-
公开(公告)号：KR1020120051196A
公开(公告)日：2012-05-22
申请号：KR1020100112506
申请日：2010-11-12
Applicant: 주식회사 바이오노트 , 대한민국(농림축산식품부 농림축산검역본부장)
Abstract: PURPOSE: A kit for diagnosing bovine tuberculosis containing monoclonal antibodies and polyclonal antibodies is provided to effectively measure tuberculosis attack. CONSTITUTION: A monoclonal antibody which specifically binds to an epitope is denoted by an amino acid sequence of sequence number 8 in a bovine interferon gamma receptor-binding region. The monoclonal antibody is produced from hydridoma cells(deposit number KCTC 11784BP). A kit for diagnosing bovine contains monoclonal antibody or antigen binding fragment and anti-bovine interferon gamma polyclonal antibody.
Abstract translation: 目的：提供用于诊断含有单克隆抗体和多克隆抗体的牛结核的试剂盒，以有效测量结核病的发作。 构成：特异性结合表位的单克隆抗体由牛干扰素γ受体结合区中的序列号8的氨基酸序列表示。 单克隆抗体由Hydridoma细胞（保藏号KCTC 11784BP）产生。 用于诊断牛的试剂盒含有单克隆抗体或抗原结合片段和抗牛干扰素γ多克隆抗体。
-
公开(公告)号：KR1020110009638A
公开(公告)日：2011-01-28
申请号：KR1020100070745
申请日：2010-07-22
Applicant: 대한민국(농림축산식품부 농림축산검역본부장)
CPC classification number: A23K10/18 , A23K20/195 , C12N1/20 , C12R1/225
Abstract: PURPOSE: A feed additive composition including novel lactobacillus species lactobacillus mixed bacterial strain is provided to offer the excellent antibacterial activity and starch resolution function for various pathogenic bacteria. CONSTITUTION: A feed additive composition contains a lactobacillus mixed bacterial strain formed with lactobacillus johnsonii G22-2, lactobacillus reuteri G8-5, and lactobacillus salivarius G1-1. The lactobacillus mixed bacterial strain has the antimicrobial activity against pathogenic bacteria, the starch degradation capability, the acid resistance, the bile tolerance, and the intestine adhesion capability.
Abstract translation: 目的：提供包含新型乳酸杆菌种乳杆菌混合菌株的饲料添加剂组合物，为各种病原菌提供优异的抗菌活性和淀粉分解功能。 构成：饲料添加剂组合物含有由约翰逊乳杆菌G22-2，乳酸杆菌G8-5和唾液乳杆菌G1-1形成的乳杆菌混合菌株。 乳杆菌混合菌株对病原菌具有抗菌活性，淀粉降解能力，耐酸性，胆汁耐受性和肠粘连能力。
-
公开(公告)号：KR1020110009516A
公开(公告)日：2011-01-28
申请号：KR1020090066955
申请日：2009-07-22
Applicant: 대한민국(농림축산식품부 농림축산검역본부장)
Abstract: PURPOSE: A feed additive composition containing Lactobacillus salivarius G1-1 is provided to ensure antibacterial activity to various pathogenic bacteria and to be used as a probiotic composition. CONSTITUTION: A Lactobacillus salivarius G1-1 is deposited in KACC91449P. The Lactobacillus salivarius G1-1 has 16s rDNA of sequence number 1 and is isolated from porcine small intestine by pure culture. A feed additive composition contains the Lactobacillus salivarius G1-1 as an active ingredient. The feed additive suppresses in vivo proliferation of pathogenic bacteria.
