Abstract:
본발명은엘라그산을함유하는복분자추출물의제조방법및 엘라그산의분리방법에관한것이다. 본발명에따르면복분자로부터추출한엘라그산을함유하는복분자추출물및 엘라그산을분리정제하는데최적의조건을확립함으로써, 추출물의활성을극대화하였다. 특히, 본발명의엘라그산을함유한복분자추출물및 이로부터분리된엘라그산은인플루엔자바이러스에대해높은저해활성을보이면서도세포독성이낮으므로인플루엔자바이러스에관련된질환의치료에효과적으로사용될수 있다.
Abstract:
PURPOSE: A mixture of a Prunella vulgaris extract and an Artemisia argyi herb extract is provided to suppress PTP1B(protein tyrosine phosphatase B1), and to prevent or treat diabetes. CONSTITUTION: A composition for suppressing PTP1B contains a Prunella vulgaris extract and/or an Artemisia argyi herb extract in a ratio of 1:1. A drug composition contains the composition for suppressing PTP1B as an active ingredient. A health food composition contains the composition for suppressing PTP1B as an active ingredient. A method for preparing the composition for suppressing PTP1B comprises: a step of extracting Prunella vulgaris and Artemisia argyi herb with water and filtering; a step of concentrating the liquid; and a step of drying the concentrate. [Reference numerals] (AA,EE) Control group; (BB,GG) Artemisia argyi herb; (CC,FF) Prunella vulgaris; (DD,HH) Mixture of Prunella vulgaris and Artemisia argyi herb
Abstract:
본 발명은 구강 항균활성을 갖는 잔소리 졸의 제조방법에 관한 것으로, 더욱 상세하게는 커큐마 잔소리자 분말에 유기용매를 혼합하여 항균활성 물질을 추출하는 추출단계, 항균활성 물질이 추출된 유기용매 혼합물을 분리하는 분리단계, 전술한 분리단계를 거쳐 분리된 유기용매 혼합물에 함유된 유기용매를 제거하는 용매제거단계, 유기용매가 제거된 조추출물을 전처리하는 전처리단계, 전처리된 조추출물에 함유된 비극성 물질을 제거하는 비극성물질제거단계, 비극성물질이 제거되어 분획된 추출물을 아세틸레이션하는 아세틸레이션단계, 전술한 아세틸레이션단계를 거친 추출물을 극성차이에 따라 분리하는 항균활성물질분리단계 및 전술한 항균활성물질을 디아세틸레이션하는 디아세틸레이션단계를 포함하여 이루어진다.
Abstract:
PURPOSE: An anti-allergic composition containing Scrophularia buergeriana extract is provided to ensure allergic disease cell apoptotic effect and to suppress allergic disease transfer. CONSTITUTION: An anti-allergic composition contains Scrophularia buergeriana extract as an active ingredient. The extract is isolated using water, alcohol of 1-5 carbon atoms, or mixture thereof. A composition for preventing or treating allergic diseases contains the anti-allergic composition as an active ingredient. A food composition for preventing or treating allergic diseases contains the anti-allergic composition as an active ingredient.
Abstract:
본 발명은 고춧가루를 용매를 이용하여 펙틴을 추출하고, 상기 추출된 펙틴을 검정곰팡이(Aspergillus niger)로 발효시켜 생성되는 변형고추펙틴(MCP, Modified Capsicum Pectin)과, 그 제조방법 및 용도에 관한 것이다. 즉, 본 발명은 고춧가루로부터 펙틴을 함유한 추출물을 검정곰팡이(Aspergillus niger)로 발효시켜서, 고추 세포벽을 구성하고 있는 펙틴(pectin)화합물이 검정곰팡이(Aspergillus niger)로부터 분비되는 엔도폴리갈락투로나아제(endopolygalacturonase) 및 펙틴 메틸에스테라제(pectin methylesterase)에 의해 분해가 되도록 하여, 변형고추펙틴을 제조하는 방법을 제시한다. 또한, 본 발명은 상기 제조된 변형고추펙틴(MCP)이 중금속(heavy metal)과 복합체 반응(Chelation)을 일으키는 것을 실험으로써 확인하여 장내 중금속 제거하는 효과가 있음을 밝혀내고, 시토킨(Cytokine) 유도 기능을 확인하여 인체면역성 증대 효과가 있음을 밝혀내고, 항산화 활성기능을 확인하여 항암 및 노화방지 효과가 있음을 밝혀낸다. 이를 통해, 상기 변형고추펙틴(MCP)을 유효한 성분으로 하는 식품(또는 조성물)은 장내 중금속 제거와, 인체면역성 증대, 항암 및 노화방지 효과를 가지는 기능성 식품으로서 활용이 가능함을 제시한다. 고추, 펙틴, 변형고추펙틴, 중금속, 엔도폴리갈락투로나아제, 시토킨, 산화스트레스, 펙틴메틸에스테라아제, 발효, 기능성식품, red pepper, pectin, modified capsicum pectin, MCP, heavy metals, endopolygalacturonase, cytokines, oxidative stress, pectin methylesterase, fermentation, functional food
Abstract:
PURPOSE: A method for manufacturing seasoning material containing anchovies through enzymatic decomposition at high pressure is provided to produce seasoning material with high functionality, abundant flavor and high nutrition. CONSTITUTION: A method for manufacturing seasoning material containing anchovies comprises: a step of pulverizing dried anchovies; a step of dispersing pulverized anchovies in water; a step of adding 0.4-0.8 weight% of enzyme; a step of adjusting pH at 6.0-8.0; a step of pressurizing at 50-125MPa and 40-60°C for 12 to 24 hours; a step of centrifuging the anchovy slurry to obtain hydrolysate; a step of filtering the hydrolysate; a step of boiling at 95-100°C to inactivate the enzyme; and a step of collecting solid content.
Abstract:
A method for isolating a xanthorrizole which has antibacterial activity is provided to shorten extraction time and improve yield of the extract without side effect. A method for producing a xanthorrizole having antibacterial activity from a Curcuma xanthorriza: a step of pulverizing Curcuma xanthorriza; a step of extracting using ethanol or hexane solvent; a step of isolating solvent layer; a step of removing the solvent; and a step of removing nonpolar material by chromatography.
Abstract:
An oral composition for preventing tooth-decay, containing fennel extract and an antibiotic composition is provided to be stable at a high temperature and to perform processing at a temperature of wide range. An oral composition for preventing tooth-decay comprises FENNEL extract by hot water and FENNEL extract by organic solvent as an active ingredient. The oral composition comprises one formulation selected from a group consisting of oral cleaner, dentifrice, gum, candy, jelly and chocolate. The organic solvent is selected from a group consisting of C1-C6 alcohol, acetone, ether, benzene, chloroform, ethylacetate, methylene chloride, hexane, cyclohexane, and petroleum ether.