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公开(公告)号：WO2011047262A4
公开(公告)日：2011-11-10
申请号：PCT/US2010052843
申请日：2010-10-15
Applicant: ABBOTT LAB , GHAYUR TARIQ , KAMATH RAJESH V , LIU JUNJIAN , HONORE MARIE P
Inventor： GHAYUR TARIQ , KAMATH RAJESH V , LIU JUNJIAN , HONORE MARIE P
CPC classification number: C07K16/00 , C07K16/22 , C07K16/241 , C07K16/245 , C07K16/2866 , C07K16/44 , C07K16/46 , C07K2317/21 , C07K2317/31 , C07K2317/56 , C07K2317/73 , C07K2317/76
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
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公开(公告)号：WO2011028811A3
公开(公告)日：2011-04-28
申请号：PCT/US2010047543
申请日：2010-09-01
Applicant: ABBOTT LAB , GHAYUR TARIQ , LIU JUNJIAN , MANOJ SHARMILA , BROPHY SUSAN E
Inventor： GHAYUR TARIQ , LIU JUNJIAN , MANOJ SHARMILA , BROPHY SUSAN E
CPC classification number: C07K16/468 , A61K45/06 , C07K16/00 , C07K16/2803 , C07K16/2809 , C07K16/2863 , C07K16/2887 , C07K16/30 , C07K16/44 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/515 , C07K2317/64 , C07K2317/732 , C07K2317/92
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
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公开(公告)号：EP2491129A4
公开(公告)日：2013-05-29
申请号：EP10825739
申请日：2010-10-22
Applicant: ABBOTT LAB
Inventor： GHAYUR TARIQ , MORGAN-LAPPE SUSAN E , REILLY EDWARD B , KINGSBURY GILLIAN A , PHILLIPS ANDREW , WANG JIEYI , BELL RANDY L , NORVELL SUZANNE M , LI YINGCHUN , LIU JUNJIAN , YING HUA , LIU ZHIHONG
CPC classification number: C07K16/22 , A61K2039/505 , C07K16/28 , C07K16/2863 , C07K16/32 , C07K16/468 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2319/00
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
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公开(公告)号：WO2011163478A4
公开(公告)日：2012-07-05
申请号：PCT/US2011041633
申请日：2011-06-23
Applicant: ABBOTT LAB , GHAYUR TARIQ , LIU JUNJIAN , JAKWAY JAMES J , TALANIAN ROBERT V , BENATUIL LORENZO
Inventor： GHAYUR TARIQ , LIU JUNJIAN , JAKWAY JAMES J , TALANIAN ROBERT V , BENATUIL LORENZO
IPC: A61K39/395 , C07K16/00 , C12P21/02
CPC classification number: C07K16/2875 , C07K16/241 , C07K16/468 , C07K2317/31 , C07K2317/64
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
Abstract translation: 本发明涉及工程化的多价和多特异性结合蛋白，制备方法，具体涉及用于预防，诊断和/或治疗疾病的用途。
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公开(公告)号：WO2012018790A3
公开(公告)日：2012-05-31
申请号：PCT/US2011046233
申请日：2011-08-02
Applicant: ABBOTT LAB , GHAYUR TARIQ , LIU JUNJIAN , ISAKSON PETER C
Inventor： GHAYUR TARIQ , LIU JUNJIAN , ISAKSON PETER C
IPC: C07K16/00
CPC classification number: C07K16/244 , A61K39/3955 , A61K45/06 , A61K47/6845 , A61K49/00 , A61K51/1021 , C07K16/241 , C07K16/245 , C07K16/468 , C07K2317/35 , C07K2317/76 , C07K2317/92 , C07K2317/94 , G01N33/53 , G01N33/56966 , G01N33/6857 , G01N33/6869 , G01N2333/54 , G01N2333/545 , G01N2800/24 , G01N2800/7028
Abstract: Engineered multivalent and multispecific binding proteins, methods of making, and their uses in the prevention, diagnosis, and/or treatment of disease are provided.
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Patent Agency Ranking
公开(公告)号：WO2012006490A3
公开(公告)日：2012-04-26
申请号：PCT/US2011043297
申请日：2011-07-08
Applicant: ABBOTT LAB , GHAYUR TARIQ , LIU JUNJIAN
Inventor： GHAYUR TARIQ , LIU JUNJIAN
CPC classification number: C07K16/468 , A61K39/3955 , A61K45/06 , A61K47/6845 , C07K16/22 , C07K16/2863 , C07K16/2887 , C07K16/2896 , C07K2317/24 , C07K2317/31 , C07K2317/64 , C07K2317/73 , C07K2317/76 , C07K2317/92 , G01N33/6872
Abstract: Methods of making engineered multivalent and multi-specific binding proteins, and using the binding proteins in the prevention, diagnosis, and/or treatment of disease are provided. The multivalent binding proteins may contain more than one linked heavy chain and/or light chain variable regions joined by a constant region to an Fc region. The multivalent binding proteins may bind to a number of cytokines, hormones, growth factors, small molecules or cell surface receptors, including NGF and any of a number of small molecules, growth factors, cytokines, hormones or cell surface receptors.
