with a fluid source and a flexible strain limited layer secured to a portion of the expandable or collapsible body, wherein the strain limited layer includes at least one electrical component.

公开(公告)号：EP2964427A4

公开(公告)日：2018-02-28

申请号：EP14759711

申请日：2014-03-04

Applicant: HARVARD COLLEGE

Inventor： KWOK SEN W ,  MORIN STEPHEN A ,  MOSADEGH BOBAK ,  SO JU-HEE ,  SHEPHERD ROBERT F ,  WHITESIDES GEORGE M

IPC: B25J9/08 ,  B23P19/04 ,  B25J9/14

CPC classification number: B25J9/14 ,  A63H3/46 ,  B23P19/04 ,  B25J9/08 ,  B25J9/142 ,  B25J15/0023 ,  B25J15/0608 ,  B25J15/12 ,  B62D57/032 ,  Y10S901/27 ,  Y10S901/37 ,  Y10S901/39

Abstract: Reconfigurable soft robotic actuators with hard components are described. Magnetic attraction is used to couple flexible molded bodies capable of actuation upon pressurization with other flexible molded bodies and/or with hard components (e.g., frames and connectors) to form a seal for fluidic communication and cooperative actuation. Pneumatic de-coupling chambers built into the hard components to de-couple the hard components from the magnetically-coupled soft molded bodies are described. The use of magnetic self-alignment coupling and pneumatic de-coupling allows for the remote assembly and disassembly of complex structures involving hard and soft components. The magnetic coupling allows for rapid, reversible reconfiguration of hybrid soft-hard robots for repair, testing new designs, and carrying out new tasks.

公开(公告)号：EP2257819A4

公开(公告)日：2017-10-11

申请号：EP09725887

申请日：2009-03-27

Applicant: HARVARD COLLEGE

Inventor： CARRILHO EMANUEL ,  MARTINEZ ANDRES W ,  MIRICA KATHERINE A ,  PHILLIPS SCOTT T ,  SIEGEL ADAM C ,  WILEY BENJAMIN ,  WHITESIDES GEORGE M

IPC: B01L3/00 ,  F16K99/00 ,  G01N33/48 ,  G01N35/00

CPC classification number: B01L3/502707 ,  B01L3/5023 ,  B01L3/502738 ,  B01L7/525 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/0874 ,  B01L2300/0887 ,  B01L2300/126 ,  B01L2300/1855 ,  B01L2300/1877 ,  B01L2400/0406 ,  B01L2400/0633 ,  B01L2400/0672 ,  F16K99/0001 ,  F16K99/0015 ,  F16K99/0025 ,  F16K2099/008

公开(公告)号：EP3052303A4

公开(公告)日：2017-06-28

申请号：EP14863502

申请日：2014-10-02

Applicant: HARVARD COLLEGE

Inventor： TAYI ALOK ,  SO JU-HEE ,  WITTBRACHT FRANK ,  NUNES RUI ,  SHEPHERD ROBERT F ,  WHITESIDES GEORGE M

IPC: B29C70/34 ,  B29C70/40 ,  B29C70/86 ,  B32B1/08 ,  B32B3/10 ,  B32B5/26 ,  B32B5/28 ,  B32B7/04 ,  B32B7/08 ,  B32B15/02 ,  B32B27/28 ,  B32B29/00 ,  B32B37/10 ,  B32B38/18

CPC classification number: B32B7/045 ,  B32B1/02 ,  B32B1/08 ,  B32B3/10 ,  B32B5/26 ,  B32B7/08 ,  B32B15/02 ,  B32B29/005 ,  B32B37/10 ,  B32B37/1018 ,  B32B38/1808 ,  B32B2250/44 ,  B32B2260/021 ,  B32B2260/023 ,  B32B2260/028 ,  B32B2260/046 ,  B32B2262/062 ,  B32B2262/103 ,  B32B2262/106 ,  B32B2274/00 ,  B32B2305/07 ,  B32B2305/18 ,  B32B2307/538 ,  B32B2307/542 ,  B32B2535/00

