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公开(公告)号:CA2751097A1
公开(公告)日:2010-08-05
申请号:CA2751097
申请日:2010-01-29
Applicant: MAUNA KEA TECHNOLOGIES
Inventor: VERCAUTEREN TOM , PERCHANT AYMERIC , LACOMBE FRANCOIS , SAVOIRE NICOLAS
Abstract: A method for processing images acquired in real time through a medical device, said images being loaded into a buffer, comprising the steps of : stopping the loading of the images into the buffer, processing loaded images using an incremental algorithm, displaying successively intermediate results of the processing, resuming the loading and stopping the processing based on an evaluation of said intermediate results.
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152.
公开(公告)号:FR2922308A1
公开(公告)日:2009-04-17
申请号:FR0758236
申请日:2007-10-11
Applicant: MAUNA KEA TECHNOLOGIES SOC PAR
Inventor: VIELLEROBE BERTRAND , LACOMBE FRANCOIS , BOULAROT NICOLAS , DOUSSOUX FRANCOIS , LAVILLONNIERE NICOLAS
Abstract: La présente invention concerne un dispositif d'imagerie, comprenant : un module d'illumination (1) comprenant des moyens pour émettre au moins un faisceau d'excitation ; un module de balayage et d'injection (2) comprenant un guide d'image (3) dont deux extrémités respectivement proximale (3a) et distale (3b) sont reliées par une pluralité de fibres optiques, et des moyens (6) de balayage et d'injection agencés pour injecter l'au moins un faisceau d'excitation tour à tour dans une fibre du guide d'image (3) et du côté proximal (3a) du guide ; un module de détection (4) comprenant des moyens pour détecter un flux lumineux (14) collecté à l'extrémité distale (3b) du guide. Au moins un parmi le module d'illumination (1) et le module de détection (4) est conjugué optiquement au module de balayage et d'injection (2) par une fibre optique de conjugaison (5, 7). L'utilisation de fibres de conjugaison (5, 7) permet d'améliorer la maintenance, la réparation et la mise à jour du dispositif, et peut en outre permettre de réaliser un filtrage modal du faisceau d'excitation et d'assurer la confocalité du dispositif.
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公开(公告)号:FR2899088B1
公开(公告)日:2008-06-27
申请号:FR0602793
申请日:2006-03-31
Applicant: MAUNA KEA TECHNOLOGIES SOC PAR
Inventor: ABRAT BENJAMIN , CAVE CHARLOTTE , LOISEAU ALEXANDRE , LOPEZ JEROME , OSDOIT ANNE , VIELLEROBE BERTRAND
Abstract: The method involves utilizing a confocal endo-microscopy system for detecting fluorescence signals emitted by methylene blue injected into a sample (13) e.g. biological tissue, where the system has an image guide (6) constituted of a flexible optical fiber for exciting the tissue by scanning a light beam e.g. laser beam. The light beam has wavelength ranging between 600-680 nanometers, and the methylene blue has a concentration ranging between 0.1-0.01 percentages.
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公开(公告)号:FR2865538B1
公开(公告)日:2007-10-19
申请号:FR0400580
申请日:2004-01-22
Applicant: CENTRE NAT RECH SCIENT , OBSERVATOIRE PARIS , MAUNA KEA TECHNOLOGIES
Inventor: LACOMBE FRANCOIS , LAFAILLE DAVID
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公开(公告)号:FR2864438B1
公开(公告)日:2006-11-17
申请号:FR0315627
申请日:2003-12-31
Applicant: MAUNA KEA TECHNOLOGIES
Inventor: MATHIEU GILLES , GENET MAGALIE , VIELLEROBE BERTRAND , BERIER FREDERIC
IPC: A61B1/07 , A61B1/00 , A61B1/005 , A61B1/04 , A61B1/05 , A61B5/00 , G02B6/06 , G02B6/26 , G02B6/35 , G02B7/02 , G02B21/00 , G02B26/08 , G02B26/10 , H01J3/14
Abstract: The head has a laser source to produce a light beam (13), and a ball lens (12), with a large numerical aperture, disposed at the end of the head to converge the beam at an excitation point (19). The point is located in an observed sub-surface field (14) of a sample (15). A scanning unit (10) displaces the source in rotation such that the point scans the field. An independent claim is also included for a confocal imaging system.
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公开(公告)号:FR2868279B1
公开(公告)日:2006-06-09
申请号:FR0403519
申请日:2004-04-02
Applicant: MAUNA KEA TECHNOLOGIES SOC PAR
Inventor: LACOMBE FRANCOIS , LE GOUALHER GEORGES , PERCHANT AYMERIC , AYACHE NICHOLAS
IPC: A61B5/00 , A61B3/12 , G01F1/00 , G01F1/708 , G01N15/14 , G01P5/00 , G01S15/89 , G02B21/00 , G02B23/26 , G02B26/10
Abstract: The invention relates to a method for measuring the speed of a particle such as a red blood cell moving inside a flow such as a flow of the blood, using a light scanning microscope. The inventive method comprises the following steps: acquisition of an image by x and y light scanning on a plane containing the object; detection on the plane (x, y) of a mark on the plane (x, y); estimation of the speed vg of the object from the gradient thus determined.
