公开(公告)号：DE69631609D1

公开(公告)日：2004-03-25

申请号：DE69631609

申请日：1996-10-17

Applicant: ABBOTT LAB

Inventor： OR SUN ,  PHAN TAM ,  CHU T ,  SPINA P ,  HALLAS ROBERT ,  ELLIOTT L

IPC: C07H17/00 ,  A61K31/00 ,  A61K31/70 ,  A61K31/7042 ,  A61P31/00 ,  A61P31/04 ,  C07H17/08

Abstract: Compounds, or pharmaceutically acceptable salts and esters thereof, of formulae (I); (II); (III) or (IV) wherein A, B, D and E, R , R and Z are specifically defined, having antibacterial activity, pharmaceutical compositions containing said compounds, treatment of antibacterial infections with such compositions, and processes for the preparation of the compounds.

公开(公告)号：DE69631609T2

公开(公告)日：2005-01-05

申请号：DE69631609

申请日：1996-10-17

Applicant: ABBOTT LAB

Inventor： OR SUN ,  PHAN TAM ,  CHU T ,  SPINA P ,  HALLAS ROBERT ,  ELLIOTT L

IPC: C07H17/00 ,  A61K31/00 ,  A61K31/70 ,  A61K31/7042 ,  A61P31/00 ,  A61P31/04 ,  C07H17/08

Abstract: Compounds, or pharmaceutically acceptable salts and esters thereof, of formulae (I); (II); (III) or (IV) wherein A, B, D and E, R , R and Z are specifically defined, having antibacterial activity, pharmaceutical compositions containing said compounds, treatment of antibacterial infections with such compositions, and processes for the preparation of the compounds.

公开(公告)号：DE69830739T2

公开(公告)日：2006-04-20

申请号：DE69830739

申请日：1998-10-29

Applicant: ABBOTT LAB

Inventor： PHAN TAM ,  OR SUN ,  CHU T ,  PLATTNER J ,  CHEN YAN ,  CLARK F

IPC: C07H17/08 ,  A61K31/70 ,  A61K31/7042 ,  A61K31/7048 ,  A61P31/04

Abstract: Novel 2-halo-6-O-substituted ketolide derivatives and pharmaceutically acceptable salts and esters thereof having antibacterial activity having formula (I) or (II), compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier, a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for their preparation.

公开(公告)号：DE69830739D1

公开(公告)日：2005-08-04

申请号：DE69830739

申请日：1998-10-29

Applicant: ABBOTT LAB

Inventor： PHAN TAM ,  OR SUN ,  CHU T ,  PLATTNER J ,  CHEN YAN ,  CLARK F

IPC: A61K31/7042 ,  A61K31/7048 ,  A61P31/04 ,  C07H17/08 ,  A61K31/70

Abstract: Novel 2-halo-6-O-substituted ketolide derivatives and pharmaceutically acceptable salts and esters thereof having antibacterial activity having formula (I) or (II), compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier, a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for their preparation.