公开(公告)号：EP2265958A4

公开(公告)日：2016-10-19

申请号：EP09724148

申请日：2009-03-27

Applicant: HARVARD COLLEGE

Inventor： SIEGEL ADAM C ,  PHILLIPS SCOTT T ,  DICKEY MICHAEL D ,  ROZKIEWICZ DOROTA ,  WILEY BENJAMIN ,  WHITESIDES GEORGE M ,  MARTINEZ ANDRES W

IPC: G01N35/00 ,  B01L3/00 ,  G01N27/26 ,  G01N33/48

CPC classification number: B01L3/502707 ,  B01L2200/027 ,  B01L2200/0642 ,  B01L2200/10 ,  B01L2200/12 ,  B01L2200/16 ,  B01L2300/025 ,  B01L2300/0636 ,  B01L2300/0645 ,  B01L2300/0809 ,  B01L2300/0819 ,  B01L2300/087 ,  B01L2300/12 ,  B01L2300/126 ,  B01L2300/161 ,  B01L2300/1827 ,  B01L2400/0406 ,  Y10T436/25 ,  Y10T436/2575

公开(公告)号：EP1991668A4

公开(公告)日：2011-06-15

申请号：EP07861227

申请日：2007-02-05

Applicant: HARVARD COLLEGE

Inventor： PARKER KEVIN KIT ,  FEINBERG ADAM W ,  WHITESIDES GEORGE M ,  SHEVKOPLYAS SERGEY S ,  FEIGEL ALEXANDER

IPC: C12N5/071 ,  C12N5/077

CPC classification number: G01N33/5061 ,  C12N5/0062 ,  C12N5/0657 ,  C12N2533/30 ,  C12N2533/52 ,  C12N2539/10 ,  G01N2500/10

公开(公告)号：EP2265959A4

公开(公告)日：2011-04-27

申请号：EP09724164

申请日：2009-03-27

Applicant: HARVARD COLLEGE

Inventor： DERDA RATMIR ,  LAROMAINE SAGUE ANNA ,  WHITESIDES GEORGE M

IPC: G01N35/00 ,  C12Q1/02 ,  G01N33/48

CPC classification number: G01N33/548 ,  B01J19/0046 ,  B01J2219/00527 ,  B01J2219/00605 ,  B01J2219/00619 ,  B01J2219/00641 ,  B01J2219/00644 ,  B01J2219/00743 ,  B01L3/5085 ,  B01L2300/0819 ,  B01L2300/0829 ,  B01L2300/126 ,  B01L2300/161 ,  G01N33/502

Abstract: Three-dimensional cellular arrays, methods of making three-dimensional cellular arrays, and methods of identifying agents using the arrays are disclosed.

公开(公告)号：EP2167216A4

公开(公告)日：2011-03-09

申请号：EP08826080

申请日：2008-06-30

Applicant: HARVARD COLLEGE

Inventor： PHILLIPS SCOTT T ,  WHITESIDES GEORGE M ,  MIRICA KATHERINE A ,  CARRILHO EMANUEL ,  MARTINEZ ANDRES W ,  SHEVKOPLYAS SERGEY S ,  SNYDER PHILLIP W ,  PEREZ-CASTILLEJOS RAQUEL ,  GUPTA MALANCHA ,  WINKLEMAN ADAM ,  GUDIKSEN KATHERINE L

IPC: B01D35/06 ,  B01L3/00

CPC classification number: G01N33/5434 ,  B01L3/502761 ,  B01L3/502776 ,  B01L3/50825 ,  B01L2200/0652 ,  B01L2300/045 ,  B01L2300/0877 ,  B01L2300/089 ,  B01L2400/043 ,  B01L2400/0457 ,  B01L2400/0487 ,  G01N33/54333 ,  G01R33/1269