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157.
公开(公告)号:IL166151D0
公开(公告)日:2006-01-15
申请号:IL16615105
申请日:2005-01-05
Applicant: MAUNA KEA TECHNOLOGIES
IPC: G01N21/64 , A61B1/00 , A61B1/04 , A61B5/00 , G02B21/00 , G02B23/24 , G02B23/26 , G02B26/10 , H04N1/028 , A61B
Abstract: The method consists in deflecting the excitation signal at a speed corresponding to acquisition of a number of images per second sufficient for real time use and in detecting the fluorescence signal at a detecting frequency corresponding to a minimum frequency for sampling the fibers one by one. The method uses an image guide consisting of several thousands of optical fibers, an excitation signal being emitted by a source, deflected and injected by turns into the optical fibers of the guide, each excitation point of the tissue in the fiber output emitting in return a fluorescence signal collected by the fiber, then detected and digitized to form an image element. The method also provides for the focussing of the beam in the fiber output to excite a subsurface plane to produce a confocal image. The method also provides for the production of a divergent beam in the fiber output capable of exciting a micro-volume of the tissue from the surface.
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公开(公告)号:CA2561770A1
公开(公告)日:2005-10-20
申请号:CA2561770
申请日:2005-03-25
Applicant: MAUNA KEA TECHNOLOGIES
Inventor: LACOMBE FRANCOIS , LE GOUALHER GEORGES , PERCHANT AYMERIC , AYACHE NICHOLAS
Abstract: L~invention concerne un procédé pour mesurer la vitesse d~une particule tell e qu~un globule rouge en mouvement au sein d~un écoulement, tel qu~un flux sanguin, à partir d~un microscope à balayage lumineux, ce procédé comprenant les étapes suivantes: acquisition d~une image par balayage lumineux en x et y d~un plan contenant ledit objet; détection dans le plan (x, y) d~une strie engendrée par le déplacement dudit objet lors de l~acquisition de ladite ima ge ; détermination de la pente de ladite strie dans le plan (x, y) ; estimation de la vitesse vg dudit objet à partir de la pente ainsi déterminée.
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公开(公告)号:DE60205408D1
公开(公告)日:2005-09-08
申请号:DE60205408
申请日:2002-12-20
Applicant: MAUNA KEA TECHNOLOGIES PARIS
Inventor: VIELLEROBE BERTRAND , GENET MAGALIE , BERIER FREDERIC , LACOMBE FRANCOIS , PERCHANT AYMERIC , LE GOUALHER GEORGES , MARTI SANDRA , BOURRIAUX STEPHANE
Abstract: Equipment includes an image guide ( 1 ) consisting of flexible optical fibers with: on the proximal end side: a source ( 2 ), angular scanning elements ( 3 ), injection elements ( 4 ) in one of the fibers, elements for splitting ( 5 ) the illuminating beam and the backscattered signal, elements for spatial filtering ( 6 ), elements for detecting ( 7 ) the signal, electronic elements ( 8 ) for controlling, analyzing and digital processing of the detected signal and display; and on the distal end side: an optical head ( 9 ) for focusing the illuminating beam exiting from the illuminated fiber. The scanning elements include a resonant line mirror (M 1 ) and a galvanometric field mirror (M 2 ) with a variable frequency and two afocal optical systems adapted to conjugate the two mirrors (M 1 , M 2 ) firstly in the field mirror (M 2 ) and the injection elements ( 4 ) in the image guide in a second step.
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公开(公告)号:CA2553743A1
公开(公告)日:2005-09-01
申请号:CA2553743
申请日:2005-01-21
Applicant: MAUNA KEA TECHNOLOGIES , CENTRE NAT RECH SCIENT , OBSERVATOIRE PARIS
Inventor: LAFAILLE DAVID , LACOMBE FRANCOIS
Abstract: Dispositif pour mesurer le contraste des franges dans un interféromètre de Michelson en plein champ, comprenant un prisme de Wollaston pour dévier deux polarisations perpendiculaires entrantes dans deux directions émergeantes différentes, ces moyens de déviation étant disposés au sein de l'interféromètre en substitution d'un polariseur unique. Ce dispositif est appliqué dans un interféromètre de Michelson mis en oeuvre dans un système d e tomographie OCT et comprenant des moyens d'extraction du contraste interférométrique n'employant aucune technique de modulation ni des méthodes de détection synchrone.
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