-
公开(公告)号：EP1090009A2
公开(公告)日：2001-04-11
申请号：EP99926157.1
申请日：1999-06-03
Applicant: ABBOTT LABORATORIES
Inventor： STEWART, Andrew, O. , BOYD, Steven, A. , ARENDSEN, David, L. , BHATIA, Pramila , CONDROSKI, Kevin, R. , FREEMAN, Jennifer, C. , GUNAWARDANA, Indrani, W. , ZHU, Gui-Dong , LARTEY, Kraig , MCCARTY, Catherine, M. , MORT, Nicholas, A. , PATEL, Meena V. , STAEGER, Michael, A. , STOUT, David, M.
IPC: C07D495/04 , C07D498/04 , C07D513/04 , C07D471/04 , C07D491/04 , A61K31/44 , A61K31/50 , A61K31/505
CPC classification number: C07D471/04 , C07D491/04 , C07D495/04 , C07D513/04
Abstract: Compounds having Formula (I) are useful for treating inflammation. Also disclosed are pharmaceutical compositions comprising compouns of Formula (I), and methods of inhibiting/treating inflammatory diseases in a mammal.
Abstract translation: 具有式（I）的化合物可用于治疗炎症。 还公开了包含式（I）化合物的药物组合物，以及在哺乳动物中抑制/治疗炎性疾病的方法。
-
公开(公告)号：EP2183248A2
公开(公告)日：2010-05-12
申请号：EP08781874.6
申请日：2008-07-16
Applicant: Abbott Laboratories
Inventor： GANDHI, Virajkumar B , GIRANDA, Vincent L , GONG, Jianchun , PENNING, Thomas D , ZHU, Gui-Dong
IPC: C07D417/14 , A61K31/427 , A61P35/00
CPC classification number: C07D417/14 , C07D405/14 , C07D409/14 , C07D413/14
Abstract: Compounds which inhibit the activity of poly(ADP-ribose)polymerase (PARP), compositions containing the compounds and methods of treating diseases using them are disclosed.
-
Patent Agency Ranking13.发明公开SUBSTITUTED 1H-BENZIMIDAZOLE-4-CARBOXAMIDES ARE POTENT PARP INHIBITORS 有权取代的1H-苯并咪唑-4-甲酰胺是有效的PARP抑制剂
公开(公告)号：EP1966157A2
公开(公告)日：2008-09-10
申请号：EP06837694.6
申请日：2006-11-15
Applicant: ABBOTT LABORATORIES
Inventor： PENNING, Thomas D. , THOMAS, Sheela A. , ZHU, Gui-Dong , GONG, Jianchun , GIRANDA, Vincent L. , GANDHI, Viraj B.
IPC: C07D235/18
CPC classification number: C07D235/18 , C07D409/04 , C07D413/04 , C07D417/04
Abstract: Compounds of Formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I), methods of treatment comprising compounds of Formula (I), and methods of inhibiting the PARP enzyme comprising compounds of Formula (I).
-
14.发明授权CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS 有权ZELLADHÄSION-和抗炎免疫CONNECTIONS
公开(公告)号：EP1140814B1
公开(公告)日：2005-05-25
申请号：EP99966709.0
申请日：1999-12-29
Applicant: ABBOTT LABORATORIES
Inventor： LINK, James , LIU, Gang , PEI, Zhonghua , VON GELDERN, Tom , WINN, Martin , XIN, Zhili , BOYD, Steven, A. , JAE, Hwan-Soo , LYNCH, John, K. , ZHU, Gui-Dong , FREEMAN, Jennifer, C. , GUNAWARDANA, Indrani, W. , STAEGER, Michael, A.
IPC: C07C323/00
CPC classification number: C07D207/27 , C07C323/62 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07D207/09 , C07D207/14 , C07D207/20 , C07D207/22 , C07D207/26 , C07D209/08 , C07D209/18 , C07D211/22 , C07D211/26 , C07D211/42 , C07D211/46 , C07D211/54 , C07D211/60 , C07D211/62 , C07D211/74 , C07D213/74 , C07D213/75 , C07D213/81 , C07D215/36 , C07D217/06 , C07D235/26 , C07D239/42 , C07D241/04 , C07D241/24 , C07D243/08 , C07D265/30 , C07D295/13 , C07D295/185 , C07D295/205 , C07D295/215 , C07D295/26 , C07D295/32 , C07D307/52 , C07D307/68 , C07D317/58 , C07D317/62 , C07D319/18 , C07D319/20 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/12 , C07D405/12 , C07D405/14 , C07D413/04 , C07D413/14 , C07D471/10 , C07D487/08 , C07D491/10
Abstract: The present invention relates to novel cinnamide compounds that are useful for treating inflammatory and immune diseases, to pharmaceutical compositions containing these compounds, and to methods of inhibiting inflammation or suppressing immune response in a mammal.
-
15.发明授权CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS 有权ZELLADHÄSIONINHIBIERENDEENTZÜNDUNGSHEMMENDEUND IMMUNSUPPRIVEIVE VERBINDUNGEN
公开(公告)号：EP1165505B1
公开(公告)日：2004-09-08
申请号：EP00921654.0
申请日：2000-04-03
Applicant: ABBOTT LABORATORIES
Inventor： LINK, James , LIU, Gang , PEI, Zhonghua , VON GELDERN, Thomas, W. , WINN, Martin , XIN, Zhili , WANG, Sheldon , BOYD, Steven, A. , ZHU, Gui-Dong , FREEMAN, Jennifer, C. , GUNAWARDANA, Indrani, W. , STAEGER, Michael, A. , JAE, Hwan-Soo , LYNCH, John, K.