Abstract translation: 提供了制造工程化多价和多特异性结合蛋白的方法，并且使用该结合蛋白预防，诊断和/或治疗疾病。 多价结合蛋白可含有超过一个连接的重链和/或轻链可变区，其通过恒定区连接至Fc区。 多价结合蛋白可以结合许多细胞因子，激素，生长因子，小分子或细胞表面受体，包括NGF和许多小分子，生长因子，细胞因子，激素或细胞表面受体中的任何一种。
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公开(公告)号：WO2011059755A3
公开(公告)日：2011-07-28
申请号：PCT/US2010054521
申请日：2010-10-28
Applicant: ABBOTT LAB , GHAYUR TARIQ , SALFELD JOCHEN G , MCPHERSON MICHAEL J , HARRIS MARIA C , LIU JUNJIAN , ISAKSON PETER C , GU JIJIE
Inventor： GHAYUR TARIQ , SALFELD JOCHEN G , MCPHERSON MICHAEL J , HARRIS MARIA C , LIU JUNJIAN , ISAKSON PETER C , GU JIJIE
IPC: C07K16/00 , A61K39/395
CPC classification number: C07K16/241 , C07K16/22 , C07K16/2803 , C07K16/2875 , C07K16/44 , C07K16/468 , C07K2317/31 , C07K2317/73
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
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公开(公告)号：WO2011050262A3
公开(公告)日：2011-06-30
申请号：PCT/US2010053730
申请日：2010-10-22
Applicant: ABBOTT LAB , GHAYUR TARIQ , MORGAN-LAPPE SUSAN E , REILLY EDWARD B , KINGSBURY GILLIAN A , PHILLIPS ANDREW , WANG JIEYI , BELL RANDY L , NORVELL SUZANNE M , LI YINGCHUN , LIU JUNJIAN , YING HUA , LIU ZHIHONG
Inventor： GHAYUR TARIQ , MORGAN-LAPPE SUSAN E , REILLY EDWARD B , KINGSBURY GILLIAN A , PHILLIPS ANDREW , WANG JIEYI , BELL RANDY L , NORVELL SUZANNE M , LI YINGCHUN , LIU JUNJIAN , YING HUA , LIU ZHIHONG
IPC: C12P21/08
CPC classification number: C07K16/22 , A61K2039/505 , C07K16/28 , C07K16/2863 , C07K16/32 , C07K16/468 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2319/00
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
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公开(公告)号：WO2010127294A2
公开(公告)日：2010-11-04
申请号：PCT/US2010033246
申请日：2010-04-30
Applicant: ABBOTT LAB , GHAYUR TARIQ , BROPHY SUSAN E , DEVARE SUSHIL G , GRENIER FRANK C , MOORE JEFFREY A , RUAN QIAOQIAO , TETIN SERGEY Y , STEINHAUS JENNIFER M , LIU JUNJIAN , ALI SALMAN , SYED HINA N
Inventor： GHAYUR TARIQ , BROPHY SUSAN E , DEVARE SUSHIL G , GRENIER FRANK C , MOORE JEFFREY A , RUAN QIAOQIAO , TETIN SERGEY Y , STEINHAUS JENNIFER M , LIU JUNJIAN , ALI SALMAN , SYED HINA N
IPC: A61K39/395 , C12P21/06
CPC classification number: C07K16/18 , C07K16/1045 , C07K16/244 , C07K16/26 , C07K2317/31 , C07K2317/56 , C07K2317/71 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/92 , C07K2319/00
Abstract: Engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
Abstract translation: 工程化的多价和多特异性结合蛋白，制备方法，特别是其在预防，诊断和/或治疗疾病中的用途。
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公开(公告)号：WO2009134776A3
公开(公告)日：2009-12-23
申请号：PCT/US2009041945
申请日：2009-04-28
Applicant: ABBOTT LAB , GHAYUR TARIQ , MORGAN-LAPPE SUSAN E , REILLY EDWARD B , KINGSBURY GILLIAN A , PHILLIPS ANDREW , WANG JIEYI , BELL RANDY L , NORVELL SUZANNE M , LI YINGCHUN , LIU JUNJIAN , YING HUA
Inventor： GHAYUR TARIQ , MORGAN-LAPPE SUSAN E , REILLY EDWARD B , KINGSBURY GILLIAN A , PHILLIPS ANDREW , WANG JIEYI , BELL RANDY L , NORVELL SUZANNE M , LI YINGCHUN , LIU JUNJIAN , YING HUA
IPC: A61K39/00
CPC classification number: C07K16/468 , A61K39/39533 , A61K45/06 , A61K2039/505 , C07K16/22 , C07K16/28 , C07K16/2863 , C07K16/32 , C07K2317/31 , C07K2317/565 , C07K2317/64 , C07K2317/71 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/92 , C07K2319/00 , G01N33/6872 , G01N33/74 , G01N2333/515 , G01N2333/705 , Y10S435/81
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
Abstract translation: 本发明涉及工程化的多价和多特异性结合蛋白，制备方法，特别涉及它们在疾病的预防，诊断和/或治疗中的用途。
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