Abstract translation: 目的：提供含有唾液乳杆菌G1-1的饲料添加剂组合物，以确保对各种病原菌的抗菌活性，并用作益生菌组合物。 构成：唾液乳杆菌G1-1保藏在KACC91449P中。 唾液乳杆菌G1-1具有序列1的16s rDNA，通过纯培养从猪小肠中分离。 饲料添加剂组合物含有唾液乳杆菌G1-1作为活性成分。 饲料添加剂抑制致病菌的体内增殖。
-
公开(公告)号：KR100951055B1
公开(公告)日：2010-04-06
申请号：KR1020070093644
申请日：2007-09-14
Applicant: 대한민국(농림축산식품부 농림축산검역본부장)
IPC: A61K36/344 , A61P37/02
Abstract: 본 발명은 동물의 면역능을 증강시키는 더덕 추출물 및 그 제조방법과 용도에 관한 것이다. 보다 상세하게는 더덕줄기 및 잎을 음지에서 건조시켜 마쇄하여 열탕용 봉지에 넣고 증류수 중에 가열하여 1차 추출한 후, 추출물은 별도로 분리하고 잔류물에 재차 증류수를 넣고 열탕하여 2차 추출하여 추출물을 얻는 단계와, 1차 및 2차 추출물을 혼합하여 추출물에 2배량의 에탄올을 가하여 4∼6℃ 냉장실에서 24시간 정치시켜 침전된 다당체를 원심분리하는 단계와, 분리된 다당체를 순수 에탄올로 원심 세척한 후 35∼38℃ 항온실에서 건조하여 증류수로 1mg/ml 농도로 용해시켜 세균여과지로 여과하여 원액을 얻는 단계로 구성된다.
본 발명의 더덕추출물은 동물의 주요 면역세포인 호중구의 각종 활성과 싸이토카인 생성을 증강시키고 병원성세균의 공격접종에 대한 비특이적인 방어능을 증진시키는 효과가 있으므로 동물용 의약품으로써 면역증강제. 백신보좌제 첨가물 그리고 보조치료제 등으로 광범위하게 활용될 수 있을 것이다.-
公开(公告)号：KR1020090116190A
公开(公告)日：2009-11-11
申请号：KR1020080041975
申请日：2008-05-06
Applicant: 대한민국(농림축산식품부 농림축산검역본부장)
IPC: A61K39/002 , A61K39/00
CPC classification number: A61K39/002 , A61K2039/552 , Y10S424/823
Abstract: PURPOSE: A vaccine of neosporosis and a method for producing neosporosis are provided to induce infection of low level and prevent neosporosis. CONSTITUTION: A vaccine for bovine neosporosis contains Neospora caninum antigen. The vaccine further comprises Polygen^TM, IMS1313^TM, or PBS^TM as an adjuvant. A method for producing the vaccine comprises: a step of culturing Neospora protozoa in a cell; a step of collecting cultured Neospora protozoa; and a step of treating the Neospora protozoa with antigen.
Abstract translation: 目的：提供新孢子虫病疫苗和生产新孢子虫病的方法，以诱导低水平感染并预防新孢子虫病。 构成：牛新孢子虫病疫苗含有新孢子虫犬抗原。 疫苗还包含Polygen TM，IMS1313？TM或作为佐剂的PBS ^ TM。 疫苗的制造方法包括：在细胞中培养新孢子虫原生动物的步骤; 收集培养的新孢子虫原生动物的一个步骤; 以及用抗原处理新孢子虫原生动物的步骤。
-
Patent Agency Ranking
公开(公告)号：KR100918098B1
公开(公告)日：2009-09-24
申请号：KR1020070077854
申请日：2007-08-02
Applicant: 대한민국(농림축산식품부 농림축산검역본부장)
IPC: A61K39/02 , A61P37/02 , A61K39/085
Abstract: 본 발명은 스트렙토마이세스 알부스 용균 추출물을 포함하는 백신 보좌제에 관한 것으로, 보다 자세히는 스트렙토마이세스 알부스(Streptomyces albus) 용균 추출물을 이용하여 동물의 면역 능력을 향상시키는 백신 보좌제에 관한 것으로, 동물의 주요 면역세포인 호중구 및 림프구 등의 활성을 증가시켜 병원성 세균의 공격에 대하여 면역 기능을 증진시키는 스트렙토마이세스 알부스(Streptomyces Albus) 용균 추출물을 포함하는 백신 보좌제를 제공하는 것을 목적으로 한다.