IPC: C07C323/62 , C07D233/61 , C07D207/26 , C07D295/18 , C07D213/74 , C07D211/22 , C07D207/14 , C07D211/46 , C07D211/62 , C07D211/60 , C07D401/04 , C07D217/02 , C07D307/68 , C07D295/26 , C07D317/66 , C07D209/08 , C07D295/205 , C07D401/12 , A61K31/165 , A61K31/33 , A61P29/00
CPC classification number: C07D207/27 , C07C323/62 , C07C2601/02 , C07D205/04 , C07D207/09 , C07D207/14 , C07D207/16 , C07D209/08 , C07D211/20 , C07D211/22 , C07D211/46 , C07D211/60 , C07D211/62 , C07D213/40 , C07D213/74 , C07D213/81 , C07D217/02 , C07D217/06 , C07D231/12 , C07D233/56 , C07D241/04 , C07D249/08 , C07D295/185 , C07D295/26 , C07D307/68 , C07D317/66 , C07D401/04 , C07D401/12
Abstract: The present invention relates to cinnamide compounds of formula (I), in which at least one of R1 to R5 is a "cis-cinnamide" (a) or a "trans-cinnamide" (b) and the other variables are as defined in the claims, that are useful for treating inflammatory and immune diseases, to pharmaceutical compositions containing these compounds and to methods of inhibiting inflammation or suppressing immune response in a mammal.
Abstract translation: 本发明涉及式（I）的肉桂酰胺化合物，其中R 1至R 5中的至少一个为“顺式 - 酰胺”（a）或“反式肉桂酰胺”（b），其它变量如 可用于治疗炎症和免疫疾病的权利要求，含有这些化合物的药物组合物和抑制哺乳动物炎症或抑制免疫应答的方法。
-
公开(公告)号：EP1181296A1
公开(公告)日：2002-02-27
申请号：EP99931986.6
申请日：1999-06-28
Applicant: ABBOTT LABORATORIES
Inventor： ARENDSEN, David, L. , BHATIA, Pramila , BOYD, Steven, A. , CONDROSKI, Kevin, R. , FREEMAN, Jennifer, C. , GUNAWARDANA, Indrani, W. , LARTEY, Kraig , MCCARTY, Catherine, M. , MORT, Nicholas, A. , PATEL, Meena V. , STAEGER, Michael, A. , STEWART, Andrew, O. , STOUT, David, M. , ZHU, Gui-Dong
IPC: C07D495/04
CPC classification number: C07D471/04 , C07D491/04 , C07D495/04 , C07D513/04
Abstract: Compounds having formula (I) are useful for treating inflammation. Also disclosed are pharmaceutical compositions comprising compounds of formula (I), and methods of inhibiting/treating inflammatory diseases in a mammal.
Abstract translation: 具有式（I）的化合物可用于治疗炎症。 还公开了包含式（I）化合物的药物组合物，以及在哺乳动物中抑制/治疗炎性疾病的方法。
-
17.发明公开
公开(公告)号：EP1140814A2
公开(公告)日：2001-10-10
申请号：EP99966709.0
申请日：1999-12-29
Applicant: ABBOTT LABORATORIES
Inventor： LINK, James , LIU, Gang , PEI, Zhonghua , VON GELDERN, Tom , WINN, Martin , XIN, Zhili , BOYD, Steven, A. , JAE, Hwan-Soo , LYNCH, John, K. , ZHU, Gui-Dong , FREEMAN, Jennifer, C. , GUNAWARDANA, Indrani, W. , STAEGER, Michael, A.
IPC: C07C323/00
CPC classification number: C07D207/27 , C07C323/62 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07D207/09 , C07D207/14 , C07D207/20 , C07D207/22 , C07D207/26 , C07D209/08 , C07D209/18 , C07D211/22 , C07D211/26 , C07D211/42 , C07D211/46 , C07D211/54 , C07D211/60 , C07D211/62 , C07D211/74 , C07D213/74 , C07D213/75 , C07D213/81 , C07D215/36 , C07D217/06 , C07D235/26 , C07D239/42 , C07D241/04 , C07D241/24 , C07D243/08 , C07D265/30 , C07D295/13 , C07D295/185 , C07D295/205 , C07D295/215 , C07D295/26 , C07D295/32 , C07D307/52 , C07D307/68 , C07D317/58 , C07D317/62 , C07D319/18 , C07D319/20 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/12 , C07D405/12 , C07D405/14 , C07D413/04 , C07D413/14 , C07D471/10 , C07D487/08 , C07D491/10
Abstract: The present invention relates to novel cinnamide compounds that are useful for treating inflammatory and immune diseases, to pharmaceutical compositions containing these compounds, and to methods of inhibiting inflammation or suppressing immune response in a mammal.
Abstract translation: 本发明涉及可用于治疗炎症和免疫疾病的新型肉桂酰胺化合物，含有这些化合物的药物组合物，以及抑制哺乳动物炎症或抑制免疫应答的方法。
-
-
-
-
-
-
Search Results
17
records
(took 0.053 seconds)
