公开(公告)号：DE3312677A1

公开(公告)日：1983-10-13

申请号：DE3312677

申请日：1983-04-08

Applicant: ABBOTT LAB

Inventor： TADANIER JOHN SOLOMAN ,  HALLAS ROBERT

IPC: A61K31/70 ,  A61K31/7028 ,  A61K31/7034 ,  A61K31/7036 ,  A61P31/04 ,  C07H15/224 ,  C07D309/14 ,  A61K31/35

公开(公告)号：GR70195B

公开(公告)日：1982-08-31

申请号：GR800162830

申请日：1980-09-08

Applicant: ABBOTT LAB

Inventor： TADANIER JOHN SOLOMAN ,  HALLAS ROBERT ,  MARTIN JERRY ROY

IPC: A61K31/70 ,  A61K31/7028 ,  A61K31/7034 ,  A61K31/7036 ,  A61K31/7042 ,  A61P31/04 ,  C07H15/224 ,  C07H17/00

公开(公告)号：GR67757B

公开(公告)日：1981-09-22

申请号：GR800161540

申请日：1980-03-27

Applicant: ABBOTT LAB

Inventor： TADENIER JOHN SOLOMAN ,  HALLAS ROBERT ,  MARTIN JERRY ROY

IPC: C07H15/224

Abstract: What is described is 2-epi-fortimicin A, 2-epi-fortimicin B or a 2-epi-fortimicin B derivative represented by the formula: wherein R1 is hydrogen or loweralkyl; R2 is hydrogen or hydroxy; R3 is methyl or hydrogen; and R4 is selected from the group consisting of hydrogen, loweralkyl, aminoloweralkyl, diaminoloweralkyl, N-loweralkylaminoalkyl, N,N-diloweralkylaminoloweralkyl, hydroxyloweralkyl, aminohydroxyloweralkyl, N-loweralkylaminohydroxyloweralkyl, N,N-diloweralkylaminohydroxyloweralkyl, acyl of the formula wherein R5 is loweralkyl, aminoacyl, diaminoacyl, hydroxyacyl, N-loweralkylaminoacyl, N,N-diloweralkylaminoacyl, hydroxy-substituted aminoacyl or an amino acid residue other than those defined above and the pharmaceutically acceptable salts thereof useful in the treatment of infections.

公开(公告)号：FR2470126A1

公开(公告)日：1981-05-29

申请号：FR8020598

申请日：1980-09-25

Applicant: ABBOTT LAB

Inventor： TADANIER JOHN SOLOMAN ,  HALLAS ROBERT ,  MARTIN JERRY ROY

IPC: A61K31/70 ,  A61K31/7028 ,  A61K31/7034 ,  A61K31/7036 ,  A61K31/7042 ,  A61P31/04 ,  C07H15/224 ,  C07H17/00 ,  C07D309/10 ,  A61K31/35

公开(公告)号：DE2421269A1

公开(公告)日：1974-11-21

申请号：DE2421269

申请日：1974-05-02

Applicant: ABBOTT LAB

Inventor： HALLAS ROBERT ,  TADANIER JOHN SOLOMAN ,  ESCH ANNE MARY VON

IPC: A61K31/335 ,  A61K31/70 ,  A61K31/7042 ,  A61K31/7048 ,  A61P31/04 ,  C07H17/08 ,  C07D21/00

Abstract: Covers 4''-O-sulfonyl erythromycin-9-O-oxime derivatives falling within the following structural formula:

公开(公告)号：ES2218604T3

公开(公告)日：2004-11-16

申请号：ES96936579

申请日：1996-10-17

Applicant: ABBOTT LAB

Inventor： OR YAT SUN ,  PHAN LY TAM ,  CHU DANIEL T ,  SPINA KENNETH P ,  HALLAS ROBERT ,  ELLIOTT RICHARD L

IPC: C07H17/00 ,  A61K31/00 ,  A61K31/70 ,  A61K31/7042 ,  A61P31/00 ,  A61P31/04 ,  C07H17/08

Abstract: Compounds, or pharmaceutically acceptable salts and esters thereof, of formulae (I); (II); (III) or (IV) wherein A, B, D and E, R , R and Z are specifically defined, having antibacterial activity, pharmaceutical compositions containing said compounds, treatment of antibacterial infections with such compositions, and processes for the preparation of the compounds.