본 발명은 이와 같은 스트렙토마이세스 알부스로부터 추출한 용균 추출물을 이용하여 질병 방어에 주요한 역할을 담당하고 있는 각종 면역세포들의 기능을 증강시켜 질병 감염에 대한 특이 및 비특이적 저항성을 높여서, 질병으로부터 동물을 보호할 수 있는 효과를 제공한다.
스트렙토마이세스 알부스, 용균 추출물, 면역-
17.发明公开면역특이단백질 항원을 사용하는 우결핵 특이 효소면역진단키트 및 이를 이용한 우결핵 진단방법 有权包含免疫特异性蛋白质抗原和其他免疫原的BOVINE TUBCCOSOS特异性酶免疫测定试剂盒及其使用方法诊断牛血管病毒
公开(公告)号：KR1020090052175A
公开(公告)日：2009-05-25
申请号：KR1020070118743
申请日：2007-11-20
Applicant: 대한민국(농림축산식품부 농림축산검역본부장)
Abstract: 본 발명은 우결핵 특이 효소면역진단 키트 및 이를 이용한 우결핵 진단방법에 관한 것으로, 보다 상세하게는 우결핵균의 단백질항원 중 면역특이단백질 항원인 MPB70 등을 이용한 효소면역측정법을 통하여 신속하고 정확하게 우결핵을 진단하는 우결핵 특이 효소면역진단 키트 및 이를 이용한 우결핵 진단방법에 관한 것이다.
우결핵, 정제단백질, 효소면역측정법, 피내검사-
公开(公告)号：KR1020090007086A
公开(公告)日：2009-01-16
申请号：KR1020070070724
申请日：2007-07-13
Applicant: 대한민국(농림축산식품부 농림축산검역본부장)
CPC classification number: C07K14/35 , C07K14/00 , G01N33/53 , G01N33/6854
Abstract: An immunity-specific protein antigen for diagnosis of bovine tuberculosis is provided to supply the information on the protein antigen which specifically and immunologically reacts with the blood serum of a subject infected by Mycobacterium bovis among protein antigens existing in the upper layer of the Mycobacterium bovis-cultured medium. The protein antigen is obtained from the upper layer of the cultured medium of Mycobacterium bovis which is tuberculous bacterium, comprises one or more amino acid seqeunces selected from the group consisting of SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, SEQ ID NO:6, SEQ ID NO:7, SEQ ID NO:8, SEQ ID NO:9, SEQ ID NO:10, SEQ ID NO:11, SEQ ID NO:12, SEQ ID NO:13, SEQ ID NO:14, SEQ ID NO:15, SEQ ID NO:16, SEQ ID NO:17, SEQ ID NO:18, SEQ ID NO:19, SEQ ID NO:20 and SEQ ID NO:21, and raises the immune response in the blood serum of the subject infected with Mycobacterium bovis.
Abstract translation: 提供了用于诊断牛结核病的免疫特异性蛋白质抗原，以提供与牛分枝杆菌分枝杆菌上层存在的蛋白质抗原中特异性和免疫学上与牛分枝杆菌感染的受试者血清特异性和免疫反应的蛋白质抗原的信息， 培养基。 蛋白质抗原是从作为结核菌的牛分枝杆菌培养基的上层得到的，包含一个或多个选自SEQ ID NO：1，SEQ ID NO：2，SEQ ID NO：1的氨基酸序列。 3，SEQ ID NO：4，SEQ ID NO：5，SEQ ID NO：6，SEQ ID NO：7，SEQ ID NO：8，SEQ ID NO：9，SEQ ID NO：10，SEQ ID NO： SEQ ID NO：12，SEQ ID NO：13，SEQ ID NO：14，SEQ ID NO：15，SEQ ID NO：16，SEQ ID NO：17，SEQ ID NO：18，SEQ ID NO：19， NO：20和SEQ ID NO：21，并且提高感染牛分枝杆菌的受试者的血清中的免疫应答。
-
公开(公告)号：KR1020080106789A
公开(公告)日：2008-12-09
申请号：KR1020070054645
申请日：2007-06-04
Applicant: 대한민국(농림축산식품부 농림축산검역본부장)
IPC: A61K36/236 , A61P37/02
Abstract: A Glycyrrhiza hot water extract, a method for preparing the extract, and an immune enhance containing the extract are provided to improve the immune increasing activity of animals. A Glycyrrhiza hot water extract is prepared by adding 1,000 mL of distilled water per 100 g of the dried Glycyrrhiza to soak Glycyrrhiza for 20-30 min and boiling it down for 150 min to obtain an extract; adding 800 mL of distilled water per 100 g of the dried Glycyrrhiza to the Glycyrrhiza remaining after the extraction and boiling it down for 150 min to obtain an extract; adding 700 mL of distilled water per 100 g of the dried Glycyrrhiza to the Glycyrrhiza remaining after the extraction and boiling it down for 150 min to obtain an extract; collecting the obtained extract and concentrating it; and dry-freezing the concentrated one.
