GCPⅡ 돌연변이를 함유하는 알츠하이머 예방 및 치료용 약학적 조성물
    11.
    发明授权
    GCPⅡ 돌연변이를 함유하는 알츠하이머 예방 및 치료용 약학적 조성물 有权
    预防和治疗包含GCP II突变体的阿尔茨海默病的药物组合物

    公开(公告)号:KR101164645B1

    公开(公告)日:2012-07-20

    申请号:KR1020110102610

    申请日:2011-10-07

    Abstract: PURPOSE: A pharmaceutical composition containing GCP II mutant is provided to ensure excellent A beta decomposition and stability and to prevent or treat Alzheimer's disease. CONSTITUTION: A pharmaceutical composition for preventing and treating Down syndrome, stroke, dementia, Huntington disease, Pick disease, or Creutzfeid-Jakob contains GCP II mutant as an active ingredient, which is mutated from 699th amino acid, lysine to serine in a total amino acid sequence of GCP II(glutamate carboxypeptidase II). The mutant has an amino acid sequence of sequence number 2.

    Abstract translation: 目的:提供含有GCP II突变体的药物组合物,以确保优异的Aβ分解和稳定性,并预防或治疗阿尔茨海默氏病。 构成:用于预防和治疗唐氏综合征,中风,痴呆,亨廷顿舞蹈病,皮克病或克id id雅各布的药物组合物含有GCP II突变体作为活性成分,其从第699位氨基酸,赖氨酸突变为丝氨酸,总氨基酸 GCP II(谷氨酸羧肽酶II)的酸序列。 突变体具有序列号2的氨基酸序列。

    콩 발아배아 추출물을 포함하는 골다공증의 예방 또는 치료용 약학 조성물
    12.
    发明公开
    콩 발아배아 추출물을 포함하는 골다공증의 예방 또는 치료용 약학 조성물 审中-实审
    用于预防或治疗骨质疏松症的药物组合物,包括大豆发芽的胚胎提取物

    公开(公告)号:KR1020170054115A

    公开(公告)日:2017-05-17

    申请号:KR1020150156866

    申请日:2015-11-09

    CPC classification number: A61K31/7048 A61K36/48

    Abstract: 본발명은콩 발아배아추출물을포함하는골다공증의예방또는치료용약학조성물에관한것으로, 구체적으로콩 발아배아추출물또는이의분획물을포함하는골다공증의예방또는치료용약학조성물, 상기조성물을인간을제외한개체에투여하는단계를포함하는골다공증의예방또는치료방법, 콩발아배아추출물또는이의분획물을포함하는골다공증의예방또는개선용식품조성물, 및사료조성물에관한것이다. 본발명의콩 발아배아추출물은조골세포의증식능및 분화능을향상시키며, 골밀도, 골부피및 골세포의수를증가시키는효과를나타내므로, 골다공증의예방또는치료에유용하게사용될수 있다.

    Abstract translation: 本发明涉及一种用于预防和治疗包含豆类骨质疏松的发芽胚胎提取物的药物组合物,特别是大豆发芽胚胎提取物或用于预防和治疗骨质疏松症的药物,包含该组合物的一小部分,除了人类的组合物 涉及预防或治疗骨质疏松症的方法包括向对象施用,发芽豆胚芽提取物或食品为骨质疏松症的包含该组合物和饲料组合物的一小部分的预防或改善。 发芽豆的本发明的提取物的胚胎显示出改善成骨细胞和多能的增殖,增加骨量,骨体积和骨细胞的数目,可以在预防或治疗骨质疏松症的有用的效果。

    경도인지장애 진단용 바이오마커
    13.
    发明公开
    경도인지장애 진단용 바이오마커 无效
    用于诊断小儿认知障碍的生物标志物

    公开(公告)号:KR1020160006432A

    公开(公告)日:2016-01-19

    申请号:KR1020140085985

    申请日:2014-07-09

    CPC classification number: C12Q1/6813 C12Q1/6844

    Abstract: 본발명은 MCI(경도인지장애) 진단용바이오마커및 그유전자의 mRNA 또는이의단백질발현수준을측정하는제제를포함하는 MCI 진단용키트와이를이용한 MCI 진단방법에관한것이다. 본발명의상기 MCI 진단용 PAI1 바이오마커는 MCI를가진사람에게서정상인에비해유의성있게증가해있으므로, MCI 진단용바이오마커, MCI진단용키트및 MCI 진단방법에유용하게사용될수 있다.

    Abstract translation: 本发明涉及用于诊断轻度认知障碍(MCI)的生物标志物,用于诊断MCI的试剂盒,其包含测量mRNA或其基因的蛋白质的表达水平的制剂,以及使用其的MCI诊断方法。 用于诊断MCI患者的MCI的本发明中的PAI1生物标志物与正常人相比显着增加,从而可用于MCI诊断生物标志物,MCI诊断试剂盒和MCI诊断方法。

    엑스레이 촬영을 통한 어류용 백신 접종위치 추종 알고리즘
    18.
    发明授权
    엑스레이 촬영을 통한 어류용 백신 접종위치 추종 알고리즘 有权
    使用X射线摄影法确定鱼类疫苗注射位置的算法

    公开(公告)号:KR101444211B1

    公开(公告)日:2014-09-30

    申请号:KR1020130158566

    申请日:2013-12-18

    Abstract: The present invention relates to an algorithm by which a fish abdominal position for vaccine injection is determined based on morphological measurement data including the total length (TL), the body width (WL), and the weight (W) of the fish. More particularly, according to the fish vaccine injection position following algorithm of the present invention, abdominal position and shape including a linear distance (ML) from a mouth end portion to the abdomen, the length of the abdomen (AL), and the width of the abdomen (AW) are detected through fish X-raying and weight center point coordinates of an injection area where an internal organ is absent are obtained with the ML line being the x axis and the AW line being the y axis. Then, the coordinates are deduced into an equation using TL, TL and WL, or TL, WL, and W as variables, that is, morphological injection position coordinates. According to the present invention, the injection position following can be more accurate than in the related art in which the correlation between the total length and the body width of the fish and the like are analyzed for morphological injection position following based on an injection position manually marked on an outer surface of the fish body by an injection specialist. Also, according to the present invention, damage to the internal organ attributable to the vaccine injection can be minimized. In addition, the present invention can be effectively applied to various types of automated vaccine injection devices, including the automated vaccine injection devices of the related art in which a vision system and a rectangular coordinates robot are used.

    Abstract translation: 本发明涉及一种基于包括鱼的总长(TL),体宽(WL)和重量(W))的形态学测量数据来确定用于疫苗注射的鱼腹部位置的算法。 更具体地,根据本发明的鱼疫苗注射位置跟随算法,腹部位置和形状包括从口端部到腹部的线性距离(ML),腹部长度(AL)和宽度 通过鱼X射线检测腹部(AW),并且通过ML线为x轴并且AW线为y轴,获得不存在内脏的注射区域的体重中心点坐标。 然后,使用TL,TL和WL或TL,WL和W作为变量,即形态注入位置坐标,将坐标推导到等式中。 根据本发明,以下的注射位置可以比现有技术更准确,其中分析了基于手动的注射位置的跟随的形状注射位置之间的鱼等的总长度和体宽之间的相关性 由注射专家在鱼体的外表面标记。 另外,根据本发明,由于疫苗注射引起的内部器官的损伤能够最小化。 此外,本发明可以有效地应用于各种类型的自动疫苗注射装置,包括其中使用视觉系统和直角坐标机器人的现有技术的自动疫苗注射装置。

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