公开(公告)号：DE69631609D1

公开(公告)日：2004-03-25

申请号：DE69631609

申请日：1996-10-17

Applicant: ABBOTT LAB

Inventor： OR SUN ,  PHAN TAM ,  CHU T ,  SPINA P ,  HALLAS ROBERT ,  ELLIOTT L

IPC: C07H17/00 ,  A61K31/00 ,  A61K31/70 ,  A61K31/7042 ,  A61P31/00 ,  A61P31/04 ,  C07H17/08

Abstract: Compounds, or pharmaceutically acceptable salts and esters thereof, of formulae (I); (II); (III) or (IV) wherein A, B, D and E, R , R and Z are specifically defined, having antibacterial activity, pharmaceutical compositions containing said compounds, treatment of antibacterial infections with such compositions, and processes for the preparation of the compounds.

公开(公告)号：AT259823T

公开(公告)日：2004-03-15

申请号：AT96936579

申请日：1996-10-17

Applicant: ABBOTT LAB

Inventor： OR YAT SUN ,  PHAN LY TAM ,  CHU DANIEL T ,  SPINA KENNETH P ,  HALLAS ROBERT ,  ELLIOTT RICHARD L

IPC: C07H17/00 ,  A61K31/00 ,  A61K31/70 ,  A61K31/7042 ,  A61P31/00 ,  A61P31/04 ,  C07H17/08

Abstract: Compounds, or pharmaceutically acceptable salts and esters thereof, of formulae (I); (II); (III) or (IV) wherein A, B, D and E, R , R and Z are specifically defined, having antibacterial activity, pharmaceutical compositions containing said compounds, treatment of antibacterial infections with such compositions, and processes for the preparation of the compounds.

公开(公告)号：CZ231599A3

公开(公告)日：1999-12-15

申请号：CZ231599

申请日：1997-04-07

Applicant: ABBOTT LAB

Inventor： OR YAT SUN ,  PHAN LY TAM ,  CHU DANIAL T ,  SPINA KENNATH P ,  HALLAS ROBERT ,  ELLIOTT RICHARD L ,  TUFANO MICHAEL

IPC: C07H17/00 ,  A61K31/00 ,  A61K31/70 ,  A61K31/7042 ,  A61K31/7048 ,  A61P31/00 ,  A61P31/04 ,  C07H17/08 ,  A61K31/71

Abstract: Compounds, or pharmaceutically acceptable salts and esters thereof, of the formula:wherein A, B, D and E, R1, R2, and Z are specifically defined, having antibacterial activity, pharmaceutical compositions containing said compounds, treatment of bacterial infections with such compositions, and processes for the preparation of the compounds.

公开(公告)号：AU7447096A

公开(公告)日：1997-05-29

申请号：AU7447096

申请日：1996-10-17

Applicant: ABBOTT LAB

Inventor： OR YAT SUN ,  PHAN LY TAM ,  CHU DANIEL T ,  SPINA KENNETH P ,  HALLAS ROBERT ,  ELLIOTT RICHARD L

IPC: C07H17/00 ,  A61K31/00 ,  A61K31/70 ,  A61K31/7042 ,  A61P31/00 ,  A61P31/04 ,  C07H17/08

Abstract: Compounds, or pharmaceutically acceptable salts and esters thereof, of formulae (I); (II); (III) or (IV) wherein A, B, D and E, R , R and Z are specifically defined, having antibacterial activity, pharmaceutical compositions containing said compounds, treatment of antibacterial infections with such compositions, and processes for the preparation of the compounds.