Abstract translation: 提供甘草热水提取物，制备提取物的方法和含有提取物的免疫增强物，以提高动物的免疫增加活性。 通过向100g甘草中加入1000mL蒸馏水，将Glycyrrhiza浸泡20-30分钟，煮沸150分钟，得到甘草热水提取物，得到提取物; 向100g甘草中加入800毫升蒸馏水，然后将其蒸馏除去150分钟，得到提取物; 向100g甘草中加入700毫升蒸馏水至提取后剩余的甘草，煮沸150分钟，得到提取物; 收集所得提取物并浓缩; 并干燥浓缩浓缩的。
-
公开(公告)号：KR1020070104720A
公开(公告)日：2007-10-29
申请号：KR1020060036588
申请日：2006-04-24
Applicant: 대한민국(농림축산식품부 농림축산검역본부장)
IPC: C12N1/20
Abstract: An Enterohemorrhagic Escherichia coli(EHEC) strain isolated from Korean native cattle is provided to be used as a vaccine strain. And a toxoid vaccine for preventing an infectious disease of EHEC comprising an inactivated Shiga toxin produced from the strain is provided to prevent hemorrhagic diarrhea of a calf and induce the decrease of the infection in cattle, thereby being ultimately used for preventing an infectious disease of EHEC. An EC377 strain selected from EHEC derived from Korean native cattle produces shigatoxins 1(stx1) and has a plasma type of 055. An EC611 strain selected from the EHEC derived from Korean native cattle produces stx2 and has a plasma type of 06. An EC381 strain selected from the EHEC derived from Korean native cattle produces stx1 and stx2 and has a plasma type of 0153. 06. 55. A method for promoting the generation of Shiga toxins is characterized in that 0.5-1.0mug/ml of Mitomycin C is added during the culturing of the EHEC strains. A toxoid vaccine for preventing an infectious disease of EHEC comprises at least one Shiga toxins cStx1 and cStx2 toxoid antigen prepared by treating the shigatoxins with 0.2-0.5% of glutaraldehyde for 1-3 hours and then detoxicating it with 0.2-1.0% of lysine.
Abstract translation: 提供从韩国本地牛分离的肠出血性大肠杆菌（EHEC）菌株用作疫苗株。 并提供一种用于预防由该菌株产生的包含灭活的志贺毒素的EHEC感染性疾病的类毒素疫苗，以防止小牛的出血性腹泻并诱导牛的感染减少，从而最终用于预防EHEC的感染性疾病 。 选自源自韩国本地牛的EHEC的EC377菌株产生了起始的黄曲霉毒素1（stx1），血浆类型为055.选自来自韩国本地牛的EHEC的EC611菌株产生stx2，血浆类型为0.06。EC381菌株 选自源自韩国本地牛的EHEC产生stx1和stx2，并具有等离子体类型0153. 06. 55.一种用于促进滋贺毒素生成的方法，其特征在于在0.5-10.0μg/ ml丝裂霉素C中加入 培养EHEC菌株。 用于预防EHEC传染病的类毒素疫苗包含至少一种通过用0.2-0.5％戊二醛处理志贺菌素1-3小时制备的志贺毒素cStx1和cStx2类毒素抗原，然后用0.2-1.0％的赖氨酸对其进行解毒。
-
-
-
-
-
-
-
-
-
Search Results
124
records
(took 0.063 seconds)
